ibiran syrup - Ranitidine (75mg/5ml) medicine

Ranidom PD 75mg/5ml Syrup: Complete Medicine Guide

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🏭 Indiabulls pharmaceutical ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Ranitidine is considered safe for use in pregnancy when clearly needed. It is classified as FDA Pregnancy Category B. However, consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain
  • Difficulty breathing or swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising
  • Confusion or hallucinations
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is ibiran syrup used for?

Ranidom PD 75mg/5ml syrup is a ranitidine oral syrup used to treat acid reflux, heartburn, and peptic ulcers by reducing stomach acid production. It is suitable for children and adults who cannot swallow tablets.

  • Generic Name: Ranitidine (75mg/5ml)
  • Manufacturer: Indiabulls pharmaceutical ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ibiran syrup के बारे में (Hindi Summary)

उपयोग: यह दवा रैनिटिडीन सिरप है जो पेट में एसिड बनने को कम करती है। इसका उपयोग सीने में जलन, एसिड रिफ्लक्स, गैस्ट्रोएसोफेगल रिफ्लक्स डिजीज और पेट के अल्सर के इलाज में किया जाता है। यह उन बच्चों और बड़ों के लिए उपयुक्त है जो गोली निगल नहीं सकते। यह दवा पेट के एसिड को कम करके लक्षणों से राहत देती है।

साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित मानी जाती है। कुछ लोगों को सिरदर्द, चक्कर आना, कब्ज, दस्त, जी मिचलाना और पेट में असहजता हो सकती है। ये दुष्प्रभाव हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको भ्रम, मतली, पेट में तेज दर्द, पीलिया, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक बढ़ाएं नहीं। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। मापने के लिए दी गई सिरिंज या कप का ही उपयोग करें। अगर आपको किडनी या लीवर की समस्या है तो डॉक्टर को बताएं। इस दवा के साथ शराब न पिएं। 14 दिनों से अधिक बिना डॉक्टर की सलाह के न लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 ibiran syrup Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces stomach acid and relieves symptoms such as heartburn and acid regurgitation.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Helps heal duodenal and gastric ulcers by reducing acid secretion.","evidence":"Well-established"},{"condition":"Heartburn and acid indigestion","description":"Provides short-term relief from episodic heartburn and indigestion.","evidence":"Well-established"},{"condition":"Zollinger-Ellison syndrome","description":"Used to manage excessive gastric acid secretion in this rare condition.","evidence":"Established"},{"condition":"Prevention of stress ulcers","description":"May be used in critically ill patients to prevent stress-related mucosal bleeding.","evidence":"Established"}]

Off-label uses: [{"condition":"Anaphylaxis adjunct","description":"Sometimes used as an adjunct to epinephrine and antihistamines in the emergency treatment of anaphylaxis.","evidence":"Limited"},{"condition":"Warts","description":"Occasionally used in topical or intralesional form for treating warts, but this is not a standard use for the oral syrup.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease

Also treats: Peptic ulcer disease, Heartburn, Zollinger-Ellison syndrome

📋 Drug Information

Generic Name(s)Ranitidine (75mg/5ml)
Brand Nameibiran syrup
ManufacturerIndiabulls pharmaceutical ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassH2 Receptor Blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Shake the bottle well before each use to ensure the medicine is evenly mixed.
2
Use a proper measuring device to avoid inaccurate dosing.
3
Take this medicine at the same time each day to maintain consistent levels.
4
If you are taking antacids, separate them by at least 1 hour from this medicine.
5
Report any unusual bruising, bleeding, or persistent headache to your doctor.
6
Do not use this medicine for longer than 14 days without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn
This medicine is commonly prescribed for this.
Likely Use
✅
Acid regurgitation
This medicine helps reduce acid reflux.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRanitidine is rapidly absorbed after oral administration. The oral bioavailability is approximately 50% to 60% due to first-pass metabolism. Food does not significantly affect the extent of absorption but may slightly delay the time to peak concentration.
DistributionRanitidine is widely distributed throughout the body, including into breast milk and cerebrospinal fluid. It has a volume of distribution of approximately 1.4 L/kg. It crosses the placenta.
Protein BindingApproximately 15% bound to plasma proteins.
MetabolismRanitidine undergoes hepatic metabolism to a small extent. The primary metabolites are N-oxide, S-oxide, and desmethyl ranitidine. The majority of the drug is excreted unchanged in the urine.
Half-LifeThe elimination half-life is approximately 2 to 3 hours in healthy adults. It is prolonged in patients with renal impairment.
ExcretionRanitidine is primarily excreted unchanged in the urine (about 70% of an oral dose). The remainder is excreted in feces. Renal clearance is the major route of elimination.
BioavailabilityThe oral bioavailability of ranitidine is approximately 50% to 60%.
Onset of ActionAcid suppression begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached 1 to 3 hours after oral administration.
Duration of ActionThe duration of acid suppression is approximately 8 to 12 hours.

How It Works

Ranitidine is a competitive, reversible inhibitor of histamine at the H2 receptors located on gastric parietal cells. By blocking these receptors, it reduces the production of gastric acid, including both basal and stimulated secretions. This leads to decreased gastric volume, lower hydrogen ion concentration, and reduced pepsin output. The effect is dose-dependent and helps in healing ulcers and relieving reflux symptoms.

Mechanism Steps

1
Binding to H2 receptors: Ranitidine binds competitively to histamine H2 receptors on the basolateral membrane of gastric parietal cells.
2
Blockade of histamine action: This binding prevents histamine from stimulating the parietal cells, thereby reducing intracellular cyclic AMP levels.
3
Reduced acid secretion: The decrease in cyclic AMP leads to reduced activity of the proton pump and less hydrogen ion secretion into the stomach.
4
Clinical effect: Gastric acid production falls, allowing ulcers to heal and reducing symptoms of reflux and heartburn.

💡 How to Take ibiran syrup

Strength: Each 5 mL of syrup contains 75 mg of ranitidine.

1Shake the bottle well before each use.
2Use the measuring cup or syringe provided to measure the correct dose.
3Take the medicine orally, with or without food.
4If you are taking it once daily, take it at bedtime.
5Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose for active duodenal ulcer is 150 mg twice daily or 300 mg at bedtime. For maintenance, 150 mg at bedtime. For GERD, 150 mg twice daily. For heartburn, 75 mg to 150 mg as needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Start with lower doses and monitor for side effects.
Renal ImpairmentIn patients with renal impairment, the dose should be reduced. For creatinine clearance less than 50 mL/min, the usual dose is 150 mg every 24 hours. Further adjustment may be needed.
Hepatic ImpairmentNo specific dose adjustment is generally required for hepatic impairment, but use with caution and monitor.
Maximum Daily DoseThe maximum recommended daily dose is 300 mg for most indications, but may be higher in Zollinger-Ellison syndrome under medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May take with or without food
Food does not significantly affect absorption.
Spicy foods
Avoid
May worsen heartburn and acid reflux.
Alcohol
Avoid
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ibiran syrup

✅ Common Side Effects

Headache (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Dizziness (Common (1-10%))
Avoid driving or operating machinery if you feel dizzy. Consult your doctor if it continues.
Constipation (Common (1-10%))
Increase fiber and fluid intake. Consult your doctor if it persists.
Diarrhea (Common (1-10%))
Stay hydrated. Consult your doctor if it is severe or persistent.
Nausea (Common (1-10%))
Take with food. Consult your doctor if it continues.

🚨 Serious Side Effects

Confusion (Rare (<0.1%))
Seek immediate medical attention, especially in elderly patients or those with kidney disease.
Hallucinations (Rare (<0.1%))
Discontinue and seek immediate medical help.
Thrombocytopenia (Rare (<0.1%))
Report unusual bruising or bleeding to your doctor immediately.
Hepatitis (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Anaphylaxis (Very rare (<0.01%))
Call emergency services immediately if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Agranulocytosis
Seek immediate medical attention if you develop fever, sore throat, or mouth ulcers.
Pancytopenia
Report unusual tiredness, infections, or bleeding to your doctor.
Pancreatitis
Seek immediate medical attention for severe abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Atazanavir Major
Warfarin Moderate
Metformin Moderate
Glipizide Moderate
Antacids Minor
Sucralfate Minor

🚨 Major Interactions

  • Ketoconazole
  • Atazanavir

⚡ Moderate Interactions

  • Warfarin
  • Metformin
  • Glipizide

🍷 Alcohol Interaction

Alcohol may increase stomach irritation and worsen the condition being treated. It is advisable to avoid or limit alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ranitidine or other H2 receptor antagonists","History of acute porphyria"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose reduction may be necessary.","Use with caution in patients with hepatic impairment.","Elderly patients may be more susceptible to confusion and other central nervous system effects.","Avoid use in patients with a history of porphyria.","Do not exceed recommended dose or duration without medical advice.","Consult a doctor if symptoms persist or worsen after 14 days of treatment."]

🤱 Lactation Safety

Ranitidine is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, dizziness, and drowsiness. Treatment is supportive and symptomatic. Contact a poison control center or emergency room immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring device such as a syringe or cup provided with the product, not a household spoon. If you have kidney or liver problems, your doctor may need to adjust your dose. Avoid alcohol while taking this medicine because it can worsen stomach irritation. Do not use this medicine for more than 14 days without consulting a doctor. Keep this medicine out of the reach of children. Store it at room temperature, away from direct sunlight and moisture. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to confusion and other central nervous system side effects. Dose adjustment may be needed based on kidney function.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Ranitidine is generally considered safe in pregnancy, but medical advice is recommended.

🏥 Post-Surgery Considerations

This medicine may be used to prevent stress ulcers after surgery. Follow your doctor's instructions regarding dosing and duration.

🦷 Dental Procedures

No specific precautions are required for dental procedures, but inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Avoid spicy, fatty, and acidic foods that can trigger heartburn.
🥗
Eat smaller, more frequent meals instead of large ones.
😴
Do not lie down immediately after eating; wait at least 2 hours.
💧
Elevate the head of your bed to reduce nighttime reflux.
🧘
Maintain a healthy weight and avoid tight clothing.
🌞
Quit smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Avoid vigorous exercise immediately after meals as it may worsen reflux. Light to moderate exercise is generally safe.

🥗 Diet Recommendations

Include fiber-rich foods like fruits, vegetables, and whole grains.
Avoid caffeine, chocolate, and mint which can relax the lower esophageal sphincter.
Stay well hydrated with water.
Limit carbonated beverages.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It generally does not affect your ability to work.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, especially if you are being treated for an ulcer. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to vitamin B12 deficiency and increased risk of bone fractures. It should be used at the lowest effective dose for the shortest duration. Regular monitoring may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Dietary changes, weight loss, and elevating the head of the bed can help reduce reflux symptoms.

Evidence: Well-established
Proton pump inhibitors

Another class of acid-suppressing medicines that may be used if H2 blockers are not effective.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, adjust dosing times gradually under medical guidance. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 6-year-old child with frequent heartburn and acid reflux
The child was prescribed this medicine by a pediatrician. The parents administered it using the provided syringe, twice daily. Within a week, the child's symptoms improved significantly. The parents were advised to avoid giving the child spicy and acidic foods.
💡 Lesson: Proper administration and dietary modifications enhance the effectiveness of this medicine in children.
👤 A 45-year-old adult with peptic ulcer disease
The patient was prescribed this medicine along with lifestyle changes. He took it regularly for 8 weeks. His ulcer healed, and symptoms resolved. He was advised to avoid alcohol and smoking.
💡 Lesson: Adherence to prescribed therapy and lifestyle modifications are key to ulcer healing.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts reducing acid within 30 to 60 minutes after oral administration.

Q: Can I take it with food?

A: Yes, it can be taken with or without food. Food does not significantly affect its absorption.

Q: Is it safe for children?

A: It can be used in children under medical supervision. The dose is determined by the pediatrician based on the child's weight and condition.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ibiran syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Ranidom PD is a painkiller.
    Fact: It is not a painkiller; it reduces stomach acid.
  • Myth: Ranidom PD can be taken indefinitely.
    Fact: Long-term use should be under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Ranitidine oral syrup

Brand Alternatives

  • Zantac
  • Aciloc
  • Rantac

📊 Comparison with Similar Medicines

[{"medicine":"Ranitidine","class":"H2 blocker","onset":"30-60 min","duration":"8-12 hours"},{"medicine":"Famotidine","class":"H2 blocker","onset":"30-60 min","duration":"10-12 hours"},{"medicine":"Omeprazole","class":"Proton pump inhibitor","onset":"1-2 hours","duration":"24 hours"}]

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