Inflagesic Gel: Comprehensive Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Severe skin irritation or blistering
- Signs of systemic NSAID effects (stomach pain, black stools)
- Decreased urine output
- Yellowing of skin or eyes
- Chest pain or shortness of breath
If experiencing severe symptoms, call emergency services immediately.
What is inflagesic gel used for?
This medicine is a topical gel combining aceclofenac and capsaicin-based rubefacients. It is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and soft tissue injuries. Apply a thin layer to the affected area 2-3 times daily, or as directed by your doctor.
- Generic Name: Aceclofenac (1.5%) + Capsaicin Based Rubefacients (3%)
- Manufacturer: Themis Medicare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 inflagesic gel के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल जेल है जिसमें एसिफेनाक और कैप्साइसिन जैसे तत्व होते हैं। यह जोड़ों के दर्द, मांसपेशियों के दर्द, और सूजन को कम करने के लिए उपयोग की जाती है। इसे प्रभावित जगह पर दिन में 2-3 बार लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर जलन, लालिमा, खुजली हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई हो सकती है। ऐसा होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को केवल त्वचा पर लगाएं। आंखों, मुंह, और घाव वाली जगह पर न लगाएं। लगाने के बाद हाथ धो लें। 7 दिन से ज्यादा इस्तेमाल न करें। गर्भवती महिलाएं डॉक्टर से सलाह लें।
💊 inflagesic gel Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Provides symptomatic relief of pain and stiffness in affected joints.","evidence":"Moderate"},{"condition":"Soft tissue injuries","description":"Reduces pain and inflammation in sprains, strains, and sports injuries.","evidence":"Moderate"},{"condition":"Muscle pain","description":"Eases localized muscle aches and soreness.","evidence":"Limited"}]
Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes used off-label for localized neuropathic pain due to capsaicin content.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Soft tissue injuries, Muscle pain
📋 Drug Information
| Generic Name(s) | Aceclofenac (1.5%) + Capsaicin Based Rubefacients (3%) |
| Brand Name | inflagesic gel |
| Manufacturer | Themis Medicare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, reducing prostaglandin synthesis and thereby decreasing inflammation and pain. Capsaicin, a natural alkaloid, binds to transient receptor potential vanilloid 1 (TRPV1) receptors on sensory neurons, leading to initial excitation followed by desensitization and depletion of substance P, a key neurotransmitter in pain transmission. This results in a warming sensation and subsequent pain relief.
Mechanism Steps
💡 How to Take inflagesic gel
Strength: Gel containing Aceclofenac 1.5% w/w and Capsaicin-based rubefacients 3% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area 2 to 3 times daily, or as directed by your doctor. Gently massage until absorbed. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended frequency. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required, but use with caution due to increased risk of systemic effects. Consult a doctor. |
| Renal Impairment | No dose adjustment is typically needed for topical use, but caution is advised in severe renal impairment. Consult a doctor. |
| Hepatic Impairment | No dose adjustment is typically needed for topical use, but caution is advised in severe hepatic impairment. Consult a doctor. |
| Maximum Daily Dose | Not established from the available information. Do not exceed the frequency recommended by your doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of inflagesic gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Oral NSAIDs | Major | |
| Antihypertensives | Moderate | |
| Diuretics | Moderate |
🚨 Major Interactions
- Oral NSAIDs
- Anticoagulants (e.g., warfarin)
⚡ Moderate Interactions
- Antihypertensives
- Diuretics
🍷 Alcohol Interaction
No known interaction with alcohol when used topically, but excessive alcohol may increase risk of stomach bleeding if systemic absorption occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aceclofenac, capsaicin, or any component","Application to broken skin, eyes, or mucous membranes","History of asthma, urticaria, or allergic reactions to NSAIDs","Severe renal or hepatic impairment","Third trimester of pregnancy"]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes and mucous membranes.","Do not apply to wounds or damaged skin.","Do not use with occlusive dressings.","Discontinue if severe irritation occurs.","Consult doctor if symptoms persist beyond 7 days.","Keep out of reach of children.","Use with caution in elderly patients."]
🤱 Lactation Safety
Not established from the available information. Avoid application to the breast area and consult a doctor.
💊 Overdose Management
Overdose is unlikely with topical use. If accidental ingestion occurs, seek immediate medical attention. Symptoms may include stomach pain, nausea, or vomiting. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply double quantity to make up for a missed dose.
Additional Safety Advice
Apply this medicine only to intact skin and avoid contact with eyes, mucous membranes, and open wounds. Wash hands thoroughly after application unless the hands are the treated area. Do not cover the treated area with airtight dressings or apply heat, as this may increase absorption and risk of side effects. Avoid sun exposure to treated areas. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Inform your doctor if you have a history of asthma, kidney disease, or stomach ulcers. Do not use other topical products on the same area without consulting a doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to skin irritation and systemic effects. Use with caution and monitor.
🤰 Pregnancy Planning (TTC)
Consult your doctor before use if you are planning pregnancy.
🏥 Post-Surgery Considerations
Consult your surgeon before applying to surgical sites.
🦷 Dental Procedures
No specific considerations for dental procedures, but inform your dentist if you are using this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise on treated areas immediately after application. Consult a physiotherapist for appropriate exercises.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and does not affect driving or operating machinery. However, avoid touching treated areas to others.
🛑 When to Stop This Medicine
Stop use if you experience severe skin irritation or allergic reactions. Consult a doctor before stopping if you have been using it for a chronic condition.
📅 Long-Term Use Effects
Long-term use over large areas may increase the risk of systemic NSAID effects such as gastrointestinal or renal issues. Monitor for skin reactions and consult a doctor if symptoms persist beyond 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay provide additional relief.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. No time zone adjustments are needed for topical use. Declare it at customs if traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief may begin within 30 minutes to 1 hour after application, with capsaicin's warming effect felt immediately.
A: No, avoid applying to the face, eyes, and mucous membranes.
A: Consult your doctor before use, especially in the third trimester.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken orally.
Fact: This medicine is for topical use only and must not be ingested. - Myth: More gel means faster relief.
Fact: Applying more than the recommended amount does not improve efficacy and may increase side effects.