hyozen 20mg injection - Hyoscine butylbromide (20mg) medicine

Belic 20mg Injection: Complete Medicine Guide

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🏭 Zenlabs Ethica Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for primary uses.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe abdominal pain or distension
  • Rapid or irregular heartbeat
  • Inability to urinate
  • Severe eye pain or vision changes
  • Confusion or hallucinations
  • Injection site becomes painful, swollen, or dark

If experiencing severe symptoms, call emergency services immediately.

What is hyozen 20mg injection used for?

This medicine is an antispasmodic injection containing hyoscine butylbromide 20mg. It is used to relieve abdominal pain caused by spasms in the gastrointestinal, biliary, and urinary tracts. It works by relaxing smooth muscles. It is given by a healthcare professional as an intramuscular or intravenous injection.

  • Generic Name: Hyoscine butylbromide (20mg)
  • Manufacturer: Zenlabs Ethica Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 hyozen 20mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा हाइओसीन ब्यूटाइलब्रोमाइड 20mg इंजेक्शन है, जिसका उपयोग पेट, पित्त और मूत्र मार्ग की मांसपेशियों में ऐंठन के कारण होने वाले दर्द को कम करने के लिए किया जाता है। यह मांसपेशियों को आराम देकर ऐंठन को कम करती है। यह दवा डॉक्टर द्वारा इंजेक्शन के रूप में दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, चक्कर आना, धुंधली दृष्टि, मतली और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, तेज धड़कन, पेशाब रुकना आदि हो सकते हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। यदि आपको ग्लूकोमा, मायस्थेनिया ग्रेविस, हृदय रोग, या पेशाब रुकने की समस्या है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। इस दवा से चक्कर आ सकते हैं, इसलिए वाहन चलाने से बचें। शराब का सेवन न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 hyozen 20mg injection Uses & Benefits

[{"condition":"Abdominal pain due to spasms","description":"Relieves smooth muscle spasms in the gastrointestinal tract, reducing pain and discomfort.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Helps relax the biliary tract muscles, alleviating pain from gallstones or other biliary conditions.","evidence":"Well-established"},{"condition":"Renal colic","description":"Reduces spasms in the urinary tract, providing relief from pain associated with kidney stones.","evidence":"Well-established"},{"condition":"Irritable bowel syndrome (IBS)","description":"Used to manage abdominal cramping and pain associated with IBS.","evidence":"Moderate"},{"condition":"Pre-procedural bowel relaxation","description":"Administered before certain diagnostic procedures like endoscopy or colonoscopy to reduce bowel movements.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Menstrual cramps","description":"Sometimes used off-label to relieve severe menstrual cramps due to its antispasmodic properties.","evidence":"Limited"},{"condition":"Biliary dyskinesia","description":"May be used off-label to manage pain from biliary dyskinesia, a functional disorder of the gallbladder.","evidence":"Limited"}]

Primary treatment for: Abdominal spasms

Also treats: Biliary colic, Renal colic, Irritable bowel syndrome

📋 Drug Information

Generic Name(s)Hyoscine butylbromide (20mg)
Brand Namehyozen 20mg injection
ManufacturerZenlabs Ethica Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAnticholinergics
Route of AdministrationParenteral (intramuscular or intravenous injection)
StorageStore below 25°C, protected from light. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only by intramuscular or intravenous route as prescribed.
2
Monitor heart rate and blood pressure during administration.
3
Use with caution in elderly patients due to increased risk of anticholinergic effects.
4
Avoid concurrent use with other anticholinergic drugs to prevent additive effects.
5
Inform patients about potential dizziness and advise against driving.
6
Assess renal and hepatic function before repeated dosing.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Biliary colic
This medicine helps relieve pain from biliary spasms.
Likely Use
✅
Renal colic
This medicine reduces spasms in the urinary tract.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter intramuscular injection, hyoscine butylbromide is rapidly absorbed. After intravenous administration, it is immediately available in the bloodstream. The absolute bioavailability is high due to direct systemic administration.
DistributionHyoscine butylbromide is distributed throughout the body but does not readily cross the blood-brain barrier due to its quaternary ammonium structure. It has a volume of distribution of approximately 1.2 L/kg. It crosses the placenta and is excreted in breast milk in small amounts.
Protein BindingHyoscine butylbromide is minimally bound to plasma proteins (less than 10%).
MetabolismHyoscine butylbromide is primarily metabolized in the liver by hydrolysis and conjugation. The exact metabolic pathways are not fully characterized.
Half-LifeThe elimination half-life is approximately 2 to 3 hours after intravenous administration and about 4 to 5 hours after intramuscular administration.
ExcretionHyoscine butylbromide is excreted mainly in the urine and feces as unchanged drug and metabolites. About 50% of the dose is excreted in the urine within 24 hours.
BioavailabilityBioavailability is high after intramuscular injection (approximately 90%) and 100% after intravenous administration.
Onset of ActionThe onset of action is rapid, typically within 2 to 5 minutes after intravenous injection and within 5 to 10 minutes after intramuscular injection.
Peak Plasma TimePeak plasma concentration is reached within 5 to 10 minutes after intramuscular injection and immediately after intravenous injection.
Duration of ActionThe duration of action is approximately 2 to 4 hours.

How It Works

This medicine works by blocking the action of acetylcholine at muscarinic receptors located on smooth muscle cells. Acetylcholine normally stimulates these receptors to cause muscle contraction. By blocking this action, hyoscine butylbromide relaxes the smooth muscles of the gastrointestinal, biliary, and genitourinary tracts, thereby relieving spasms and associated pain. It has a quaternary ammonium structure that limits its passage across the blood-brain barrier, reducing central nervous system side effects compared to other anticholinergics.

Mechanism Steps

1
Binding to muscarinic receptors: Hyoscine butylbromide binds competitively to muscarinic acetylcholine receptors on smooth muscle cells.
2
Inhibition of acetylcholine action: By occupying the receptor, it prevents acetylcholine from binding and triggering muscle contraction.
3
Smooth muscle relaxation: The blockade leads to relaxation of the smooth muscle, relieving spasms and associated pain.
4
Reduced glandular secretions: It also reduces secretions from salivary and other glands, contributing to dry mouth.

💡 How to Take hyozen 20mg injection

Strength: Injection: 20mg per vial

1This medicine is administered by a healthcare professional.
2It is given as an intramuscular or intravenous injection.
3Do not self-administer.
4Follow your doctor's instructions regarding dose and frequency.

Dosage Information

Adult DosageThe usual adult dose is 20mg administered by intramuscular or intravenous injection. For acute spasms, a single dose may be repeated after 30 minutes if needed. The maximum daily dose is 100mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the anticholinergic effects of this medicine. Use with caution and consider dose reduction. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment is provided in the available information. Use with caution in patients with severe renal impairment. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is provided in the available information. Use with caution in patients with severe hepatic impairment. Dose must be individualized by a qualified clinician.
Maximum Daily Dose100mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Alcohol
Avoid
May increase drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 You miss a scheduled dose
→ Contact your healthcare provider for instructions.
💡 Do not self-administer additional doses.

⚠️ Side Effects of hyozen 20mg injection

✅ Common Side Effects

Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Usually resolves on its own.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until it passes. Lie down if needed.
Blurred vision (Common (5-10%))
Avoid activities requiring clear vision. Usually temporary.
Nausea (Common (5-10%))
Take small sips of water. Inform your doctor if persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if severe.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, difficulty breathing, or dizziness.
Urinary retention (Rare (<0.1%))
Seek medical help if you are unable to urinate.
Tachycardia (Rare (<0.1%))
Report palpitations or rapid heartbeat to your doctor immediately.
Acute angle-closure glaucoma (Rare (<0.1%))
Seek emergency care if you experience severe eye pain, headache, or vision changes.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek medical attention if you experience hallucinations.
Confusion
Report to your doctor if you feel confused or disoriented.
Injection site necrosis
Seek medical attention if the injection site becomes painful, swollen, or dark.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tricyclic antidepressants Major
Antihistamines Major
Antipsychotics Major
Beta-blockers Moderate
Digoxin Moderate
Metoclopramide Moderate
Levodopa Minor

🚨 Major Interactions

  • Tricyclic antidepressants (e.g., amitriptyline)
  • Antihistamines (e.g., diphenhydramine)
  • Antipsychotics (e.g., chlorpromazine)

⚡ Moderate Interactions

  • Beta-blockers (e.g., propranolol)
  • Digoxin
  • Metoclopramide

🍷 Alcohol Interaction

Alcohol may increase the sedative and dizzying effects of this medicine. It is advisable to avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to hyoscine butylbromide","Narrow-angle glaucoma","Myasthenia gravis","Severe ulcerative colitis","Tachycardia","Prostatic hypertrophy with urinary retention","Paralytic ileus"]

⚠️ Warnings & Precautions

["Use with caution in elderly patients due to increased risk of anticholinergic effects.","Avoid in patients with autonomic neuropathy.","May cause drowsiness; avoid driving or operating machinery.","Use with caution in patients with liver or kidney disease.","May worsen symptoms of gastroesophageal reflux disease.","Not recommended for children under 6 years."]

🤱 Lactation Safety

Hyoscine butylbromide is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose may cause severe anticholinergic symptoms such as tachycardia, dry mouth, urinary retention, and confusion. Treatment is supportive and symptomatic. Physostigmine may be used as an antidote in severe cases. Seek immediate medical attention.

⏰ Missed Dose

This medicine is usually given as a single dose or as directed by your doctor. If you miss a scheduled dose, contact your healthcare provider for instructions. Do not self-administer additional doses.

Additional Safety Advice

General Safety

This medicine should only be administered by a qualified healthcare professional. Do not attempt to self-administer. Before receiving this medicine, inform your doctor if you have a history of glaucoma, myasthenia gravis, heart problems, liver or kidney disease, or urinary retention. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may cause dizziness or blurred vision, so avoid driving or operating heavy machinery until you know how it affects you. Avoid alcohol while receiving this medicine as it may increase drowsiness. Do not take any other medications without consulting your doctor, as this medicine can interact with many drugs. Keep all follow-up appointments and report any unusual symptoms promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to anticholinergic side effects such as confusion, urinary retention, and dizziness. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to relieve spasms. Inform your surgeon if you have received this medicine recently.

🦷 Dental Procedures

Inform your dentist if you have received this medicine, as it may interact with certain medications used in dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated to reduce dry mouth.
🥗
Avoid alcohol while receiving this medicine.
😴
Get plenty of rest to manage dizziness.
💧
Eat a balanced diet to support overall health.
🧘
Inform your doctor about all medications you are taking.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities requiring alertness until you know how this medicine affects you, as it may cause dizziness or blurred vision.

🥗 Diet Recommendations

Drink plenty of water
Eat high-fiber foods to prevent constipation
Avoid spicy foods that may worsen abdominal discomfort

💼 Impact on Daily Work & Life

This medicine may cause dizziness or blurred vision, which can affect your ability to drive or operate machinery. It is advisable to rest until these effects subside. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

This medicine is usually given as a single dose or short course. Do not stop any prescribed treatment without consulting your doctor. If you experience severe side effects, seek medical attention immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance and increased risk of anticholinergic side effects. Regular monitoring of heart rate, blood pressure, and urinary function is advised. Consult your doctor for alternative treatments if long-term therapy is needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral antispasmodics

Oral medications like hyoscine butylbromide tablets may be used for milder symptoms.

Evidence: Well-established
Heat therapy

Applying a heating pad to the abdomen can help relax muscles and reduce pain.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store below 25°C

❌ DON'T

Do not freeze

✅ DO

Protect from light

❌ DON'T

Do not use if solution is discolored or contains particles

✅ DO

Keep out of reach of children

❌ DON'T

Do not store in bathroom

✈️ Traveling with This Medicine

This medicine is administered by a healthcare professional and is not for self-administration. If you are traveling and need this medicine, carry a copy of your prescription and original packaging. Store it below 25°C, protected from light. Do not freeze. Check customs regulations for carrying injectable medications. It is advisable to carry a doctor&#039;s note explaining the need for this medicine.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 40-year-old man with severe abdominal cramps due to gastroenteritis
He received this medicine as an intramuscular injection in the emergency department. Within 10 minutes, his pain significantly decreased. He experienced mild dry mouth but no other side effects. He was advised to follow up with his doctor.
💡 Lesson: This medicine provides rapid relief from abdominal spasms when administered by a healthcare professional.
👤 A 65-year-old woman with biliary colic
She was given this medicine intravenously for severe right upper abdominal pain. Her pain improved within 5 minutes. She felt dizzy for about an hour but it resolved. She was monitored for any anticholinergic effects.
💡 Lesson: Elderly patients may experience more dizziness and should be monitored closely after administration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 2 to 5 minutes after intravenous injection and within 5 to 10 minutes after intramuscular injection.

Q: How long does the effect last?

A: The effect usually lasts for about 2 to 4 hours.

Q: Can I take this medicine at home?

A: No, this medicine must be administered by a healthcare professional in a clinical setting.

Q: What are the common side effects?

A: Common side effects include dry mouth, dizziness, blurred vision, nausea, and constipation.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine if I have glaucoma?
  • Will this medicine affect my blood pressure?
  • Can I drive after receiving this injection?
  • Is this medicine safe for kidney patients?
  • What if I miss a dose?
  • Can I drink alcohol after this injection?

🔄 Substitutes for hyozen 20mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally.
    Fact: This medicine is an injection and must be administered by a healthcare professional.
  • Myth: This medicine is safe for everyone.
    Fact: It is contraindicated in certain conditions such as glaucoma and myasthenia gravis.

🔄 Alternative Options

Generic Alternatives

  • Hyoscine butylbromide injection

Brand Alternatives

  • Buscopan injection
  • Hyoscine injection

📊 Comparison with Similar Medicines

[{"medicine":"Hyoscine butylbromide","class":"Antispasmodic","route":"Parenteral","onset":"2-5 minutes","duration":"2-4 hours"},{"medicine":"Dicyclomine","class":"Antispasmodic","route":"Parenteral","onset":"5-10 minutes","duration":"4-6 hours"}]

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