Dutaxel 30mg Injection (Paclitaxel): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Fever, chills, or sore throat
- Unusual bleeding or bruising
- Severe abdominal pain
- Chest pain or palpitations
- Numbness or weakness in limbs
- Severe allergic reaction
If experiencing severe symptoms, call emergency services immediately.
What is intaxel 30mg injection used for?
This medicine contains paclitaxel, a chemotherapy drug used to treat breast, ovarian, lung, and other cancers. It works by stopping cancer cell division. It is given intravenously by a healthcare professional.
- Generic Name: Paclitaxel (30mg)
- Manufacturer: Fresenius Kabi India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 intaxel 30mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा पैक्लिटैक्सेल 30 मिलीग्राम इंजेक्शन के रूप में उपलब्ध है, जिसका उपयोग स्तन कैंसर, डिम्बग्रंथि कैंसर, फेफड़ों के कैंसर और कपोसी सारकोमा के इलाज के लिए किया जाता है। यह कीमोथेरेपी दवा है जो कैंसर कोशिकाओं के विभाजन को रोकती है। इसे डॉक्टर या नर्स द्वारा नस के माध्यम से दिया जाता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में बालों का झड़ना, मतली, उल्टी, दस्त, मुंह के छाले, जोड़ों और मांसपेशियों में दर्द, और हाथ-पैरों में सुन्नपन शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, रक्त कोशिकाओं की कमी, और हृदय संबंधी समस्याएं हो सकती हैं। किसी भी असामान्य लक्षण की तुरंत डॉक्टर को सूचना दें।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा अस्पताल या क्लिनिक में ही दी जानी चाहिए। उपचार के दौरान नियमित रक्त परीक्षण आवश्यक हैं। संक्रमण से बचने के लिए सावधानी बरतें। गर्भवती महिलाओं को यह दवा नहीं दी जानी चाहिए। स्तनपान कराने वाली महिलाओं को भी सावधानी बरतनी चाहिए।
💊 intaxel 30mg injection Uses & Benefits
[{"condition":"Breast cancer","description":"Used as part of combination chemotherapy for the treatment of early-stage and advanced breast cancer.","evidence":"Well-established"},{"condition":"Ovarian cancer","description":"Used as first-line and subsequent therapy for ovarian cancer, often in combination with platinum-based agents.","evidence":"Well-established"},{"condition":"Non-small cell lung cancer","description":"Used in combination with other chemotherapy drugs for advanced non-small cell lung cancer.","evidence":"Well-established"},{"condition":"Kaposi's sarcoma","description":"Used for the treatment of AIDS-related Kaposi's sarcoma.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Bladder cancer","description":"Sometimes used off-label in combination regimens for advanced bladder cancer.","evidence":"Limited"},{"condition":"Head and neck cancer","description":"Occasionally used off-label in combination therapy for head and neck cancers.","evidence":"Limited"}]
Primary treatment for: Cancer
Also treats: Breast cancer, Ovarian cancer, Non-small cell lung cancer, Kaposi's sarcoma
📋 Drug Information
| Generic Name(s) | Paclitaxel (30mg) |
| Brand Name | intaxel 30mg injection |
| Manufacturer | Fresenius Kabi India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimicrotubule agents- Taxanes |
| Route of Administration | Intravenous infusion |
| Storage | Store refrigerated at 2°C to 8°C. Protect from light. Do not freeze. |
| Shelf Life | Refer to the product label for shelf life. |
| WHO Guideline | Paclitaxel is included in WHO Model List of Essential Medicines for treatment of various cancers. |
| ICMR Guideline | ICMR guidelines recommend paclitaxel for breast, ovarian, and lung cancers as per standard protocols. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paclitaxel stabilizes microtubules by promoting their assembly and preventing their disassembly. This disruption of microtubule dynamics leads to cell cycle arrest in the G2/M phase and subsequent cell death. Cancer cells are particularly sensitive to this effect, which inhibits their proliferation.
Mechanism Steps
💡 How to Take intaxel 30mg injection
Strength: Injection: 30 mg per vial
Dosage Information
| Adult Dosage | The dose of this medicine is individualized based on the type of cancer, stage, prior treatments, and patient factors. Common regimens include 175 mg/m² administered intravenously over 3 hours every 3 weeks, or 135 mg/m² over 24 hours every 3 weeks. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects such as neuropathy and myelosuppression. Dose adjustments may be necessary based on organ function. |
| Renal Impairment | No specific dose adjustment is recommended for renal impairment, but monitor closely. |
| Hepatic Impairment | Dose reduction is recommended for patients with hepatic impairment. For mild impairment, consider 135 mg/m²; for moderate to severe, avoid or reduce further. |
| Maximum Daily Dose | Not applicable as dosing is per cycle. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of intaxel 30mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Gemfibrozil | Major | |
| Warfarin | Moderate | |
| Doxorubicin | Moderate |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP2C8 inhibitors (e.g., gemfibrozil)
- Live vaccines
⚡ Moderate Interactions
- Warfarin
- Doxorubicin
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and should be avoided during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to paclitaxel or other taxanes","Severe hepatic impairment","Baseline neutrophil count
⚠️ Warnings & Precautions
["Administer only under supervision of experienced oncologist.","Premedicate with corticosteroids, antihistamines, and H2 antagonists to prevent hypersensitivity reactions.","Monitor for bone marrow suppression.","Avoid live vaccines.","Use with caution in patients with cardiac disorders."]
🤱 Lactation Safety
It is not known if paclitaxel is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding should be discontinued during treatment.
💊 Overdose Management
Overdose may cause severe myelosuppression, neuropathy, and mucositis. There is no specific antidote. Treatment is supportive and symptomatic. Patients should be monitored closely.
⏰ Missed Dose
If a dose is missed, contact your healthcare provider immediately. Do not double the dose to catch up.
Additional Safety Advice
This medicine must only be administered by a qualified healthcare professional in a clinical setting equipped to manage potential allergic reactions. Regular blood tests are required to monitor blood cell counts, liver function, and kidney function. Patients should avoid contact with people who have infections and should practice good hygiene. Contraception is advised during treatment and for some time after, for both men and women. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not receive any vaccinations without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may experience more side effects. Dose adjustments may be needed based on organ function.
🤰 Pregnancy Planning (TTC)
This medicine can harm the fetus. Use effective contraception during treatment and for at least 6 months after. Consult your doctor if you plan to become pregnant.
🏥 Post-Surgery Considerations
This medicine may affect wound healing. Inform your surgeon if you are receiving this medicine.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine. It may increase the risk of bleeding and infection.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during treatment. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Treatment may cause fatigue, making it difficult to work. Discuss with your employer about flexible arrangements.
🛑 When to Stop This Medicine
Do not stop treatment without consulting your oncologist. Stopping prematurely may reduce effectiveness.
📅 Long-Term Use Effects
Long-term effects may include persistent peripheral neuropathy, cardiac issues, and secondary cancers. Regular follow-up and monitoring are essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Docetaxel or other taxanes may be used if paclitaxel is not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment. Inactivated vaccines may be given, but consult your doctor.
📦 Storage Guide
✅ DO
Store refrigerated at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if particles are present
✈️ Traveling with This Medicine
This medicine is administered in a healthcare setting, so travel is not applicable. However, if you are traveling for treatment, carry your prescription and medical records. Store the medicine as directed by your healthcare provider. Ensure you have contact information for your oncologist.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects on cancer cells begin after administration, but visible tumor shrinkage may take weeks to months.
A: This medicine may cause fatigue or dizziness. Avoid driving until you know how it affects you.
A: Avoid alcohol, live vaccines, and contact with people who have infections.
🤔 Common Patient Concerns
🔄 Substitutes for intaxel 30mg injection
View AllAlternative brands with exact same active ingredient:
-
oncotaxel 30mg injectionSun Pharmaceutical Industries Ltd ₹31.70 97.2% CHEAPER
-
Taxeleon 30mg InjectionNeon Laboratories Ltd ₹385.30 66.5% CHEAPER
-
dutaxel 30mg injectionSamarth Life Sciences Pvt Ltd ₹396.50 65.5% CHEAPER
-
Relipac 30mg InjectionReliance Life Sciences ₹445.23 61.3% CHEAPER
-
kansure 30mg injectionKhandelwal Laboratories Pvt Ltd ₹481.80 58.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken orally.
Fact: This medicine is given intravenously only. - Myth: This medicine is safe to take at home.
Fact: It must be administered in a clinic or hospital setting.
🔄 Alternative Options
Generic Alternatives
- Paclitaxel injection
Brand Alternatives
- Dutaxel 30mg injection