Kabiroc 10mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or oxygen desaturation
- Severe hypotension or cardiac arrest
- Signs of anaphylaxis such as rash, swelling, or wheezing
- Prolonged muscle paralysis beyond expected duration
- Unexplained fever or muscle rigidity (possible malignant hyperthermia)
- Injection site pain or swelling
If experiencing severe symptoms, call emergency services immediately.
What is kabiroc 10mg injection used for?
This medicine is a muscle relaxant used during surgery and mechanical ventilation. It is given intravenously by a healthcare professional and works by blocking nerve signals to muscles, causing temporary paralysis.
- Generic Name: Rocuronium (10mg)
- Manufacturer: Fresenius Kabi India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kabiroc 10mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा रोक्यूरोनियम नामक एक मांसपेशी शिथिलक है, जिसका उपयोग सामान्य एनेस्थीसिया के दौरान मांसपेशियों को ढीला करने और श्वास नली में ट्यूब डालने के लिए किया जाता है। यह केवल अस्पताल में प्रशिक्षित डॉक्टर द्वारा नस में इंजेक्शन के रूप में दी जाती है। यह दर्द निवारक या बुखार कम करने वाली दवा नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में रक्तचाप में कमी, चेहरे पर लालिमा और इंजेक्शन स्थल पर हल्की प्रतिक्रिया शामिल हैं। गंभीर दुष्प्रभावों में लंबे समय तक मांसपेशियों का पक्षाघात, सांस की कमी और एनाफिलेक्सिस हो सकते हैं। इनका तुरंत इलाज जरूरी है।
सुरक्षा सलाह: यह दवा केवल अस्पताल में विशेषज्ञ डॉक्टर द्वारा दी जानी चाहिए। इस दवा को देने से पहले और बाद में मरीज की सांस, हृदय गति और रक्तचाप की निगरानी जरूरी है। एलर्जी या अन्य बीमारियों की जानकारी डॉक्टर को दें।
💊 kabiroc 10mg injection Uses & Benefits
[{"condition":"Endotracheal intubation","description":"Facilitates intubation during general anesthesia by relaxing the jaw and vocal cords.","evidence":"Well-established"},{"condition":"Skeletal muscle relaxation during surgery","description":"Provides muscle relaxation for abdominal, orthopedic, and other surgical procedures.","evidence":"Well-established"},{"condition":"Mechanical ventilation in ICU","description":"Used for short-term paralysis to improve ventilation and reduce patient-ventilator dyssynchrony.","evidence":"Well-established"},{"condition":"Rapid sequence intubation","description":"Used in emergency airway management when rapid paralysis is required.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Treatment of tetanus-induced muscle spasms","description":"Occasionally used to control severe muscle spasms in tetanus when other measures fail.","evidence":"Limited"},{"condition":"Adjunct in electroconvulsive therapy","description":"Used to modify convulsions during ECT in selected patients.","evidence":"Limited"}]
Primary treatment for: Not applicable; used for anesthesia and mechanical ventilation.
📋 Drug Information
| Generic Name(s) | Rocuronium (10mg) |
| Brand Name | kabiroc 10mg injection |
| Manufacturer | Fresenius Kabi India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Skeletal muscle relaxant- Peripherally acting |
| Route of Administration | Parenteral (intravenous) |
| Storage | Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Once opened, use immediately. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by competitively binding to nicotinic acetylcholine receptors at the motor endplate of the neuromuscular junction. By blocking acetylcholine from binding, it prevents depolarization of the muscle membrane, leading to flaccid paralysis. This action is non-depolarizing and reversible with acetylcholinesterase inhibitors such as neostigmine.
Mechanism Steps
💡 How to Take kabiroc 10mg injection
Strength: Injection: 10 mg/mL
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the procedure, patient weight, and clinical status. For endotracheal intubation, a common initial dose is 0.6 mg/kg intravenously, which provides muscle relaxation for approximately 30 to 60 minutes. For rapid sequence intubation, a higher dose of 1.0 to 1.2 mg/kg may be used. Maintenance doses of 0.1 to 0.2 mg/kg may be given as needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have prolonged duration of action. Doses should be individualized by a qualified clinician based on age, weight, and organ function. |
| Renal Impairment | Use with caution in renal impairment. Dose reduction may be necessary. Individualize by a qualified clinician. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose reduction may be necessary. Individualize by a qualified clinician. |
| Maximum Daily Dose | Not established from the available information. Dosing is individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kabiroc 10mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | |
| Magnesium sulfate | Major | |
| Inhaled anesthetics | Major | |
| Loop diuretics | Moderate | |
| Calcium channel blockers | Moderate | |
| Corticosteroids | Minor |
🚨 Major Interactions
- Aminoglycoside antibiotics
- Magnesium sulfate
- Inhaled anesthetics
⚡ Moderate Interactions
- Loop diuretics
- Calcium channel blockers
🍷 Alcohol Interaction
No direct interaction with alcohol is established, but alcohol may potentiate central nervous system depression. Avoid alcohol before and after anesthesia.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to rocuronium or other aminosteroid muscle relaxants","Known or suspected malignant hyperthermia","Inability to provide adequate ventilatory support"]
⚠️ Warnings & Precautions
["Administer only by experienced clinicians in a monitored setting.","Use with caution in patients with neuromuscular disorders.","May cause prolonged paralysis in hepatic or renal impairment.","Risk of anaphylaxis; be prepared for emergency treatment.","Avoid use in patients with known allergy to aminosteroids."]
🤱 Lactation Safety
Not established from the available information. It is not known if rocuronium is excreted in breast milk. Use with caution in breastfeeding mothers.
💊 Overdose Management
Overdose leads to prolonged muscle paralysis and respiratory depression. Maintain ventilation and oxygenation. Administer acetylcholinesterase inhibitors (e.g., neostigmine) with an anticholinergic (e.g., glycopyrrolate) for reversal. Continue monitoring until full recovery.
⏰ Missed Dose
This medicine is given only by healthcare professionals in controlled settings. Missed doses are not applicable.
Additional Safety Advice
This medicine must only be administered by trained healthcare professionals in a facility equipped for intubation, mechanical ventilation, and resuscitation. Continuous monitoring of neuromuscular function, heart rate, blood pressure, and oxygen saturation is mandatory. Do not use if the solution is discolored or contains particles. Ensure adequate reversal agents and emergency drugs are immediately available. Inform your care team of all medications, allergies, and medical conditions before receiving this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have a prolonged response. Doses should be adjusted by a qualified clinician.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are pregnant or planning pregnancy. Use only if clearly needed.
🏥 Post-Surgery Considerations
After surgery, you will be monitored until the effects of this medicine wear off. Follow your doctor's advice for recovery.
🦷 Dental Procedures
This medicine is not used in dental procedures unless performed under general anesthesia in a hospital setting.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting until your doctor clears you, as muscle strength may take time to fully return.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Do not drive or operate machinery for at least 24 hours after receiving this medicine. Wait until you are fully alert and your doctor approves.
🛑 When to Stop This Medicine
This medicine is stopped by the healthcare provider once the procedure is complete or when muscle relaxation is no longer needed. Do not attempt to stop or adjust it yourself.
📅 Long-Term Use Effects
Long-term effects are not established for single-dose use. Prolonged use in intensive care may lead to muscle weakness and prolonged paralysis. Monitoring and physical therapy may be needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Vecuronium or atracurium may be used depending on clinical needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. Inform your doctor about recent vaccinations before surgery.
📦 Storage Guide
✅ DO
Store refrigerated at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if discolored or contains particles
✅ DO
Keep in original container
❌ DON'T
Do not store at room temperature for long periods
✈️ Traveling with This Medicine
This medicine is administered only in healthcare facilities and is not for self-administration. Patients do not need to carry it during travel. If you are traveling after a procedure, carry a copy of your medical records and inform your doctor about any recent anesthesia.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 3 minutes after intravenous injection.
A: The effect typically lasts 30 to 60 minutes, depending on the dose and individual factors.
A: No, you will be monitored in a recovery area until the effects wear off completely.
🤔 Common Patient Concerns
🔄 Substitutes for kabiroc 10mg injection
View AllAlternative brands with exact same active ingredient:
-
Rocubro 10mg InjectionCachet Pharmaceuticals Pvt Ltd ₹285.94 17.1% CHEAPER
-
roger 10mg injectionZydus Cadila ₹301.43 12.6% CHEAPER
-
Rocutroy 10mg InjectionTroikaa Pharmaceuticals Ltd ₹375.00 8.7% COSTLIER
-
rocurofix injectionVarenyam Healthcare Pvt Ltd ₹590.63 71.2% COSTLIER
-
Rocurofix 100 InjectionVarenyam Healthcare Pvt Ltd ₹1,113.18 222.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for pain relief.
Fact: This medicine is a muscle relaxant used only during anesthesia; it does not relieve pain. - Myth: This medicine can be taken orally.
Fact: This medicine is given only intravenously in a hospital setting.
🔄 Alternative Options
Generic Alternatives
- Rocuronium bromide
Brand Alternatives
- Kabiroc 10mg injection