iygat p eye drop - Gatifloxacin (0.3% w/v) + Prednisolone (1% w/v) medicine

Akrogat P Eye Drop: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 X-Med Medisciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 18, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 18, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden decrease in vision or loss of vision
  • Severe eye pain that does not improve with treatment
  • Swelling of the face, lips, or throat, or difficulty breathing
  • Signs of allergic reaction such as rash, itching, or hives
  • Increased redness, discharge, or swelling that worsens after starting the medicine
  • Eye injury or foreign body in the eye
  • Symptoms that do not improve within 2-3 days of starting treatment

If experiencing severe symptoms, call emergency services immediately.

What is iygat p eye drop used for?

This medicine is a combination eye drop containing gatifloxacin (an antibiotic) and prednisolone (a steroid). It is used to treat bacterial eye infections with inflammation, such as conjunctivitis and blepharitis, and to prevent infection after eye surgery. It works by killing bacteria and reducing swelling.

  • Generic Name: Gatifloxacin (0.3% w/v) + Prednisolone (1% w/v)
  • Manufacturer: X-Med Medisciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 iygat p eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों की बैक्टीरियल संक्रमण और सूजन के इलाज के लिए इस्तेमाल की जाती है। इसमें गैटीफ्लोक्सासिन नामक एंटीबायोटिक और प्रेडनिसोलोन नामक स्टेरॉयड होता है। यह आंखों में जलन, लालिमा, सूजन और दर्द को कम करने में मदद करती है। यह आमतौर पर बैक्टीरियल कंजंक्टिवाइटिस, ब्लेफेराइटिस और आंखों की सर्जरी के बाद संक्रमण रोकने के लिए दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में धुंधली दृष्टि, आंखों में जलन या खुजली, मुंह में कड़वा स्वाद और आंखों से पानी आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में एलर्जी, आंखों में तेज दर्द, आंखों का दबाव बढ़ना और संक्रमण शामिल हो सकते हैं। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले और बाद में हाथ धोएं। ड्रॉपर की टिप को आंख या किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनने से पहले हटा दें और दवा डालने के 15 मिनट बाद ही दोबारा पहनें। अन्य आई ड्रॉप्स के साथ उपयोग करते समय 5-10 मिनट का अंतराल रखें। डॉक्टर की सलाह के बिना 7 दिन से ज्यादा इस्तेमाल न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 iygat p eye drop Uses & Benefits

[{"condition":"Bacterial conjunctivitis","description":"Treats bacterial infection of the conjunctiva, reducing redness, discharge, and irritation.","evidence":"Well-established"},{"condition":"Blepharitis","description":"Helps control bacterial infection and inflammation of the eyelids.","evidence":"Well-established"},{"condition":"Keratitis","description":"Used for bacterial corneal ulcers and inflammation, under close ophthalmologic supervision.","evidence":"Well-established"},{"condition":"Post-operative ocular inflammation and infection prophylaxis","description":"Prevents infection and reduces inflammation after cataract or other eye surgeries.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Allergic conjunctivitis with suspected secondary bacterial infection","description":"Sometimes prescribed when both allergy and bacterial infection are suspected.","evidence":"Limited"}]

Primary treatment for: Bacterial eye infections with inflammation

Also treats: Bacterial conjunctivitis, Blepharitis, Keratitis, Post-operative ocular inflammation

📋 Drug Information

Generic Name(s)Gatifloxacin (0.3% w/v) + Prednisolone (1% w/v)
Brand Nameiygat p eye drop
ManufacturerX-Med Medisciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action Class
Route of AdministrationOphthalmic
StorageStore at room temperature (15-30°C). Protect from light and freezing. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture. Discard 4 weeks after opening.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying the eye drops to prevent contamination.
2
Do not touch the dropper tip to your eye or any surface, as this can introduce bacteria.
3
If you wear contact lenses, remove them before application and wait at least 15 minutes before reinserting.
4
Use the drops exactly as prescribed; do not skip doses or stop early, even if symptoms improve.
5
If you are using other eye drops, wait at least 5-10 minutes between different medications.
6
Report any eye pain, vision changes, or worsening symptoms to your doctor promptly.
7
Do not use this medicine for longer than prescribed without medical supervision.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Red eye with discharge
This medicine is commonly prescribed for bacterial conjunctivitis.
Likely Use
✅
Eye pain and swelling after surgery
Used to prevent infection and reduce inflammation post-operatively.
Likely Use
❌
Itchy, watery eyes without discharge
This medicine is not for allergic conjunctivitis unless bacterial infection is also present.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of gatifloxacin and prednisolone after topical ocular administration is minimal. Therapeutic concentrations are achieved in the tear film and ocular tissues.
DistributionBoth drugs distribute locally into the cornea, aqueous humor, and conjunctiva. Systemic distribution is negligible.
Protein BindingGatifloxacin is approximately 20% protein-bound. Prednisolone is about 70-90% protein-bound in plasma, but systemic exposure after eye drop use is very low.
MetabolismGatifloxacin undergoes minimal metabolism. Prednisolone is metabolized in the liver, primarily by CYP3A4, but systemic levels after ocular use are minimal.
Half-LifeThe elimination half-life of gatifloxacin is about 7-14 hours. Prednisolone has a plasma half-life of 2-3 hours. These values are for systemic administration; after eye drop use, systemic elimination is not clinically significant.
ExcretionGatifloxacin is excreted largely unchanged in urine. Prednisolone metabolites are excreted in urine and bile. After ocular administration, systemic excretion is minimal.
BioavailabilitySystemic bioavailability after ocular administration is very low, typically less than 5% for both components.
Onset of ActionAntibacterial effects begin within hours of application. Anti-inflammatory effects may be noticed within 1-2 days.
Peak Plasma TimePeak plasma concentrations after ocular dosing are very low and not clinically relevant. Tear film concentrations peak immediately after instillation.
Duration of ActionThe antibacterial and anti-inflammatory effects last for several hours after each dose, requiring multiple daily applications as prescribed.

How It Works

This medicine combines two active ingredients. Gatifloxacin, a fluoroquinolone antibiotic, inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, repair, and transcription, leading to bacterial cell death. Prednisolone, a corticosteroid, binds to glucocorticoid receptors in the eye, suppressing the inflammatory response by inhibiting the release of inflammatory mediators and reducing capillary permeability, thereby decreasing swelling, redness, and pain.

Mechanism Steps

1
Gatifloxacin uptake by bacteria: Gatifloxacin penetrates the bacterial cell wall and reaches the cytoplasm.
2
Inhibition of DNA gyrase and topoisomerase IV: Gatifloxacin binds to these enzymes, blocking DNA replication and causing double-strand breaks.
3
Bacterial cell death: The disruption of DNA processes leads to rapid bacterial death.
4
Prednisolone binding to glucocorticoid receptors: Prednisolone enters ocular cells and binds to cytoplasmic glucocorticoid receptors.
5
Suppression of inflammatory mediators: The receptor-ligand complex translocates to the nucleus and inhibits transcription of pro-inflammatory genes, reducing inflammation.

💡 How to Take iygat p eye drop

Strength: Gatifloxacin 0.3% w/v + Prednisolone 1% w/v ophthalmic solution

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a small pocket.
4Hold the dropper above your eye and squeeze one drop into the pocket.
5Close your eye gently and press the inner corner with your finger for 1-2 minutes to prevent drainage.
6Wipe away any excess liquid with a clean tissue.
7Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose is one drop instilled into the affected eye(s) every 4 to 6 hours, or as directed by your ophthalmologist. For severe infections, your doctor may recommend more frequent dosing initially. The dose and duration must be individualized by a qualified clinician based on the type and severity of the infection, your response to treatment, and any underlying conditions. Do not exceed the prescribed frequency or duration.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician or ophthalmologist for appropriate use in children.
Elderly DosageNo specific dosage adjustment is required for elderly patients, but they should be monitored for increased intraocular pressure and other side effects.
Renal ImpairmentNo dosage adjustment is required for renal impairment, as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustment is required for hepatic impairment, as systemic absorption is minimal.
Maximum Daily DoseThe maximum daily dose is not established from available information. Use only as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of iygat p eye drop

✅ Common Side Effects

Transient blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery. Usually resolves within minutes.
Eye irritation or burning (Common (5-10%))
This is usually temporary. If persistent or severe, consult your doctor.
Unpleasant taste (Common (5-10%))
Drink water or chew gum after application. It is harmless.
Increased tearing (Common (5-10%))
Usually resolves on its own. If excessive, consult your doctor.

🚨 Serious Side Effects

Allergic reaction (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Increased intraocular pressure (Uncommon (0.1-1%))
Requires monitoring by an eye specialist. Report eye pain or vision changes.
Secondary eye infection (fungal or viral) (Rare (<0.1%))
Consult your doctor if symptoms worsen or new symptoms appear.
Cataract formation with prolonged use (Rare (<0.1%))
Regular eye check-ups are recommended for long-term use.

⚠️ Rare Side Effects

Corneal perforation
Seek immediate ophthalmologic care.
Systemic effects from prednisolone (e.g., adrenal suppression) with prolonged use
Consult your doctor if you experience fatigue, weakness, or weight loss.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other ophthalmic corticosteroids Major
Live vaccines Major
Other eye drops Moderate
CYP3A4 inhibitors Moderate
Contact lenses Minor

🚨 Major Interactions

  • Other ophthalmic corticosteroids
  • Live vaccines

⚡ Moderate Interactions

  • Other eye drops
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

🍷 Alcohol Interaction

No significant interaction is expected with alcohol when this medicine is used as eye drops, as systemic absorption is minimal. However, excessive alcohol may worsen inflammation and delay healing.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to gatifloxacin, other quinolones, or prednisolone","Untreated viral, fungal, or mycobacterial eye infections","Acute purulent bacterial conjunctivitis (unless directed by a doctor)","Use in children under 1 year of age (safety not established)"]

⚠️ Warnings & Precautions

["Prolonged use may cause fungal or viral infections, glaucoma, or cataracts.","Do not use for more than 7 days without medical advice.","Avoid touching the dropper tip to any surface to prevent contamination.","Remove contact lenses before use and wait 15 minutes before reinserting.","If symptoms do not improve within 2-3 days, consult your doctor.","Do not use this medicine for undiagnosed red eye.","Use with caution in patients with glaucoma or a history of herpes simplex keratitis."]

🤱 Lactation Safety

It is not known whether gatifloxacin or prednisolone pass into breast milk after ocular use. Systemic absorption is minimal, but consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical nature. If accidental ingestion occurs, seek medical attention. In case of excessive eye application, rinse the eye with water and consult a doctor if irritation persists.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Wash your hands before and after using this medicine. Do not touch the dropper tip to any surface, including your eye, to avoid contamination. Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. If you are using other eye drops, wait at least 5 to 10 minutes between applications. Do not use this medicine for longer than prescribed without medical supervision. Inform your doctor if you have a history of glaucoma, cataracts, diabetes, or weakened immune system. Do not share this medicine with others. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to increased intraocular pressure and cataract formation with prolonged use. Regular eye check-ups are recommended.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy has not been fully established.

🏥 Post-Surgery Considerations

This medicine is often prescribed after eye surgery to prevent infection and reduce inflammation. Use exactly as directed by your surgeon and attend all follow-up appointments.

🦷 Dental Procedures

No specific precautions are needed for dental procedures while using this medicine.

💚 Lifestyle Tips for Better Results

🏃
Avoid touching or rubbing your eyes to prevent irritation and infection.
🥗
Wash your hands frequently, especially before and after applying eye drops.
😴
Do not share towels, pillows, or eye makeup with others during an eye infection.
💧
Follow a healthy diet rich in vitamins A, C, and E to support eye health.
🧘
Get adequate sleep to help your body heal.
🌞
Avoid wearing contact lenses until the infection is fully resolved.

🏋️ Exercise Considerations

No specific exercise restrictions are required while using this medicine. However, if you experience blurred vision after application, avoid activities that require clear vision until it resolves.

🥗 Diet Recommendations

Include foods rich in vitamin A (carrots, spinach, sweet potatoes) for eye health.
Stay hydrated to maintain tear production.
Limit processed foods and sugary drinks that can promote inflammation.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after application. Wait until your vision is clear before driving or operating machinery. Otherwise, it should not significantly affect your daily activities.

🛑 When to Stop This Medicine

Stop using this medicine only when your doctor advises. Do not stop early, even if symptoms improve, to prevent recurrence of infection. If you experience serious side effects, stop and seek medical attention immediately.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to increased intraocular pressure, glaucoma, cataract formation, and secondary infections. Regular monitoring by an ophthalmologist is recommended if long-term use is necessary. Do not use for more than 7 days without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Can help relieve discomfort and reduce swelling in bacterial eye infections.

Evidence: Well-established
Lid hygiene

Regular cleaning of eyelids can help manage blepharitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are expected with ocular use. However, if you are receiving live vaccines, consult your doctor as corticosteroids may reduce vaccine efficacy.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Discard 4 weeks after opening

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, continue your regular dosing schedule as closely as possible; consult your doctor for specific advice if needed.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with bacterial conjunctivitis
She was prescribed this medicine for redness, discharge, and swelling in her right eye. After using it as directed for 3 days, her symptoms improved significantly. She made sure to wash her hands and not touch the dropper tip to her eye.
💡 Lesson: Proper hygiene and adherence to the prescribed schedule are key to effective treatment.
👤 A 60-year-old man after cataract surgery
He was given this medicine to prevent infection and reduce inflammation after surgery. He used it regularly and attended follow-up visits. His eye healed well without complications.
💡 Lesson: Post-operative use of antibiotic-steroid drops helps prevent infection and control inflammation, but regular follow-up is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief within 1-2 days, but complete healing may take up to a week. If symptoms do not improve within 2-3 days, consult your doctor.

Q: Can I wear contact lenses while using this medicine?

A: No, you should remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them.

Q: Is it safe to use during pregnancy?

A: Consult your doctor before use. The safety of this medicine during pregnancy has not been fully established.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for dry eyes?
  • Will it affect my vision permanently?
  • Can I drive after using this medicine?
  • Does it interact with my other eye drops?
  • What if I accidentally swallow the drops?
  • Can I use it beyond the expiry date?

🔄 Substitutes for iygat p eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any red eye.
    Fact: It is only for bacterial infections with inflammation. Using it for viral or allergic eye conditions can worsen the problem.
  • Myth: It is safe to use for long periods.
    Fact: Prolonged use can cause increased eye pressure, cataracts, and secondary infections. Use only as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Gatifloxacin 0.3% + Prednisolone 1% ophthalmic solution (generic)

Brand Alternatives

  • Akrogat P Eye Drop

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Gatifloxacin 0.3% + Prednisolone 1%","class":"Fluoroquinolone + Corticosteroid","primary_use":"Bacterial eye infections with inflammation"},{"medicine":"Moxifloxacin + Dexamethasone","composition":"Moxifloxacin 0.5% + Dexamethasone 0.1%","class":"Fluoroquinolone + Corticosteroid","primary_use":"Bacterial eye infections with inflammation"},{"medicine":"Ciprofloxacin + Dexamethasone","composition":"Ciprofloxacin 0.3% + Dexamethasone 0.1%","class":"Fluoroquinolone + Corticosteroid","primary_use":"Bacterial eye infections with inflammation"}]

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