hospicasp 50mg Injection (Caspofungin): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or wheezing
- Severe rash, blistering, or peeling skin
- Yellowing of the eyes or skin
- Dark urine or severe tiredness
- Chest tightness or a sudden drop in blood pressure during infusion
- Seizures or loss of consciousness
- Blood in vomit or stool
If experiencing severe symptoms, call emergency services immediately.
What is kabifungin 50 injection used for?
This medicine is an intravenous antifungal containing caspofungin 50 mg. It is used to treat serious fungal infections such as invasive candidiasis, candidemia, and esophageal candidiasis. It works by breaking down the fungal cell wall. It is given only by a healthcare professional in a hospital or clinic setting.
- Generic Name: Caspofungin (50mg)
- Manufacturer: Fresenius Kabi India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kabifungin 50 injection के बारे में (Hindi Summary)
उपयोग: यह दवा कैस्पोफंजिन 50 मिलीग्राम इंजेक्शन है, जिसका उपयोग गंभीर फंगल संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से रक्त में फंगस (कैंडिडेमिया), गहरे ऊतकों में कैंडिडा संक्रमण, और अन्नप्रणाली के कैंडिडा संक्रमण के लिए दी जाती है। यह उन मरीजों में भी दी जा सकती है जिनका बुखार बना रहता है और सफेद रक्त कोशिकाओं की संख्या बहुत कम होती है। यह दवा फंगस की कोशिका भित्ति को तोड़कर उसे नष्ट करती है। यह केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है। इसे घर पर स्वयं नहीं लगाया जा सकता।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में बुखार, ठंड लगना, सिरदर्द, जी मिचलाना, उल्टी, दस्त, पेट दर्द और इंजेक्शन लगाने की जगह पर लालिमा या सूजन शामिल हैं। कुछ मरीजों में दिल की धड़कन तेज हो सकती है, रक्तचाप कम हो सकता है, या त्वचा पर चकत्ते पड़ सकते हैं। गंभीर लेकिन दुर्लभ दुष्प्रभावों में चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई, और अचानक रक्तचाप गिरना शामिल है। कभी-कभी लिवर एंजाइम बढ़ सकते हैं। इंजेक्शन के दौरान कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर या नर्स को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर साइक्लोस्पोरिन, टैक्रोलिमस, रिफैम्पिन, कार्बामाजेपिन, फेनिटोइन और डेक्सामेथासोन। इलाज के दौरान लिवर, किडनी और इलेक्ट्रोलाइट की जांच के लिए खून की जांच की आवश्यकता हो सकती है। गर्भवती महिलाएं या गर्भधारण की योजना बना रही महिलाएं डॉक्टर से सलाह लें। स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के यह दवा न लें। चेहरे या गले में सूजन, सांस लेने में तकलीफ, गंभीर चकत्ते, या आंखों-त्वचा का पीला पड़ना दिखे तो तुरंत आपातकालीन चिकित्सा सहायता लें।
💊 kabifungin 50 injection Uses & Benefits
[{"condition":"Invasive candidiasis and candidemia","description":"This medicine is used as first-line therapy for bloodstream and deep-tissue Candida infections in many hospital settings.","evidence":"Well-established"},{"condition":"Esophageal candidiasis","description":"It is used to treat Candida infection of the esophagus, especially when other antifungals are not suitable.","evidence":"Well-established"},{"condition":"Empirical therapy in febrile neutropenia","description":"It may be given to patients with persistent fever and low white blood cell counts when a fungal infection is suspected.","evidence":"Well-established"},{"condition":"Invasive aspergillosis (salvage therapy)","description":"It is sometimes used when standard therapy is not tolerated or not effective, often in combination with other antifungals.","evidence":"Moderate"},{"condition":"Intra-abdominal abscess and peritonitis due to Candida","description":"It may be used as part of treatment for Candida infections in the abdominal cavity.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Fungal endocarditis","description":"Rarely used as part of combination therapy for fungal infection of the heart valves.","evidence":"Limited"},{"condition":"Fungal osteomyelitis and septic arthritis","description":"Occasionally used for bone and joint fungal infections when other options are unsuitable.","evidence":"Limited"},{"condition":"Prophylaxis in high-risk transplant patients","description":"Sometimes considered for preventing fungal infections in certain very high-risk patients.","evidence":"Limited"}]
Primary treatment for: Invasive candidiasis
Also treats: Candidemia, Esophageal candidiasis, Febrile neutropenia with suspected fungal infection, Invasive aspergillosis (salvage therapy)
📋 Drug Information
| Generic Name(s) | Caspofungin (50mg) |
| Brand Name | kabifungin 50 injection |
| Manufacturer | Fresenius Kabi India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OTHERS |
| Action Class | Fungal cell wall synthesis inhibitor (Echiocandins) |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store this medicine in the refrigerator at 2°C to 8°C before reconstitution. After reconstitution, the solution may be stored at room temperature for a limited time as directed by the manufacturer. Protect from light and do not freeze. Follow the specific storage instructions provided with the product. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture when stored as directed. Check the expiry date on the vial before use. |
| WHO Guideline | Not established from the available information for this specific product. Treatment guidelines for invasive candidiasis generally include echinocandins as a first-line option, but the exact recommendation depends on the clinical setting and local resistance patterns. |
| ICMR Guideline | Not established from the available information for this specific product. Clinicians should refer to current national or institutional guidelines for the management of fungal infections. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine belongs to the echinocandin class and works by non-competitively inhibiting the enzyme beta-1,3-D-glucan synthase. This enzyme is responsible for making beta-1,3-D-glucan, a key structural polysaccharide in the fungal cell wall. When this medicine blocks the enzyme, the fungal cell wall becomes weak and cannot maintain its shape or pressure, leading to cell lysis and death. Because human cells do not have a cell wall or beta-1,3-D-glucan, this medicine has a selective action against susceptible fungi with less effect on human cells. It is active against many Candida species, including those that are resistant to azole antifungals, and against Aspergillus species, although it is not fully fungicidal against Aspergillus.
Mechanism Steps
💡 How to Take kabifungin 50 injection
Strength: 50 mg lyophilized powder for intravenous infusion
Dosage Information
| Adult Dosage | The usual adult dose of this medicine depends on the type and severity of the fungal infection. A common regimen starts with a loading dose of 70 mg on day one, followed by 50 mg once daily thereafter. For esophageal candidiasis, a dose of 50 mg once daily is often used. For patients with moderate liver impairment, a lower maintenance dose may be recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, liver function, kidney function, and other medicines being taken. This medicine is given by intravenous infusion over approximately one hour. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific product. Consult a pediatrician or pediatric infectious disease specialist for dosing in children. |
| Elderly Dosage | Elderly patients usually receive the same dose as younger adults, but they may be more sensitive to side effects. Kidney and liver function should be checked before and during treatment. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment is not usually required for kidney impairment alone. However, kidney function should be monitored, and the dose may need to be reviewed if kidney function changes significantly during treatment. |
| Hepatic Impairment | For adults with moderate liver impairment, a reduced maintenance dose of 35 mg once daily may be recommended after the initial loading dose. For severe liver impairment, the medicine should be used with caution and the dose should be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is generally 70 mg for the loading dose on day one and 50 mg for maintenance, but higher doses may be used in certain situations under specialist supervision. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kabifungin 50 injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cyclosporine | Major | |
| Rifampin | Major | |
| Tacrolimus | Moderate | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Dexamethasone | Moderate | |
| Mycophenolate mofetil | Minor |
🚨 Major Interactions
- Cyclosporine
- Rifampin
⚡ Moderate Interactions
- Tacrolimus
- Carbamazepine, phenytoin, dexamethasone, or other enzyme inducers
🍷 Alcohol Interaction
Alcohol is not known to interact directly with this medicine, but drinking alcohol may worsen liver stress and dehydration during a serious infection. It is best to avoid alcohol while you are being treated for a serious fungal infection and until your doctor says it is safe.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known serious allergy to caspofungin or any other echinocandin antifungal","Known serious allergy to any ingredient in this medicine"]
⚠️ Warnings & Precautions
["This medicine must be given by a healthcare professional in a monitored setting.","Tell your doctor if you have liver disease, as a lower dose may be needed.","Tell your doctor about all other medicines you take, especially cyclosporine, rifampin, tacrolimus, carbamazepine, phenytoin, or dexamethasone.","Infusion-related reactions can occur; report flushing, itching, chest tightness, or difficulty breathing during the infusion.","Blood tests may be needed to monitor liver enzymes, kidney function, and electrolytes.","Do not breastfeed while receiving this medicine without medical advice.","Use during pregnancy only if clearly needed and after discussing risks with your doctor."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because many medicines can pass into breast milk, breastfeeding is not recommended while receiving this medicine unless the doctor advises otherwise.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by healthcare professionals. If too much is given, treatment should be supportive and directed at relieving symptoms. There is no specific antidote. Monitor vital signs, liver function, kidney function, and electrolytes closely. Contact a poison control center or emergency department for guidance if an overdose is suspected.
⏰ Missed Dose
Because this medicine is given by a healthcare professional in a hospital or clinic, a missed dose is unlikely. If a scheduled dose is missed, contact your doctor or nurse as soon as possible. Do not try to make up for a missed dose by taking extra medicine. The healthcare team will decide when the next dose should be given.
Additional Safety Advice
This medicine must be given only by a trained healthcare professional in a setting where emergency equipment is available. Tell your doctor about all medicines you take, especially cyclosporine, tacrolimus, rifampin, carbamazepine, phenytoin, dexamethasone, or other drugs that affect the liver. Blood tests to check liver enzymes, kidney function, and electrolyte levels may be needed before and during treatment. Do not breastfeed while receiving this medicine without discussing it with your doctor. If you are pregnant or planning pregnancy, inform your doctor so the risks and benefits can be weighed. Do not attempt to use this medicine at home or self-administer it. Keep all follow-up appointments so your response to treatment can be monitored. If you notice swelling of the face or throat, trouble breathing, a severe rash, or yellowing of the eyes or skin, seek emergency medical help right away.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients usually receive the same dose as younger adults, but they may be more sensitive to side effects such as liver enzyme changes and electrolyte imbalances. Kidney and liver function should be checked before and during treatment. Falls and dehydration should be avoided, and any new symptoms should be reported promptly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this with your doctor before starting or continuing this medicine. It should be used during pregnancy only when clearly needed. Effective contraception may be advised during treatment. If you become pregnant while receiving this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
This medicine may be used after surgery if a fungal infection is suspected or confirmed. It does not interfere with wound healing directly, but it is important to monitor for signs of infection and to follow your surgeon's instructions. Inform your surgical team that you are receiving this medicine.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine before any dental procedure. There is no specific contraindication to dental work, but your dentist may want to coordinate with your doctor, especially if you have a weakened immune system or are taking other medicines.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine for a serious infection, strenuous exercise is usually not recommended until you have recovered. Light activity such as short walks may be allowed if you feel well enough. Always follow your doctor's advice about activity levels, especially if you have low blood pressure, fever, or fatigue.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you may need time off work during treatment. You may feel tired, nauseated, or have fever and chills after infusions. Avoid driving or operating heavy machinery if you feel dizzy, weak, or unwell. Discuss your work schedule with your doctor and employer so you can attend infusions and follow-up appointments.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. The decision to stop is made by your doctor based on your clinical response, blood tests, and the type of infection. If you develop serious side effects such as a severe allergic reaction, liver problems, or severe infusion reactions, your doctor may stop the medicine or switch to another treatment. Always consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is uncommon because it is usually given for a defined course to treat a specific infection. Prolonged therapy may increase the risk of liver enzyme elevations and electrolyte imbalances. Regular blood tests are needed to monitor liver function, kidney function, and electrolyte levels. If long-term treatment is required, your doctor will review the benefits and risks periodically and may adjust the dose or switch to another antifungal if needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
These are similar antifungals that may be used if this medicine is not suitable.
Evidence: Well-establishedThese may be used for less severe infections or after initial control with an echinocandin.
Evidence: Well-establishedThese are older antifungals used for serious fungal infections when other options are not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, because it is used in patients with serious infections and sometimes weakened immune systems, live vaccines should generally be avoided during treatment. Discuss any vaccination plans with your doctor.
📦 Storage Guide
✅ DO
Store the vial in the refrigerator at 2°C to 8°C before reconstitution.
❌ DON'T
Do not freeze the vial.
✅ DO
Keep the vial in its original carton to protect it from light.
❌ DON'T
Do not store it at room temperature for long periods before reconstitution.
✅ DO
Use the reconstituted solution within the time recommended by the manufacturer.
❌ DON'T
Do not use the solution if it is cloudy or contains particles.
✈️ Traveling with This Medicine
This medicine is given in a hospital or clinic, so travel planning should be discussed with your treating doctor. If you need to travel during treatment, carry a copy of your prescription and medical records. The medicine is stored in a refrigerator before use, so it must be transported under proper cold-chain conditions by a healthcare professional. Do not carry reconstituted solution without medical guidance. Inform airport security about any medical documentation if you are carrying prescribed medicines. Plan your travel around your infusion schedule so that doses are not missed.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some improvement may be seen within a few days, but the full course may take one to several weeks depending on the type and severity of the infection. Your doctor will monitor your response.
A: No. This medicine is given intravenously by a healthcare professional in a hospital or clinic setting where monitoring is available.
A: Because this medicine is given by healthcare professionals, missed doses are managed by your medical team. Inform your nurse or doctor if a dose is delayed.
A: It should be used during pregnancy only when the potential benefit justifies the potential risk. Discuss with your doctor if you are pregnant or planning pregnancy.
A: It is not directly harmful to the kidneys in most patients, but kidney function may be monitored during treatment, especially if you have other risk factors.
🤔 Common Patient Concerns
🔄 Substitutes for kabifungin 50 injection
View AllAlternative brands with exact same active ingredient:
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casfung 50mg injectionGlenmark Pharmaceuticals Ltd ₹3,999.00 75.4% CHEAPER
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capsain 50mg injectionSun Pharmaceutical Industries Ltd ₹7,980.00 50.9% CHEAPER
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hospicasp 50mg injectionAlkem Laboratories Ltd ₹7,999.00 50.7% CHEAPER
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canducid 50 injectionZyphar's Pharmaceuticals Pvt Ltd ₹8,125.60 50% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home like an antibiotic tablet.
Fact: This medicine is an intravenous antifungal that must be given by a healthcare professional in a monitored setting. - Myth: This medicine works against all types of infections.
Fact: This medicine only works against certain fungal infections. It does not treat bacterial or viral infections. - Myth: You can stop the medicine as soon as you feel better.
Fact: The full course must be completed as advised by your doctor to prevent the infection from returning.
🔄 Alternative Options
Generic Alternatives
- Caspofungin 50 mg injection
Brand Alternatives
- hospicasp 50mg injection