insta senz ointment - Gabapentin (8% w/w) + Capsaicin Based Rubefacients (0.035% w/w) medicine

Encrozep Plus Ointment: A Topical Solution for Neuropathic Pain

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🏭 Shilpex Pharmysis 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for some neuropathic pain conditions; limited for others.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe burning, blistering, or peeling of the skin at the application site.
  • Swelling of the face, lips, tongue, or throat, or difficulty breathing.
  • Signs of an allergic reaction such as a widespread rash or hives.
  • Dizziness, drowsiness, or confusion that does not go away.
  • Pain that worsens or does not improve after several weeks of use.
  • New or unusual symptoms such as muscle weakness or difficulty walking.

If experiencing severe symptoms, call emergency services immediately.

What is insta senz ointment used for?

This medicine is a topical ointment containing gabapentin and capsaicin-based rubefacients. It is used to relieve localized neuropathic pain by reducing abnormal nerve firing and desensitizing pain nerve endings. Apply it thinly to the affected skin as directed by your doctor.

  • Generic Name: Gabapentin (8% w/w) + Capsaicin Based Rubefacients (0.035% w/w)
  • Manufacturer: Shilpex Pharmysis
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 insta senz ointment के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल ऑइंटमेंट है जिसमें गैबापेंटिन और कैप्साइसिन आधारित रूबेफेशिएंट्स होते हैं। इसका उपयोग त्वचा पर लगाकर स्थानीय न्यूरोपैथिक दर्द को कम करने के लिए किया जाता है, जैसे कि डायबिटिक न्यूरोपैथी या दाद के बाद होने वाला दर्द। यह दर्द को कम करने और जलन को शांत करने में मदद करता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, लालिमा, खुजली या सूखापन शामिल हैं। ये आमतौर पर अस्थायी होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर त्वचा पर छाले पड़ें, सूजन हो या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर ही लगाएं। आंखों, मुंह और नाक से दूर रखें। टूटी या घायल त्वचा पर न लगाएं। उपयोग से पहले और बाद में हाथ धोएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 insta senz ointment Uses & Benefits

[{"condition":"Diabetic peripheral neuropathy","description":"This medicine is applied topically to relieve burning, shooting, or stabbing pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Moderate"},{"condition":"Post-herpetic neuralgia","description":"It helps reduce persistent nerve pain that remains after a shingles rash has healed.","evidence":"Moderate"},{"condition":"Localized neuropathic pain","description":"Used for various types of localized nerve pain, such as that following surgery or trauma.","evidence":"Limited"}]

Off-label uses: [{"condition":"Osteoarthritis pain","description":"Sometimes applied topically to provide additional pain relief in osteoarthritis, though evidence is limited.","evidence":"Limited"},{"condition":"Musculoskeletal pain","description":"May be used off-label for localized muscle or joint pain, but its role is not well established.","evidence":"Limited"}]

Primary treatment for: Neuropathic pain

Also treats: Diabetic peripheral neuropathy, Post-herpetic neuralgia

📋 Drug Information

Generic Name(s)Gabapentin (8% w/w) + Capsaicin Based Rubefacients (0.035% w/w)
Brand Nameinsta senz ointment
ManufacturerShilpex Pharmysis
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Keep away from direct sunlight and moisture. Do not freeze.
Shelf LifeNot established from the available information. Check the packaging for the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine exactly as prescribed by your doctor, usually a thin layer to the affected area.
2
Wash your hands before and after application to prevent accidental contact with eyes or mouth.
3
Do not apply to broken or irritated skin, as this may increase irritation.
4
If you experience a burning sensation, it often decreases with continued use; if severe, stop and consult your doctor.
5
Avoid using heating pads or tight bandages over the treated area unless instructed.
6
Keep a diary of your pain levels to help your doctor assess the effectiveness of treatment.
7
Inform your doctor if you are taking any other medications, especially other pain relievers.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning or shooting pain in feet or hands
This medicine is commonly prescribed for diabetic peripheral neuropathy.
Likely Use
✅
Persistent pain after shingles
This medicine can help with post-herpetic neuralgia.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not intended for headache relief.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information. Topical gabapentin is generally considered to have minimal systemic absorption, but specific absorption data for this formulation are not available.
DistributionNot established from the available information. As a topical product, its distribution is primarily local to the application site.
Protein BindingNot established from the available information.
MetabolismNot established from the available information. Any systemically absorbed gabapentin is not significantly metabolized, but this is not confirmed for the topical route.
Half-LifeNot established from the available information.
ExcretionNot established from the available information. Systemically absorbed gabapentin is excreted unchanged by the kidneys, but this is not confirmed for the topical route.
BioavailabilityNot established from the available information. Topical bioavailability is expected to be low, but specific data are lacking.
Onset of ActionThe onset of pain relief may vary. Some patients report a warming sensation immediately after application, but noticeable pain relief may take several days to weeks of regular use.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action is not well established. The soothing effect may last for several hours after application, but pain relief may require consistent use.

How It Works

This medicine works through two complementary mechanisms. Gabapentin, the primary active ingredient, is thought to bind to the alpha-2-delta subunit of voltage-gated calcium channels on nerve cells. This action reduces the release of excitatory neurotransmitters and decreases abnormal nerve firing that contributes to neuropathic pain. Capsaicin, a component of the rubefacients, interacts with TRPV1 receptors on sensory nerve endings. Initially it causes a warming or burning sensation, but with repeated application it desensitizes these nerve endings, leading to reduced pain transmission. The rubefacient effect also increases local blood flow, which may help distribute the active ingredients and provide a soothing sensation.

Mechanism Steps

1
Gabapentin binding to calcium channels: Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels on nerve cells, reducing calcium influx and subsequent release of pain neurotransmitters.
2
Reduced neuronal excitability: By modulating calcium channels, gabapentin decreases the excitability of damaged nerves, which helps to dampen abnormal pain signals.
3
Capsaicin activation of TRPV1: Capsaicin binds to and activates TRPV1 receptors on sensory nerve endings, initially causing a burning or warming sensation.
4
Desensitization of pain fibers: Repeated application of capsaicin leads to desensitization of TRPV1-expressing nerve endings, reducing the transmission of pain signals to the brain.
5
Increased local blood flow: The rubefacient effect causes vasodilation, increasing blood flow to the application site, which may enhance comfort and aid in the local action of the medicine.

💡 How to Take insta senz ointment

Strength: Ointment containing Gabapentin 8% w/w and Capsaicin-based rubefacients 0.035% w/w.

1Wash your hands thoroughly before and after applying the ointment.
2Clean and dry the affected area of skin.
3Apply a thin layer of the ointment to the affected area.
4Gently rub it into the skin until it is absorbed.
5Do not cover the area with a tight bandage or heating pad unless instructed.
6Avoid touching your eyes, mouth, or nose immediately after application.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area of skin as directed by your doctor. The frequency and duration of use depend on the condition being treated and your response to therapy. Typically, it may be applied 2 to 4 times daily, but the exact dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended application frequency.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may use this medicine as directed by a doctor. No specific dose adjustment is typically required for topical use, but caution is advised due to potentially increased skin sensitivity.
Renal ImpairmentNo dose adjustment is typically required for topical use, as systemic absorption is minimal. However, consult your doctor if you have severe kidney disease.
Hepatic ImpairmentNo dose adjustment is typically required for topical use, as systemic absorption is minimal. However, consult your doctor if you have severe liver disease.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Follow your doctor's instructions and do not exceed the recommended application frequency.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of insta senz ointment

✅ Common Side Effects

Application site burning (Common (5-10%))
This is often temporary and decreases with continued use. If severe, wash the area gently and consult your doctor.
Application site redness (Common (5-10%))
Usually resolves on its own. Avoid applying to sensitive areas.
Application site itching (Common (5-10%))
Try not to scratch. If itching persists, consult your doctor.
Skin dryness (Uncommon (1-5%))
Use a moisturizer on unaffected skin. Consult doctor if severe.

🚨 Serious Side Effects

Severe skin reaction (blistering, peeling) (Rare (<0.1%))
Stop using the medicine and seek immediate medical attention.
Allergic reaction (swelling of face, lips, throat, difficulty breathing) (Rare (<0.1%))
Seek emergency medical help immediately.

⚠️ Rare Side Effects

Systemic effects from gabapentin (dizziness, drowsiness)
If you experience dizziness or drowsiness, avoid driving and consult your doctor.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to gabapentin, capsaicin, or any component of this medicine.","Application to broken or irritated skin.","Use in eyes or mucous membranes."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not apply to large areas of skin without medical advice.","Do not use with occlusive dressings or heating pads unless instructed.","Keep out of reach of children.","Consult a doctor if pain persists or worsens.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Not established from the available information. It is not known whether this medicine passes into breast milk. Consult your doctor before use while breastfeeding. Avoid applying to the breast area.

💊 Overdose Management

Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of gabapentin overdose may include dizziness, drowsiness, blurred vision, and difficulty breathing. Contact a poison control center or emergency room right away.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to the affected area of skin as directed by your doctor. Wash your hands thoroughly before and after applying the ointment, unless your hands are the treated area. Avoid contact with eyes, mouth, nose, and other mucous membranes. Do not apply to cuts, wounds, or irritated skin. Do not cover the treated area with a tight bandage or heating pad unless instructed. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not use more than the recommended amount or more often than prescribed. If your pain does not improve or worsens after a few weeks, contact your healthcare provider.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have more sensitive skin and are more prone to skin reactions. Use this medicine with caution and monitor for any signs of irritation. No specific dose adjustment is typically required for topical use, but consult your doctor if you have other health conditions.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. There is limited information on the safety of topical gabapentin and capsaicin during pregnancy. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before applying this medicine to the surgical area. It should not be applied to healing wounds or incisions unless specifically instructed.

🦷 Dental Procedures

This medicine is applied to the skin and is not expected to interfere with dental procedures. However, inform your dentist about all medications you are taking, including topical ones.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on your joints and nerves.
🥗
Engage in regular low-impact exercises like walking or swimming to improve circulation.
😴
Practice good foot care, especially if you have diabetes, to prevent injuries.
💧
Avoid smoking and limit alcohol, as these can worsen nerve pain.
🧘
Get adequate sleep to help your body recover and manage pain better.
🌞
Manage stress through relaxation techniques like deep breathing or meditation.

🏋️ Exercise Considerations

While using this medicine, you can generally continue your regular exercise routine. However, if you experience dizziness or drowsiness, avoid activities that require alertness, such as driving or operating heavy machinery. If you have neuropathy, choose low-impact exercises to prevent injury to your feet.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids, such as fish and flaxseeds, to help reduce inflammation.
Eat a balanced diet with plenty of fruits and vegetables to support nerve health.
Limit processed foods and added sugars, which can worsen inflammation.
Stay well hydrated to maintain healthy skin and overall well-being.
If you have diabetes, monitor your blood sugar levels and follow your diabetic diet.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to work. However, if you experience dizziness or drowsiness, avoid driving or operating machinery until you know how the medicine affects you. You can apply it at home before work or as needed during the day, but ensure you wash your hands after application to avoid transferring it to others or to your eyes.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your doctor. If your pain improves, your doctor may adjust the frequency or discontinue it. If you experience severe side effects or an allergic reaction, stop using it and seek medical attention immediately. If your pain does not improve after several weeks, consult your doctor for alternative treatments.

📅 Long-Term Use Effects

Long-term use of this medicine is generally considered safe for topical application, but prolonged use may lead to skin dryness, irritation, or sensitivity. There is no established information on systemic long-term effects from topical gabapentin. It is advisable to have periodic reviews with your doctor to assess the continued need for treatment and to monitor for any skin changes.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can help improve strength, flexibility, and reduce pain for certain neuropathic conditions.

Evidence: Moderate
Transcutaneous electrical nerve stimulation (TENS)

May provide temporary relief for localized nerve pain.

Evidence: Limited
Oral medications

Oral gabapentinoids or antidepressants may be prescribed for more widespread neuropathic pain.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, inform your healthcare provider about all medicines you are using before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C).

❌ DON'T

Do not refrigerate unless specified.

✅ DO

Keep in the original container.

❌ DON'T

Do not transfer to unmarked containers.

✅ DO

Keep away from direct sunlight.

❌ DON'T

Do not store in the bathroom cabinet.

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in its original packaging with the prescription label intact. Carry a copy of your prescription in case you need to show it at customs or security. Store it at room temperature and protect it from extreme heat or cold. If you are flying, pack it in your carry-on luggage to avoid temperature fluctuations in checked baggage. There are no specific time zone adjustments needed for topical application, but try to maintain your regular application schedule as closely as possible.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with diabetic neuropathy in his feet
He had been suffering from burning and shooting pain in both feet for over a year. His doctor prescribed this medicine to apply twice daily. After about three weeks, he noticed a significant reduction in the burning sensation, especially at night. He experienced mild redness initially, which faded with continued use. He found it helpful to apply the ointment after washing his feet and before bedtime.
💡 Lesson: Consistent daily application is key to achieving pain relief, and mild skin reactions often subside with continued use.
👤 A 65-year-old woman with post-herpetic neuralgia on her torso
After recovering from shingles, she was left with persistent stabbing pain on her side. She was prescribed this ointment to apply three times a day. She initially felt a warming sensation, which she found soothing. Over four weeks, the pain gradually decreased, allowing her to sleep better and resume her daily activities. She was careful to avoid applying it near her eyes and washed her hands thoroughly after each use.
💡 Lesson: Topical treatment can provide significant relief for post-herpetic neuralgia, but it requires patience and consistent use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Some people may notice a warming sensation immediately, but noticeable pain relief may take several days to weeks of regular use. It is important to apply it consistently as directed.

Q: Can I apply this medicine to my face?

A: No, this medicine should not be applied to the face or near the eyes, mouth, or mucous membranes unless specifically instructed by your doctor.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.

Q: Is it safe to use this medicine with other pain relievers?

A: Generally, topical application has minimal systemic absorption, so interactions are unlikely. However, inform your doctor about all medications you are taking to be safe.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long can I use this ointment?
  • Will it interact with my other medications?
  • Can I drive after applying this medicine?
  • What if I accidentally swallow some?
  • Is it safe to use during pregnancy?

🔄 Substitutes for insta senz ointment

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally.
    Fact: This medicine is for external use only and must not be swallowed.
  • Myth: More ointment means faster relief.
    Fact: Applying more than directed does not improve results and may increase side effects.
  • Myth: It works immediately.
    Fact: Pain relief may take several days to weeks of regular use.

📊 Comparison with Similar Medicines

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