Dispar 300mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Dark-colored urine or pale stools
- Severe abdominal pain or tenderness
- Blood in vomit or black, tarry stools
- Difficulty breathing or swelling of the face, lips, or throat
- Unusual bruising or bleeding
- Decreased urine output or inability to urinate
- Severe skin rash with blistering or peeling
If experiencing severe symptoms, call emergency services immediately.
What is hitem 300mg tablet md used for?
This medicine contains paracetamol 300 mg, an analgesic and antipyretic used to relieve mild to moderate pain and reduce fever. It works by reducing prostaglandin production in the brain. The usual adult dose is 300 mg to 1000 mg every 4 to 6 hours as needed, not exceeding 4000 mg per day. Always follow your doctor's advice.
- Generic Name: Paracetamol (300mg)
- Manufacturer: Sigman Wellness
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 hitem 300mg tablet md के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल 300 मिलीग्राम की एक टैबलेट है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार को कम करने के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मासिक धर्म के दर्द, मांसपेशियों के दर्द और पीठ दर्द में राहत देती है। यह बुखार को भी कम करती है। यह दवा मस्तिष्क में प्रोस्टाग्लैंडिन नामक पदार्थ के उत्पादन को कम करके काम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें। अधिक मात्रा में लेने से लीवर को नुकसान हो सकता है।
साइड इफेक्ट्स: आमतौर पर यह दवा सही मात्रा में लेने पर सुरक्षित मानी जाती है। कुछ लोगों को मतली, पेट में असहजता या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन लीवर की क्षति, गंभीर त्वचा प्रतिक्रियाएं और रक्त विकार हो सकते हैं। अगर आपको पीलिया, गहरे रंग का पेशाब, पेट में तेज दर्द या आसानी से चोट लगने जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। अनुशंसित मात्रा से अधिक न लें और बिना सलाह के लंबे समय तक न लें। इस दवा के साथ शराब न पिएं, क्योंकि इससे लीवर को नुकसान का खतरा बढ़ जाता है। अगर आपको लीवर या किडनी की समस्या है, या आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। बुखार के लिए 3 दिन से अधिक और दर्द के लिए 10 दिन से अधिक इस दवा का उपयोग न करें। बच्चों की पहुंच से दूर रखें।
💊 hitem 300mg tablet md Uses & Benefits
[{"condition":"Mild to moderate pain","description":"Relieves pain such as headache, toothache, menstrual cramps, muscle aches, and back pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever by acting on the hypothalamus to lower body temperature.","evidence":"Well-established"},{"condition":"Osteoarthritis pain","description":"Provides symptomatic relief of mild to moderate pain associated with osteoarthritis.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used as part of multimodal analgesia for mild to moderate post-operative pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, though evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but NSAIDs are generally preferred.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Osteoarthritis, Headache, Menstrual cramps, Toothache, Muscle aches
📋 Drug Information
| Generic Name(s) | Paracetamol (300mg) |
| Brand Name | hitem 300mg tablet md |
| Manufacturer | Sigman Wellness |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Analgesic & Antipyretic-PCM |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | Typically 24 to 36 months from the date of manufacture. Refer to the packaging for the exact expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works primarily in the central nervous system. It reduces the synthesis of prostaglandins in the brain by inhibiting the cyclooxygenase (COX) enzymes, particularly COX-2, but its action is different from NSAIDs because it does not significantly inhibit COX enzymes in peripheral tissues. This central action helps to relieve pain and reduce fever. Additionally, it may act on the hypothalamic heat-regulating center to produce antipyresis. The exact mechanism is not fully understood, but it is believed to involve multiple pathways including inhibition of prostaglandin E2 synthesis and activation of descending serotonergic pathways.
Mechanism Steps
💡 How to Take hitem 300mg tablet md
Strength: Immediate-release tablet, 300 mg
Dosage Information
| Adult Dosage | For adults and children over 12 years, the usual dose is 300 mg to 1000 mg every 4 to 6 hours as needed for pain or fever. The maximum recommended daily dose is 4000 mg (4 grams) from all sources. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific 300 mg tablet. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more susceptible to the side effects of this medicine. Use with caution and adjust the dose as advised by a clinician, especially in those with liver or kidney impairment. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance less than 30 mL/min), the dosing interval should be increased. Consult a doctor for dose adjustment. |
| Hepatic Impairment | In patients with hepatic impairment, the dose should be reduced or the dosing interval increased. Avoid use in severe liver disease. Consult a doctor for guidance. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 4000 mg (4 grams) from all sources. For this 300 mg tablet, that would be a maximum of 13 tablets per day, but the actual dose should be determined by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of hitem 300mg tablet md
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Isoniazid | Moderate | |
| Metoclopramide | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
⚡ Moderate Interactions
- Carbamazepine, phenytoin, rifampicin
- Isoniazid
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of liver damage, especially with regular or high-dose use of paracetamol. Even moderate drinking may enhance the toxic effects on the liver.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe liver disease or active liver failure","Known hypersensitivity to paracetamol or any component of the formulation","Severe kidney impairment (use with caution)"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose. Taking more than the maximum daily dose can cause serious liver damage.","Avoid concomitant use with other paracetamol-containing products.","Use with caution in patients with chronic alcohol consumption.","Consult a doctor before use in patients with liver or kidney disease.","Discontinue use and seek medical advice if symptoms persist or worsen.","Keep out of reach of children."]
🤱 Lactation Safety
Paracetamol is excreted in breast milk in small amounts. It is generally considered safe for use during breastfeeding when taken at recommended doses. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and sweating within the first 24 hours, followed by liver failure. If you suspect an overdose, seek emergency medical attention immediately, even if you feel well. The antidote is N-acetylcysteine, which is most effective when given within 8-10 hours of ingestion. Do not wait for symptoms to appear.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised without consulting a healthcare professional. Avoid drinking alcohol while taking this medicine, as it increases the risk of liver damage. If you have liver or kidney problems, or if you are pregnant or breastfeeding, inform your doctor before taking this medicine. Do not use this medicine to treat a fever for more than 3 days or pain for more than 10 days unless directed by a doctor. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Never double the dose to make up for a missed one.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially if they have liver or kidney impairment. Lower doses or longer dosing intervals may be needed. Consult a doctor for guidance.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Paracetamol is generally considered safe during pregnancy when used as directed, but prolonged use should be avoided.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief as part of a multimodal approach. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
This medicine can be taken for dental pain, including after dental procedures. Inform your dentist that you are taking it. It does not typically interfere with dental anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can generally exercise as normal. However, if you are taking it for pain, avoid activities that worsen your condition. Listen to your body and rest if you feel dizzy or unwell.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it usually does not interfere with daily activities.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve after 3 days for fever or 10 days for pain, or if they worsen. Do not stop suddenly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine at high doses can lead to liver damage and kidney problems. It is not recommended for chronic use without medical supervision. Regular monitoring of liver and kidney function may be advised if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage chronic pain and improve mobility.
Evidence: Well-establishedMay provide local pain relief for muscle aches and strains.
Evidence: Well-establishedCan help reduce tension headaches and stress-related pain.
Evidence: Some evidence💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever. However, consult your doctor if you have concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust your dosing schedule accordingly, but do not exceed the maximum daily dose. Check local customs regulations regarding carrying medicines. Always keep it in your carry-on luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it by mouth.
A: It can be taken on an empty stomach, but taking it with food may reduce the chance of stomach upset.
A: It should not be taken daily for long periods without medical advice. Prolonged use may increase the risk of liver damage.
A: Seek emergency medical help immediately, even if you feel fine. Overdose can cause delayed liver damage.
🤔 Common Patient Concerns
🔄 Substitutes for hitem 300mg tablet md
View AllAlternative brands with exact same active ingredient:
-
zadumol 300 tabletPanm Labs India ₹12.66 35% COSTLIER
-
dispar 300mg tabletRekvina Laboratories Ltd ₹13.50 43.9% COSTLIER
-
myopal-d 300mg tabletAnhox Healthcare Pvt Ltd ₹14.06 49.9% COSTLIER
-
dispar kid 300mg tabletRekvina Laboratories Ltd ₹15.00 59.9% COSTLIER
-
tyfy 300mg tablet dtVanguard Therapeutics Pvt Ltd ₹27.30 191% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Paracetamol is completely safe and you can take as much as you want.
Fact: Exceeding the recommended dose can cause severe liver damage. Always follow the prescribed dose. - Myth: Paracetamol is an anti-inflammatory medicine like ibuprofen.
Fact: Paracetamol has little to no anti-inflammatory effect. It primarily relieves pain and fever. - Myth: You can drink alcohol while taking paracetamol without any risk.
Fact: Alcohol increases the risk of liver damage when taken with paracetamol. It is best to avoid alcohol.
🔄 Alternative Options
Generic Alternatives
- Paracetamol 300 mg tablet (various manufacturers)