Durnox TH 8mg/4mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe dizziness or fainting
- Persistent fever or sore throat
If experiencing severe symptoms, call emergency services immediately.
What is jornox-t4 tablet used for?
This medicine is a combination of Lornoxicam (an NSAID) and Thiocolchicoside (a muscle relaxant) used for short-term relief of acute musculoskeletal pain and muscle spasm. It works by reducing inflammation and relaxing muscles. Take it with food, avoid alcohol, and do not use for longer than prescribed.
- Generic Name: Lornoxicam (8mg) + Thiocolchicoside (4mg)
- Manufacturer: Morecare Pharmatec Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jornox-t4 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लॉर्नोक्सिकैम और थायोकोलचिकोसाइड का संयोजन है, जिसका उपयोग मांसपेशियों में ऐंठन और दर्द के इलाज के लिए किया जाता है। यह दवा मांसपेशियों को आराम देती है और सूजन को कम करती है। यह आमतौर पर कमर दर्द, गर्दन दर्द, और चोट के बाद होने वाले दर्द में राहत के लिए दी जाती है। इसका उपयोग केवल थोड़े समय के लिए करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन पेट में रक्तस्राव, गुर्दे की समस्या, या एलर्जी हो सकती है। यदि आपको काला मल, खून की उल्टी, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग न करें।
💊 jornox-t4 tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain with muscle spasm","description":"Relieves pain and reduces muscle spasm in conditions such as low back pain, neck pain, and myofascial pain syndrome.","evidence":"Well-established"},{"condition":"Post-operative pain and inflammation","description":"Used short-term to manage pain and swelling after surgical procedures involving muscles or joints.","evidence":"Moderate"},{"condition":"Post-traumatic pain","description":"Helps reduce pain and muscle spasm following injuries such as sprains, strains, and fractures.","evidence":"Moderate"},{"condition":"Osteoarthritis flare-ups","description":"Provides short-term relief of pain and stiffness during acute exacerbations of osteoarthritis.","evidence":"Limited"},{"condition":"Rheumatoid arthritis","description":"May be used short-term for symptomatic relief of pain and inflammation in rheumatoid arthritis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes prescribed off-label for tension headaches associated with muscle tightness.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for painful menstrual cramps, though not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Myofascial pain syndrome, Post-operative pain, Post-traumatic pain, Osteoarthritis flare-ups
📋 Drug Information
| Generic Name(s) | Lornoxicam (8mg) + Thiocolchicoside (4mg) |
| Brand Name | jornox-t4 tablet |
| Manufacturer | Morecare Pharmatec Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Lornoxicam is a non-steroidal anti-inflammatory drug that reversibly inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, thereby reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This leads to analgesic, anti-inflammatory, and antipyretic effects. Thiocolchicoside is a centrally acting muscle relaxant that binds to GABA-A receptors in the spinal cord and brainstem, enhancing GABAergic inhibition and reducing excessive muscle tone. Together, they provide relief from pain and muscle spasm.
Mechanism Steps
💡 How to Take jornox-t4 tablet
Strength: Each tablet contains Lornoxicam 8 mg and Thiocolchicoside 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to three times daily, preferably with food. The exact dose and duration depend on the condition being treated, its severity, and your response to therapy. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Use for the shortest duration necessary to control symptoms. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) are at increased risk of gastrointestinal, kidney, and cardiovascular side effects. Use the lowest effective dose for the shortest duration possible. Monitor renal and hepatic function closely. Consult your doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with mild to moderate renal impairment. Dose reduction may be necessary. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). Consult your doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. Dose reduction may be necessary. This medicine is contraindicated in severe hepatic impairment. Consult your doctor for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (24 mg lornoxicam and 12 mg thiocolchicoside) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jornox-t4 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors/ARBs | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Beta-blockers | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, diclofenac)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors and ARBs
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- SSRIs (e.g., fluoxetine, sertraline)
- Beta-blockers
- Cyclosporine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage. It may also enhance the sedative effects of thiocolchicoside, leading to increased drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to lornoxicam, thiocolchicoside, or any other NSAID.","Active or history of recurrent peptic ulcer, gastrointestinal bleeding, or perforation.","Severe heart failure, severe hypertension, or recent myocardial infarction.","Severe liver impairment or active liver disease.","Severe kidney impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Take this medicine with food or milk to reduce gastrointestinal irritation.","Avoid alcohol consumption while taking this medicine.","Do not drive or operate heavy machinery if you experience dizziness or drowsiness.","Use the lowest effective dose for the shortest duration possible.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or bleeding disorders.","Do not take other NSAIDs or pain relievers without consulting your doctor.","If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine.","Elderly patients are at higher risk of side effects and should use with caution.","Monitor for signs of gastrointestinal bleeding, such as black or tarry stools, and report immediately.","This medicine may mask signs of infection; consult your doctor if you develop fever or other symptoms."]
🤱 Lactation Safety
Not established from the available information. It is not known whether lornoxicam and thiocolchicoside pass into breast milk. Due to the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, dizziness, and in severe cases, kidney or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be administered if the patient presents within 1-2 hours of ingestion. Monitor vital signs, renal and hepatic function, and manage complications accordingly.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Always take it with food or milk to reduce the risk of stomach upset. Avoid alcohol while taking this medicine because it can increase the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or bleeding disorders. Do not take other NSAIDs or pain relievers without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before taking this medicine. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at increased risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events with NSAIDs. Use the lowest effective dose for the shortest duration possible. Monitor renal and hepatic function closely. Avoid concurrent use with other NSAIDs or anticoagulants. Consult your doctor for appropriate dosing and monitoring.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like lornoxicam may affect ovulation and are not recommended during pregnancy, especially in the third trimester. Discuss alternative pain management options with your doctor.
🏥 Post-Surgery Considerations
This medicine may be prescribed for post-operative pain and muscle spasm. Take it exactly as directed by your surgeon. Inform your surgeon about all other medications you are taking. Monitor for signs of bleeding or infection. Do not use for prolonged periods without medical supervision.
🦷 Dental Procedures
If you are scheduled for dental work, inform your dentist that you are taking this medicine. It may increase the risk of bleeding during dental procedures. Your dentist may advise you to stop the medicine temporarily before the procedure. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercise or activities that may exacerbate muscle pain or spasm. Gentle stretching and low-impact exercises may be beneficial, but consult your doctor or physiotherapist before starting any exercise program. Stop immediately if you experience increased pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate heavy machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. If your work involves physical labor, consult your doctor about modifications. Generally, it should not significantly impact desk jobs, but caution is advised.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience any serious side effects, such as gastrointestinal bleeding, severe abdominal pain, allergic reactions, or signs of kidney or liver problems. Do not stop abruptly without consulting your doctor if you have been taking it for more than a few days. Your doctor will advise you on the appropriate duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the risk of serious side effects, including gastrointestinal bleeding, ulcers, kidney damage, liver damage, and increased cardiovascular risk. If long-term use is necessary, regular monitoring of liver and kidney function, complete blood count, and gastrointestinal symptoms is advised. Consult your doctor regularly to assess the need for continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and muscle spasm.
Evidence: Well-establishedApplying heat or cold packs can help relieve muscle spasm and pain.
Evidence: ModerateMay provide relief for certain types of musculoskeletal pain.
Evidence: LimitedGentle stretching and yoga can improve flexibility and reduce muscle tension.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor about all medications you are taking. This medicine may mask signs of infection, so consult your doctor if you have a fever or other symptoms before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually to avoid missed doses. Check local customs regulations regarding prescription medicines. Always carry enough supply for your trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking this medicine. Muscle relaxant effects may be noticeable within 1 to 2 hours.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: This medicine is not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. Consult your doctor for alternatives.
A: No, alcohol should be avoided as it increases the risk of gastrointestinal bleeding and liver damage.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for jornox-t4 tablet
View AllAlternative brands with exact same active ingredient:
-
lornoxi t4 tabletHetero Drugs Ltd ₹88.39 47% CHEAPER
-
xocam mr 8mg/4mg tabletArchis Healthcare ₹125.00 25.1% CHEAPER
-
lorsumo 8 mg/4 mg tablet mrAlkem Laboratories Ltd ₹131.25 21.4% CHEAPER
-
Thiocor 8mg/4mg TabletWaksman Selman Pharmaceuticals Pvt Ltd ₹135.94 18.5% CHEAPER
-
ostiflex mr tablet 8 mg/4 mgZydus Cadila ₹145.00 13.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of gastrointestinal, kidney, and liver problems. - Myth: It is safe to take this medicine on an empty stomach.
Fact: Taking this medicine with food reduces the risk of stomach upset and gastrointestinal irritation. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol should be avoided as it increases the risk of gastrointestinal bleeding and liver damage. - Myth: This medicine is a steroid.
Fact: This medicine contains an NSAID and a muscle relaxant, not a steroid.
🔄 Alternative Options
Generic Alternatives
- Lornoxicam + Thiocolchicoside
Brand Alternatives
- Durnox TH 8mg/4mg Tablet
- Lornoxi TH
- Thioflex