Aneket 100 mg Injection (Ketamine): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe respiratory depression or apnea
- Chest pain or palpitations
- Severe hypertension
- Signs of an allergic reaction (rash, swelling, difficulty breathing)
- Emergence delirium with severe agitation
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is ketmin 100mg injection used for?
This medicine is a dissociative anesthetic used for induction and maintenance of general anesthesia, procedural sedation, and off-label for treatment-resistant depression. It works by blocking NMDA receptors in the brain.
- Generic Name: Ketamine (100mg)
- Manufacturer: Themis Medicare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketmin 100mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से एनेस्थीसिया (बेहोशी) के लिए उपयोग की जाती है, खासकर आपातकालीन सर्जरी और उन प्रक्रियाओं में जहां मरीज का रक्तचाप स्थिर रखना आवश्यक होता है। यह दर्द निवारक और स्मृति-नाशक प्रभाव भी प्रदान करती है। इसका उपयोग अवसाद (डिप्रेशन) के इलाज में भी ऑफ-लेबल किया जाता है। यह केवल प्रशिक्षित डॉक्टर द्वारा अस्पताल में ही दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतिभ्रम, भ्रम, उत्तेजना और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में श्वसन अवसाद, लैरिंगोस्पाज्म और इंट्राक्रैनियल प्रेशर में वृद्धि हो सकती है। दुर्लभ मामलों में एलर्जी प्रतिक्रिया हो सकती है।
सुरक्षा सलाह: यह दवा केवल योग्य एनेस्थेसियोलॉजिस्ट या प्रशिक्षित स्वास्थ्यकर्मी द्वारा अस्पताल में ही दी जानी चाहिए। इस दवा को लेने के बाद कम से कम 24 घंटे तक वाहन न चलाएं और मशीनरी संचालित न करें। शराब और अन्य केंद्रीय तंत्रिका तंत्र अवसादकों से बचें। अपने डॉक्टर को उच्च रक्तचाप, हृदय रोग, मानसिक विकार या नशीली दवाओं के सेवन का इतिहास बताएं।
💊 ketmin 100mg injection Uses & Benefits
[{"condition":"Induction and maintenance of general anesthesia","description":"Used for the induction and maintenance of anesthesia, especially in patients with hemodynamic instability or those undergoing short procedures.","evidence":"Well-established"},{"condition":"Emergency surgery and field anesthesia","description":"Employed in emergency situations and field hospitals due to its ability to maintain spontaneous respiration and provide analgesia.","evidence":"Well-established"},{"condition":"Procedural sedation and analgesia","description":"Used for sedation and analgesia during painful procedures such as dressing changes, fracture reduction, and minor surgeries.","evidence":"Well-established"},{"condition":"Treatment-resistant depression","description":"Administered off-label as a rapid-acting antidepressant in treatment-resistant depression, often in subanesthetic doses.","evidence":"Emerging"},{"condition":"Chronic pain management","description":"Used off-label for complex regional pain syndrome and other chronic pain conditions, often in combination with other analgesics.","evidence":"Limited"}]
Off-label uses: [{"condition":"Treatment-resistant depression","description":"Subanesthetic doses of ketamine have shown rapid antidepressant effects in some patients with treatment-resistant depression.","evidence":"Emerging"},{"condition":"Complex regional pain syndrome","description":"Ketamine infusions may be used for refractory complex regional pain syndrome, though evidence is limited.","evidence":"Limited"},{"condition":"Status asthmaticus","description":"Ketamine has been used as a bronchodilator in severe asthma exacerbations, but this is not a standard use.","evidence":"Limited"}]
Primary treatment for: Anesthesia
Also treats: Treatment-resistant depression, Chronic pain
📋 Drug Information
| Generic Name(s) | Ketamine (100mg) |
| Brand Name | ketmin 100mg injection |
| Manufacturer | Themis Medicare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | General anaesthetic agents |
| Route of Administration | Parenteral (intravenous or intramuscular) |
| Storage | Store at room temperature (15-30°C). Protect from light. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine acts primarily as a non-competitive antagonist of the NMDA receptor complex. By binding to the phencyclidine site on the NMDA receptor, it blocks the excitatory effects of glutamate, leading to dissociation between the thalamocortical and limbic systems. This results in a trance-like state with profound analgesia, amnesia, and sedation, while maintaining cardiovascular stability and spontaneous breathing. It also interacts with opioid receptors, monoaminergic receptors, and voltage-gated calcium channels, contributing to its analgesic and psychotomimetic effects.
Mechanism Steps
💡 How to Take ketmin 100mg injection
Strength: 100 mg injection
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on indication, age, weight, and clinical status. For induction of anesthesia, a typical intravenous dose is 1-2 mg/kg, while intramuscular doses range from 4-10 mg/kg. For procedural sedation, lower doses (0.5-1 mg/kg IV) may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower doses due to increased sensitivity. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established from available information. Use with caution in severe renal impairment. |
| Hepatic Impairment | Dose reduction may be necessary in severe hepatic impairment. Consult a clinician. |
| Maximum Daily Dose | Not established from the available information. Dosing is individualized by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketmin 100mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Benzodiazepines | Major | |
| Opioids | Major | |
| Epinephrine | Major | |
| Antihypertensives | Moderate | |
| Theophylline | Moderate |
🚨 Major Interactions
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Sympathomimetics (e.g., epinephrine, norepinephrine)
- Thyroid hormones
⚡ Moderate Interactions
- Antihypertensives
- Theophylline
🍷 Alcohol Interaction
Alcohol increases the central nervous system depressant effects of this medicine and may exacerbate psychomotor impairment. Avoid alcohol for at least 24 hours after administration.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ketamine","Uncontrolled hypertension","Increased intracranial pressure","Aneurysms","Thyrotoxicosis","History of psychosis"]
⚠️ Warnings & Precautions
["Administer only by trained personnel in a monitored setting.","May cause emergence delirium; minimize stimulation during recovery.","Use with caution in patients with cardiovascular disease.","May increase intraocular pressure; caution in glaucoma.","Potential for abuse and dependence.","Avoid in patients with a history of substance abuse."]
🤱 Lactation Safety
Not established from the available information. Caution is advised; consult a healthcare provider before use in breastfeeding mothers.
💊 Overdose Management
Overdose may cause severe respiratory depression, apnea, and cardiovascular collapse. Management includes supportive care, assisted ventilation, and monitoring. There is no specific antidote. Contact emergency services immediately.
⏰ Missed Dose
This medicine is administered by a healthcare professional in a controlled setting. Missed doses are not applicable for self-administration.
Additional Safety Advice
This medicine must be administered only by a qualified anesthesiologist or trained healthcare provider in a hospital or surgical setting. Continuous monitoring of heart rate, blood pressure, oxygen saturation, and respiratory status is essential. Patients should inform their doctor about any history of hypertension, heart disease, psychiatric disorders, or substance abuse. Do not drive or operate machinery for at least 24 hours after receiving this medicine. Avoid alcohol and other central nervous system depressants during this period.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Lower doses and close monitoring are recommended.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. This medicine should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
After surgery, you will be monitored in a recovery area. Report any unusual symptoms to the medical staff. Do not drive or operate machinery for 24 hours.
🦷 Dental Procedures
This medicine may be used for sedation during dental procedures in a hospital setting. Inform your dentist if you have received this medicine recently.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise for at least 24 hours after receiving this medicine, as it may cause dizziness and impair coordination.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can impair mental alertness and physical coordination. Do not drive, operate machinery, or make important decisions for at least 24 hours after administration.
🛑 When to Stop This Medicine
This medicine is given as a single dose or short course by a healthcare professional. Do not self-administer. If you experience severe side effects, inform your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended outside of supervised medical settings due to potential for abuse, cognitive impairment, and urinary tract symptoms. Chronic use can lead to cystitis and kidney damage. Regular monitoring is required if used for chronic pain or depression.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another anesthetic agent with different side effect profile.
Evidence: Well-establishedUsed for induction of anesthesia, especially in hemodynamically unstable patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if solution is discolored or contains particles
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer to unmarked containers
✈️ Traveling with This Medicine
This medicine is administered in a hospital setting and is not for self-administration. If you are traveling after receiving this medicine, ensure you are accompanied by a responsible adult for at least 24 hours. Carry a copy of your prescription and medical records. Do not drive or operate machinery. Store any remaining medication as directed by your healthcare provider.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine works within 30 seconds after intravenous injection and within 3-5 minutes after intramuscular injection.
A: This medicine produces a dissociative state, so you may appear awake but will not feel pain or remember the procedure.
A: Common side effects include hallucinations, vivid dreams, confusion, and elevated blood pressure.
🤔 Common Patient Concerns
🔄 Substitutes for ketmin 100mg injection
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Ketamine is only used as a recreational drug.
Fact: Ketamine is a legitimate medical anesthetic used in hospitals and emergency settings. - Myth: Ketamine is safe for anyone to use.
Fact: Ketamine must be administered by trained professionals due to its potent effects and potential for serious side effects.
🔄 Alternative Options
Generic Alternatives
- Ketamine hydrochloride injection
Brand Alternatives
- Aneket 100 mg injection