advastat f 160mg/10mg tablet - Fenofibrate (160mg) + Rosuvastatin (10mg) medicine

advastat f 160mg/10mg tablet

4.7 (12 reviews)
🏭 Fusion Healthcare Pvt Ltd πŸ“¦ Varies by brand πŸ’Š Allopathy πŸ“… Updated: Aug 23, 2026
⚠️ Hepatotoxicity Risk πŸ“‹ Prescription Required πŸ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is advastat f 160mg/10mg tablet used for?

Arvast F 10 Tablet (Fenofibrate + Rosuvastatin) is used to treat CARDIAC. It contains Fenofibrate (160mg) + Rosuvastatin (10mg), which Fenofibrate: Activates PPARΞ±, increasing lipolysis and clearance of triglycerid. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Fenofibrate + Rosuvastatin
  • Manufacturer: Fusion Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
πŸ’‘ Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

πŸ’Š advastat f 160mg/10mg tablet Uses & Benefits

Hyperlipidemia, mixed dyslipidemia, prevention of cardiovascular events.

Off-label uses: Non-alcoholic fatty liver disease, diabetic dyslipidemia.

πŸ“‹ Drug Information

Generic Name(s)Fenofibrate + Rosuvastatin
Brand NameArvast F 10 Tablet
ManufacturerFusion Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassLipid-lowering agent (Fibrate + Statin)
Route of AdministrationOral
StorageStore at 20-25Β°C, protect from light and moisture.
Shelf LifeAs per manufacturer

πŸ”¬ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionFenofibrate: Well absorbed; Rosuvastatin: Well absorbed, food reduces rate but not extent.
DistributionFenofibrate: High plasma protein binding; Rosuvastatin: Extensive distribution, primarily to liver.
Protein BindingFenofibrate: 99%; Rosuvastatin: 88%
MetabolismFenofibrate: Hydrolyzed by esterases to fenofibric acid; Rosuvastatin: Minimal metabolism (CYP2C9, 2C19).
Half-LifeFenofibrate: 20 hours; Rosuvastatin: 19 hours
ExcretionFenofibrate: Urine (60%) and feces (25%); Rosuvastatin: Feces (90%) and urine (10%)
BioavailabilityFenofibrate: 30-60%; Rosuvastatin: 20%
Onset of ActionFenofibrate: 2-4 weeks; Rosuvastatin: 1 week
Peak Plasma TimeFenofibrate: 6-8 hours; Rosuvastatin: 3-5 hours
Duration of ActionFenofibrate: 24 hours; Rosuvastatin: 24 hours

How It Works

Fenofibrate: Activates PPARΞ±, increasing lipolysis and clearance of triglycerides; Rosuvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis.

Mechanism Steps

1Fenofibrate activates PPARΞ± receptors in liver and adipose tissue.
2PPARΞ± activation increases lipoprotein lipase activity, enhancing triglyceride clearance.
3Rosuvastatin competitively inhibits HMG-CoA reductase, reducing cholesterol synthesis.

πŸ’‘ How to Take advastat f 160mg/10mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of advastat f 160mg/10mg tablet

βœ… Common Side Effects

  • Headache
  • Myalgia
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Increased liver enzymes

🚨 Serious Side Effects

  • Rhabdomyolysis
  • Hepatotoxicity
  • Pancreatitis
  • Renal failure
  • Angioedema

⚠️ Rare Side Effects

  • Peripheral neuropathy
  • Tendon rupture
  • Interstitial lung disease
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

πŸ”¬ Drug Interactions

⚠️ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
Cyclosporine Major Increased rosuvastatin levels, risk of myopathy
Gemfibrozil Major Increased risk of rhabdomyolysis
Colchicine Major Increased risk of myopathy
Antacids Moderate Reduced rosuvastatin absorption
Ezetimibe Moderate Additive lipid-lowering effect
Niacin Moderate Increased risk of myopathy
Digoxin Moderate Possible increased digoxin levels
Oral contraceptives Moderate Increased estrogen levels
Vitamin K antagonists Minor Enhanced anticoagulant effect
Bile acid sequestrants Minor Reduced absorption of fenofibrate

🚨 Major Interactions

  • Warfarin
  • Cyclosporine
  • Gemfibrozil
  • Fibrates
  • Colchicine

⚑ Moderate Interactions

  • Antacids
  • Ezetimibe
  • Niacin
  • Digoxin
  • Oral contraceptives

ℹ️ Minor Interactions

  • Vitamin K antagonists
  • Bile acid sequestrants

🍽️ Food Interactions

Grapefruit juice may increase rosuvastatin levels; high-fat meals may reduce absorption.

🍷 Alcohol Interaction

Avoid excessive alcohol; may increase hepatotoxicity risk.

πŸ›‘οΈ Safety & Warnings

🚫 Contraindications

Active liver disease, unexplained persistent transaminase elevation, pregnancy, lactation, severe renal impairment, hypersensitivity.

πŸ“Š Monitoring Parameters

Lipid profile, liver function tests, renal function, creatine kinase, signs of myopathy.

🀱 Lactation Safety

Not recommended; excreted in milk.

πŸ’Š Overdose Management

Supportive care; no specific antidote; consider gastric lavage.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double.

πŸ‘¨β€βš•οΈ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

πŸ”— View Profile

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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