Biotax SB 1000 mg/500 mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or wheezing
- Swelling of the face, lips, tongue, or throat
- Severe or bloody diarrhea
- Rash with fever or blistering
- Decreased urine output or swelling in the legs
- Yellowing of the skin or eyes
- Unusual bleeding or bruising
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is ivimax 1000 mg/500 mg injection used for?
This medicine is a combination antibiotic injection containing cefotaxime and sulbactam. It is used to treat serious bacterial infections. It works by killing bacteria and preventing them from producing enzymes that would destroy the antibiotic. It is given by a healthcare professional.
- Generic Name: Cefotaxime (1000mg) + Sulbactam (500mg)
- Manufacturer: Vhb Life Sciences Inc
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ivimax 1000 mg/500 mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफोटैक्साइम और सल्बैक्टम का संयोजन है, जिसका उपयोग गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र, मूत्र मार्ग, त्वचा, रक्त और अन्य अंगों के संक्रमण में प्रभावी है। यह इंजेक्शन के रूप में डॉक्टर या नर्स द्वारा दिया जाता है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, दस्त, मतली, उल्टी, और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और गंभीर दस्त हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा दी जानी चाहिए। इसे स्वयं न लगाएं। उपयोग से पहले अपने डॉक्टर को किसी भी एलर्जी, गुर्दे या यकृत की समस्या के बारे में बताएं। उपचार के दौरान डॉक्टर द्वारा बताई गई सावधानियों का पालन करें। बिना डॉक्टर की सलाह के दवा बंद न करें।
💊 ivimax 1000 mg/500 mg injection Uses & Benefits
[{"condition":"Lower respiratory tract infections","description":"Used to treat community-acquired and hospital-acquired pneumonia, bronchitis, and other bacterial lung infections.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against complicated and uncomplicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats cellulitis, abscesses, wound infections, and other bacterial skin infections.","evidence":"Well-established"},{"condition":"Bloodstream infections","description":"Used for bacteremia and sepsis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Meningitis","description":"Cefotaxime is a preferred agent for bacterial meningitis in many age groups due to its CNS penetration.","evidence":"Well-established"},{"condition":"Gynecological infections","description":"Treats pelvic inflammatory disease, endometritis, and other infections of the female reproductive tract.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for peritonitis and intra-abdominal abscesses.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"May be used for osteomyelitis and septic arthritis caused by susceptible bacteria.","evidence":"Established"}]
Off-label uses: [{"condition":"Prophylaxis in surgical procedures","description":"Sometimes used before certain surgeries to prevent infection, though other agents are more commonly recommended.","evidence":"Limited"},{"condition":"Neutropenic fever","description":"May be used as part of empiric therapy in cancer patients with low white blood cell counts and fever.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Pneumonia, Urinary tract infection, Cellulitis, Meningitis, Sepsis, Pelvic inflammatory disease
📋 Drug Information
| Generic Name(s) | Cefotaxime (1000mg) + Sulbactam (500mg) |
| Brand Name | ivimax 1000 mg/500 mg injection |
| Manufacturer | Vhb Life Sciences Inc |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Parenteral (intramuscular or intravenous) |
| Storage | Store the unreconstituted powder at room temperature between 20°C and 25°C (68°F to 77°F). Protect from light and moisture. Once reconstituted, the solution should be used within the time specified by the manufacturer, typically within 1 hour for intravenous use or up to 24 hours if refrigerated. Follow the instructions provided by your healthcare facility. |
| Shelf Life | The shelf life of the unreconstituted product is typically 24 to 36 months from the date of manufacture. Check the expiry date on the packaging. Do not use if expired. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefotaxime is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis and death. Sulbactam is a beta-lactamase inhibitor that irreversibly binds to certain beta-lactamase enzymes produced by bacteria, thereby protecting cefotaxime from enzymatic degradation and extending its spectrum of activity against beta-lactamase-producing strains.
Mechanism Steps
💡 How to Take ivimax 1000 mg/500 mg injection
Strength: Each vial contains cefotaxime sodium equivalent to 1000 mg of cefotaxime and sulbactam sodium equivalent to 500 mg of sulbactam.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the type and severity of infection, the patient's age, weight, kidney and liver function, and other factors. For many infections, a common adult dose is 1 to 2 grams of cefotaxime every 6 to 12 hours, but the exact dose and frequency must be determined by your doctor. The sulbactam component is fixed in a 2:1 ratio with cefotaxime. Do not self-administer; this medicine is given by a healthcare professional. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Doses are typically based on weight and the severity of infection, and must be determined by a qualified clinician. |
| Elderly Dosage | Elderly patients may have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on kidney function. Your doctor will determine the appropriate dose. |
| Renal Impairment | In patients with kidney impairment, the dose and/or dosing interval of this medicine should be adjusted according to the degree of impairment. Your doctor will calculate the appropriate dose based on your creatinine clearance. Close monitoring of kidney function is recommended. |
| Hepatic Impairment | No specific dose adjustment is generally required for liver impairment alone, but caution is advised in patients with both liver and kidney disease. Your doctor will determine the appropriate dose. |
| Maximum Daily Dose | The maximum daily dose should not exceed 12 grams of cefotaxime per day, but the exact limit depends on the clinical situation and must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ivimax 1000 mg/500 mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Warfarin | Major | |
| Furosemide | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Methotrexate | Minor |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin)
- Warfarin
- Loop diuretics (e.g., furosemide)
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol does not directly interact with this medicine, but it can worsen dehydration and gastrointestinal side effects. It is advisable to avoid alcohol during treatment, especially if you have an infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to cefotaxime, sulbactam, or other cephalosporins","Known severe allergy to penicillins (cross-reactivity possible)","Previous anaphylactic reaction to beta-lactam antibiotics"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney impairment; dose adjustment may be needed.","Use with caution in patients with liver disease.","May cause Clostridioides difficile-associated diarrhea; monitor for severe diarrhea.","Serious allergic reactions, including anaphylaxis, can occur. Discontinue immediately if suspected.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","May interfere with certain laboratory tests, such as urine glucose tests.","Not effective against viral infections.","Should be used only when a bacterial infection is confirmed or strongly suspected."]
🤱 Lactation Safety
Cefotaxime and sulbactam are excreted in human milk in low concentrations. The amount ingested by a nursing infant is usually small and unlikely to cause harm, but it may affect the infant's gut flora and lead to diarrhea or thrush. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with this medicine is unlikely due to its parenteral administration in a healthcare setting. If overdose is suspected, treatment should be symptomatic and supportive. Cefotaxime and sulbactam can be removed by hemodialysis in cases of severe toxicity, especially in patients with renal failure.
⏰ Missed Dose
This medicine is administered by a healthcare professional, so missed doses are unlikely. If you miss a scheduled dose, contact your doctor or nurse as soon as possible. Do not attempt to self-administer an extra dose.
Additional Safety Advice
This medicine must only be administered by a healthcare professional. Before receiving it, inform your doctor about any allergies, especially to penicillins or cephalosporins, and about any kidney or liver problems you may have. Do not self-administer this injection. If you experience any signs of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or a rapid heartbeat, seek emergency medical help immediately. Diarrhea that is severe or lasts after treatment may be a sign of a serious bowel infection and should be reported to your doctor. Your doctor may monitor your kidney and liver function, as well as your blood counts, during treatment. Do not skip doses or stop treatment early, even if you feel better, as this can lead to resistance and recurrence of the infection.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary. They may also be more susceptible to side effects such as confusion or seizures. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting this medicine. It is generally considered safe in pregnancy when needed, but the decision should be made with your healthcare provider.
🏥 Post-Surgery Considerations
This medicine may be used to treat or prevent infections after surgery. If you have recently had surgery, inform your surgeon and anesthesiologist about all medications you are taking, including this one.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine, as it may affect the choice of antibiotics for dental procedures or interact with other medications. Good oral hygiene is important during treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While recovering from a serious infection, avoid strenuous exercise until you feel fully recovered. Light activity such as walking is fine, but consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you may need to take time off work during treatment. You should not drive or operate heavy machinery if you feel weak, dizzy, or unwell. Follow your doctor's advice regarding rest and return to work.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping early can lead to recurrence of infection and antibiotic resistance. Your doctor will determine when to stop based on your clinical response and test results.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, superinfections with fungi or resistant bacteria, and rarely, blood disorders or kidney problems. Prolonged therapy should be guided by clinical response and culture results. Regular monitoring of kidney function, liver function, and blood counts may be necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild infections, oral antibiotics may be used instead of injections.
Evidence: Well-establishedDepending on the bacteria and its susceptibility, other antibiotics like ceftriaxone or piperacillin-tazobactam may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are due for any vaccinations, inform your doctor. Live vaccines should generally be avoided during acute infection.
📦 Storage Guide
✅ DO
Store the unreconstituted powder at room temperature (20-25°C)
❌ DON'T
Do not freeze the powder
✅ DO
Protect from light and moisture
❌ DON'T
Do not store in the bathroom
✅ DO
Use reconstituted solution within the recommended time
❌ DON'T
Do not use if the solution is cloudy or contains particles
✈️ Traveling with This Medicine
This medicine is given in a healthcare setting, so travel is not typically applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed, and declare it at customs if required. Consult your doctor before traveling if you are still on treatment.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours after starting treatment, but it is important to complete the full course as prescribed.
A: No, this medicine must be given by a healthcare professional in a clinical setting.
A: Inform your doctor before receiving this medicine. There is a risk of cross-reactivity between penicillins and cephalosporins.
A: It is generally considered safe when clearly needed, but you should consult your doctor to weigh the benefits and risks.
🤔 Common Patient Concerns
🔄 Substitutes for ivimax 1000 mg/500 mg injection
View AllAlternative brands with exact same active ingredient:
-
effimax plus 1000 mg/500 mg injectionAbbott ₹29.80 54.6% CHEAPER
-
sultax 1000 mg/500 mg injectionIpca Laboratories Ltd ₹32.55 50.4% CHEAPER
-
osotax-s 1000mg/500mg injectionOsper Formulations Pvt Ltd ₹32.59 50.3% CHEAPER
-
Taxtam 1000 mg/500 mg InjectionOrchid Chemicals & Pharmaceuticals Ltd ₹32.80 50% CHEAPER
-
cefup 1000 mg/500 mg injectionSanat Products Ltd ₹32.83 50% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop the injection once you feel better.
Fact: You must complete the full course as prescribed by your doctor, even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe to self-administer at home.
Fact: This medicine must be given by a healthcare professional in a clinical setting. Self-administration can be dangerous.
🔄 Alternative Options
Generic Alternatives
- Cefotaxime + Sulbactam injection (generic)
Brand Alternatives
- Biotax SB 1000 mg/500 mg injection