Keto-B Cream: Complete Guide to Uses, Side Effects, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction with swelling of the face, lips, or throat, or difficulty breathing.
- Signs of a worsening infection such as increased pain, swelling, redness, pus, or fever.
- Skin thinning, stretch marks, or easy bruising in the treated area.
- Symptoms of adrenal suppression such as extreme tiredness, weakness, dizziness, or nausea.
- No improvement after 2 weeks of regular use.
- New rash or severe itching that was not present before starting the cream.
- Blurred vision or eye pain if the cream accidentally gets into the eyes.
If experiencing severe symptoms, call emergency services immediately.
What is keto-b cream used for?
This medicine is a topical cream containing beclometasone (a steroid) and ketoconazole (an antifungal). It is used to treat inflamed fungal skin infections like ringworm and jock itch. Apply a thin layer to the affected area as prescribed, usually once or twice daily. Do not use it for more than a few weeks without medical advice.
- Generic Name: Beclometasone (0.025% w/w) + Ketoconazole (2% w/w)
- Manufacturer: Med Manor Organics Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 keto-b cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें बेक्लोमेथासोन (एक स्टेरॉयड) और केटोकोनाज़ोल (एक एंटीफंगल) शामिल हैं। इसका उपयोग फंगल संक्रमण के कारण होने वाली सूजन, खुजली और लालिमा के इलाज के लिए किया जाता है, जैसे दाद, खाज-खुजली, और पैरों में फंगस। यह क्रीम फंगस को मारती है और साथ ही सूजन और खुजली को कम करती है। इसे डॉक्टर के निर्देशानुसार प्रभावित त्वचा पर पतली परत में लगाएं। इसे चेहरे, जांघों के बीच या बगल में बिना डॉक्टर की सलाह के न लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, सूखापन या लालिमा शामिल हैं। ये आमतौर पर अस्थायी होते हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं, या त्वचा का रंग बदल सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर प्रतिक्रिया हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस क्रीम को सिर्फ बाहरी उपयोग के लिए है, इसे निगलें नहीं। लगाने से पहले और बाद में हाथ धोएं। प्रभावित जगह को साफ और सूखा करें, फिर पतली परत में लगाएं। आंखों, मुंह और नाक से संपर्क से बचें। बिना डॉक्टर की सलाह के इसे चेहरे, जांघों के बीच या बगल में न लगाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। दूसरों के साथ साझा न करें।
💊 keto-b cream Uses & Benefits
[{"condition":"Tinea corporis (ringworm of the body)","description":"Treats fungal infection of the body skin that is accompanied by inflammation, itching, and redness.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch)","description":"Used for fungal infection in the groin area when inflammation is prominent, but only under medical supervision due to risk of skin thinning.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"Helps clear fungal infection between the toes and on the soles while reducing itching and burning.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis","description":"Treats yeast infections of the skin, especially in moist folds, when associated with redness and irritation.","evidence":"Well-established"},{"condition":"Fungal skin infections with eczematous inflammation","description":"Provides relief when a fungal infection is mixed with an eczema-like inflammatory reaction.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Seborrheic dermatitis","description":"Sometimes prescribed off-label when both yeast and inflammation are contributing to scalp or facial flaking.","evidence":"Limited"},{"condition":"Fungal infection with contact dermatitis","description":"May be used short-term when a fungal infection is complicated by an allergic skin reaction.","evidence":"Limited"}]
Primary treatment for: Inflammatory fungal skin infections
Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Cutaneous candidiasis, Fungal infection with eczema-like inflammation
📋 Drug Information
| Generic Name(s) | Beclometasone (0.025% w/w) + Ketoconazole (2% w/w) |
| Brand Name | keto-b cream |
| Manufacturer | Med Manor Organics Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C. Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. Topical antifungal-corticosteroid combinations are generally not recommended as first-line therapy by some guidelines due to risk of steroid side effects, but they may be used for short periods in inflammatory fungal infections under medical supervision. |
| ICMR Guideline | Not established from the available information. Consult a doctor for appropriate treatment of fungal skin infections according to Indian guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Ketoconazole blocks the synthesis of ergosterol, an essential component of the fungal cell membrane, by inhibiting the fungal cytochrome P450 enzyme 14-alpha-demethylase. This damages the fungal membrane and stops fungal growth. Beclometasone binds to glucocorticoid receptors in the skin, reducing the release of inflammatory chemicals and suppressing the local immune response. Together, they treat the fungal infection while rapidly reducing itching, redness, and swelling.
Mechanism Steps
💡 How to Take keto-b cream
Strength: Topical cream containing beclometasone 0.025% w/w and ketoconazole 2% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected skin area once or twice daily, or as directed by your doctor. The exact frequency and duration depend on the type and severity of the infection and the area treated. Usually, treatment is continued for 2 to 4 weeks, but your doctor will decide the right duration. Do not use more than prescribed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 12 years unless specifically prescribed by a doctor. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of topical corticosteroids. Use the smallest amount that works for the shortest time. Consult your doctor for proper guidance. |
| Renal Impairment | No dose adjustment is needed for topical use in patients with kidney disease. However, if you have severe kidney disease, consult your doctor before use. |
| Hepatic Impairment | No dose adjustment is needed for topical use in patients with liver disease. However, if you have severe liver disease, consult your doctor before use. |
| Maximum Daily Dose | The maximum daily dose depends on the area treated and the strength of the cream. Do not exceed the frequency and duration prescribed by your doctor. Generally, apply only enough to cover the affected area thinly once or twice daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of keto-b cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ritonavir | Major | |
| Clarithromycin | Major | |
| Itraconazole | Major | |
| Rifampicin | Major | |
| Carbamazepine | Major | |
| Phenytoin | Major | |
| Other topical corticosteroids | Moderate | |
| Topical antibiotics | Moderate | |
| Cosmetics with harsh chemicals | Minor |
🚨 Major Interactions
- Oral anticoagulants (e.g., warfarin)
- CYP3A4 inhibitors (e.g., ritonavir, clarithromycin, itraconazole)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
⚡ Moderate Interactions
- Other topical corticosteroids
- Topical antifungals or antibiotics
- Cosmetics or moisturizers containing harsh chemicals
🍷 Alcohol Interaction
Alcohol is not expected to interact directly with this topical cream. However, alcohol may worsen certain skin conditions or increase inflammation. It is best to limit alcohol intake while treating a skin infection and to follow your doctor's advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to beclometasone, ketoconazole, or any ingredient in the cream","Bacterial skin infections (unless a doctor has also prescribed an antibiotic)","Viral skin infections such as chickenpox, herpes simplex, or shingles","Fungal infections that are not inflammatory and do not require a steroid","Acne, rosacea, or perioral dermatitis","Use on the face, groin, or underarms unless specifically directed by a doctor","Use in children under 12 years without medical advice"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not use on large areas or for longer than prescribed without medical review.","Do not cover the treated area with tight bandages or dressings unless instructed.","If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use.","Keep out of reach of children.","Do not use on broken or infected skin unless directed by a doctor.","If symptoms do not improve after 2 weeks, consult your doctor.","Do not share this medicine with others."]
🤱 Lactation Safety
It is not known whether topical beclometasone or ketoconazole passes into breast milk in significant amounts. To be safe, do not apply this cream to the breast area before breastfeeding. If applied to other areas, wash hands thoroughly before handling the baby. Consult your doctor before use while breastfeeding.
💊 Overdose Management
This medicine is for topical use. Accidental swallowing of small amounts is unlikely to cause serious harm, but if a large amount is swallowed, seek medical attention immediately. Overuse on the skin can lead to increased absorption and steroid side effects. If you have applied too much or used it for too long, wash the area gently and consult your doctor. Treatment of overdose is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine exactly as prescribed by your doctor. Wash your hands before and after application. Clean and dry the affected skin gently before applying a thin layer. Do not cover the area with tight bandages or dressings unless your doctor tells you to. Avoid contact with eyes, mouth, and other mucous membranes. Do not use this medicine for longer than the recommended duration without medical review. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have thinner skin and are more susceptible to the side effects of topical corticosteroids, such as skin thinning and easy bruising. Use the smallest amount that works for the shortest time. Consult your doctor for proper guidance and monitoring.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. Topical beclometasone and ketoconazole are generally considered low risk when used in small amounts for short periods, but they should only be used if clearly needed. Avoid extensive application or prolonged use.
🏥 Post-Surgery Considerations
If you have recently had surgery, do not apply this cream to surgical wounds or broken skin unless specifically instructed by your doctor. Consult your doctor before using this medicine after surgery.
🦷 Dental Procedures
This medicine is applied to the skin and does not directly affect dental procedures. However, if you have a skin infection near the mouth, avoid applying the cream inside the mouth or on the lips unless prescribed. Inform your dentist about all medicines you are using.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light exercise, but avoid activities that cause excessive sweating or friction on the treated area until the infection clears. If you have athlete's foot, keep your feet dry and wear clean, breathable footwear during exercise. Avoid swimming pools or communal showers until the infection is fully treated to prevent spreading it to others.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine does not affect your ability to drive or operate machinery. You can continue your normal daily activities. However, if the infection is in an area that causes discomfort while sitting or walking, you may need to take short breaks and keep the area clean and dry. Avoid activities that cause excessive sweating until the infection improves.
🛑 When to Stop This Medicine
Stop using this medicine when the prescribed course is complete or when your doctor tells you to stop. Do not stop early even if symptoms improve, as the infection may return. If you experience severe side effects such as skin thinning, severe irritation, or signs of an allergic reaction, stop using the cream and consult your doctor immediately. Do not use it for longer than prescribed without medical review.
📅 Long-Term Use Effects
Long-term use of this medicine, especially over large areas or with occlusive dressings, can lead to skin thinning, stretch marks, visible blood vessels, and changes in skin color. It can also increase the risk of systemic steroid effects such as adrenal suppression, high blood sugar, and Cushing's syndrome-like features. To minimize these risks, use the smallest effective amount for the shortest duration. Your doctor may monitor your skin and, if necessary, your blood sugar and adrenal function during prolonged use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Proper hygiene helps prevent fungal growth and supports healing.
Evidence: Well-establishedFor mild fungal infections without significant inflammation, a plain antifungal cream may be sufficient.
Evidence: Well-establishedFor extensive or resistant infections, a doctor may prescribe oral antifungals.
Evidence: Well-establishedWearing loose cotton clothing, avoiding sharing personal items, and keeping skin dry can help prevent recurrence.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this topical cream and vaccines. You can receive vaccinations while using this medicine. However, if you have a severe skin infection or are unwell, consult your doctor about the timing of vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep the tube tightly closed
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription or doctor's note in case you need to show it at customs. Store the cream at room temperature and protect it from extreme heat or direct sunlight. If you are crossing time zones, continue applying the cream at your usual times; topical application does not require strict time-zone adjustment. Pack it in your carry-on luggage if you need it during the flight, but ensure it complies with liquid restrictions for creams.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Itching and redness may start to improve within a few days. Visible clearing of the fungal infection usually takes 1 to 2 weeks. If there is no improvement after 2 weeks, consult your doctor.
A: No, unless your doctor specifically tells you to. The face is more sensitive, and using steroids there can cause thinning, acne, or rosacea-like reactions.
A: Topical beclometasone and ketoconazole are generally considered low risk when used in small amounts for short periods, but you should only use this cream if prescribed by your doctor during pregnancy.
A: No, you should complete the full course prescribed by your doctor, even if symptoms improve early. Stopping too soon can allow the infection to return.
A: If a small amount is swallowed, it is unlikely to cause serious harm. If a large amount is swallowed, seek medical attention immediately.
🤔 Common Patient Concerns
🔄 Substitutes for keto-b cream
View AllAlternative brands with exact same active ingredient:
-
dikart-bn creamCure Tech Skincare ₹73.13 63% CHEAPER
-
salisia b creamAjanta Pharma Ltd ₹74.06 62.6% CHEAPER
-
allyzole-b creamMDC Pharmaceuticals Pvt Ltd ₹75.00 62.1% CHEAPER
-
Nizowal-BN Plus CreamWallace Pharmaceuticals Pvt Ltd ₹83.44 57.8% CHEAPER
-
knozole-b creamBest Biotech ₹85.00 57% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This cream is only for fungal skin infections with inflammation. Using it for other rashes can worsen the condition. - Myth: More cream means faster healing.
Fact: Applying more than a thin layer does not speed up healing and can increase the risk of side effects. - Myth: It is safe to use this cream for months.
Fact: Prolonged use can cause skin thinning and other steroid side effects. Use only as long as prescribed. - Myth: This cream can be used on the face for any rash.
Fact: It should not be used on the face unless specifically prescribed by a doctor, as facial skin is more sensitive.
🔄 Alternative Options
Generic Alternatives
- Beclometasone + Ketoconazole cream (generic versions may be available)