ipradin ls 50mcg/20mcg inhaler - Levosalbutamol (50mcg) + Ipratropium (20mcg) medicine

Iprasure Inhaler: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Divine Savior Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Worsening of breathing immediately after using the inhaler (paradoxical bronchospasm).
  • Severe chest pain, palpitations, or irregular heartbeat.
  • Swelling of the face, lips, tongue, or throat (signs of allergic reaction).
  • Difficulty urinating or inability to pass urine.
  • Severe headache with blurred vision or eye pain.
  • High fever with worsening breathlessness.
  • Coughing up blood or blood-tinged sputum.

If experiencing severe symptoms, call emergency services immediately.

What is ipradin ls 50mcg/20mcg inhaler used for?

This medicine is a combination inhaler containing levosalbutamol and ipratropium, used for maintenance therapy in asthma and COPD. It works by relaxing airway muscles and reducing mucus secretion, providing relief from bronchospasm. It is not for acute attacks; always keep a rescue inhaler handy.

  • Generic Name: Levosalbutamol (50mcg) + Ipratropium (20mcg)
  • Manufacturer: Divine Savior Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ipradin ls 50mcg/20mcg inhaler के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसाल्बुटामोल और आइप्रेट्रोपियम का संयोजन है, जिसका उपयोग अस्थमा और क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज (सीओपीडी) के रखरखाव उपचार में किया जाता है। यह श्वसन मार्ग की मांसपेशियों को आराम देकर और बलगम को कम करके सांस लेने में मदद करती है। यह दवा तीव्र दौरे के लिए नहीं है, इसलिए हमेशा एक रेस्क्यू इनहेलर साथ रखें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, कंपन, घबराहट, गले में जलन और मुंह सूखना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में सांस की तकलीफ बढ़ना, दिल की धड़कन तेज होना, एलर्जी और पेशाब रुकना शामिल हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के बताए अनुसार ही करें। निर्धारित मात्रा से अधिक न लें। हर बार इनहेलर लेने के बाद मुंह को पानी से धोएं। आंखों में स्प्रे न करें। अचानक सांस की तकलीफ के लिए हमेशा रेस्क्यू इनहेलर साथ रखें। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड, या ग्लूकोमा है तो डॉक्टर को बताएं। डॉक्टर की सलाह के बिना दवा बंद न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ipradin ls 50mcg/20mcg inhaler Uses & Benefits

[{"condition":"Asthma","description":"Used as maintenance therapy to control symptoms and prevent exacerbations in patients with persistent asthma not adequately controlled by a single bronchodilator.","evidence":"Well-established"},{"condition":"Chronic Obstructive Pulmonary Disease (COPD)","description":"Helps relieve bronchospasm and improve lung function in patients with COPD, reducing symptoms and exacerbations.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Exercise-induced bronchoconstriction","description":"Sometimes prescribed off-label to prevent exercise-induced narrowing of airways, but not a first-line choice.","evidence":"Limited"}]

Primary treatment for: Asthma and Chronic Obstructive Pulmonary Disease (COPD)

Also treats: Chronic bronchitis, Emphysema, Exercise-induced bronchoconstriction

📋 Drug Information

Generic Name(s)Levosalbutamol (50mcg) + Ipratropium (20mcg)
Brand Nameipradin ls 50mcg/20mcg inhaler
ManufacturerDivine Savior Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationInhalation
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture. Keep the inhaler in its original packaging. Do not puncture or incinerate the canister. Avoid freezing.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always use a spacer device with the inhaler if prescribed, to ensure the medicine reaches your lungs effectively.
2
Rinse your mouth with water after each use to prevent oral thrush.
3
Keep a short-acting rescue inhaler (like salbutamol) with you at all times for sudden breathing difficulty.
4
Do not exceed the prescribed number of puffs per day, as it can increase the risk of heart-related side effects.
5
Inform your doctor if you have glaucoma, urinary problems, or heart disease before using this medicine.
6
Regularly check the dose counter on the inhaler and refill before it runs out.
7
Avoid spraying the inhaler near your eyes to prevent blurred vision or irritation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Shortness of breath
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing
This medicine helps relieve wheezing.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Chest pain
This medicine is not for chest pain; seek medical help.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing inhalation, levosalbutamol and ipratropium are absorbed systemically to varying degrees. A portion of the dose is swallowed and absorbed from the gastrointestinal tract, but the majority of the therapeutic effect is local in the lungs. Systemic absorption of levosalbutamol is rapid, while ipratropium has low systemic bioavailability.
DistributionBoth agents distribute into the lungs and systemic circulation. Levosalbutamol is widely distributed, and ipratropium does not readily cross the blood-brain barrier due to its quaternary ammonium structure. Protein binding is minimal for both.
Protein BindingLevosalbutamol: approximately 10-20% bound to plasma proteins. Ipratropium: less than 20% bound to plasma proteins.
MetabolismLevosalbutamol is metabolized in the liver primarily by sulfation, with minor glucuronidation. Ipratropium is minimally metabolized; the majority is excreted unchanged.
Half-LifeLevosalbutamol: approximately 3-4 hours. Ipratropium: approximately 2 hours.
ExcretionLevosalbutamol and its metabolites are excreted mainly in urine. Ipratropium is excreted primarily unchanged in the urine and feces.
BioavailabilityLevosalbutamol: systemic bioavailability via inhalation is about 10-20% of the dose. Ipratropium: systemic bioavailability is low, approximately 2-5%.
Onset of ActionBronchodilation typically begins within 5-15 minutes after inhalation.
Peak Plasma TimeLevosalbutamol: peak plasma levels occur within 30 minutes. Ipratropium: peak plasma levels occur within 1-2 hours.
Duration of ActionBronchodilation lasts for approximately 4-6 hours, allowing for dosing every 6 hours as needed.

How It Works

This medicine combines two bronchodilators with different mechanisms. Levosalbutamol selectively stimulates beta-2 adrenergic receptors in the airways, leading to relaxation of bronchial smooth muscle and rapid bronchodilation. Ipratropium blocks muscarinic acetylcholine receptors, reducing vagal tone and preventing bronchoconstriction and mucus hypersecretion. The complementary actions provide enhanced and prolonged bronchodilation compared to either agent alone.

Mechanism Steps

1
Beta-2 receptor stimulation: Levosalbutamol binds to beta-2 adrenergic receptors on bronchial smooth muscle cells, activating adenylate cyclase and increasing cyclic AMP levels.
2
Smooth muscle relaxation: Increased cyclic AMP leads to relaxation of bronchial smooth muscle, resulting in bronchodilation and improved airflow.
3
Muscarinic receptor blockade: Ipratropium competitively inhibits acetylcholine at muscarinic receptors on bronchial smooth muscle and submucosal glands.
4
Reduced bronchoconstriction and secretions: Blockade of muscarinic receptors prevents vagally mediated bronchoconstriction and decreases mucus secretion, further improving airway patency.

💡 How to Take ipradin ls 50mcg/20mcg inhaler

Strength: Inhaler containing levosalbutamol 50 mcg and ipratropium 20 mcg per puff.

1Remove the cap and shake the inhaler well before each use.
2Breathe out gently to empty your lungs.
3Place the mouthpiece in your mouth and close your lips around it.
4Press the canister down while breathing in slowly and deeply.
5Hold your breath for about 10 seconds, then breathe out slowly.
6Wait at least 30 seconds between puffs if two puffs are prescribed.
7Rinse your mouth with water after use to prevent oral thrush.
8Clean the inhaler weekly as per instructions.

Dosage Information

Adult DosageThe usual adult dose is 2 puffs inhaled every 6 hours as needed for maintenance therapy. The maximum recommended dose is 12 puffs per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing.
Elderly DosageElderly patients may be more sensitive to the cardiovascular and anticholinergic effects of this medicine. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function.
Renal ImpairmentNo specific dose adjustment is established for renal impairment. Use with caution in patients with severe renal impairment and monitor for systemic effects.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution in patients with severe hepatic impairment.
Maximum Daily Dose12 puffs per day (each puff contains levosalbutamol 50 mcg and ipratropium 20 mcg).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific food restrictions
This medicine is inhaled, so food does not affect its absorption.
Caffeine
Limit
May increase nervousness and tremor.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ipradin ls 50mcg/20mcg inhaler

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Tremor (Common (5-10%))
Usually transient. Reduce caffeine intake. Consult doctor if bothersome.
Nervousness (Common (5-10%))
May diminish with continued use. Consult doctor if it interferes with daily activities.
Throat irritation (Common (5-10%))
Rinse mouth after use. Consult doctor if persists.
Dry mouth (Common (5-10%))
Stay hydrated, chew sugar-free gum. Consult doctor if severe.

🚨 Serious Side Effects

Paradoxical bronchospasm (Rare (<0.1%))
Stop use immediately and seek emergency medical help if breathing worsens after inhalation.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Cardiac arrhythmias (Rare (<0.1%))
Report palpitations, chest pain, or fainting to your doctor immediately.
Urinary retention (Rare (<0.1%))
Consult doctor if you have difficulty urinating.

⚠️ Rare Side Effects

Blurred vision
Avoid spraying into eyes. Consult doctor if vision changes occur.
Hypokalemia
Monitor potassium levels if on high doses or other medications. Consult doctor.
Hyperglycemia
Monitor blood sugar if diabetic. Consult doctor if levels rise.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Tiotropium Major
Furosemide Moderate
Thiazide diuretics Moderate
Systemic corticosteroids Moderate
Digoxin Moderate
Theophylline Minor
Levodopa Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants
  • Other anticholinergic drugs (e.g., tiotropium, oxybutynin)

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide, thiazides)
  • Corticosteroids (systemic)
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects. It is advisable to limit or avoid alcohol while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levosalbutamol, ipratropium, or any component of the formulation","Severe cardiovascular disease or uncontrolled arrhythmias","Acute bronchospasm requiring immediate rescue therapy (use a short-acting bronchodilator instead)","Narrow-angle glaucoma (due to anticholinergic effects)","Urinary retention or bladder neck obstruction"]

⚠️ Warnings & Precautions

["Do not use for acute bronchospasm; keep a short-acting rescue inhaler available.","Rinse mouth after inhalation to prevent oral thrush.","Avoid contact with eyes; may cause blurred vision or acute glaucoma.","Use with caution in patients with cardiovascular disorders, especially arrhythmias.","Monitor potassium levels in patients on high doses or concomitant diuretics.","May cause paradoxical bronchospasm; discontinue and seek medical help if it occurs.","Use with caution in patients with diabetes, hyperthyroidism, or seizure disorders.","Do not exceed the prescribed dose; serious cardiovascular effects may occur."]

🤱 Lactation Safety

It is not known whether levosalbutamol and ipratropium are excreted in human breast milk. Caution is advised when used by breastfeeding mothers. Consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose may cause tachycardia, tremor, palpitations, hypertension, and hypokalemia. In case of suspected overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Use this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Rinse your mouth with water after each inhalation to reduce the risk of oral thrush. Avoid spraying into the eyes as it may cause blurred vision or irritation. Keep a short-acting rescue inhaler with you at all times for sudden breathing difficulty. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or glaucoma. Do not stop this medicine abruptly without consulting your doctor. Store the inhaler properly and check the dose counter regularly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular and anticholinergic effects of this medicine. Use with caution and monitor for side effects such as urinary retention, confusion, and arrhythmias.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. The safety of this combination during pregnancy is not fully established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are using this medicine before surgery. It may interact with certain anesthetic agents and affect heart rate and blood pressure.

🦷 Dental Procedures

Inform your dentist if you are using this medicine, as it may cause dry mouth and increase the risk of dental caries. Rinse your mouth after use and maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Maintain a healthy weight to reduce strain on your lungs.
😴
Practice breathing exercises like pursed-lip breathing.
💧
Get vaccinated against influenza and pneumonia.
🧘
Use air purifiers indoors to reduce allergens.
🌞
Stay hydrated to keep mucus thin.

🏋️ Exercise Considerations

Exercise can trigger bronchospasm in some patients. Use your rescue inhaler before exercise if advised by your doctor. Warm up slowly and avoid exercising in cold, dry air. If you experience shortness of breath, stop and rest.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Include omega-3 fatty acids from fish or flaxseed.
Limit processed foods and excess salt.
Stay well hydrated.
Avoid foods that trigger allergies.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or blurred vision in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most daily activities when used as prescribed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Abrupt discontinuation can lead to worsening of asthma or COPD symptoms.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when used as prescribed. Regular monitoring of heart rate, blood pressure, and potassium levels may be required. Overuse can lead to reduced effectiveness and increased risk of cardiovascular side effects. Periodic review by a doctor is recommended to assess control of asthma or COPD and to adjust therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled corticosteroids

Can be used as controller therapy for asthma, often in combination with bronchodilators.

Evidence: Well-established
Long-acting beta-agonists (LABAs)

Used for maintenance therapy in asthma and COPD, but not as rescue medication.

Evidence: Well-established
Pulmonary rehabilitation

Exercise and education program for COPD patients to improve quality of life.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Patients with chronic respiratory diseases should receive annual influenza vaccination and pneumococcal vaccination as per guidelines. These vaccines can reduce the risk of exacerbations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not puncture or incinerate the canister

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry your inhaler in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid extreme temperatures in checked baggage. If traveling across time zones, adjust your dosing schedule as advised by your doctor. Ensure you have enough supply for the entire trip. Check customs regulations for carrying prescription medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with COPD
He was prescribed this inhaler for maintenance therapy. Initially, he used it only when he felt breathless, but his doctor explained it should be used regularly. After using it twice daily for a month, his breathing improved significantly and he could walk longer distances without stopping.
💡 Lesson: Regular use as prescribed is key to controlling COPD symptoms and improving quality of life.
👤 A 30-year-old woman with asthma
She experienced hand tremors after starting this inhaler. Her doctor reassured her that it was a common side effect and would diminish over time. She was advised to rinse her mouth after each use and to avoid caffeine. Within two weeks, the tremors reduced, and her asthma was well controlled.
💡 Lesson: Common side effects like tremors are usually temporary and can be managed with simple measures.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 5-15 minutes after inhalation, with effects lasting 4-6 hours.

Q: Can I use this inhaler during an asthma attack?

A: No, this medicine is for maintenance therapy. For acute attacks, use a short-acting rescue inhaler like salbutamol.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use.

Q: Can I use this medicine if I have glaucoma?

A: This medicine is contraindicated in narrow-angle glaucoma due to anticholinergic effects. Consult your doctor for alternatives.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ipradin ls 50mcg/20mcg inhaler

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This inhaler can be used for immediate relief of an asthma attack.
    Fact: This medicine is for maintenance therapy only. For acute attacks, use a short-acting rescue inhaler like salbutamol.
  • Myth: Using inhalers is addictive.
    Fact: Inhalers are not addictive. They are essential for managing chronic respiratory conditions.
  • Myth: You can stop using this inhaler once you feel better.
    Fact: Do not stop without consulting your doctor. Stopping suddenly can worsen your condition.

🔄 Alternative Options

Generic Alternatives

  • Levosalbutamol + Ipratropium inhaler (generic)

Brand Alternatives

  • Iprasure Inhaler
  • Levolin-I Inhaler
  • Duolin Inhaler

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Levosalbutamol + Ipratropium","onset":"5-15 minutes","duration":"4-6 hours","indication":"Asthma, COPD"},{"medicine":"Salbutamol + Ipratropium","active_ingredients":"Salbutamol + Ipratropium","onset":"5-15 minutes","duration":"4-6 hours","indication":"Asthma, COPD"},{"medicine":"Levosalbutamol alone","active_ingredients":"Levosalbutamol","onset":"5-15 minutes","duration":"4-6 hours","indication":"Asthma, COPD"}]

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