Antof LZ Oral Suspension: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Tendon pain or swelling
- Numbness or tingling in hands or feet
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is jestylox oz oral suspension used for?
This medicine is a combination antibiotic and antiprotozoal oral suspension containing levofloxacin and ornidazole. It is used to treat infections like amoebic dysentery, giardiasis, and mixed bacterial-protozoal diarrhea. It works by killing bacteria and parasites. It should be taken exactly as prescribed, and alcohol must be avoided.
- Generic Name: Levofloxacin (125mg/5ml) + Ornidazole (125mg/5ml)
- Manufacturer: Pritus Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jestylox oz oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोफ्लोक्सासिन और ओर्निडाजोल का संयोजन है, जिसका उपयोग आंतों के संक्रमण जैसे अमीबिक पेचिश, जिआर्डिया और मिश्रित बैक्टीरियल-प्रोटोज़ोअल दस्त के इलाज के लिए किया जाता है। यह बैक्टीरिया और परजीवियों को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें और शराब का सेवन बिल्कुल न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और मुँह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, दौरे, गंभीर एलर्जी और रक्त विकार हो सकते हैं। शराब के साथ लेने पर गंभीर प्रतिक्रिया हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक पूरी करें, बीच में न छोड़ें। उपयोग से पहले बोतल को अच्छी तरह हिलाएँ। मापने वाले कप या सिरिंज से ही खुराक लें। शराब का सेवन बिल्कुल न करें। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ 2 घंटे का अंतराल रखें। यदि चक्कर आए तो वाहन न चलाएँ। गुर्दे या जिगर की बीमारी हो तो डॉक्टर को बताएँ।
💊 jestylox oz oral suspension Uses & Benefits
[{"condition":"Amoebic dysentery","description":"This medicine is effective against Entamoeba histolytica, the parasite that causes amoebic dysentery, leading to relief from bloody diarrhea, abdominal pain, and fever.","evidence":"Well-established"},{"condition":"Giardiasis","description":"It treats Giardia lamblia infection, which causes prolonged diarrhea, bloating, and malabsorption.","evidence":"Well-established"},{"condition":"Mixed bacterial and protozoal diarrhea","description":"The combination covers both anaerobic bacteria and protozoa, making it suitable for mixed infections of the gut.","evidence":"Moderate"},{"condition":"Intra-abdominal infections","description":"It may be used for intra-abdominal infections caused by susceptible anaerobic bacteria, often as part of a broader regimen.","evidence":"Moderate"},{"condition":"Pelvic inflammatory disease","description":"In some cases, it is used to treat pelvic inflammatory disease caused by anaerobic bacteria, though other antibiotics are more commonly used.","evidence":"Limited"}]
Off-label uses: [{"condition":"Bacterial vaginosis","description":"Sometimes prescribed off-label for bacterial vaginosis, but not a first-line treatment.","evidence":"Limited"},{"condition":"Dental infections","description":"May be used off-label for dental abscesses caused by anaerobic bacteria, but usually other antibiotics are preferred.","evidence":"Limited"}]
Primary treatment for: Amoebic dysentery
Also treats: Giardiasis, Mixed bacterial and protozoal diarrhea, Intra-abdominal infections, Pelvic inflammatory disease
📋 Drug Information
| Generic Name(s) | Levofloxacin (125mg/5ml) + Ornidazole (125mg/5ml) |
| Brand Name | jestylox oz oral suspension |
| Manufacturer | Pritus Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not freeze. Shake well before each use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with complementary mechanisms. Levofloxacin, a fluoroquinolone, inhibits bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication, transcription, repair, and recombination. This inhibition leads to the inability of bacteria to replicate and ultimately causes bacterial cell death. Ornidazole, a nitroimidazole, enters susceptible anaerobic bacteria and protozoa, where its nitro group is reduced to reactive intermediates that bind to DNA, causing strand breakage and inhibiting nucleic acid synthesis. This results in the death of the microorganism. The combination provides broad-spectrum activity against both aerobic and anaerobic bacteria as well as protozoa, which is particularly useful in mixed infections of the gastrointestinal tract.
Mechanism Steps
💡 How to Take jestylox oz oral suspension
Strength: Each 5 ml of oral suspension contains 125 mg of levofloxacin and 125 mg of ornidazole.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 ml to 10 ml (providing 125 mg to 250 mg of levofloxacin and 125 mg to 250 mg of ornidazole) taken orally twice daily, or as directed by your physician. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and your overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 18 years due to the risk of cartilage damage associated with fluoroquinolones. |
| Elderly Dosage | Elderly patients may be more susceptible to the side effects of this medicine, especially tendon rupture, central nervous system effects, and renal impairment. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For levofloxacin, the dose should be reduced in patients with creatinine clearance less than 50 ml/min. Ornidazole may also require dose adjustment. Consult your doctor for specific dosing recommendations based on your renal function. |
| Hepatic Impairment | In patients with hepatic impairment, no specific dose adjustment is generally recommended for levofloxacin, but ornidazole should be used with caution due to its hepatic metabolism. Monitor liver function tests periodically. |
| Maximum Daily Dose | The maximum recommended daily dose is 500 mg of levofloxacin and 500 mg of ornidazole, but this must be determined by a clinician based on the individual patient's condition. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jestylox oz oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Antacids | Major | |
| Alcohol | Major | |
| NSAIDs | Moderate | |
| Theophylline | Moderate | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Caffeine | Minor | |
| Cyclosporine | Minor | |
| Probenecid | Minor |
🚨 Major Interactions
- Warfarin
- Antacids, sucralfate, iron, zinc
- Alcohol
- QT-prolonging drugs (e.g., amiodarone, sotalol, quinidine)
⚡ Moderate Interactions
- NSAIDs (e.g., ibuprofen, naproxen)
- Theophylline
- Corticosteroids
- Oral hypoglycemics (e.g., glibenclamide)
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 48 hours after the last dose. Ornidazole can cause a disulfiram-like reaction characterized by severe nausea, vomiting, flushing, headache, and tachycardia. Additionally, alcohol may worsen central nervous system side effects such as dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levofloxacin, ornidazole, or any other fluoroquinolone or nitroimidazole.","History of tendon disorders associated with fluoroquinolone use.","Myasthenia gravis (may exacerbate muscle weakness).","Pregnancy and breastfeeding, unless clearly needed.","Children under 18 years (fluoroquinolones may affect cartilage development).","Severe renal impairment (dose adjustment required).","Epilepsy or other seizure disorders (may lower seizure threshold)."]
⚠️ Warnings & Precautions
["Fluoroquinolones, including levofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and central nervous system effects. Reserve for use when no alternative treatment options are available.","Avoid alcohol during treatment and for 48 hours after the last dose due to disulfiram-like reaction with ornidazole.","May cause dizziness and drowsiness; avoid driving or operating machinery until you know how this medicine affects you.","Take with plenty of water to prevent crystallization in urine.","Do not take antacids, iron, or zinc supplements within 2 hours of this medicine.","Complete the full course of therapy even if you feel better to prevent resistance.","Inform your doctor if you have kidney or liver disease, diabetes, or heart rhythm problems.","Stop immediately and seek medical attention if you experience tendon pain, swelling, or rupture."]
🤱 Lactation Safety
Levofloxacin and ornidazole are excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, diarrhea, and central nervous system effects such as dizziness, confusion, and seizures. There is no specific antidote. Treatment should be symptomatic and supportive. Maintain adequate hydration. In case of overdose, contact a poison control center or emergency room immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Shake the bottle well before each use to ensure the medicine is evenly mixed. Measure the dose with the provided measuring cup or syringe, not a household spoon. Avoid alcohol completely during treatment and for at least 48 hours after the last dose, as it can cause a severe reaction. Inform your doctor if you have kidney or liver problems, epilepsy, myasthenia gravis, or tendon disorders. Avoid driving or operating heavy machinery if you experience dizziness. Do not take antacids, iron, or zinc supplements within 2 hours before or after this medicine, as they can reduce its absorption. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose. Store this medicine at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Complete the full course to prevent recurrence and resistance.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, central nervous system effects, and renal impairment. Dose adjustment based on renal function is often necessary. Monitor closely for side effects and ensure adequate hydration.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy due to potential risks to the fetus. Use effective contraception during treatment and for at least 48 hours after the last dose.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery and can affect wound healing. Consult your doctor for specific advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications and can increase the risk of bleeding. Your dentist may recommend postponing non-urgent procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture, especially in the Achilles tendon. If you experience any joint pain or swelling, stop exercising and consult your doctor immediately.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, and confusion, which can affect your ability to drive or operate heavy machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest if you feel unwell. Inform your employer if you need to take time off.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects such as tendon pain, severe allergic reactions, or seizures, stop the medicine and seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended and may lead to antibiotic resistance, fungal overgrowth, and rare but serious effects such as tendon rupture, peripheral neuropathy, and liver toxicity. It should only be used for the prescribed duration. If long-term therapy is required, regular monitoring of renal, hepatic, and hematologic function is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help restore gut flora and reduce antibiotic-associated diarrhea.
Evidence: ModerateEssential for managing dehydration caused by diarrhea.
Evidence: Well-establishedMay reduce the duration and severity of diarrhea in children.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the efficacy of live bacterial vaccines such as the typhoid vaccine. Avoid administering live vaccines during treatment and for several days after completion. Consult your doctor for specific timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Shake well before each use
❌ DON'T
Do not use if the suspension has changed color or consistency
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription to show customs if needed. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually to maintain even intervals. Do not expose the suspension to extreme temperatures. Always pack it in your carry-on luggage to avoid loss or temperature extremes.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24-48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, alcohol must be strictly avoided during treatment and for at least 48 hours after the last dose due to the risk of a severe disulfiram-like reaction.
A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor for advice.
🤔 Common Patient Concerns
🔄 Substitutes for jestylox oz oral suspension
View AllAlternative brands with exact same active ingredient:
-
levokos oz oral suspensionElkos Healthcare Pvt Ltd ₹45.00 18.2% CHEAPER
-
letflox oz oral suspensionBioxtreme Pharma ₹50.63 7.9% CHEAPER
-
leviox oz oral suspensionMedikem Pharmaceuticals ₹50.63 7.9% CHEAPER
-
antof lz oral suspensionProgressive Life Care ₹51.56 6.3% CHEAPER
-
Fravoq OZ Oral SuspensionFrank Medilink ₹51.56 6.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is an antibiotic and antiprotozoal; it does not work against viruses. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course to prevent recurrence and resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol can cause a severe disulfiram-like reaction with ornidazole and should be avoided. - Myth: This medicine is safe for children.
Fact: It is generally not recommended for children under 18 due to the risk of cartilage damage.
🔄 Alternative Options
Generic Alternatives
- Levofloxacin + Ornidazole oral suspension (generic)
Brand Alternatives
- Antof LZ Oral Suspension