Nodosis Tablet (Sodium Bicarbonate 500mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain or pressure that may radiate to the arm or jaw
- Difficulty breathing or shortness of breath
- Swelling of the face, lips, tongue, or throat
- Blood in vomit or black, tarry stools
- Severe abdominal pain that does not go away
- Confusion, muscle twitching, or irregular heartbeat
- Decreased urine output or swelling of the legs
If experiencing severe symptoms, call emergency services immediately.
What is kesod 500mg tablet used for?
This medicine contains Sodium Bicarbonate 500mg, an antacid that neutralizes stomach acid to provide fast relief from heartburn and indigestion. It is for short-term use only and should be avoided by people with high blood pressure, heart failure, or kidney disease.
- Generic Name: Sodium Bicarbonate (500mg)
- Manufacturer: Chemo Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kesod 500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सोडियम बाइकार्बोनेट 500mg युक्त है और मुख्य रूप से सीने में जलन, एसिडिटी और खट्टी डकार से राहत के लिए उपयोग की जाती है। यह पेट के एसिड को तुरंत बेअसर करती है। कुछ मामलों में डॉक्टर इसे मेटाबॉलिक एसिडोसिस या यूरिन को क्षारीय बनाने के लिए भी देते हैं। यह दवा केवल अल्पकालिक उपयोग के लिए है। उच्च रक्तचाप, हृदय रोग, गुर्दे की बीमारी या नमक-प्रतिबंधित आहार लेने वाले लोगों को इसका सेवन डॉक्टर की सलाह के बिना नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में डकार, पेट में गैस और हल्की असुविधा शामिल हैं। कभी-कभी प्यास लगना और बार-बार पेशाब आना भी हो सकता है। अधिक मात्रा में या लंबे समय तक सेवन से शरीर में सोडियम और बाइकार्बोनेट का स्तर बढ़ सकता है, जिससे सूजन, उच्च रक्तचाप, कमजोरी, मांसपेशियों में ऐंठन और अनियमित धड़कन जैसी गंभीर समस्याएं हो सकती हैं। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का सेवन डॉक्टर के निर्देशानुसार या लेबल पर लिखे अनुसार ही करें। एसिडिटी के लिए इसे दो सप्ताह से अधिक न लें। उच्च रक्तचाप, हृदय रोग, गुर्दे की बीमारी या कम नमक वाले आहार पर हैं तो इसका सेवन न करें। पर्याप्त पानी पिएं। गर्भवती और स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। एक्सपायरी डेट के बाद उपयोग न करें।
💊 kesod 500mg tablet Uses & Benefits
[{"condition":"Heartburn and acid indigestion","description":"Provides rapid but short-lasting relief by neutralizing stomach acid.","evidence":"Well-established"},{"condition":"Metabolic acidosis","description":"Used under medical supervision to correct acidosis in specific clinical settings.","evidence":"Established in specific clinical settings"},{"condition":"Urinary alkalinization","description":"Helps make urine less acidic, which can be useful in certain kidney stone or drug toxicity situations.","evidence":"Established for specific indications"},{"condition":"Sour stomach and dyspepsia","description":"Relieves mild stomach upset associated with excess acid.","evidence":"Well-established for short-term use"}]
Off-label uses: [{"condition":"Mouth rinse for oral hygiene","description":"Sometimes used as a homemade mouth rinse, but this is not a standard medical use.","evidence":"Limited"},{"condition":"Athletic performance enhancement","description":"Ergogenic aid claims exist, but evidence is not robust and safety is not established.","evidence":"Insufficient"}]
Primary treatment for: Heartburn and acid indigestion
Also treats: Metabolic acidosis, Urinary alkalinization, Dyspepsia
📋 Drug Information
| Generic Name(s) | Sodium Bicarbonate (500mg) |
| Brand Name | kesod 500mg tablet |
| Manufacturer | Chemo Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antacids |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by directly neutralizing excess hydrochloric acid in the stomach, forming sodium chloride, water, and carbon dioxide. The carbon dioxide produced causes belching. When absorbed systemically, bicarbonate ions act as a buffer to increase blood pH and can also alkalinize urine by increasing bicarbonate excretion. This helps correct metabolic acidosis and can alter the excretion of certain drugs and toxins.
Mechanism Steps
💡 How to Take kesod 500mg tablet
Strength: Tablet, 500 mg
Dosage Information
| Adult Dosage | The usual adult dose for heartburn and acid indigestion is 300 mg to 600 mg (or as directed on the label) taken as needed, up to four times a day. For systemic alkalinization, doses are individualized by a qualified clinician based on the condition, blood pH, and electrolyte levels. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of sodium bicarbonate, especially regarding fluid retention and electrolyte imbalances. Use with caution and under medical supervision. |
| Renal Impairment | Dose adjustment is required in renal impairment. Avoid use in severe kidney disease unless directed by a nephrologist. Monitor renal function and electrolytes closely. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and monitor for electrolyte imbalances. |
| Maximum Daily Dose | The maximum daily dose for self-medication should not exceed 1200 mg to 1800 mg per day, but this depends on the product and indication. Follow the label or doctor's advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kesod 500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Furosemide | Major | |
| Lithium | Moderate | |
| Aspirin | Moderate | |
| Tetracycline | Moderate | |
| Ketoconazole | Minor | |
| Iron supplements | Minor | |
| Corticosteroids | Major | |
| Calcium carbonate | Major | |
| Hydrochlorothiazide | Major | |
| Methenamine | Moderate |
🚨 Major Interactions
- Antacids containing calcium or magnesium
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Corticosteroids
⚡ Moderate Interactions
- Lithium
- Aspirin
- Tetracycline antibiotics
🍷 Alcohol Interaction
Alcohol can increase stomach acid and may worsen the condition being treated. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to sodium bicarbonate or any component","Severe kidney disease or kidney failure","Heart failure or uncontrolled high blood pressure","Metabolic or respiratory alkalosis","Hypocalcemia","Sodium-restricted diet","Hypernatremia"]
⚠️ Warnings & Precautions
["Do not use for more than 2 weeks without medical advice.","Avoid in patients with high blood pressure, heart disease, or kidney disease.","May cause sodium and fluid retention.","Can mask symptoms of more serious conditions like heart attack or ulcer.","Do not use if you have a history of kidney stones without consulting a doctor.","Not recommended for children under 12 years without medical advice.","Pregnant and breastfeeding women should consult a doctor before use."]
🤱 Lactation Safety
Sodium bicarbonate is excreted in breast milk, but the amounts are generally considered safe. However, consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose can cause severe metabolic alkalosis, hypernatremia, and hypokalemia. Symptoms include nausea, vomiting, confusion, muscle twitching, and irregular heartbeat. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids and electrolyte correction.
⏰ Missed Dose
This medicine is usually taken as needed for symptom relief. If you are on a scheduled regimen and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as directed by your doctor or as written on the label. Do not take it for more than two weeks for indigestion unless your doctor advises otherwise. Avoid using this medicine if you have high blood pressure, heart failure, kidney problems, or are on a low-sodium diet. Do not take it with other antacids or calcium supplements without consulting your doctor. Drink plenty of water while taking this medicine to help prevent constipation and kidney stones. If you are pregnant or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Do not use it after the expiry date. If symptoms persist or worsen, stop using it and consult a doctor. Do not use this medicine to treat a suspected heart attack or persistent chest pain.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to electrolyte imbalances and fluid retention. Use with caution and monitor blood pressure, kidney function, and electrolytes regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning pregnancy. It is generally not recommended for regular use during pregnancy without medical advice.
🏥 Post-Surgery Considerations
Consult your surgeon before using this medicine after surgery, as it may affect electrolyte balance and interact with other medications.
🦷 Dental Procedures
No specific precautions for dental procedures. Inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions are needed while taking this medicine. However, if you experience dizziness or weakness due to electrolyte imbalance, avoid strenuous exercise and consult a doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to drive or operate machinery. However, if you feel dizzy or unwell, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if symptoms persist beyond two weeks, if you experience side effects like swelling or irregular heartbeat, or if you need it more frequently than directed.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to metabolic alkalosis, electrolyte imbalances, kidney stones, and worsening of heart or kidney disease. It should only be used short-term unless under close medical supervision with regular monitoring of blood electrolytes and kidney function.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods can reduce heartburn episodes.
Evidence: Well-establishedWeight loss, smoking cessation, and elevating the head of the bed can help.
Evidence: Well-establishedCalcium carbonate or magnesium hydroxide may be alternatives, but consult a doctor.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. You can receive vaccines while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription if applicable. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, take it as needed for symptoms; no strict schedule adjustment is needed for as-needed use. Declare it at customs if required. Keep it in your carry-on luggage to avoid loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within minutes after taking it.
A: It is not recommended for daily long-term use without medical supervision. Consult your doctor if you need it frequently.
A: It can raise sodium levels and blood pressure. Avoid unless your doctor approves.
A: Do not combine with other antacids unless directed by a doctor, as it may cause excessive alkalosis.
🤔 Common Patient Concerns
🔄 Substitutes for kesod 500mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia sodium bicarbonate 500mg tabletDavaindia Generic Pharmacy ₹16.50 46.7% CHEAPER
-
sodarise 500mg tabletCarise Pharmaceuticals Pvt Ltd ₹25.31 18.2% CHEAPER
-
sodamax 500mg tabletSri Biotech Pvt Ltd ₹25.78 16.7% CHEAPER
-
F Biso 500mg TabletRidhima Biocare ₹26.16 15.4% CHEAPER
-
nabico 500mg tabletKlarvoyant Biogenics Pvt Ltd ₹28.13 9.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Sodium bicarbonate is a safe long-term treatment for acid reflux.
Fact: It is only for short-term relief. Long-term use can cause serious electrolyte imbalances. - Myth: It can be taken by anyone without any risk.
Fact: People with heart, kidney, or blood pressure problems should avoid it unless prescribed.
🔄 Alternative Options
Generic Alternatives
- Sodium Bicarbonate 500mg tablet
Brand Alternatives
- Nodosis Tablet