ibuclin p 100mg oral suspension - Mefenamic Acid (100mg/5ml) medicine

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🏭 Dr Reddy's Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like mefenamic acid are generally avoided during pregnancy, especially in the third trimester, due to risks of premature closure of the ductus arteriosus and other complications. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term pain relief and fever reduction.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is ibuclin p 100mg oral suspension used for?

This medicine is an oral suspension of mefenamic acid, an NSAID used to relieve mild to moderate pain, menstrual cramps, and fever. It works by blocking prostaglandins. Take it with food and avoid alcohol.

  • Generic Name: Mefenamic Acid (100mg/5ml)
  • Manufacturer: Dr Reddy's Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ibuclin p 100mg oral suspension के बारे में (Hindi Summary)

उपयोग: यह दवा मेफेनामिक एसिड का एक ओरल सस्पेंशन है, जिसका उपयोग हल्के से मध्यम दर्द, मासिक धर्म में होने वाले ऐंठन, दांत दर्द, सिरदर्द और बुखार को कम करने के लिए किया जाता है। यह सूजन को भी कम करती है। इसे भोजन के साथ लें और शरूरत से ज्यादा न लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक या अवधि से अधिक न लें। पेट की परेशानी कम करने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब न पिएं। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी है, तो डॉक्टर को बताएं। गर्भवती महिलाएं बिना डॉक्टर की सलाह के इसका उपयोग न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 ibuclin p 100mg oral suspension Uses & Benefits

[{"condition":"Menstrual cramps (dysmenorrhea)","description":"Relieves pain and inflammation associated with menstrual periods.","evidence":"Well-established"},{"condition":"Mild to moderate pain","description":"Effective for dental pain, headache, muscle aches, and joint pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever by acting on the hypothalamus.","evidence":"Well-established"},{"condition":"Osteoarthritis and rheumatoid arthritis","description":"Helps reduce pain and inflammation in joints.","evidence":"Established"},{"condition":"Postoperative pain","description":"Used for short-term pain relief after surgery.","evidence":"Established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used to relieve acute migraine attacks.","evidence":"Limited"},{"condition":"Prevention of preterm labor","description":"Occasionally used to delay premature labor, but not standard.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation

Also treats: Menstrual cramps, Fever, Osteoarthritis, Rheumatoid arthritis, Dental pain

📋 Drug Information

Generic Name(s)Mefenamic Acid (100mg/5ml)
Brand Nameibuclin p 100mg oral suspension
ManufacturerDr Reddy's Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (fenamates)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine with food or milk to minimize gastrointestinal irritation.
2
Limit the duration of use to the shortest time necessary to control symptoms.
3
Avoid prescribing to patients with a history of peptic ulcer disease or NSAID-induced asthma.
4
Monitor kidney function and blood pressure in patients on long-term therapy.
5
Warn patients about the increased risk of bleeding if they are on anticoagulants.
6
Advise patients to avoid alcohol while taking this medicine.
7
Consider alternative analgesics in elderly patients to reduce the risk of adverse effects.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Menstrual cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Dental pain
This medicine can relieve dental pain.
Likely Use
✅
Fever
This medicine helps reduce fever.
Likely Use
✅
Chronic joint pain
This medicine may be used for short-term relief.
Likely Use
❌
Chest pain
This medicine is not for chest pain; seek emergency care.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMefenamic acid is rapidly absorbed from the gastrointestinal tract after oral administration. The suspension formulation may be absorbed slightly faster than solid dosage forms.
DistributionIt is distributed widely in the body, with high concentrations in the liver, lungs, kidneys, and spleen. It crosses the placenta and is excreted in breast milk.
Protein BindingMefenamic acid is highly bound to plasma proteins (approximately 90%).
MetabolismIt is metabolized in the liver, primarily by cytochrome P450 enzymes (CYP2C9), to inactive metabolites.
Half-LifeThe elimination half-life is approximately 2 to 4 hours.
ExcretionMetabolites are excreted mainly in the urine (about 50-60%) and feces (about 20-25%).
BioavailabilityThe oral bioavailability is approximately 80-90%.
Onset of ActionPain relief typically begins within 1 to 2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations are reached about 2 to 4 hours after ingestion.
Duration of ActionThe analgesic effect lasts approximately 4 to 6 hours.

How It Works

This medicine works by reversibly inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins from arachidonic acid. Prostaglandins are mediators of pain, inflammation, and fever. By blocking their production, mefenamic acid reduces pain, swelling, and fever. It also inhibits prostaglandin synthesis in the uterus, which helps relieve menstrual cramps.

Mechanism Steps

1
Inhibition of cyclooxygenase: Mefenamic acid binds to and inhibits the COX-1 and COX-2 enzymes.
2
Reduced prostaglandin synthesis: This inhibition decreases the production of prostaglandins from arachidonic acid.
3
Decreased pain and inflammation: Lower prostaglandin levels reduce pain perception and inflammatory responses.
4
Fever reduction: Prostaglandins also affect the hypothalamus; their reduction leads to lowering of fever.

💡 How to Take ibuclin p 100mg oral suspension

Strength: Suspension: 100 mg per 5 ml.

1Shake the bottle well before each use.
2Measure the dose accurately using the provided measuring cup or syringe.
3Take with food or milk to reduce stomach upset.
4Swallow the suspension directly; do not mix with other liquids unless instructed.
5Follow the prescribed dosing schedule.
6Do not exceed the recommended dose or duration.

Dosage Information

Adult DosageThe usual adult dose for pain and fever is 250-500 mg every 6-8 hours as needed, not to exceed 1500 mg per day. For menstrual cramps, the dose may be 500 mg initially, followed by 250 mg every 6 hours if needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily Dose1500 mg per day for adults.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.
Caffeine
Limit
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ibuclin p 100mg oral suspension

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated. If vomiting is severe or persistent, seek medical advice.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If pain is severe, contact your doctor.
Heartburn (Common (5-10%))
Take with food. Avoid lying down immediately after taking. Consult doctor if persistent.
Diarrhea (Common (5-10%))
Drink plenty of fluids. If diarrhea is severe or contains blood, seek medical attention.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if it persists.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or unusual, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Drowsiness (Common (5-10%))
Avoid driving or operating heavy machinery. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report persistent stomach pain, especially if it worsens after eating. Immediate medical evaluation is needed.
Kidney problems (Rare (<0.1%))
Watch for decreased urine output, swelling, or fatigue. Contact your doctor immediately if these occur.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue. Seek medical attention.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience rash, swelling of face, lips, tongue, or throat, or difficulty breathing.
Blood disorders (Rare (<0.1%))
Report unusual bleeding, bruising, or signs of infection. A blood test may be needed.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, fever, and sensitivity to light.
Pancreatitis
Seek immediate care for severe abdominal pain that may radiate to the back, with nausea and vomiting.
Stevens-Johnson syndrome
Seek emergency help for rash, blisters, or peeling skin, especially with fever.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Aspirin Major
Other NSAIDs Major
Corticosteroids Major
Lithium Major
Methotrexate Major
ACE inhibitors Moderate
Diuretics Moderate
SSRIs Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Other NSAIDs
  • Corticosteroids
  • Anticoagulants (e.g., heparin, clopidogrel)
  • Lithium
  • Methotrexate
  • ACE inhibitors
  • Diuretics
  • SSRIs

⚡ Moderate Interactions

  • Beta-blockers
  • Cyclosporine
  • Digoxin
  • Oral hypoglycemics

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can worsen stomach irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to mefenamic acid or other NSAIDs","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe kidney disease","Severe liver disease","Heart failure","Third trimester of pregnancy","Children under 14 years (unless directed by a doctor)"]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of gastrointestinal bleeding.","May impair ability to drive or operate machinery.","Consult doctor before use if you have asthma, kidney disease, liver disease, or heart disease.","Do not take if you are pregnant or breastfeeding without medical advice."]

🤱 Lactation Safety

Mefenamic acid is excreted in breast milk. Limited data suggest it may be safe for short-term use, but consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, drowsiness, and in severe cases, seizures, kidney failure, or coma. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not use this medicine for more than 7 days unless directed by a doctor. If you have a history of stomach ulcers, kidney disease, liver disease, or heart failure, inform your doctor before use. Do not take this medicine if you are allergic to mefenamic acid, aspirin, or other NSAIDs. Pregnant women should avoid this medicine, especially during the third trimester, unless prescribed. Breastfeeding mothers should consult their doctor before use. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for postoperative pain, but it can increase the risk of bleeding. Consult your surgeon before use, especially after procedures with a high risk of bleeding.

🦷 Dental Procedures

This medicine can be used for dental pain, but it may increase bleeding risk during dental procedures. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods in your diet, such as fruits and vegetables.
🧘
Get adequate sleep to help your body recover.
🌞
Stay hydrated throughout the day.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase the risk of bleeding or injury while taking this medicine. Listen to your body and rest if you feel dizzy or tired.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed and fried foods.
Stay well hydrated.
Eat small, frequent meals if you experience stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, or allergic reactions. Do not stop abruptly if you are on a prescribed regimen without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and cardiovascular events. Regular monitoring of kidney and liver function is advised. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain management.

Evidence: Well-established
Heat therapy

Applying heat to affected areas can help relieve menstrual cramps and muscle pain.

Evidence: Established
Relaxation techniques

Yoga and meditation can help manage pain and stress.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, if you are scheduled for vaccination, inform your doctor about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 28-year-old woman with severe menstrual cramps
She was prescribed this medicine for dysmenorrhea. She took it with food as directed and experienced significant relief within 2 hours. She noted that taking it with food prevented stomach upset.
💡 Lesson: Taking this medicine with food improves tolerability and ensures effective pain relief.
👤 A 45-year-old man with dental pain
He used this medicine for a toothache while awaiting dental treatment. It relieved his pain effectively, but he experienced mild drowsiness. He was advised not to drive after taking it.
💡 Lesson: This medicine can cause drowsiness; avoid driving or operating machinery until you know how it affects you.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 1 to 2 hours after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

Q: Can I take it with other pain relievers?

A: Do not take with other NSAIDs unless directed by a doctor, as it increases the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ibuclin p 100mg oral suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Mefenamic acid is safe for long-term use.
    Fact: Mefenamic acid is intended for short-term use only. Long-term use increases the risk of serious side effects.
  • Myth: You can take mefenamic acid on an empty stomach.
    Fact: It should be taken with food or milk to reduce stomach upset.
  • Myth: Mefenamic acid is safe during pregnancy.
    Fact: It is generally avoided during pregnancy, especially in the third trimester, unless prescribed by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Mefenamic acid suspension (generic)

Brand Alternatives

  • Meftal-P Suspension
  • Mefkind Suspension
  • Mefanorm Suspension

📊 Comparison with Similar Medicines

[{"medicine":"Mefenamic acid","class":"NSAID","uses":"Pain, fever, menstrual cramps","common_side_effects":"Nausea, stomach pain, dizziness"},{"medicine":"Ibuprofen","class":"NSAID","uses":"Pain, fever, inflammation","common_side_effects":"Stomach pain, heartburn, nausea"},{"medicine":"Paracetamol","class":"Analgesic/antipyretic","uses":"Pain, fever","common_side_effects":"Rare at recommended doses"}]

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