Frimol-SR Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Severe abdominal pain or tenderness
- Dark urine or pale stools
- Blood in vomit or black, tarry stools
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe skin rash with blisters or peeling
- Unusual bleeding or bruising
- Decreased urine output
- Persistent high fever not responding to treatment
If experiencing severe symptoms, call emergency services immediately.
What is instaflex p tablet sr used for?
This medicine is a sustained-release tablet containing 1000 mg of Paracetamol. It is used to relieve mild to moderate pain and reduce fever. It works by blocking pain signals and lowering fever in the brain. The sustained-release form provides longer-lasting relief. It should be swallowed whole and not crushed. Do not exceed 4 tablets in 24 hours.
- Generic Name: Paracetamol (300mg) + Paracetamol (700mg)
- Manufacturer: Innovcare Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 instaflex p tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल का एक सस्टेन्ड-रिलीज़ फॉर्मूलेशन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मासिक धर्म के दर्द, मांसपेशियों में दर्द, पीठ दर्द और सर्दी-जुकाम से जुड़े दर्द में राहत देती है। यह शरीर के तापमान को कम करने में भी मदद करती है। यह दवा दर्द संकेतों को कम करके और मस्तिष्क में बुखार को नियंत्रित करके काम करती है। सस्टेन्ड-रिलीज़ होने के कारण यह दवा धीरे-धीरे रिलीज़ होती है और लंबे समय तक असर देती है। इसे पूरा निगलना चाहिए, चबाना या तोड़ना नहीं चाहिए।
साइड इफेक्ट्स: आमतौर पर यह दवा सही खुराक में लेने पर अच्छी तरह सहन की जाती है। कुछ लोगों को मतली, पेट में असहजता, या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन त्वचा पर गंभीर प्रतिक्रियाएं, लीवर की क्षति, या खून से जुड़ी समस्याएं हो सकती हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अनुशंसित खुराक से अधिक न लें और बिना सलाह के लंबे समय तक न लें। इस दवा के साथ शराब न पिएं क्योंकि इससे लीवर को नुकसान का खतरा बढ़ जाता है। पैरासिटामोल युक्त अन्य दवाओं के साथ इसका सेवन न करें। गोली को पूरा निगलें, चबाएं नहीं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 instaflex p tablet sr Uses & Benefits
[{"condition":"Mild to moderate pain","description":"Relieves pain such as headache, toothache, menstrual cramps, muscle aches, and back pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces elevated body temperature in conditions such as colds and flu.","evidence":"Well-established"},{"condition":"Osteoarthritis pain","description":"Provides symptomatic relief of pain in osteoarthritis, though it does not reduce inflammation.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used for acute migraine attacks, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Headache, Toothache, Menstrual cramps, Muscle aches, Back pain, Osteoarthritis
📋 Drug Information
| Generic Name(s) | Paracetamol (300mg) + Paracetamol (700mg) |
| Brand Name | instaflex p tablet sr |
| Manufacturer | Innovcare Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paracetamol, the active ingredient of this medicine, produces analgesia and antipyresis primarily through central nervous system effects. It inhibits the synthesis of prostaglandins in the brain by acting on cyclooxygenase (COX) enzymes, particularly COX-2 and a variant called COX-3. Unlike nonsteroidal anti-inflammatory drugs (NSAIDs), Paracetamol has little anti-inflammatory activity and does not inhibit platelet aggregation. It also acts on the descending serotonergic pathways and may interact with cannabinoid receptors, contributing to its pain-relieving effect. The antipyretic effect is due to inhibition of prostaglandin E2 synthesis in the hypothalamus, which lowers the body's temperature set point. The sustained-release formulation of this medicine allows gradual release of Paracetamol over several hours, providing prolonged relief.
Mechanism Steps
💡 How to Take instaflex p tablet sr
Strength: Sustained-release tablet containing Paracetamol 300 mg and Paracetamol 700 mg (total 1000 mg per tablet).
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet (1000 mg Paracetamol) taken orally every 8 to 12 hours as needed for pain or fever. The maximum recommended dose is 3000 mg to 4000 mg of Paracetamol per day from all sources. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. This medicine is for short-term use unless otherwise directed by your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to the side effects of Paracetamol, especially liver and kidney effects. Use with caution and at the lowest effective dose. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance less than 30 mL/min), the dosing interval should be increased. Consult your doctor for specific dosing recommendations. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with hepatic impairment, the dose should be reduced or the dosing interval increased. In severe hepatic impairment, this medicine is contraindicated. Consult your doctor for specific dosing recommendations. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of Paracetamol from all sources should not exceed 4000 mg for adults. For this medicine, the maximum daily dose is 4 tablets (4000 mg) per day. However, lower doses may be recommended based on individual factors. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of instaflex p tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Isoniazid | Moderate | |
| Metoclopramide | Minor | |
| Cholestyramine | Minor | |
| Other Paracetamol products | Major |
🚨 Major Interactions
- Warfarin
- Alcohol
- Other Paracetamol-containing products
⚡ Moderate Interactions
- Carbamazepine, Phenytoin, Rifampicin
- Isoniazid
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Chronic heavy alcohol consumption increases the risk of Paracetamol-induced liver damage. Even moderate alcohol intake may increase this risk. If you consume alcohol regularly, inform your doctor before taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to Paracetamol","Severe liver disease or active liver failure","Severe kidney disease","Chronic alcohol abuse","Malnutrition or low glutathione levels"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose. Taking more than the maximum daily dose can cause serious liver damage.","Avoid alcohol while taking this medicine.","Do not use other Paracetamol-containing products concurrently.","Use with caution in patients with liver or kidney disease.","Swallow the sustained-release tablet whole; do not crush or chew.","Consult a doctor if pain or fever persists for more than 3 days or worsens.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Paracetamol is excreted in breast milk in small amounts. It is generally considered safe for use during breastfeeding when taken at the recommended dose. Monitor the infant for any unusual signs. Consult your doctor before use.
💊 Overdose Management
Overdose of Paracetamol can cause severe liver damage, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and loss of appetite, but may not appear immediately. If you suspect an overdose, seek emergency medical help immediately, even if you feel well. The antidote is N-acetylcysteine, which is most effective when given within 8 to 10 hours of overdose. Do not wait for symptoms to appear. Contact a poison control center or go to the nearest emergency room.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose, and do not take it for longer than advised without consulting your doctor. Avoid drinking alcohol while taking this medicine because it increases the risk of liver damage. Do not take other medicines containing Paracetamol at the same time to avoid exceeding the maximum daily dose. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. If you have liver or kidney disease, or if you are pregnant or breastfeeding, tell your doctor before taking this medicine. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially liver and kidney effects. They may also be taking other medications that could interact. Use with caution and at the lowest effective dose. Regular monitoring of liver and kidney function may be advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Paracetamol is generally considered safe during pregnancy when used at recommended doses for short periods. However, prolonged use should be avoided unless advised by a doctor.
🏥 Post-Surgery Considerations
This medicine can be used for post-surgical pain relief as directed by your doctor. It is important to follow the prescribed dose and not exceed the maximum daily limit. Inform your surgeon if you are taking this medicine before surgery.
🦷 Dental Procedures
This medicine can be taken for dental pain, including after dental procedures. Inform your dentist if you are taking this medicine, especially if you are also taking other painkillers or blood thinners.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. If you experience dizziness, lie down and rest. Consult your doctor before starting any new exercise regimen while on this medicine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. If affected, avoid driving, operating machinery, or performing tasks that require alertness. It is generally safe to continue normal daily activities if you do not experience these side effects. Inform your employer if your work involves operating heavy machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain or fever persists for more than 3 days, if symptoms worsen, or if you experience any serious side effects such as skin rash, yellowing of eyes, or severe abdominal pain. Do not stop abruptly if you have been taking it regularly for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine at high doses can increase the risk of liver and kidney damage. Regular monitoring of liver and kidney function may be necessary if used for extended periods. It is important not to exceed the recommended dose and to avoid alcohol. Consult your doctor if you need to take this medicine for more than 10 days for pain or 3 days for fever.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage chronic pain through exercises and manual techniques.
Evidence: Well-establishedApplying heat or cold packs can relieve localized pain and inflammation.
Evidence: ModerateDeep breathing, meditation, and yoga can help reduce pain perception.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever. However, consult your doctor if you have any concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking your doses at the same intervals as prescribed, but consult your doctor for specific advice. Keep it in your carry-on luggage to avoid loss. Check local customs regulations regarding controlled substances, though Paracetamol is generally not restricted.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 1 to 2 hours after taking it. The sustained-release form provides longer-lasting relief, usually up to 8-12 hours.
A: It can be taken on an empty stomach, but taking it with food may reduce the risk of stomach upset.
A: It can interact with certain medicines like Warfarin and other Paracetamol-containing products. Always inform your doctor about all medicines you are taking.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is generally not recommended for long-term use without medical supervision. Prolonged use may increase the risk of liver and kidney problems. Consult your doctor if you need it for more than a few days.
🤔 Common Patient Concerns
🔄 Substitutes for instaflex p tablet sr
View AllAlternative brands with exact same active ingredient:
-
xykaa extend 1000 tabletTroikaa Pharmaceuticals Ltd ₹41.81 33.4% CHEAPER
-
femol 300mg/700mg tablet srAmbreyo Lifesciences ₹42.19 32.8% CHEAPER
-
maxmol 300mg/700mg tablet srMaxamus Pharma Pvt Ltd ₹42.19 32.8% CHEAPER
-
plentimol 300mg/700mg tablet srPlenteous Pharmaceuticals Ltd ₹43.13 31.3% CHEAPER
-
retol xt 300mg/700mg tablet srOlcare Laboratories ₹45.94 26.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Paracetamol is completely safe and can be taken in any amount.
Fact: Paracetamol is safe only when taken at recommended doses. Overdose can cause severe liver damage. - Myth: Sustained-release tablets can be crushed for easier swallowing.
Fact: Crushing or chewing sustained-release tablets can cause all the medicine to be released at once, increasing the risk of side effects. - Myth: Paracetamol and NSAIDs are the same.
Fact: Paracetamol has little anti-inflammatory effect and does not cause stomach ulcers like NSAIDs.
🔄 Alternative Options
Generic Alternatives
- Paracetamol sustained-release tablet 1000 mg
Brand Alternatives
- Frimol-SR Tablet