jeclofen-p oral suspension - Aceclofenac (50mg) + Paracetamol (125mg) medicine

Alcinac-P Oral Suspension: Complete Medicine Guide

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🏭 Jovimag Lifesciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for short-term use in acute pain.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is jeclofen-p oral suspension used for?

This medicine is a combination of aceclofenac and paracetamol used for short-term relief of acute pain and fever. It works by reducing inflammation and pain. Take it with food and avoid alcohol.

  • Generic Name: Aceclofenac (50mg) + Paracetamol (125mg)
  • Manufacturer: Jovimag Lifesciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 jeclofen-p oral suspension के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटामिनोफेन और एसिटाइलसैलिसिलिक एसिड का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह मुख्य रूप से गठिया, मांसपेशियों के दर्द, दांत दर्द और बुखार के इलाज में उपयोग की जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, यकृत की क्षति, गुर्दे की समस्या और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। यदि आपको पेट में अल्सर, गुर्दे या यकृत की बीमारी है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान बिना डॉक्टर की सलाह के न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 jeclofen-p oral suspension Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgery.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever due to the paracetamol component.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used for menstrual cramps, but other NSAIDs are preferred.","evidence":"Limited"}]

Primary treatment for: Acute musculoskeletal pain

Also treats: Dental pain, Post-operative pain, Fever

📋 Drug Information

Generic Name(s)Aceclofenac (50mg) + Paracetamol (125mg)
Brand Namejeclofen-p oral suspension
ManufacturerJovimag Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine with food to minimize gastrointestinal irritation.
2
Advise patients to avoid alcohol while taking this medicine.
3
Use the lowest effective dose for the shortest duration possible.
4
Monitor renal and hepatic function in patients on prolonged therapy.
5
Caution patients about driving or operating machinery if they experience dizziness.
6
Instruct patients to report any signs of bleeding or unusual bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine contains paracetamol which reduces fever.
Likely Use
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration, with peak plasma concentrations occurring within 1.5 to 3 hours. Paracetamol is also rapidly absorbed, with peak levels within 0.5 to 2 hours. Food may delay absorption slightly but does not significantly affect the extent of absorption.
DistributionBoth drugs are distributed widely throughout the body. Aceclofenac is highly protein-bound, while paracetamol has a lower protein binding. Aceclofenac may accumulate in synovial fluid, which is beneficial for joint pain.
Protein BindingAceclofenac is approximately 99% bound to plasma proteins. Paracetamol is about 10-25% bound to plasma proteins.
MetabolismAceclofenac is metabolized in the liver primarily by CYP2C9 to inactive metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of aceclofenac is approximately 4 hours. Paracetamol has a half-life of 2 to 3 hours.
ExcretionAceclofenac and its metabolites are excreted primarily in urine. Paracetamol metabolites are excreted in urine, with about 90% excreted within 24 hours.
BioavailabilityThe oral bioavailability of aceclofenac is approximately 80-100%. Paracetamol has a high oral bioavailability of about 80-90%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached in about 1.5 to 3 hours for aceclofenac and 0.5 to 2 hours for paracetamol.
Duration of ActionThe analgesic effect lasts approximately 4 to 6 hours, and the antipyretic effect lasts 4 to 6 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a nonsteroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis and may also modulate pain perception through other pathways. Together, they provide enhanced analgesic and antipyretic effects.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Aceclofenac inhibits both COX-1 and COX-2 enzymes, reducing the conversion of arachidonic acid to prostaglandins.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to less inflammation, pain, and fever.
3
Central analgesic action of paracetamol: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain pathways.
4
Combined effect: The combination provides greater pain relief and fever reduction than either agent alone.

💡 How to Take jeclofen-p oral suspension

Strength: Each 5 mL of oral suspension contains Aceclofenac 50 mg and Paracetamol 125 mg.

1Shake the bottle well before use.
2Measure the dose using the provided measuring cup or syringe.
3Take with food or milk to reduce stomach upset.
4Swallow the suspension directly; do not mix with other liquids unless advised.
5Follow the prescribed schedule and do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 10 mL (providing 50 mg aceclofenac and 125 mg paracetamol) two to three times daily, or as prescribed by a doctor. The maximum daily dose should not exceed 30 mL (150 mg aceclofenac and 375 mg paracetamol) unless directed by a physician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of NSAIDs and paracetamol. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. Avoid in severe renal impairment (eGFR <30 mL/min).
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment.
Maximum Daily DoseThe maximum daily dose is 30 mL (150 mg aceclofenac and 375 mg paracetamol) unless otherwise prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage and GI bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of jeclofen-p oral suspension

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe or persistent, seek medical advice.
Headache (Common (5-10%))
Usually resolves on its own. If severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Drowsiness (Common (5-10%))
Avoid activities requiring alertness. Consult your doctor if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools, vomiting blood, or severe abdominal pain.
Liver damage (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Kidney impairment (Rare (<0.1%))
Notify your doctor if you experience decreased urine output, swelling, or confusion.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you develop rash, itching, swelling of face/lips/throat, or difficulty breathing.

⚠️ Rare Side Effects

Blood disorders (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor.
Pancreatitis
Seek medical attention for severe abdominal pain radiating to the back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
ACE inhibitors Moderate
Diuretics Moderate
Lithium Moderate
Antacids Minor
Cholestyramine Minor
Alcohol Major

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate

⚡ Moderate Interactions

  • ACE inhibitors and ARBs
  • Diuretics
  • Lithium

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage, especially due to paracetamol, and can increase the risk of gastrointestinal bleeding due to aceclofenac.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to aceclofenac, paracetamol, or any NSAID","Active peptic ulcer or history of recurrent peptic ulcer","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Take with food to reduce gastrointestinal irritation.","Avoid alcohol consumption.","Do not exceed recommended dose or duration.","Use with caution in elderly patients.","Monitor for signs of bleeding, especially if on anticoagulants.","Consult doctor before use if you have kidney or liver disease.","May cause dizziness; avoid driving until you know how it affects you."]

🤱 Lactation Safety

Aceclofenac and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding. Short-term use may be considered if benefits outweigh risks.

💊 Overdose Management

Overdose can cause severe liver damage, especially due to paracetamol. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders. Do not use this medicine if you are pregnant, especially in the third trimester, or breastfeeding without consulting your doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of NSAID-related gastrointestinal, renal, and cardiovascular side effects. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy if you are taking this medicine. Avoid use during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but consult your surgeon before use as it may increase bleeding risk.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may exacerbate pain while taking this medicine. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset; take with food.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or liver problems. Consult your doctor before stopping if you have been on prolonged therapy.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, and liver damage. Regular monitoring of renal and hepatic function is recommended. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Heat/cold therapy

May help relieve localized pain and inflammation.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before vaccination if you are on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with acute dental pain
Took this medicine for severe toothache. Pain relief was effective within 30 minutes. She experienced mild nausea but it subsided after taking it with a meal.
💡 Lesson: Taking this medicine with food can reduce nausea and enhance comfort.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30 to 60 minutes after taking this medicine.

Q: Can I take this medicine on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe to take this medicine with other painkillers?

A: Do not take with other NSAIDs or paracetamol-containing products without consulting your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for jeclofen-p oral suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.
  • Myth: It is safe to drink alcohol while taking this medicine.
    Fact: Alcohol increases the risk of liver damage and gastrointestinal bleeding.
  • Myth: This medicine can be used for long-term pain management.
    Fact: It is intended for short-term use only. Long-term use requires medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac + Paracetamol oral suspension (generic)

Brand Alternatives

  • Alcinac-P Oral Suspension

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Aceclofenac 50mg + Paracetamol 125mg per 5mL","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Ibuprofen + Paracetamol","composition":"Ibuprofen 100mg + Paracetamol 125mg per 5mL","onset":"30-60 minutes","duration":"4-6 hours"}]

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