Abhikof D Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Confusion or hallucinations
If experiencing severe symptoms, call emergency services immediately.
What is imcuf dmr syrup used for?
This medicine is a combination cough syrup containing Bromhexine (a mucolytic) and Dextromethorphan Hydrobromide (a cough suppressant). It is used for short-term relief of dry and productive cough. It works by thinning mucus and suppressing the cough reflex. It should not be used for chronic cough or in children under 12 without medical advice.
- Generic Name: Bromhexine (4mg) + Dextromethorphan Hydrobromide (5mg)
- Manufacturer: Immuna Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 imcuf dmr syrup के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोमहेक्सिन और डेक्सट्रोमेथोर्फन का संयोजन है, जिसका उपयोग सूखी और बलगम वाली खांसी के लक्षणों से राहत के लिए किया जाता है। ब्रोमहेक्सिन बलगम को पतला करता है और डेक्सट्रोमेथोर्फन खांसी की प्रतिक्रिया को दबाता है। यह दवा श्वसन पथ के संक्रमण, एलर्जी या पर्यावरणीय कारकों के कारण होने वाली खांसी में मदद करती है। यह दवा केवल अल्पकालिक उपयोग के लिए है और इसे डॉक्टर की सलाह के बिना लंबे समय तक नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, जी मिचलाना, उल्टी, पेट में परेशानी और सिरदर्द शामिल हैं। कुछ लोगों को मुंह सूखना या गले में जलन महसूस हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको त्वचा पर चकत्ते, खुजली, चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, या भ्रम हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। यदि आपको नींद या चक्कर आते हैं तो वाहन चलाने या मशीनरी चलाने से बचें। इस दवा के साथ शराब का सेवन न करें। यदि आपको लीवर या किडनी की बीमारी, अस्थमा या क्रोनिक ब्रोंकाइटिस है तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 imcuf dmr syrup Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps thin and loosen mucus, making it easier to expel, while suppressing excessive cough reflex.","evidence":"Well-established for short-term symptomatic relief"},{"condition":"Dry, irritating cough","description":"Dextromethorphan suppresses the cough reflex, providing relief from non-productive cough.","evidence":"Well-established for short-term use"},{"condition":"Cough associated with common cold or flu","description":"Provides symptomatic relief of cough and chest congestion.","evidence":"Commonly used, evidence supports symptomatic benefit"}]
Off-label uses: []
Primary treatment for: Cough
Also treats: Common cold, Influenza, Allergic rhinitis, Bronchitis
📋 Drug Information
| Generic Name(s) | Bromhexine (4mg) + Dextromethorphan Hydrobromide (5mg) |
| Brand Name | imcuf dmr syrup |
| Manufacturer | Immuna Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two agents with complementary actions. Bromhexine works by increasing the production of serous fluid in the respiratory tract and breaking down acidic mucopolysaccharide fibers in mucus, thereby reducing mucus viscosity and making it easier to clear. Dextromethorphan acts centrally on the cough center in the medulla oblongata, specifically at sigma-1 receptors, to raise the threshold for cough reflex. It does not cause significant respiratory depression at therapeutic doses.
Mechanism Steps
💡 How to Take imcuf dmr syrup
Strength: Syrup: Bromhexine 4 mg + Dextromethorphan Hydrobromide 5 mg per 5 mL.
Dosage Information
| Adult Dosage | The usual adult dose is 5-10 mL (one to two teaspoons) three to four times a day, or as directed by a physician. The dose may vary depending on the severity of symptoms and the patient's response. Do not exceed 40 mL in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and consider a lower dose. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | Adults: Do not exceed 40 mL in 24 hours. Each 5 mL contains Bromhexine 4 mg and Dextromethorphan Hydrobromide 5 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of imcuf dmr syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| SSRIs | Major | |
| CYP2D6 inhibitors | Major | |
| CNS depressants | Moderate | |
| Alcohol | Moderate | |
| Antihistamines | Moderate | |
| Amiodarone | Moderate | |
| Antacids | Minor | |
| Diuretics | Minor | |
| Warfarin | Minor |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- SSRIs (e.g., fluoxetine, paroxetine)
- CYP2D6 inhibitors (e.g., quinidine, terbinafine)
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids, alcohol)
- Antihistamines (sedating)
- Amiodarone
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine because it can enhance the sedative effects of dextromethorphan and increase the risk of drowsiness, dizziness, and respiratory depression. It may also worsen stomach irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to bromhexine, dextromethorphan, or any component of the formulation.","Concurrent use with MAO inhibitors or within 14 days of stopping MAO inhibitors.","Children under 12 years of age (unless prescribed by a doctor).","Chronic cough associated with smoking, asthma, or emphysema.","Cough with excessive secretions."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Avoid driving or operating machinery if you feel drowsy.","Do not use for persistent or chronic cough without medical advice.","Use with caution in patients with liver or kidney disease.","Use with caution in patients with a history of drug abuse or addiction.","Do not use in children under 12 years without medical advice.","Consult a doctor if cough persists for more than 7 days or is accompanied by fever, rash, or persistent headache."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, drowsiness, dizziness, hallucinations, confusion, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Avoid driving or operating heavy machinery if you feel drowsy or dizzy after taking this medicine. Do not consume alcohol while on this medicine as it can increase drowsiness and impair judgment. Inform your doctor if you have a history of liver disease, kidney disease, asthma, or chronic bronchitis. Do not use this medicine for a persistent or worsening cough without medical evaluation. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and confusion. Use with caution and consider a lower dose. Regular monitoring for adverse effects is advised.
🤰 Pregnancy Planning (TTC)
Not established from the available information. Consult your doctor before planning pregnancy or if you are pregnant.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may cause dry mouth or interact with anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel drowsy or dizzy after taking this medicine. Light activities are generally safe, but listen to your body and rest if needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your job involves operating heavy machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, worsens, or is accompanied by fever, rash, or persistent headache. Do not stop abruptly if you have been taking it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of dextromethorphan can lead to tolerance, dependence, and withdrawal symptoms. Bromhexine long-term use may cause gastrointestinal discomfort. Regular monitoring of liver and kidney function may be required if used for extended periods under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and soothe airways.
Evidence: Commonly used, supportive careSoothes throat irritation and reduces cough.
Evidence: Traditionally used, may provide symptomatic reliefSoothes cough and throat irritation.
Evidence: Some evidence for cough relief in adults and children over 1 year💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing if you are due for any vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, continue with your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after oral administration. You may notice relief from cough and easier mucus clearance within a few hours.
A: Do not take this medicine with other cough suppressants or mucolytics without consulting your doctor, as it may lead to overdose or increased side effects.
A: This medicine is intended for short-term symptomatic relief only. Prolonged use should be avoided unless advised by a doctor.
🤔 Common Patient Concerns
🔄 Substitutes for imcuf dmr syrup
View AllAlternative brands with exact same active ingredient:
-
vistadex capsuleCadila Pharmaceuticals Ltd ₹10.31 67.7% CHEAPER
-
vistadex syrupCadila Pharmaceuticals Ltd ₹14.65 54% CHEAPER
-
p dex syrupMen-Care Pharmaceuticals ₹20.00 37.3% CHEAPER
-
ascodex cough syrupGlenmark Pharmaceuticals Ltd ₹21.68 32% CHEAPER
-
aldrex syrupAlkem Laboratories Ltd ₹25.78 19.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for symptomatic relief of dry and productive cough. It does not treat the underlying cause. - Myth: It is safe to take this medicine for a long time.
Fact: This medicine is for short-term use only. Prolonged use without medical supervision can be harmful. - Myth: This medicine is safe for children of all ages.
Fact: This medicine is not recommended for children under 12 years without medical advice.
🔄 Alternative Options
Generic Alternatives
- Bromhexine + Dextromethorphan Hydrobromide syrup (various manufacturers)