Indocap SR Capsule (Indomethacin 75 mg): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is indocap sr capsule used for?
Indocap SR capsule contains indomethacin 75 mg, a sustained-release NSAID used to treat inflammatory conditions like rheumatoid arthritis, osteoarthritis, and gout. It reduces pain and swelling by blocking prostaglandins. Take it with food, swallow whole, and avoid alcohol. It is not for everyone; consult your doctor about risks and benefits.
- Generic Name: Indomethacin (75mg)
- Manufacturer: Jagsonpal Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 indocap sr capsule के बारे में (Hindi Summary)
उपयोग: यह दवा इंडोमेथासिन 75 मिलीग्राम का सस्टेन्ड-रिलीज़ कैप्सूल है, जिसका उपयोग रूमेटॉयड आर्थराइटिस, ऑस्टियोआर्थराइटिस, एंकिलोज़िंग स्पॉन्डिलाइटिस और गाउट के दौरे जैसी सूजन वाली स्थितियों के इलाज के लिए किया जाता है। यह दर्द, सूजन और अकड़न को कम करने में मदद करता है। यह प्रोस्टाग्लैंडिन नामक रसायनों को रोककर काम करता है जो शरीर में सूजन पैदा करते हैं। इसे भोजन के साथ लें और पूरा निगलें, चबाएं नहीं।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में जलन, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, दिल का दौरा, स्ट्रोक, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हैं। यदि आपको काला मल, खून की उल्टी, सीने में दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। कैप्सूल को पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन या दूध के साथ लें ताकि पेट में जलन कम हो। शराब और अन्य दर्द निवारक दवाओं (जैसे इबुप्रोफेन) से बचें। यदि आपको पेट के अल्सर, हृदय रोग, गुर्दे या यकृत की समस्या है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान बिना सलाह के न लें।
💊 indocap sr capsule Uses & Benefits
[{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness, improving mobility and function.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Relieves pain and inflammation in weight-bearing joints such as knees and hips.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with this inflammatory spine condition.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"Provides rapid relief from the severe pain and swelling of gout attacks.","evidence":"Well-established"},{"condition":"Acute painful shoulder (bursitis/tendinitis)","description":"Reduces inflammation and pain in acute shoulder conditions.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Patent ductus arteriosus (in neonates)","description":"Used off-label in neonates to close a patent ductus arteriosus, but this is a specialized use not for this formulation.","evidence":"Well-established for specific neonatal use"}]
Primary treatment for: Inflammatory joint diseases (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gouty arthritis)
Also treats: Acute painful shoulder (bursitis, tendinitis), Migraine prophylaxis (off-label)
📋 Drug Information
| Generic Name(s) | Indomethacin (75mg) |
| Brand Name | indocap sr capsule |
| Manufacturer | Jagsonpal Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by reversibly inhibiting the enzyme cyclooxygenase (COX), which is responsible for converting arachidonic acid into prostaglandins and thromboxane. By blocking COX, it reduces the production of prostaglandins, which are key mediators of inflammation, pain, and fever. Indomethacin is a non-selective COX inhibitor, meaning it inhibits both COX-1 and COX-2 enzymes. Inhibition of COX-2 provides the anti-inflammatory, analgesic, and antipyretic effects, while inhibition of COX-1 is associated with gastrointestinal and platelet side effects. The sustained-release formulation allows for gradual absorption, providing prolonged therapeutic levels.
Mechanism Steps
💡 How to Take indocap sr capsule
Strength: Sustained-release capsule containing 75 mg of indomethacin.
Dosage Information
| Adult Dosage | The usual adult dose of this sustained-release capsule is 75 mg once or twice daily, depending on the condition being treated. For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, the recommended dose is 75 mg once daily or 75 mg twice daily. For acute gouty arthritis, the dose is 75 mg twice daily until symptoms subside. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) are at increased risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Dose adjustment may be necessary based on kidney function. Consult a doctor for individualized dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Avoid in severe renal impairment (creatinine clearance <30 mL/min). Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 150 mg (two 75 mg capsules). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of indocap sr capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Lithium
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Corticosteroids
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver problems. It may also increase drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to indomethacin or other NSAIDs","Active gastrointestinal bleeding or ulcer","Severe heart failure","Severe kidney disease","Severe liver disease","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Coronary artery bypass graft (CABG) surgery (perioperative period)","Third trimester of pregnancy","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Do not crush, chew, or open the capsule; swallow whole.","Avoid alcohol and other NSAIDs.","Use with caution in elderly patients due to increased risk of side effects.","May cause dizziness; avoid driving until you know how it affects you.","Inform your doctor if you have a history of heart disease, high blood pressure, or kidney problems.","Do not use for more than 10 days for pain unless directed by a doctor.","Report any signs of bleeding, bruising, or infection immediately."]
🤱 Lactation Safety
Indomethacin is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor before use. Monitor the infant for any unusual symptoms.
💊 Overdose Management
Overdose symptoms may include severe nausea, vomiting, stomach pain, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be used if overdose is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the capsule whole with a full glass of water; do not crush, chew, or open it. Take it with food or milk to reduce stomach upset. Do not take more than the prescribed dose or use it for longer than recommended. Avoid alcohol and other NSAIDs (like ibuprofen or naproxen) while on this medicine. Inform your doctor if you have a history of stomach ulcers, heart disease, kidney or liver problems, or high blood pressure. Do not use this medicine if you are pregnant, especially after 30 weeks, or breastfeeding without medical advice. Keep all follow-up appointments and lab tests as scheduled. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and blood pressure regularly. Avoid concomitant use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, as it may cause premature closure of the ductus arteriosus in the fetus. If you are planning pregnancy, consult your doctor to discuss alternative treatments. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
This medicine may increase the risk of bleeding and impair wound healing after surgery. It is contraindicated for perioperative pain in coronary artery bypass graft (CABG) surgery. Consult your surgeon before using this medicine after any surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may recommend stopping it temporarily or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require balance until you know how it affects you. Low-impact exercises like walking or swimming are generally safe and beneficial for joint health.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if your job involves operating heavy machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, especially if you are using it for a chronic condition. Abrupt discontinuation may cause a flare-up of symptoms. Your doctor will advise you on when and how to stop based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, and cardiovascular events. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. It should be used at the lowest effective dose for the shortest duration necessary. Discuss with your doctor if you need to use it for more than a few weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce pain and stiffness in joints.
Evidence: LimitedReduces stress on weight-bearing joints and improves osteoarthritis symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for a vaccination, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Always carry enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 1 to 2 hours, but full anti-inflammatory effects may take a few days to a week.
A: No, it should be taken with food or milk to reduce stomach upset.
A: Avoid alcohol, other NSAIDs, and activities requiring alertness until you know how it affects you.
A: Long-term use increases the risk of stomach bleeding, kidney problems, and heart issues. Use the lowest effective dose for the shortest duration and under medical supervision.
🤔 Common Patient Concerns
🔄 Substitutes for indocap sr capsule
View AllAlternative brands with exact same active ingredient:
-
indodrin 75mg capsule srCapsutab Drugs Pvt Ltd ₹11.25 93.3% CHEAPER
-
ancap 75mg capsule srNoel Pharma India Pvt Ltd ₹32.60 80.6% CHEAPER
-
microcid 75mg capsuleMicro Labs Ltd ₹36.00 78.6% CHEAPER
-
indoflam 75mg capsule trZydus Cadila ₹36.86 78.1% CHEAPER
-
artid 75mg capsule srDigmedi Pvt Ltd ₹39.38 76.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Indocap SR is a simple painkiller for any type of pain.
Fact: It is a potent prescription NSAID for inflammatory conditions, not for ordinary headaches or muscle aches. - Myth: You can crush or chew the capsule for faster relief.
Fact: Crushing or chewing destroys the sustained-release property and can cause serious side effects. Swallow it whole. - Myth: It is safe to take with other painkillers like ibuprofen.
Fact: Combining NSAIDs increases the risk of stomach bleeding and kidney problems. Avoid unless directed by a doctor. - Myth: You can stop taking it as soon as you feel better.
Fact: For chronic conditions, stopping abruptly may cause a flare-up. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Indomethacin sustained-release capsule
Brand Alternatives
- Indocap SR