Evict Fibre Granules: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain
- Blood in stool or vomit
- Severe diarrhea with dehydration
- Signs of allergic reaction (rash, swelling, difficulty breathing)
- Muscle weakness or irregular heartbeat (electrolyte imbalance)
- Inability to pass stool with vomiting (possible obstruction)
If experiencing severe symptoms, call emergency services immediately.
What is isablac powder used for?
This medicine is a combination laxative containing lactulose and ispaghula, used to treat constipation by softening stool and adding bulk. It is taken orally as granules dissolved in water.
- Generic Name: Lactulose (10gm) + Ispaghula (3.5gm)
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 isablac powder के बारे में (Hindi Summary)
उपयोग: यह दवा कब्ज के इलाज के लिए इस्तेमाल की जाती है। यह लैक्टुलोज़ और इस्पघुला का मिश्रण है जो मल को नरम करता है और उसमें मात्रा बढ़ाता है, जिससे मल त्याग आसान हो जाता है। यह गर्भावस्था, बुजुर्गों और सर्जरी के बाद होने वाली कब्ज में भी प्रभावी है।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट फूलना, गैस, पेट में ऐंठन और जी मिचलाना शामिल हैं। ये आमतौर पर शुरुआत में होते हैं और धीरे-धीरे कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर पेट दर्द, दस्त, निर्जलीकरण और इलेक्ट्रोलाइट असंतुलन शामिल हो सकते हैं।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पर्याप्त पानी पिएं। अन्य जुलाब के साथ न लें। यदि 7 दिनों तक कब्ज बनी रहे तो डॉक्टर से मिलें। मधुमेह रोगी अपने शुगर की निगरानी करें।
💊 isablac powder Uses & Benefits
[{"condition":"Chronic constipation","description":"This medicine helps relieve chronic constipation by softening the stool and promoting regular bowel movements.","evidence":"Well-established"},{"condition":"Constipation in pregnancy","description":"It is considered safe for use during pregnancy to relieve constipation, as it is not significantly absorbed into the bloodstream.","evidence":"Well-established"},{"condition":"Constipation in elderly","description":"Elderly patients often suffer from constipation due to reduced mobility and medication use; this medicine provides gentle relief.","evidence":"Well-established"},{"condition":"Post-operative constipation","description":"Used to prevent straining after surgery, which can be harmful.","evidence":"Well-established"},{"condition":"Hemorrhoids","description":"By softening stool, it reduces straining and pain associated with hemorrhoids.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Hepatic encephalopathy","description":"Lactulose is used off-label to reduce blood ammonia levels in patients with liver disease, though this combination product is not specifically approved for this use.","evidence":"Limited"}]
Primary treatment for: Constipation
Also treats: Hemorrhoids, Post-operative constipation, Pregnancy-related constipation
📋 Drug Information
| Generic Name(s) | Lactulose (10gm) + Ispaghula (3.5gm) |
| Brand Name | isablac powder |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two laxatives with complementary mechanisms. Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. It passes to the colon where it is metabolized by bacteria into organic acids, primarily lactic acid and acetic acid. These acids draw water into the colon osmotically, softening the stool and increasing stool volume, which stimulates peristalsis. Ispaghula is a bulk-forming laxative composed of mucilage from Plantago ovata seeds. It absorbs water to form a gel-like substance, increasing stool bulk and moisture, which promotes bowel movements by stretching the intestinal wall and stimulating peristalsis. Together, they provide both osmotic and bulk-forming effects for effective relief of constipation.
Mechanism Steps
💡 How to Take isablac powder
Strength: Each sachet contains lactulose 10 gm and ispaghula 3.5 gm.
Dosage Information
| Adult Dosage | The usual adult dose is 1-2 sachets (each containing lactulose 10 gm and ispaghula 3.5 gm) taken orally, once or twice daily, preferably with a full glass of water. The dose may be adjusted based on response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require a lower dose due to increased sensitivity. Start with 1 sachet daily and adjust as needed. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is required for renal impairment, but use with caution in patients with severe renal impairment due to risk of electrolyte imbalance. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment. However, in severe hepatic impairment, lactulose may be used for hepatic encephalopathy, but this combination is not indicated for that purpose. |
| Maximum Daily Dose | The maximum recommended daily dose is 4 sachets (40 gm lactulose and 14 gm ispaghula). Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of isablac powder
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other laxatives | Major | |
| Antidiabetic drugs | Moderate | |
| Diuretics | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Other laxatives
- Antidiabetic drugs
⚡ Moderate Interactions
- Diuretics
- Cardiac glycosides (e.g., digoxin)
🍷 Alcohol Interaction
Alcohol may worsen dehydration and electrolyte imbalance caused by diarrhea. Avoid excessive alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Intestinal obstruction","Intestinal perforation","Severe inflammatory bowel disease (e.g., ulcerative colitis, Crohn's disease)","Galactosemia","Known allergy to lactulose or ispaghula"]
⚠️ Warnings & Precautions
["Do not use in patients with undiagnosed abdominal pain.","Use with caution in diabetics as lactulose may affect blood sugar.","Ensure adequate fluid intake to prevent dehydration.","Avoid use in patients with difficulty swallowing, as ispaghula can cause choking.","Do not take within 2 hours of other medications, as ispaghula may reduce their absorption."]
🤱 Lactation Safety
This medicine is considered safe during breastfeeding as it is not significantly absorbed into the bloodstream. Consult your doctor for guidance.
💊 Overdose Management
Overdose may cause severe diarrhea, abdominal cramps, and electrolyte imbalance. Treatment is symptomatic and supportive. Stop the medicine and seek medical attention. Maintain hydration and electrolyte balance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Drink plenty of water throughout the day to help the medicine work effectively. Take this medicine with a full glass of water. Do not take it immediately before lying down. If you have diabetes, monitor your blood sugar levels as lactulose may affect them. Avoid taking other laxatives without consulting your doctor. If constipation persists after 7 days of use, consult your doctor. Do not use this medicine if you have a known allergy to any of its ingredients. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to electrolyte imbalances. Start with a lower dose and monitor hydration.
🤰 Pregnancy Planning (TTC)
This medicine is considered safe during pregnancy. Consult your doctor before planning pregnancy if you are on long-term therapy.
🏥 Post-Surgery Considerations
It is often used after surgery to prevent straining. Follow your surgeon's instructions.
🦷 Dental Procedures
No specific precautions. Inform your dentist if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions. Regular physical activity can help relieve constipation.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause bloating or cramps initially, which could affect concentration. However, it does not usually impair driving or operating machinery.
🛑 When to Stop This Medicine
Stop if you experience severe diarrhea, abdominal pain, or allergic reactions. Consult your doctor before stopping if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use may lead to laxative dependence and electrolyte imbalances. It is generally recommended for short-term use. If constipation persists, consult your doctor to address underlying causes.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing fiber intake can help relieve constipation naturally.
Evidence: Well-establishedMay improve gut health and regularity.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, continue your regular dosing schedule. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It usually takes 24 to 48 hours to produce a bowel movement, but may take up to 3 days for full effect.
A: It can be taken daily for short periods, but consult your doctor for long-term use.
A: Lactulose may increase blood sugar levels. Diabetics should monitor their glucose and consult their doctor.
🤔 Common Patient Concerns
🔄 Substitutes for isablac powder
View AllAlternative brands with exact same active ingredient:
-
osilax syrupOzone Pharmaceuticals Ltd ₹88.00 47.9% CHEAPER
-
fiber forte powderPanacea Biotec Ltd ₹168.75 SAME PRICE
-
osilax powderOzone Pharmaceuticals Ltd ₹175.31 3.9% COSTLIER
-
lakzativ granulesZydus Cadila ₹190.00 12.6% COSTLIER
-
lactilax 10gm/3.5gm powderAvis Lifecare Pvt Ltd ₹195.00 15.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is habit-forming.
Fact: This medicine is not habit-forming when used as directed. However, prolonged use may lead to dependence on laxatives. - Myth: It can be taken without water.
Fact: It must be taken with plenty of water to prevent choking and ensure effectiveness.
🔄 Alternative Options
Generic Alternatives
- Lactulose solution
- Ispaghula husk
Brand Alternatives
- Evict Fibre Granules