infen p tablet - Dexketoprofen (25mg) + Paracetamol (325mg) medicine

Deket-P 25mg/325mg Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Emcure Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. NSAIDs are generally avoided in the third trimester due to risk of premature closure of the ductus arteriosus. Paracetamol is considered relatively safe in pregnancy when used at recommended doses. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term acute pain.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is infen p tablet used for?

This medicine is a combination of dexketoprofen and paracetamol used for short-term relief of moderate to severe acute pain. It works by reducing inflammation and pain signals. Take it with food and do not exceed 3 tablets in 24 hours.

  • Generic Name: Dexketoprofen (25mg) + Paracetamol (325mg)
  • Manufacturer: Emcure Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 infen p tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डेक्सकीटोप्रोफेन और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर तीव्र दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द और मासिक धर्म के दर्द में राहत देती है। इसे भोजन के साथ लें और 24 घंटे में 3 गोलियों से अधिक न लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट या आंतों में रक्तस्राव, एलर्जी प्रतिक्रिया, लीवर और किडनी की समस्या शामिल हो सकती है। यदि आपको काला मल, उल्टी में खून, या गंभीर पेट दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें और निर्देशित अवधि से अधिक समय तक न लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न लें क्योंकि इससे लीवर और पेट की समस्या का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको किडनी, लीवर, या हृदय रोग है, तो डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 infen p tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves moderate to severe pain from muscle strains, sprains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgery.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves painful menstrual cramps.","evidence":"Well-established"},{"condition":"Acute gout","description":"May be used for short-term relief of acute gout attacks.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine pain, but not first-line.","evidence":"Limited"},{"condition":"Renal colic","description":"May be used off-label for pain from kidney stones, but other treatments are preferred.","evidence":"Limited"}]

Primary treatment for: Acute pain

Also treats: Musculoskeletal pain, Dental pain, Post-operative pain, Dysmenorrhea

📋 Drug Information

Generic Name(s)Dexketoprofen (25mg) + Paracetamol (325mg)
Brand Nameinfen p tablet
ManufacturerEmcure Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach irritation.
2
Do not exceed 3 tablets in 24 hours to avoid liver damage from paracetamol.
3
Avoid alcohol completely while taking this medicine.
4
Do not use this medicine for more than 3-5 days without consulting your doctor.
5
If you have a history of stomach ulcers, kidney disease, or heart disease, inform your doctor before taking this medicine.
6
Report any unusual bleeding, bruising, or yellowing of eyes to your doctor immediately.
7
Do not take other pain relievers containing paracetamol or NSAIDs without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acute musculoskeletal pain
This medicine is commonly prescribed for this.
Likely Use
✅
Dental pain
This medicine is effective for dental pain.
Likely Use
❌
Fever
This medicine is not a primary fever reducer, though paracetamol has antipyretic effects.
Not Primary
❌
Chronic pain
This medicine is for short-term use only; chronic pain requires other treatments.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDexketoprofen is rapidly absorbed after oral administration, with peak plasma concentrations reached within 30 minutes. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract, with peak levels occurring within 30 to 60 minutes. Food may delay absorption slightly but does not significantly affect the extent of absorption.
DistributionDexketoprofen is highly bound to plasma proteins (99%) and has a small volume of distribution. Paracetamol is distributed widely throughout most body tissues, with a volume of distribution of about 0.95 L/kg. Both drugs cross the placenta and are excreted in breast milk to some extent.
Protein BindingDexketoprofen is approximately 99% bound to plasma proteins, primarily albumin. Paracetamol is only about 10-25% bound to plasma proteins.
MetabolismDexketoprofen is metabolized in the liver primarily by glucuronidation and to a lesser extent by CYP2C9-mediated oxidation. Paracetamol is metabolized in the liver, mainly by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of dexketoprofen is approximately 1.5 to 2.5 hours. Paracetamol has a half-life of about 2 to 3 hours in healthy adults.
ExcretionDexketoprofen is excreted primarily in the urine as metabolites. Paracetamol is excreted in the urine as glucuronide and sulfate conjugates, with less than 5% excreted unchanged.
BioavailabilityThe oral bioavailability of dexketoprofen is approximately 70-80%. Paracetamol has a high oral bioavailability of about 80-100%.
Onset of ActionPain relief typically begins within 30 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 30 to 60 minutes for both components.
Duration of ActionPain relief lasts approximately 4 to 6 hours, so dosing is usually every 6 to 8 hours as needed.

How It Works

This medicine combines two active ingredients with different mechanisms. Dexketoprofen is a non-steroidal anti-inflammatory drug that works by inhibiting the cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2, which are responsible for converting arachidonic acid into prostaglandins. Prostaglandins are chemicals that mediate pain, inflammation, and fever. By blocking their production, dexketoprofen reduces pain and swelling. Paracetamol, on the other hand, acts primarily in the central nervous system. It inhibits prostaglandin synthesis in the brain and may also activate descending inhibitory pathways that reduce pain perception. Additionally, paracetamol has antipyretic effects by acting on the hypothalamus to lower fever. The combination provides enhanced pain relief through complementary mechanisms.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Dexketoprofen binds to and inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This inhibition decreases the production of prostaglandins, which are key mediators of pain, inflammation, and fever.
3
Central analgesic action of paracetamol: Paracetamol acts on the central nervous system, possibly by inhibiting prostaglandin synthesis in the brain and spinal cord, and modulating pain perception.
4
Antipyretic effect: Paracetamol acts on the hypothalamus to reduce fever by promoting heat loss.
5
Combined pain relief: The complementary mechanisms of dexketoprofen and paracetamol result in enhanced analgesic efficacy.

💡 How to Take infen p tablet

Strength: Each tablet contains dexketoprofen 25 mg and paracetamol 325 mg.

1Take the tablet orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Do not exceed the recommended dose.
5Follow your doctor's instructions for the duration of treatment.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 6 to 8 hours as needed for pain, not exceeding 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with food to reduce stomach upset. Use for the shortest duration necessary.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and kidney side effects. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose adjustment may be necessary. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose is 3 tablets in 24 hours (75 mg dexketoprofen and 975 mg paracetamol). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage and gastrointestinal bleeding.
Caffeine
Limit
May increase stomach irritation and jitteriness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of infen p tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Stomach pain or indigestion (Common (5-10%))
Take with food or milk. Avoid spicy foods. If severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness. Consult doctor if excessive.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.
Allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Liver damage (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Seek immediate medical attention for chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek emergency care for rash with blisters, peeling skin, or sores in mouth.
Blood disorders (agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor.
Aseptic meningitis
Seek immediate care for severe headache, stiff neck, fever, and sensitivity to light.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
ACE inhibitors Moderate
Diuretics Moderate
Lithium Moderate
SSRIs Moderate
Antacids Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate
  • ACE inhibitors and ARBs

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Lithium
  • SSRIs
  • Anticoagulants (e.g., apixaban, rivaroxaban)

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding from dexketoprofen and can potentiate liver damage from paracetamol. It may also increase drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure, liver disease, or kidney disease","Allergy to dexketoprofen, paracetamol, or other NSAIDs","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Third trimester of pregnancy","Children under 18 years (unless specifically prescribed)","Concurrent use with other NSAIDs","Active bleeding disorders"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Do not exceed the recommended dose due to risk of liver damage from paracetamol.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma.","Do not drive or operate machinery if you feel dizzy or drowsy.","Consult your doctor if pain persists beyond 3-5 days or worsens.","Do not use for chronic pain without medical supervision."]

🤱 Lactation Safety

Dexketoprofen and paracetamol are excreted in breast milk in small amounts. Short-term use of paracetamol is generally considered safe during breastfeeding. However, NSAIDs like dexketoprofen should be used with caution, especially for prolonged periods. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding due to dexketoprofen. Symptoms of overdose may include nausea, vomiting, abdominal pain, confusion, and drowsiness. If you suspect an overdose, seek emergency medical attention immediately. Treatment may include activated charcoal, acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Take it with food or a glass of milk to reduce stomach irritation. Avoid alcohol while taking this medicine, as it can increase the risk of liver damage and gastrointestinal bleeding. Do not take other medicines containing paracetamol or other NSAIDs without consulting your doctor, as this can lead to overdose or increased side effects. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, inform your doctor before taking this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events from NSAIDs. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Consult a doctor before use.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like dexketoprofen may interfere with ovulation and are generally avoided during pregnancy, especially in the third trimester. Paracetamol is considered relatively safe but should be used at the lowest effective dose for the shortest time.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain relief, but it should be prescribed by your surgeon. Inform your surgeon about all medicines you are taking. NSAIDs can increase bleeding risk, so use with caution after surgery.

🦷 Dental Procedures

This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure. It may increase bleeding risk during dental surgery. Your dentist may recommend stopping it before certain procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in regular low-impact exercise like swimming or walking.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables in your diet.
🧘
Get adequate sleep to promote healing and pain relief.
🌞
Stay well hydrated throughout the day.

🏋️ Exercise Considerations

While taking this medicine, you may feel dizzy or drowsy. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you experience pain during exercise, stop and rest. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated by drinking plenty of water.
Avoid alcohol and excessive caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue desk work, but take breaks and stay hydrated. Inform your employer if you need accommodations.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain persists beyond 3-5 days, if it worsens, or if you experience any serious side effects such as stomach pain, black stools, or allergic reactions. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of NSAIDs like dexketoprofen can increase the risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Paracetamol overuse can cause liver damage. Regular monitoring of liver and kidney function may be required if used for extended periods. Always consult your doctor before using this medicine for more than a few days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain management.

Evidence: Well-established
Hot and cold therapy

Applying heat or cold packs can help relieve localized pain and inflammation.

Evidence: Well-established
Acupuncture

May provide pain relief for some individuals.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times accordingly, but do not exceed the maximum daily dose. Check customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with severe menstrual cramps
Used this medicine for 2 days during her period. Experienced rapid relief from pain but felt slightly dizzy. She was advised to rest and avoid driving until the dizziness subsided.
💡 Lesson: This medicine provides effective relief for menstrual pain, but dizziness can occur; avoid driving if affected.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe to take with other pain medicines?

A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as this can increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for infen p tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: This medicine is intended for short-term use only. Long-term use increases the risk of side effects.
  • Myth: It is safe to take extra doses if pain is severe.
    Fact: Taking more than the recommended dose can cause serious liver damage and gastrointestinal bleeding.
  • Myth: This medicine is safe to take on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.

🔄 Alternative Options

Generic Alternatives

  • Dexketoprofen 25 mg + Paracetamol 325 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Dexketoprofen + Paracetamol","composition":"Dexketoprofen 25 mg + Paracetamol 325 mg","onset":"30 minutes","duration":"4-6 hours","notes":"Combination provides rapid and enhanced pain relief."},{"medicine":"Ibuprofen + Paracetamol","composition":"Ibuprofen 400 mg + Paracetamol 325 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Similar efficacy but different NSAID component."}]

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