Eptiflo Injection: A Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or uncontrolled bleeding from any site
- Blood in urine or black, tarry stools
- Sudden severe headache, confusion, or vision changes
- Difficulty breathing or swelling of face, lips, or throat
- Chest pain or palpitations
- Decreased urine output or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is interiglin 20mg injection used for?
This medicine is an intravenous antiplatelet medicine used in hospitals to prevent blood clots in patients with acute coronary syndrome or those undergoing angioplasty. It works by blocking platelet aggregation.
- Generic Name: Eptifibatide (20mg)
- Manufacturer: Fulford India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 interiglin 20mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक इंजेक्शन है जिसका उपयोग अस्पताल में दिल के दौरे और एंजियोप्लास्टी के दौरान खून के थक्के बनने से रोकने के लिए किया जाता है। यह खून को पतला करने वाली दवाओं की श्रेणी में आती है और इसे केवल डॉक्टर या नर्स द्वारा नस के माध्यम से दिया जाता है।
साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभावों में रक्तस्राव, चक्कर आना, मतली और सिरदर्द शामिल हैं। गंभीर रक्तस्राव दुर्लभ है लेकिन तुरंत डॉक्टर को बताना चाहिए।
सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर की देखरेख में दी जाती है। इसे घर पर स्वयं न लें। उपचार के दौरान किसी भी असामान्य रक्तस्राव या एलर्जी के लक्षण की सूचना तुरंत डॉक्टर को दें।
💊 interiglin 20mg injection Uses & Benefits
[{"condition":"Acute Coronary Syndrome (ACS)","description":"Used in patients with unstable angina or non-ST-elevation myocardial infarction to reduce the risk of heart attack and death when used with other medicines.","evidence":"Well-established"},{"condition":"Percutaneous Coronary Intervention (PCI)","description":"Administered during angioplasty and stent placement to prevent blood clots from forming in the coronary arteries.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of thrombotic complications in other vascular procedures","description":"Sometimes used off-label during carotid stenting or peripheral vascular interventions, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Acute Coronary Syndrome
Also treats: Percutaneous Coronary Intervention
📋 Drug Information
| Generic Name(s) | Eptifibatide (20mg) |
| Brand Name | interiglin 20mg injection |
| Manufacturer | Fulford India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Glycoprotein IIb/IIIa inhibitors |
| Route of Administration | Parenteral (intravenous) |
| Storage | Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Keep in the original carton until use. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking the glycoprotein IIb/IIIa receptor on the surface of platelets. This receptor is the final common pathway for platelet aggregation, meaning that when it is blocked, platelets cannot stick together to form a clot. By preventing platelet clumping, this medicine reduces the formation of dangerous blood clots in the coronary arteries.
Mechanism Steps
💡 How to Take interiglin 20mg injection
Strength: Injection: 20 mg
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the patient's weight, kidney function, and the specific clinical situation. It is typically given as an intravenous bolus followed by a continuous infusion. The dose must be adjusted for patients with renal impairment. Do not attempt to calculate or administer this medicine without medical supervision. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function and are at higher risk of bleeding. Dose adjustment may be necessary based on renal function. Close monitoring is recommended. |
| Renal Impairment | Dose adjustment is required for patients with moderate renal impairment (creatinine clearance 30-50 mL/min). This medicine is contraindicated in patients with severe renal impairment (creatinine clearance <30 mL/min) or on dialysis. |
| Hepatic Impairment | Not established from the available information. Use with caution in patients with hepatic impairment. |
| Maximum Daily Dose | Not established from the available information. The dose is determined by the prescribing clinician. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of interiglin 20mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Heparin | Major | |
| Warfarin | Major | |
| Alteplase | Major | |
| Ibuprofen | Major | |
| Clopidogrel | Moderate | |
| Apixaban | Moderate | |
| Rivaroxaban | Moderate | |
| Fluoxetine | Minor | |
| Omeprazole | Minor | |
| Aspirin | Moderate |
🚨 Major Interactions
- Other anticoagulants (e.g., heparin, warfarin)
- Thrombolytic agents (e.g., alteplase)
- NSAIDs (e.g., ibuprofen, naproxen)
⚡ Moderate Interactions
- Clopidogrel
- Direct oral anticoagulants (e.g., apixaban, rivaroxaban)
🍷 Alcohol Interaction
Alcohol may increase the risk of bleeding and should be avoided during treatment with this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active bleeding or bleeding diathesis","History of intracranial hemorrhage or stroke within 30 days","Severe uncontrolled hypertension","Major surgery within the past 6 weeks","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine should be used only by healthcare professionals in a hospital setting.","Bleeding risk is increased when used with other anticoagulants or antiplatelet agents.","Dose adjustment is required for patients with moderate renal impairment.","Monitor for signs of bleeding during and after infusion.","Thrombocytopenia can occur; monitor platelet counts.","Avoid use in patients with severe renal impairment."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may lead to severe bleeding. Treatment is supportive. If bleeding occurs, stop the infusion and manage bleeding as clinically indicated. There is no specific antidote, but platelet transfusion may be considered.
⏰ Missed Dose
This medicine is given by healthcare professionals in a controlled setting. Missed doses are not applicable for patients. If you miss an appointment for your infusion, contact your healthcare provider as soon as possible.
Additional Safety Advice
This medicine is given only by a doctor or nurse in a hospital or clinic setting. Do not attempt to use it at home. Before receiving this medicine, tell your doctor about all your medical conditions, especially any bleeding disorders, recent surgery, stroke, or kidney problems. Also inform them about all medicines you take, including blood thinners, pain relievers, and herbal supplements. While receiving this medicine, avoid activities that could cause injury or bleeding. Report any unusual bleeding, bruising, or signs of allergic reaction to your healthcare provider immediately. Your doctor will monitor your blood counts and kidney function during treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of bleeding and may have reduced kidney function. Dose adjustment and close monitoring are recommended.
🤰 Pregnancy Planning (TTC)
Not established from the available information. Consult your doctor if you are planning pregnancy or are pregnant.
🏥 Post-Surgery Considerations
This medicine increases bleeding risk. It is contraindicated in patients who have had major surgery within the past 6 weeks. Inform your surgeon if you have recently received this medicine.
🦷 Dental Procedures
Inform your dentist if you have recently received this medicine, as it may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that could cause injury or bleeding while receiving this medicine. Follow your doctor's advice on when to resume normal activities.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital, so it may require a short hospital stay. You should not drive or operate machinery immediately after treatment. Follow your doctor's advice on when you can resume work and normal activities.
🛑 When to Stop This Medicine
This medicine is stopped by your healthcare provider based on your clinical condition. Do not stop or adjust the infusion yourself. If you experience severe bleeding or other serious side effects, your doctor may stop the infusion.
📅 Long-Term Use Effects
This medicine is typically used for a short duration in the hospital. Long-term effects are not established from the available information. Your doctor will monitor your recovery and adjust treatment as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines like aspirin, clopidogrel, or ticagrelor may be used depending on the clinical situation.
Evidence: Well-establishedHeparin or bivalirudin may be used as alternatives or in combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccinations while receiving this medicine.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C.
❌ DON'T
Do not freeze.
✅ DO
Keep in the original carton to protect from light.
❌ DON'T
Do not use if the solution is discolored or contains particles.
✅ DO
Follow the manufacturer's instructions for storage.
❌ DON'T
Do not store at room temperature for extended periods.
✈️ Traveling with This Medicine
This medicine is given in a hospital setting, so travel advice is not applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Inform your doctor before traveling, especially if you have recently received this medicine.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working immediately after it is given intravenously.
A: No, this medicine is given only by healthcare professionals in a hospital setting.
A: Avoid activities that could cause injury or bleeding. Avoid alcohol and NSAIDs.
🤔 Common Patient Concerns
🔄 Substitutes for interiglin 20mg injection
View AllAlternative brands with exact same active ingredient:
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eptifab 20mg injectionAbbott ₹1,275.00 57.5% CHEAPER
-
eptibind 20mg injectionTorrent Pharmaceuticals Ltd ₹2,380.95 20.6% CHEAPER
-
eptide 20mg injectionSun Pharmaceutical Industries Ltd ₹2,471.51 17.6% CHEAPER
-
clotide 20mg injectionBiocon ₹2,500.00 16.7% CHEAPER
-
eptiba 20mg injectionIntas Pharmaceuticals Ltd ₹2,500.00 16.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home like a pill.
Fact: This medicine is given only by intravenous infusion in a hospital setting under medical supervision. - Myth: This medicine is a painkiller.
Fact: This medicine is an antiplatelet agent used to prevent blood clots, not to relieve pain.