amlogard 5mg tablet - Amlodipine (5mg) medicine

amlogard 5mg tablet

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🏭 Pfizer Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is amlogard 5mg tablet used for?

This medicine contains Amlodipine (5mg) and is used to treat CARDIAC. Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, leading to vasodilation. Always consult your doctor before use.

  • Generic Name: Amlodipine
  • Manufacturer: Pfizer Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 amlogard 5mg tablet Uses & Benefits

Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina).

Off-label uses: Raynaud's phenomenon, migraine prophylaxis, high-altitude pulmonary edema.

📋 Drug Information

Generic Name(s)Amlodipine
Brand NameAmlokind 5 Tablet
ManufacturerPfizer Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Dihydropyridines (DHP)
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed after oral administration with peak plasma concentrations achieved within 6-12 hours.
DistributionExtensively distributed with a large volume of distribution (about 21 L/kg).
Protein BindingApproximately 93% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP3A4 isoenzyme to inactive metabolites.
Half-Life30-50 hours (terminal elimination half-life).
ExcretionPrimarily excreted as metabolites in urine (about 60%) and feces (20-25%).
Bioavailability64-90% (oral bioavailability).
Onset of ActionGradual onset; antihypertensive effect seen within 2-4 hours.
Peak Plasma Time6-12 hours.
Duration of Action24 hours (once-daily dosing).

How It Works

Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance.

Mechanism Steps

1Binds to L-type calcium channels in vascular smooth muscle and cardiac myocytes.
2Inhibits calcium ion influx during depolarization.
3Reduces intracellular calcium concentration.
4Causes relaxation of vascular smooth muscle (vasodilation).
5Decreases peripheral vascular resistance and blood pressure.
6Increases coronary blood flow and reduces myocardial oxygen demand.

💡 How to Take amlogard 5mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of amlogard 5mg tablet

✅ Common Side Effects

Edema (peripheral)
Dizziness
Flushing
Palpitations
Fatigue
Nausea

🚨 Serious Side Effects

Severe hypotension
Myocardial infarction (rare)
Hepatotoxicity (rare)
Stevens-Johnson syndrome (rare)

⚠️ Rare Side Effects

Gingival hyperplasia
Gynecomastia
Leukopenia
Vasculitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
CYP3A4 inhibitors Major Increased amlodipine exposure, risk of toxicity
CYP3A4 inducers Major Decreased amlodipine efficacy
Simvastatin Major Increased risk of myopathy/rhabdomyolysis
Grapefruit juice Moderate Increased amlodipine levels
Diltiazem Moderate Increased amlodipine levels
Clarithromycin Moderate Increased amlodipine levels
Antacids Minor Slight decrease in amlodipine absorption
Sildenafil Minor Additive hypotensive effect

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)
  • Simvastatin

⚡ Moderate Interactions

  • Grapefruit juice
  • Diltiazem
  • Clarithromycin

🍷 Alcohol Interaction

Alcohol may potentiate the hypotensive effect.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to amlodipine or dihydropyridines, severe hypotension, cardiogenic shock.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Gastric lavage, activated charcoal, supportive care; calcium gluconate may be beneficial.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

🔄 Substitutes for amlogard 5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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