Avekoud Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of face, lips, tongue, or throat
- Severe dizziness or fainting
- Irregular or rapid heartbeat
- Blood in sputum or severe chest pain
- High fever with productive cough
- Cough lasting more than 7 days without improvement
If experiencing severe symptoms, call emergency services immediately.
What is intriz-plus tablet used for?
This medicine is a combination of Ambroxol (a mucolytic) and Levocetirizine (an antihistamine) used to treat productive cough with allergic symptoms. It works by thinning mucus and blocking histamine. It is usually taken once daily at bedtime. Common side effects include drowsiness and dry mouth. Avoid alcohol and driving until you know how it affects you.
- Generic Name: Ambroxol (60mg) + Levocetirizine (2.5mg)
- Manufacturer: Invision Medi Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 intriz-plus tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एम्ब्रोक्सोल और लेवोसेटिरिज़िन का संयोजन है। इसका उपयोग बलगम वाली खांसी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना और आंखों में पानी आना के इलाज में किया जाता है। यह बलगम को पतला करके खांसी को आसान बनाती है और एलर्जी को कम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, थकान और पेट में हल्की परेशानी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई या दिल की धड़कन अनियमित होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से मात्रा न बढ़ाएं। दवा लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 intriz-plus tablet Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin mucus in the airways, making it easier to cough out.","evidence":"Well-established"},{"condition":"Allergic rhinitis with cough","description":"Reduces allergic symptoms such as runny nose, sneezing, and itching, which can help decrease postnasal drip and associated cough.","evidence":"Moderate"},{"condition":"Acute bronchitis","description":"Provides symptomatic relief from cough and mucus production in acute bronchitis.","evidence":"Moderate"},{"condition":"Chronic bronchitis","description":"May help in managing chronic bronchitis symptoms by improving mucus clearance.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to relieve nasal congestion and postnasal drip associated with sinusitis.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally prescribed to help clear middle ear fluid, but evidence is weak.","evidence":"Limited"}]
Primary treatment for: Productive cough with allergic rhinitis
Also treats: Acute bronchitis, Chronic bronchitis, Allergic rhinitis
📋 Drug Information
| Generic Name(s) | Ambroxol (60mg) + Levocetirizine (2.5mg) |
| Brand Name | intriz-plus tablet |
| Manufacturer | Invision Medi Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Ambroxol is a mucolytic agent that increases serous bronchial secretion, reduces mucus viscosity, and promotes ciliary clearance, making it easier to expel mucus. Levocetirizine is a selective peripheral H1-receptor antagonist that blocks histamine, reducing allergic symptoms such as sneezing, rhinorrhea, and itching. Together, they address both the mucus component and the allergic component of respiratory conditions.
Mechanism Steps
💡 How to Take intriz-plus tablet
Strength: Tablet containing Ambroxol 60 mg and Levocetirizine 2.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily, preferably at bedtime, or as directed by your doctor. The dose may be adjusted based on your condition and kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially drowsiness. Dose adjustment may be necessary based on kidney function. Consult your doctor. |
| Renal Impairment | Dose adjustment is required in patients with kidney impairment. In severe renal impairment (creatinine clearance <10 mL/min), this medicine is contraindicated. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and consult your doctor. |
| Maximum Daily Dose | One tablet per day. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of intriz-plus tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| MAO inhibitors | Major | |
| Tricyclic antidepressants | Moderate | |
| Ritonavir | Moderate | |
| Theophylline | Minor | |
| Erythromycin | Minor | |
| Cimetidine | Minor | |
| Ketoconazole | Minor |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- MAO inhibitors
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- Ritonavir
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness and impair your ability to drive or operate machinery. It may also worsen dizziness and reduce alertness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Ambroxol, Levocetirizine, or any component of the formulation.","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with kidney or liver disease.","Do not use for a dry cough or for cough lasting more than 7 days without medical advice.","Not recommended for children under 6 years.","Elderly patients may be more sensitive to side effects."]
🤱 Lactation Safety
Not established from the available information. It is not known whether Ambroxol or Levocetirizine pass into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe drowsiness, agitation, confusion, rapid heartbeat, or difficulty breathing. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol while taking this medicine, as it can increase drowsiness and impair alertness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for a dry cough or for a cough that lasts more than 7 days without consulting a doctor. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the sedative effects of this medicine. Dose adjustment may be needed based on kidney function. Use with caution.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and affect oral health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is best to take it at bedtime. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, or if you experience severe side effects such as allergic reactions, irregular heartbeat, or extreme drowsiness.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance or increased side effects. Regular monitoring of kidney and liver function may be advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion.
Evidence: Well-establishedCan help clear nasal passages and reduce allergy symptoms.
Evidence: ModerateReducing exposure to allergens can decrease the need for medication.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction with vaccines is established. However, if you are scheduled for vaccination, inform your doctor about this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, continue taking it at the same interval as prescribed. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief from cough and allergy symptoms within 1-3 days, but full effect may take up to a week.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.
A: Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for intriz-plus tablet
View AllAlternative brands with exact same active ingredient:
-
comcet a 2.5mg/60mg tabletLifecom Pharmaceuticals Pvt Ltd ₹20.00 65.5% CHEAPER
-
cyptic 60mg/2.5mg/500mg/5mg tabletPax Healthcare ₹32.81 43.5% CHEAPER
-
elzik tabletAden Healthcare ₹32.81 43.5% CHEAPER
-
histalev a plus tabletAltruist Pharmacia Pvt Ltd ₹32.81 43.5% CHEAPER
-
kargip tabletAcinom Healthcare ₹32.81 43.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for productive cough with mucus and allergic symptoms. It is not effective for dry cough or cough due to other causes. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol increases drowsiness and impairs alertness. Avoid alcohol while taking this medicine. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: Complete the course as prescribed by your doctor to prevent recurrence of symptoms.
🔄 Alternative Options
Generic Alternatives
- Ambroxol + Levocetirizine combination generics available
Brand Alternatives
- Avekoud Tablet