ib-gluta infusion - L-alanyl-L-glutamine (20gm) medicine

Elemune 20gm Infusion: Complete Medicine Guide

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🏭 Fusion Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for parenteral nutrition supplementation; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe allergic reaction with rash, itching, or hives
  • Chest pain or irregular heartbeat
  • Confusion, lethargy, or seizures
  • Decreased urine output or swelling in the legs
  • Severe abdominal pain or vomiting blood
  • Yellowing of the skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is ib-gluta infusion used for?

This medicine is an intravenous infusion of L-alanyl-L-glutamine, used to provide glutamine to patients who cannot eat enough. It supports gut health, immune function, and muscle maintenance during illness or recovery.

  • Generic Name: L-alanyl-L-glutamine (20gm)
  • Manufacturer: Fusion Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ib-gluta infusion के बारे में (Hindi Summary)

उपयोग: यह दवा एल-एलेनिल-एल-ग्लूटामाइन का इंट्रावेनस इन्फ्यूजन है, जिसका उपयोग उन मरीजों में किया जाता है जो मुंह से पर्याप्त भोजन नहीं कर पाते या जिन्हें ग्लूटामाइन की अतिरिक्त आवश्यकता होती है। यह आंतों की सेहत, प्रतिरक्षा प्रणाली और मांसपेशियों को बनाए रखने में मदद करती है। यह गंभीर बीमारी, सर्जरी या आघात से उबरने वाले मरीजों के लिए दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में असहजता और दस्त शामिल हैं। कुछ मरीजों को सिरदर्द, चक्कर आना या धातु जैसा स्वाद महसूस हो सकता है। इंजेक्शन की जगह पर लालिमा, सूजन या दर्द हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई या इलेक्ट्रोलाइट असंतुलन हो सकता है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में योग्य स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों, विशेषकर गुर्दे या यकृत की बीमारी, और किसी भी एलर्जी के बारे में बताएं। इलाज के दौरान डॉक्टर आपके गुर्दे, यकृत, इलेक्ट्रोलाइट और तरल संतुलन की निगरानी करेंगे। यदि घोल धुंधला या कणों युक्त हो तो उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ib-gluta infusion Uses & Benefits

[{"condition":"Parenteral nutrition supplementation","description":"Provides glutamine to patients who cannot eat or absorb enough nutrients orally or enterally, supporting gut integrity and immune function.","evidence":"Well-established"},{"condition":"Critical illness and catabolic states","description":"Helps maintain muscle mass and supports recovery in patients with severe burns, trauma, or sepsis who are under metabolic stress.","evidence":"Moderate"},{"condition":"Post-operative recovery","description":"Used after major surgery to support healing and reduce complications related to gut barrier dysfunction.","evidence":"Moderate"},{"condition":"Short bowel syndrome","description":"May aid in intestinal adaptation and nutrient absorption in patients with compromised gut function.","evidence":"Limited"}]

Off-label uses: [{"condition":"Chemotherapy-induced mucositis","description":"Sometimes used off-label to reduce severity of oral and gastrointestinal mucositis in cancer patients undergoing chemotherapy.","evidence":"Limited"},{"condition":"Sickle cell disease","description":"Investigated for its potential to reduce oxidative stress and improve endothelial function, but not standard practice.","evidence":"Limited"}]

Primary treatment for: Nutritional deficiency requiring parenteral glutamine supplementation

Also treats: Critical illness, Post-operative recovery, Short bowel syndrome, Malnutrition

📋 Drug Information

Generic Name(s)L-alanyl-L-glutamine (20gm)
Brand Nameib-gluta infusion
ManufacturerFusion Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAmino acids
Route of AdministrationParenteral (intravenous infusion)
StorageStore at room temperature (15-30°C). Do not freeze. Keep in the original container until use. Protect from light.
Shelf LifeRefer to the product packaging for the expiration date. Do not use after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only in a clinical setting with proper monitoring.
2
Assess renal and hepatic function before starting the infusion.
3
Monitor electrolyte levels and fluid balance daily during treatment.
4
Slow the infusion rate if the patient experiences nausea or vomiting.
5
Do not add other medications to the infusion bag unless specifically instructed.
6
Watch for signs of allergic reactions and stop the infusion immediately if they occur.
7
Ensure the solution is clear and free of particles before use.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Inability to eat or absorb nutrients
This medicine is used when oral or enteral nutrition is insufficient.
Likely Use
✅
Severe malnutrition
It provides glutamine to support nutritional status.
Likely Use
❌
Mild fatigue
This medicine is not a general energy booster.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered intravenously, so absorption is not applicable. The dipeptide is directly introduced into the systemic circulation.
DistributionAfter intravenous administration, L-alanyl-L-glutamine is rapidly distributed throughout the body. It is hydrolyzed in the bloodstream, and the released glutamine and alanine are taken up by tissues with high demand, such as the intestines, liver, kidneys, and immune cells. Glutamine is the most abundant free amino acid in plasma and muscle.
Protein BindingNot established from the available information.
MetabolismL-alanyl-L-glutamine is metabolized by dipeptidases in the plasma and on the surface of endothelial cells, releasing free glutamine and alanine. Glutamine is further metabolized in various tissues to glutamate, ammonia, and other metabolites. Alanine is primarily metabolized in the liver via gluconeogenesis.
Half-LifeThe dipeptide L-alanyl-L-glutamine has a very short half-life in plasma, typically less than 5 minutes, due to rapid hydrolysis. The released glutamine and alanine have longer half-lives, but specific values are not well established.
ExcretionThe metabolites of L-alanyl-L-glutamine, including urea and carbon dioxide, are excreted via the kidneys and lungs. Glutamine and alanine are largely reabsorbed or metabolized, with minimal unchanged excretion.
BioavailabilityBioavailability is 100% because this medicine is administered intravenously.
Onset of ActionThe effects of this medicine begin immediately after intravenous administration as the dipeptide is hydrolyzed and glutamine becomes available to tissues. Clinical effects on gut integrity and immune function may take days to become apparent.
Peak Plasma TimePeak plasma levels of glutamine and alanine occur shortly after the end of the infusion, typically within 30 minutes.
Duration of ActionThe duration of action depends on the infusion rate and the patient's metabolic state. Glutamine levels remain elevated for several hours after infusion, but the clinical effects on gut and immune function are sustained with continuous or repeated dosing.

How It Works

This medicine delivers L-alanyl-L-glutamine, which is rapidly hydrolyzed by dipeptidases in the bloodstream to release free glutamine and alanine. Glutamine is a key substrate for rapidly dividing cells such as enterocytes, colonocytes, and lymphocytes. It serves as a precursor for nucleotides, glutathione, and other important molecules. By providing exogenous glutamine, this medicine helps maintain gut mucosal integrity, supports immune function, and attenuates muscle protein breakdown during catabolic illness. Alanine released from the dipeptide can be used for gluconeogenesis, contributing to glucose homeostasis.

Mechanism Steps

1
Administration: This medicine is administered intravenously, delivering L-alanyl-L-glutamine directly into the bloodstream.
2
Hydrolysis: Plasma dipeptidases rapidly cleave the dipeptide into free glutamine and alanine.
3
Cellular uptake: Glutamine is taken up by cells via specific transporters, particularly in the gut, liver, and immune cells.
4
Metabolic utilization: Glutamine serves as a fuel source for enterocytes and lymphocytes, and as a precursor for nucleotides, glutathione, and amino sugars.
5
Physiological effects: The increased glutamine availability supports gut barrier integrity, immune function, and protein synthesis, helping to counteract catabolic states.

💡 How to Take ib-gluta infusion

Strength: 20 g of L-alanyl-L-glutamine per infusion bag (as a sterile solution for intravenous infusion).

1This medicine is administered by a healthcare professional in a hospital or clinic setting.
2The infusion is given intravenously, usually over 1 to 2 hours.
3Do not attempt to self-administer this medicine.
4Report any discomfort or unusual symptoms to your nurse or doctor immediately.
5Follow your healthcare provider's instructions regarding monitoring and follow-up.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 20 g of L-alanyl-L-glutamine (equivalent to approximately 13.46 g of L-glutamine) administered as an intravenous infusion once daily or as directed by a clinician. The dose may be adjusted based on the patient's clinical condition, nutritional requirements, and renal and hepatic function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal or hepatic function and may require dose adjustment. Use with caution and monitor closely.
Renal ImpairmentIn patients with renal impairment, dose reduction may be necessary. Contraindicated in severe renal impairment (creatinine clearance < 25 mL/min). Consult a clinician for individualized dosing.
Hepatic ImpairmentIn patients with hepatic impairment, dose reduction may be necessary. Contraindicated in severe hepatic dysfunction. Consult a clinician for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 20 g of L-alanyl-L-glutamine, but this may vary based on clinical judgment. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Not applicable
Not applicable
This medicine is given intravenously and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 A scheduled dose is missed in the hospital
→ Inform your nurse or doctor immediately.
💡 They will reschedule the dose as appropriate. Do not attempt to self-administer.

⚠️ Side Effects of ib-gluta infusion

✅ Common Side Effects

Nausea (Common (1-10%))
Slow the infusion rate or pause temporarily. Consult your doctor if it persists.
Vomiting (Common (1-10%))
Report to your nurse or doctor. Adjust infusion rate as advised.
Abdominal discomfort (Common (1-10%))
Usually resolves on its own. Inform your healthcare provider if severe.
Diarrhea (Common (1-10%))
Stay hydrated. Notify your doctor if it continues.
Injection site reactions (Common (1-10%))
Apply cold compress if needed. Report to nurse if redness or swelling worsens.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, difficulty breathing, or dizziness.
Severe electrolyte imbalance (Rare (<0.1%))
Requires immediate medical monitoring and correction. Report muscle weakness, confusion, or irregular heartbeat.
Fluid overload (Rare (<0.1%))
May cause swelling, shortness of breath, or weight gain. Inform your doctor immediately.
Hyperammonemia (Rare (<0.1%))
Can cause confusion, lethargy, or coma. Requires urgent medical attention.

⚠️ Rare Side Effects

Elevated liver enzymes
Monitor liver function tests. Report jaundice or abdominal pain.
Hypersensitivity reactions
Discontinue and seek medical advice if rash or fever occurs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

🚨 Major Interactions

  • None established

⚡ Moderate Interactions

  • None established

🍷 Alcohol Interaction

Alcohol consumption should be avoided while receiving this medicine, as alcohol can worsen dehydration, electrolyte imbalances, and liver stress. Consult your doctor for personalized advice.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe renal impairment (e.g., creatinine clearance < 25 mL/min)","Severe hepatic dysfunction","Known hypersensitivity to L-alanyl-L-glutamine or any component of the formulation","Inborn errors of amino acid metabolism","Severe metabolic acidosis"]

⚠️ Warnings & Precautions

["Administer only under medical supervision.","Monitor for signs of allergic reactions.","Use with caution in patients with renal or hepatic impairment.","Do not use if the solution is cloudy or contains particles.","Ensure proper aseptic technique during preparation.","Do not add other medications to the infusion bag unless instructed.","Monitor electrolyte levels and fluid balance regularly.","Avoid in patients with severe metabolic acidosis."]

🤱 Lactation Safety

It is not known whether L-alanyl-L-glutamine is excreted in human breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its administration by healthcare professionals. If overdose is suspected, stop the infusion and provide supportive care. Monitor electrolytes, renal function, and fluid status. There is no specific antidote. Contact a poison control center if needed.

⏰ Missed Dose

This medicine is administered by healthcare professionals in a clinical setting. If a dose is missed, it will be rescheduled by your healthcare team. Do not attempt to self-administer a missed dose.

Additional Safety Advice

General Safety

This medicine must be administered only by a qualified healthcare professional in a clinical setting. Do not attempt to self-administer this infusion. Inform your doctor about all your medical conditions, especially kidney or liver disease, and any allergies you have. Your doctor will monitor your kidney and liver function, electrolyte levels, and acid-base balance during treatment. Do not use this medicine if the solution is cloudy, discolored, or contains particles. Follow strict aseptic technique during preparation and administration to prevent infection. Do not add other medications to the infusion bag unless specifically instructed. Keep this medicine out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before receiving this medicine. Report any new or worsening symptoms to your healthcare provider immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal and hepatic function and may require dose adjustments. Monitor closely for side effects and electrolyte imbalances.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before receiving this medicine. Safety in pregnancy is not well established.

🏥 Post-Surgery Considerations

This medicine is often used after major surgery to support recovery and maintain gut integrity. It is administered under medical supervision.

🦷 Dental Procedures

No specific precautions are required for dental procedures while receiving this medicine, but inform your dentist about your treatment.

💚 Lifestyle Tips for Better Results

🏃
Follow your healthcare provider's advice on nutrition and hydration.
🥗
Engage in gentle physical activity as tolerated to support recovery.
😴
Get adequate rest to aid healing.
💧
Avoid alcohol while receiving this medicine.
🧘
Attend all scheduled follow-up appointments and monitoring tests.

🏋️ Exercise Considerations

Avoid strenuous exercise while receiving this medicine, especially if you are recovering from illness or surgery. Consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Follow a balanced diet as advised by your doctor or dietitian.
Include protein-rich foods to support healing when you can eat.
Stay well hydrated unless fluid restriction is advised.
Avoid alcohol and limit processed foods.

💼 Impact on Daily Work & Life

This medicine is administered in a healthcare setting, so it may require time away from work for treatment. Discuss your treatment schedule with your employer and plan for rest as needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your healthcare provider will determine when to stop based on your clinical condition and nutritional status.

📅 Long-Term Use Effects

Long-term use of this medicine should be monitored for potential effects on liver and kidney function, as well as electrolyte balance. Prolonged use without proper monitoring may lead to complications. Regular follow-up with your healthcare provider is essential to assess ongoing need and adjust treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral glutamine supplements

May be used if oral intake is possible and adequate, but not a substitute for intravenous therapy in severe cases.

Evidence: Limited
Enteral nutrition

Tube feeding may be an alternative if the gut is functional but oral intake is insufficient.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor regarding vaccination timing if you are immunocompromised or recovering from illness.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Keep in original container until use

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not use if solution is cloudy or contains particles

✈️ Traveling with This Medicine

This medicine is administered in a healthcare setting, so travel advice is limited. If you are traveling and need to continue treatment, ensure you have a copy of your prescription and a letter from your doctor explaining the medical need. Carry the medicine in its original packaging and store it at room temperature, away from direct sunlight. Check with your airline and destination country about regulations for carrying medical infusions. Arrange for administration by a qualified healthcare professional at your destination.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man recovering from major abdominal surgery
He was unable to eat for several days after surgery and was started on this medicine as part of his intravenous nutrition. His gut function improved, and he was able to transition to oral diet sooner than expected. He experienced mild nausea during the first infusion, which resolved when the rate was slowed.
💡 Lesson: This medicine can support recovery after surgery by maintaining gut health, but side effects like nausea can be managed by adjusting the infusion rate.
👤 A 45-year-old woman with short bowel syndrome
She required long-term parenteral nutrition and was given this medicine to support intestinal adaptation. Over several weeks, her ability to absorb nutrients improved, and she had fewer episodes of diarrhea. She was monitored closely for electrolyte imbalances.
💡 Lesson: Consistent use under medical supervision can help improve gut function in patients with short bowel syndrome, but regular monitoring is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The medicine starts working immediately after infusion, but clinical effects on gut and immune function may take several days to become noticeable.

Q: Can I drive after receiving this medicine?

A: This medicine is given in a clinical setting. You should not drive immediately after infusion if you feel dizzy or unwell. Follow your doctor's advice.

Q: Is this medicine safe during pregnancy?

A: Safety in pregnancy is not well established. Use only if clearly needed and prescribed by your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long will I need this infusion?
  • Will it affect my kidney function?
  • Can I eat normally while on this medicine?
  • What if I miss a dose?
  • Are there any long-term side effects?

🔄 Substitutes for ib-gluta infusion

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a general energy booster.
    Fact: It is a specialized nutritional supplement for patients with specific medical needs, not a general tonic.
  • Myth: It can be taken orally.
    Fact: It is formulated for intravenous infusion only and must be given by a healthcare professional.

📊 Comparison with Similar Medicines

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