ionozem 30mg tablet - Diltiazem (30mg) medicine

Altiazem 30mg Tablet: Complete Medicine Guide

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🏭 Pfizer Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain that does not go away with rest or usual medication
  • Difficulty breathing or shortness of breath
  • Swelling of the face, lips, tongue, or throat
  • Very slow or irregular heartbeat
  • Fainting or loss of consciousness
  • Yellowing of the skin or eyes, dark urine, or severe abdominal pain
  • Severe dizziness or lightheadedness that does not improve

If experiencing severe symptoms, call emergency services immediately.

What is ionozem 30mg tablet used for?

This medicine contains diltiazem 30 mg, a calcium channel blocker used to treat high blood pressure and prevent angina. It works by relaxing blood vessels and reducing the heart's workload. It is a prescription medicine and should be taken exactly as directed by your doctor.

  • Generic Name: Diltiazem (30mg)
  • Manufacturer: Pfizer Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ionozem 30mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डिल्टियाज़ेम 30 मिलीग्राम की एक टैबलेट है, जिसका उपयोग उच्च रक्तचाप और एंजाइना (सीने में दर्द) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर और हृदय पर दबाव कम करके काम करती है। यह एक प्रिस्क्रिप्शन दवा है और इसे डॉक्टर के निर्देशानुसार ही लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, पैरों में सूजन, और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, बहुत धीमी हृदय गति, या पीलिया जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को अचानक बंद न करें, क्योंकि इससे एंजाइना बिगड़ सकता है। इसे डॉक्टर के बताए अनुसार ही लें। अंगूर का जूस पीने से बचें, क्योंकि इससे दवा का स्तर बढ़ सकता है। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ionozem 30mg tablet Uses & Benefits

[{"condition":"Chronic stable angina","description":"This medicine helps to prevent chest pain by relaxing blood vessels and reducing the heart's workload, improving blood flow to the heart muscle.","evidence":"Well-established"},{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure by relaxing blood vessels, which reduces the pressure against which the heart must pump.","evidence":"Well-established"},{"condition":"Vasospastic angina (Prinzmetal's angina)","description":"This medicine is effective in treating chest pain caused by spasms of the coronary arteries.","evidence":"Well-established"},{"condition":"Atrial fibrillation or atrial flutter","description":"This medicine may be used to control heart rate in certain patients with these irregular heart rhythms.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to help prevent migraines, though it is not a first-line treatment.","evidence":"Limited"},{"condition":"Raynaud's phenomenon","description":"Occasionally used off-label to improve blood flow to the fingers and toes in people with this condition.","evidence":"Limited"}]

Primary treatment for: Chronic stable angina

Also treats: Hypertension, Vasospastic angina, Atrial fibrillation, Atrial flutter

📋 Drug Information

Generic Name(s)Diltiazem (30mg)
Brand Nameionozem 30mg tablet
ManufacturerPfizer Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Nondihydropyridines
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels in your body.
2
Do not stop taking this medicine suddenly without consulting your doctor, as it can worsen your heart condition.
3
Avoid drinking grapefruit juice while taking this medicine, as it can increase the risk of side effects.
4
Monitor your blood pressure and heart rate regularly, and report any significant changes to your doctor.
5
If you experience dizziness or lightheadedness, rise slowly from sitting or lying positions.
6
Inform your doctor about all other medicines you are taking, including over-the-counter drugs and supplements.
7
Keep a record of your angina attacks and share it with your doctor to help adjust your treatment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chest pain (angina)
This medicine is commonly prescribed to prevent angina.
Likely Use
✅
High blood pressure
This medicine is used to treat hypertension.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment; it may cause headache as a side effect.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. However, it undergoes significant first-pass metabolism in the liver, which reduces the amount that reaches the bloodstream unchanged. Food does not significantly affect the extent of absorption but may slightly delay it.
DistributionThis medicine is widely distributed throughout the body tissues. It is highly bound to plasma proteins, primarily albumin. It can cross the placenta and is excreted in breast milk in small amounts.
Protein BindingApproximately 70-80% bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by cytochrome P450 enzymes, particularly CYP3A4. It undergoes first-pass metabolism, and its metabolites are pharmacologically less active than the parent drug. The metabolism can be affected by other medicines that inhibit or induce CYP3A4.
Half-LifeThe elimination half-life of this medicine is approximately 3 to 4.5 hours, but it may be longer in elderly patients and those with liver impairment.
ExcretionThis medicine and its metabolites are primarily excreted in the urine and feces. About 60% is excreted in urine and 35% in feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 40% due to first-pass metabolism.
Onset of ActionWhen taken orally, this medicine begins to lower blood pressure and heart rate within 30 to 60 minutes, but the full effect may take several days to develop with regular use.
Peak Plasma TimePeak plasma concentrations are reached approximately 2 to 4 hours after oral administration.
Duration of ActionThe blood pressure-lowering effect of a single dose lasts about 6 to 8 hours, but with regular dosing, the effect is maintained throughout the day. For angina prevention, the effect may last longer with sustained-release formulations.

How It Works

This medicine works by blocking the entry of calcium ions into the smooth muscle cells of the blood vessels and the heart. Calcium is essential for these muscles to contract. By reducing calcium entry, this medicine causes the blood vessels to relax and widen, which lowers blood pressure and improves blood flow. In the heart, it reduces the force of contraction and slows the heart rate, which decreases the heart's demand for oxygen. This helps to relieve and prevent angina. Additionally, it dilates the coronary arteries, improving oxygen supply to the heart muscle.

Mechanism Steps

1
Blockade of L-type calcium channels: This medicine binds to and blocks L-type calcium channels in the membranes of smooth muscle and heart muscle cells.
2
Reduced calcium entry: As a result of the blockade, fewer calcium ions enter the cells during excitation.
3
Vasodilation: Lower calcium levels in vascular smooth muscle cells cause them to relax, leading to widening of blood vessels and reduced blood pressure.
4
Decreased cardiac workload: In the heart, reduced calcium entry leads to a slower heart rate and decreased force of contraction, lowering the heart's oxygen demand.
5
Improved oxygen balance: The combined effects improve blood flow to the heart muscle and reduce its oxygen needs, which helps to prevent angina.

💡 How to Take ionozem 30mg tablet

Strength: This medicine is available as an immediate-release oral tablet containing 30 mg of diltiazem.

1Take this medicine by mouth with or without food, but taking it with food may reduce stomach upset.
2Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet unless your doctor advises otherwise.
3Take it at the same times each day to maintain consistent levels in your body.
4If you are taking other medicines, ask your doctor or pharmacist about the best timing to avoid interactions.
5Do not stop taking this medicine abruptly without consulting your doctor.

Dosage Information

Adult DosageThe usual starting dose of this medicine for adults is 30 mg taken three to four times a day for immediate-release tablets. Your doctor may gradually increase the dose based on your response and tolerance. For high blood pressure, the dose may range from 120 mg to 360 mg per day in divided doses. For angina, the dose is often 30 mg to 120 mg three to four times daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change your dose without consulting your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and low blood pressure. The starting dose may be lower, and dose adjustments should be made cautiously. Regular monitoring of blood pressure and heart rate is recommended.
Renal ImpairmentNo specific dose adjustment is usually required for mild to moderate kidney impairment. In severe kidney impairment, use with caution and monitor closely. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with liver impairment, the dose of this medicine should be reduced and titrated slowly, as the medicine is extensively metabolized by the liver. Regular monitoring of liver function is advised.
Maximum Daily DoseThe maximum recommended daily dose for immediate-release tablets is 360 mg per day, but this may vary based on the condition and individual response. Always follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels and risk of side effects.
High-fat meals
No specific restriction
May slightly delay absorption but not clinically significant.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ionozem 30mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you. Rise slowly from sitting or lying positions.
Flushing (Common (5-10%))
This is usually temporary and harmless. If it bothers you, talk to your doctor.
Swelling of ankles or feet (peripheral edema) (Common (5-10%))
Elevate your legs when sitting. If swelling is severe or persistent, contact your doctor.
Nausea (Common (5-10%))
Take the medicine with food to reduce nausea. If it continues, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Very slow heart rate (bradycardia) (Rare (<0.1%))
Contact your doctor right away if you feel faint, extremely tired, or have a very slow pulse.
Heart block (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or fainting.
Liver problems (hepatotoxicity) (Rare (<0.1%))
Report yellowing of the skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Severe low blood pressure (hypotension) (Rare (<0.1%))
If you feel dizzy, faint, or have blurred vision, lie down and seek medical help.

⚠️ Rare Side Effects

Gum hyperplasia
Maintain good oral hygiene and consult your dentist if you notice gum swelling.
Photosensitivity
Use sunscreen and protective clothing when outdoors.
Elevated liver enzymes
Your doctor may monitor your liver function with blood tests.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Beta-blockers Major
Digoxin Major
CYP3A4 inhibitors Major
CYP3A4 inducers Major
Statins Major
Other antihypertensives Moderate
Cyclosporine Moderate
Carbamazepine Moderate
Midazolam Moderate
Antacids Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol, metoprolol)
  • Digoxin
  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
  • Statins (e.g., simvastatin, atorvastatin)

⚡ Moderate Interactions

  • Other antihypertensive medicines
  • Cyclosporine
  • Carbamazepine
  • Midazolam

🍷 Alcohol Interaction

Alcohol can increase the blood pressure-lowering effect of this medicine and may cause excessive dizziness, lightheadedness, or fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe low blood pressure (systolic BP < 90 mmHg)","Severe heart failure","Second- or third-degree heart block without a pacemaker","Sick sinus syndrome without a pacemaker","Severe bradycardia (heart rate < 40 beats per minute)","Known hypersensitivity to diltiazem or any component of the formulation","Acute myocardial infarction with pulmonary congestion"]

⚠️ Warnings & Precautions

["Do not stop taking this medicine suddenly, as it can worsen angina or lead to a heart attack.","Use with caution in patients with liver or kidney impairment; dose adjustment may be needed.","May cause dizziness or lightheadedness; avoid driving or operating machinery until you know how it affects you.","Avoid grapefruit juice while taking this medicine.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","This medicine may interact with many other medicines; always provide a complete list of your medications to your doctor.","Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and low blood pressure."]

🤱 Lactation Safety

This medicine is excreted in breast milk in small amounts. It is generally considered safe for breastfeeding mothers, but you should consult your doctor to weigh the benefits and risks. Monitor your baby for any unusual symptoms such as drowsiness or poor feeding.

💊 Overdose Management

Overdose of this medicine can cause severe low blood pressure, very slow heart rate, heart block, and even cardiac arrest. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, medications to raise blood pressure, and in severe cases, temporary pacing or use of antidotes like calcium gluconate. Do not try to treat yourself.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.

Additional Safety Advice

General Safety

Before you start this medicine, tell your doctor if you have any heart, liver, or kidney problems, or if you have ever had an allergic reaction to any medicine. Do not stop taking this medicine suddenly, because stopping abruptly can cause your angina to worsen or lead to a heart attack. Take this medicine exactly as prescribed, and do not change the dose without talking to your doctor first. Avoid drinking grapefruit juice while taking this medicine, as it can increase the amount of medicine in your blood and raise the risk of side effects. Be careful when standing up quickly, as this medicine can cause dizziness or lightheadedness. If you feel dizzy or faint, sit or lie down and inform your doctor. This medicine may interact with many other medicines, including those for blood pressure, cholesterol, and infections, so always give your doctor a complete list of everything you take. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of the reach of children and store it as directed on the label.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering and heart rate-slowing effects of this medicine. Start with a lower dose and monitor closely for dizziness, falls, and low blood pressure. Regular check-ups are important.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Your doctor may switch you to a safer alternative if needed. Use effective contraception while taking this medicine unless otherwise advised.

🏥 Post-Surgery Considerations

After surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and other medications used during surgery. Your doctor may adjust the dose or temporarily stop it before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain local anesthetics or other medicines used in dentistry. Your dentist may need to consult your doctor.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Engage in regular low-impact exercise like walking or swimming, as advised by your doctor.
😴
Follow a heart-healthy diet low in salt and saturated fats.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep to support heart health.

🏋️ Exercise Considerations

This medicine may cause dizziness or lightheadedness, especially when you start treatment or change doses. Avoid strenuous exercise until you know how the medicine affects you. If you experience chest pain during exercise, stop and rest, and follow your doctor's advice for angina. Always warm up and cool down gradually.

🥗 Diet Recommendations

Include plenty of fruits, vegetables, and whole grains.
Choose lean proteins and healthy fats.
Limit salt intake to help control blood pressure.
Avoid grapefruit and grapefruit juice.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Most people can continue their normal work activities with some adjustments. Inform your employer if your job involves operating heavy machinery or driving.

🛑 When to Stop This Medicine

Do not stop taking this medicine on your own. Your doctor will decide when and how to stop it, usually by gradually reducing the dose. Stopping suddenly can cause worsening of angina or a heart attack. If you experience serious side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups should include blood pressure, heart rate, and liver function tests. Some patients may develop tolerance or require dose adjustments over time. It is important to continue lifestyle modifications such as a healthy diet and exercise to manage your condition effectively. Do not stop the medicine without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress management can help control blood pressure and angina.

Evidence: Well-established
Other classes of anti-anginal medicines

Beta-blockers, nitrates, and other calcium channel blockers may be alternatives.

Evidence: Well-established
Procedures like angioplasty or bypass surgery

For severe coronary artery disease, invasive procedures may be needed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, consult your doctor about how to adjust your dosing schedule. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough supply for your entire trip, plus a little extra in case of delays.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of high blood pressure and angina
He was prescribed this medicine 30 mg three times a day. Initially, he experienced mild dizziness, which improved after a week. He noticed fewer angina attacks and better blood pressure control. He learned to take the medicine with food to avoid stomach upset and to avoid grapefruit juice.
💡 Lesson: Consistent use and lifestyle modifications, along with avoiding grapefruit juice, can improve outcomes and reduce side effects.
👤 A 62-year-old woman with hypertension and atrial fibrillation
She was started on this medicine to control her heart rate. She was advised to monitor her pulse daily. After a few weeks, her heart rate was well controlled, and she felt more energetic. She was reminded not to stop the medicine abruptly.
💡 Lesson: Regular monitoring and adherence to prescribed therapy are key to managing chronic heart conditions safely.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts to lower blood pressure and heart rate within 30 to 60 minutes, but the full effect may take several days of regular use.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop taking this medicine without consulting your doctor. Stopping suddenly can worsen your condition.

Q: Is it safe to take this medicine during pregnancy?

A: This medicine should be used during pregnancy only if clearly needed. Consult your doctor to weigh the benefits and risks.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ionozem 30mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms, and stopping this medicine can cause a dangerous rise in blood pressure. Always consult your doctor before stopping.
  • Myth: This medicine is a blood thinner.
    Fact: This medicine is not a blood thinner. It is a calcium channel blocker that relaxes blood vessels and reduces heart workload.
  • Myth: Grapefruit juice is safe with this medicine.
    Fact: Grapefruit juice can increase the levels of this medicine in your blood and lead to side effects. It is best to avoid it.

🔄 Alternative Options

Generic Alternatives

  • Diltiazem 30 mg tablet

Brand Alternatives

  • Altiazem 30mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Diltiazem","class":"Calcium channel blocker","primary_use":"Angina, hypertension","common_side_effects":"Headache, dizziness, edema"},{"medicine":"Amlodipine","class":"Calcium channel blocker","primary_use":"Hypertension, angina","common_side_effects":"Edema, dizziness, flushing"},{"medicine":"Verapamil","class":"Calcium channel blocker","primary_use":"Hypertension, angina, arrhythmias","common_side_effects":"Constipation, dizziness, headache"}]

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