ivrea soap - Ivermectin (NA) medicine

Ivrea Soap: A Topical Ivermectin Treatment for Parasitic Skin Infections

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🏭 Ajanta Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
🤰 Pregnancy Category Not established from the available information for this specific soap formulation. Systemically absorbed ivermectin is classified as Pregnancy Category C by the FDA. Consult your doctor before using this medicine if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Limited for soap formulation; well-established for other topical ivermectin formulations in scabies.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, hives, difficulty breathing, swelling of face, lips, tongue, or throat)
  • Signs of severe skin infection (increased redness, swelling, pus, pain)
  • Blistering or peeling of the skin
  • Eye contact causing severe irritation or pain
  • Accidental ingestion, especially in children
  • No improvement or worsening of symptoms after completing treatment

If experiencing severe symptoms, call emergency services immediately.

What is ivrea soap used for?

This medicine is a topical soap containing ivermectin, used to treat parasitic skin infestations like scabies. It works by paralyzing and killing the parasites. Apply as directed by your doctor, usually to affected skin, and leave on for a specified time before rinsing.

  • Generic Name: Ivermectin (NA)
  • Manufacturer: Ajanta Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ivrea soap के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल साबुन है जिसमें आइवरमेक्टिन नामक सक्रिय तत्व होता है। इसका उपयोग त्वचा पर होने वाले परजीवी संक्रमण जैसे स्केबीज (खुजली) और जूँ के इलाज के लिए किया जाता है। यह परजीवियों को मारता है और उनके अंडों को नष्ट करता है। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में त्वचा में जलन, लालिमा, खुजली या जलन की भावना शामिल हो सकती है। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। यदि आपको गंभीर एलर्जी जैसे सूजन, चकत्ते, सांस लेने में कठिनाई या चेहरे, होंठ, जीभ या गले में सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल बाहरी त्वचा पर करें। आँखों, होंठों और श्लेष्मा झिल्ली के संपर्क से बचें। यदि गलती से संपर्क हो जाए तो पानी से अच्छी तरह धो लें। टूटी या घायल त्वचा पर इसका उपयोग न करें। बच्चों की पहुँच से दूर रखें। इसे निगलें नहीं। गर्भवती या स्तनपान कराने वाली महिलाएँ उपयोग से पहले डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 ivrea soap Uses & Benefits

  • [{"condition":"Scabies","description":"This medicine is used topically to treat scabies, a skin infestation caused by the mite Sarcoptes scabiei.
  • It helps to kill the mites and their eggs, relieving itching and preventing spread.","evidence":"Well-established for topical ivermectin in scabies treatment, though oral ivermectin is more commonly studied."},{"condition":"Pediculosis (lice infestation)","description":"Topical ivermectin may be used to treat head lice and pubic lice by paralyzing and killing the lice.","evidence":"Limited evidence for soap formulation; other topical ivermectin formulations have shown efficacy."}]

Off-label uses: [{"condition":"Rosacea","description":"Topical ivermectin is sometimes used off-label to reduce inflammation and papules in rosacea, but this soap formulation is not specifically approved for this use.","evidence":"Limited; other topical ivermectin formulations have shown benefit."},{"condition":"Demodicosis","description":"Ivermectin may be used to treat skin infestation with Demodex mites, but evidence for soap formulation is lacking.","evidence":"Limited"}]

Primary treatment for: Scabies

Also treats: Pediculosis

📋 Drug Information

Generic Name(s)Ivermectin (NA)
Brand Nameivrea soap
ManufacturerAjanta Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassEctoparasiticides
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Keep away from direct sunlight and moisture. Do not freeze.
Shelf LifeNot established from the available information for this specific product. Refer to the packaging for the expiry date.
WHO GuidelineNot established from the available information for this specific soap formulation. WHO guidelines for scabies recommend topical permethrin or oral ivermectin; topical ivermectin is not specifically mentioned.
ICMR GuidelineNot established from the available information for this specific soap formulation.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine to clean, dry skin and avoid contact with eyes and mucous membranes.
2
For scabies, treat all household members and close contacts simultaneously to prevent reinfestation.
3
Wash all clothing, bedding, and towels in hot water and dry on high heat to kill any remaining mites.
4
Do not use this medicine for longer than prescribed without consulting your doctor.
5
If your skin condition worsens or does not improve after treatment, contact your healthcare provider.
6
Keep the soap out of reach of children and store it at room temperature.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Intense itching, especially at night
This medicine is commonly prescribed for scabies, which causes intense itching.
Likely Use
Rash with small red bumps or burrow lines on skin
This medicine is used to treat scabies rash.
Likely Use
Visible lice or nits in hair
This medicine may be used for lice infestation.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Dry, scaly skin without itching
This medicine is not for general dry skin.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information for this specific soap formulation. Systemic absorption of topical ivermectin is generally low, but may vary depending on the integrity of the skin and the amount applied.
DistributionNot established from the available information for this specific soap formulation. After topical application, ivermectin is thought to remain largely in the skin layers, with minimal systemic distribution.
Protein BindingNot established from the available information for this specific soap formulation. For oral ivermectin, protein binding is approximately 93%.
MetabolismNot established from the available information for this specific soap formulation. Orally administered ivermectin is primarily metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4.
Half-LifeNot established from the available information for this specific soap formulation. For oral ivermectin, the elimination half-life is approximately 18 hours.
ExcretionNot established from the available information for this specific soap formulation. Orally administered ivermectin is mainly excreted in feces, with less than 1% excreted in urine.
BioavailabilityNot established from the available information for this specific soap formulation. The systemic bioavailability of topical ivermectin is expected to be low.
Onset of ActionNot established from the available information for this specific soap formulation. Clinical improvement in parasitic skin conditions may be seen within days to weeks.
Peak Plasma TimeNot established from the available information for this specific soap formulation.
Duration of ActionNot established from the available information for this specific soap formulation.

How It Works

Ivermectin binds to glutamate-gated chloride channels and gamma-aminobutyric acid (GABA) receptors in the nerve and muscle cells of parasites. This binding increases the permeability of the cell membrane to chloride ions, leading to hyperpolarization and paralysis of the parasite. The parasite eventually dies or is unable to feed and reproduce. In humans, GABA receptors are located in the central nervous system, and ivermectin does not readily cross the blood-brain barrier at therapeutic doses, which is why it is generally safe for human use. When applied topically, ivermectin acts locally on the skin surface and within the skin layers to target the parasites.

Mechanism Steps

1
Binding to parasite channels: Ivermectin binds to glutamate-gated chloride channels and GABA receptors in the nerve and muscle cells of the parasite.
2
Increased chloride permeability: This binding causes an influx of chloride ions into the cells, leading to hyperpolarization.
3
Paralysis of parasite: The hyperpolarization results in paralysis of the parasite's muscles and nerves, preventing movement and feeding.
4
Death of parasite: The parasite eventually dies due to inability to feed and reproduce, and is shed from the skin.

💡 How to Take ivrea soap

Strength: Soap formulation containing ivermectin (strength not specified).

1Wet the affected area with water.
2Apply the soap to the affected area and lather gently.
3Leave the lather on the skin for the duration recommended by your doctor (e.g., 10-15 minutes for scabies).
4Rinse thoroughly with water.
5Pat the skin dry with a clean towel.
6Wash your hands after use.
7Avoid contact with eyes, mouth, and other mucous membranes.

Dosage Information

Adult DosageThe dosage of this medicine must be individualized by a qualified clinician based on the specific condition being treated, its severity, and the patient's response. Typically, the soap is applied to affected areas of the skin as directed by the physician. It is important to follow the prescribed frequency and duration of use. Do not use more than the recommended amount or for longer than prescribed. For scabies, it is often applied from the neck down, left on for a certain period, and then washed off. The exact instructions will be provided by your healthcare provider.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.
Elderly DosageElderly patients may use this medicine as directed by a physician. No specific dosage adjustments are established for topical use, but caution is advised due to potentially thinner skin and increased sensitivity.
Renal ImpairmentNo dosage adjustment is established for topical use in patients with renal impairment. However, consult a doctor before use if you have kidney disease.
Hepatic ImpairmentNo dosage adjustment is established for topical use in patients with hepatic impairment. However, consult a doctor before use if you have liver disease.
Maximum Daily DoseNot established from the available information for this specific soap formulation. Use only as directed by your healthcare provider.

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled application
→ Apply it as soon as you remember.
💡 If it is almost time for your next application, skip the missed one and continue with your regular schedule.
📌 If you miss more than one application
→ Consult your doctor for advice.
💡 Do not double the amount or frequency to catch up.

⚠️ Side Effects of ivrea soap

✅ Common Side Effects

Skin irritation (Common (may affect up to 1 in 10 people))
Usually resolves on its own. If persistent or severe, consult your doctor.
Redness (Common)
May diminish with continued use. Avoid applying to broken skin.
Itching (Common)
Can be a sign of the underlying condition or irritation. Consult doctor if worsening.
Burning sensation (Common)
Usually temporary. Discontinue if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare)
Seek immediate medical attention if you experience rash, hives, difficulty breathing, or swelling of face, lips, tongue, or throat.
Severe skin reaction (e.g., blistering, peeling) (Rare)
Stop use and consult a doctor immediately.

⚠️ Rare Side Effects

Secondary infection
Consult a doctor if you notice increased redness, swelling, pus, or pain.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ivermectin or any component of the formulation","Use on broken or irritated skin","Use in the eyes or mucous membranes"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes, lips, and mucous membranes.","Do not use on children under 2 years of age unless directed by a doctor.","Consult a doctor if you are pregnant or breastfeeding.","Do not use for prolonged periods without medical supervision.","Keep out of reach of children.","If condition worsens or does not improve, consult a doctor."]

🤱 Lactation Safety

Not established from the available information for this specific soap formulation. It is not known whether topically applied ivermectin is excreted in breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this soap is unlikely due to its topical route. If accidental ingestion occurs, seek immediate medical attention or contact a poison control center. Symptoms of oral ivermectin overdose may include nausea, vomiting, diarrhea, abdominal pain, dizziness, headache, and in severe cases, seizures, coma, and respiratory failure. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, lips, and mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use this medicine on broken or irritated skin unless directed by a doctor. Keep out of reach of children. Do not swallow. If you are pregnant or breastfeeding, consult your doctor before using this product. Do not use this medicine for any condition other than the one it was prescribed for. Wash your hands before and after applying the soap. Use only as directed by your healthcare provider. Do not share this medicine with others, even if they have the same symptoms. Store at room temperature, away from direct sunlight and moisture. If your symptoms do not improve or worsen after using this medicine, contact your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have thinner, more sensitive skin and may be more prone to irritation from topical products. Use with caution and monitor for adverse reactions. No specific dosage adjustments are established.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical ivermectin is generally considered low risk due to minimal systemic absorption, but safety in pregnancy has not been fully established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine on or near surgical wounds. Avoid applying to broken skin or incisions unless directed by a healthcare professional.

🦷 Dental Procedures

There are no specific considerations for dental procedures while using this medicine. However, inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Wash all clothing, bedding, and towels in hot water and dry on high heat to kill mites and lice.
🥗
Avoid close physical contact with others until you have completed treatment to prevent spread.
😴
Keep your fingernails short and clean to prevent secondary bacterial infections from scratching.
💧
Maintain good personal hygiene, but avoid over-washing which can dry out the skin.
🧘
Follow up with your doctor to ensure the infestation has cleared.

🏋️ Exercise Considerations

There are no specific exercise restrictions while using this medicine. However, if you have scabies, avoid close contact sports until treatment is complete to prevent spreading the infestation to others. If you experience skin irritation, avoid activities that cause excessive sweating or friction on the affected areas.

🥗 Diet Recommendations

Stay well hydrated to maintain healthy skin.
Eat a balanced diet rich in vitamins and minerals to support skin health.
Include foods high in vitamin C and zinc to aid skin repair.
Avoid excessive alcohol consumption, which can dehydrate the skin.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience skin irritation or discomfort, you may choose to avoid activities that require concentration. For scabies, you may need to take time off work or school until you have completed the first treatment to avoid spreading the infestation.

🛑 When to Stop This Medicine

Stop using this medicine if you experience a severe allergic reaction or severe skin irritation. Do not stop treatment prematurely unless instructed by your doctor, as the infestation may not be fully eradicated. If your symptoms do not improve after completing the prescribed course, consult your doctor before using more.

📅 Long-Term Use Effects

Long-term use of this medicine without medical supervision is not recommended. Prolonged use may lead to skin irritation or sensitization. If your condition persists or recurs, consult a doctor for further evaluation. There is no established data on the long-term effects of topical ivermectin soap.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Permethrin cream

A topical medication commonly used to treat scabies and lice. It is applied and washed off after a specified time.

Evidence: Well-established
Oral ivermectin

Tablets taken by mouth to treat scabies and other parasitic infections.

Evidence: Well-established
Crotamiton cream

A topical antipruritic and scabicide, applied for 2-5 days.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you have an active skin infection, consult your doctor about the timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C).

❌ DON'T

Do not refrigerate or freeze.

✅ DO

Keep in the original container with the cap tightly closed.

❌ DON'T

Do not transfer to another container.

✅ DO

Keep away from direct sunlight and moisture.

❌ DON'T

Do not store in the bathroom.

✅ DO

Keep out of reach of children and pets.

❌ DON'T

Do not use after the expiry date.

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in its original packaging with the prescription label intact. Carry a copy of your prescription or a letter from your doctor stating the medical condition and the need for the medication. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. If traveling across time zones, continue using the medicine as prescribed; topical application is not affected by time zone changes. Check the customs regulations of your destination country regarding prescription medications. Always declare your medication if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with intense itching and a rash between her fingers and wrists.
She was diagnosed with scabies and prescribed this medicine. She applied it as directed from the neck down, left it on for 15 minutes, and rinsed off. She also washed all her bedding and clothes in hot water. Within a week, her itching significantly reduced, and the rash began to clear. She noted that applying a moisturizer after rinsing helped with mild dryness.
💡 Lesson: Consistent application and simultaneous cleaning of personal items are key to successful treatment and preventing reinfestation.
👤 A 45-year-old man with head lice infestation unresponsive to other treatments.
He was advised to use this medicine as a shampoo-like application on his scalp. He applied it to his scalp and hair, left it on for 10 minutes, and rinsed thoroughly. He repeated the treatment after one week as instructed. The lice were eliminated, and he experienced only mild scalp irritation that resolved on its own.
💡 Lesson: This medicine can be effective for lice when used correctly, but repeat treatment may be necessary to kill newly hatched lice.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to see improvement in symptoms within a few days, but it may take up to 2-4 weeks for the infestation to completely resolve. Itching can persist for a few weeks after treatment due to an allergic reaction to dead mites.

Q: Can I use this soap every day?

A: Use it only as directed by your doctor. Typically, it is applied once and then repeated after a week or two, depending on the condition. Do not use it more often than prescribed.

Q: Is this soap safe for children?

A: Consult a pediatrician before using this medicine on children. Safety and efficacy in children under 2 years are not established.

Q: What if I accidentally swallow this soap?

A: Seek immediate medical attention or contact a poison control center. Do not induce vomiting unless instructed by a healthcare professional.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this soap on my face?
  • How often should I use this soap?
  • Is it safe to use during pregnancy?
  • Can I use it on my children?
  • What should I do if I get it in my eyes?
  • Will it cure my scabies completely?

🔄 Substitutes for ivrea soap

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Ivermectin soap can cure COVID-19.
    Fact: There is no scientific evidence that topical ivermectin can prevent or treat COVID-19. It is intended for parasitic skin infections only.
  • Myth: Ivermectin soap is a general antiseptic.
    Fact: This medicine is not an antiseptic; it specifically targets certain parasites. It should not be used for general hygiene or wound care.
  • Myth: You can use ivermectin soap for any skin rash.
    Fact: This medicine is only for specific parasitic infestations. Using it for other rashes may delay correct treatment and cause irritation.

📊 Comparison with Similar Medicines

[{"medicine":"Permethrin cream","class":"Pyrethroid","route":"Topical","primary_use":"Scabies, lice","notes":"Often first-line for scabies; applied and washed off after 8-14 hours."},{"medicine":"Oral ivermectin","class":"Avermectin","route":"Oral","primary_use":"Scabies, strongyloidiasis","notes":"Taken as tablets; systemic absorption."}]

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