Menotrophin 150IU Injection: A Complete Guide to Uses, Dosage, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain (more than 2 kg in 24 hours)
- Difficulty breathing or shortness of breath
- Decreased urine output
- Severe nausea and vomiting
- Chest pain or leg swelling
- Sudden severe headache or visual disturbances
- Signs of allergic reaction such as rash, itching, or swelling of the face
If experiencing severe symptoms, call emergency services immediately.
What is humog 150 hp injection used for?
This medicine is a gonadotropin preparation containing menotrophin, used to treat infertility by stimulating ovulation in women and sperm production in men. It is given by injection under medical supervision.
- Generic Name: Menotrophin (150IU)
- Manufacturer: Bharat Serums & Vaccines Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 humog 150 hp injection के बारे में (Hindi Summary)
उपयोग: यह दवा पुरुषों और महिलाओं दोनों में बांझपन के इलाज के लिए इस्तेमाल की जाती है। महिलाओं में यह अंडाशय को उत्तेजित करके अंडे के उत्पादन और परिपक्वता को बढ़ावा देती है, जिससे ओव्यूलेशन होता है। यह आईवीएफ और अन्य सहायक प्रजनन तकनीकों में भी उपयोग की जाती है। पुरुषों में यह शुक्राणु उत्पादन को बढ़ाने में मदद करती है जब शरीर पर्याप्त गोनाडोट्रोपिन नहीं बना पाता। यह दवा केवल प्रजनन विशेषज्ञ की देखरेख में ही दी जानी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन, पेट में भारीपन, सिरदर्द, थकान और मूड में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम (OHSS) हो सकता है, जिसमें तेजी से वजन बढ़ना, गंभीर पेट दर्द, उल्टी, और सांस लेने में कठिनाई हो सकती है। इसके अलावा, कई गर्भधारण का खतरा भी होता है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य प्रजनन विशेषज्ञ की देखरेख में ही ली जानी चाहिए। बिना प्रशिक्षण के खुद इंजेक्शन न लगाएं। डॉक्टर द्वारा बताई गई खुराक और समय का सख्ती से पालन करें। नियमित अल्ट्रासाउंड और रक्त परीक्षण करवाते रहें। OHSS के लक्षण जैसे गंभीर पेट दर्द, तेजी से वजन बढ़ना, या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से संपर्क करें। इलाज के दौरान शराब और धूम्रपान से बचें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं।
💊 humog 150 hp injection Uses & Benefits
[{"condition":"Ovulation induction in anovulatory infertility","description":"Used to stimulate follicular development and ovulation in women who do not ovulate regularly, such as those with polycystic ovary syndrome (PCOS).","evidence":"Well-established"},{"condition":"Controlled ovarian hyperstimulation for assisted reproductive technologies (ART)","description":"Used to induce multiple follicular development for procedures like in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).","evidence":"Well-established"},{"condition":"Male hypogonadotropic hypogonadism","description":"Used to stimulate spermatogenesis in men with low gonadotropin levels due to pituitary or hypothalamic dysfunction.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Unexplained infertility","description":"Sometimes used in combination with intrauterine insemination (IUI) for unexplained infertility, although evidence is limited.","evidence":"Limited"}]
Primary treatment for: Infertility
Also treats: Polycystic ovary syndrome (PCOS), Hypogonadotropic hypogonadism
📋 Drug Information
| Generic Name(s) | Menotrophin (150IU) |
| Brand Name | humog 150 hp injection |
| Manufacturer | Bharat Serums & Vaccines Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Gonadotropins |
| Route of Administration | Parenteral (intramuscular or subcutaneous injection) |
| Storage | Store the lyophilized powder at room temperature (15-30°C) in a dry place, protected from light. After reconstitution, the solution should be used immediately or stored as directed by the manufacturer. Do not freeze. |
| Shelf Life | Refer to the packaging for the expiry date. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Menotrophin is a gonadotropin preparation that contains follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in a 1:1 ratio. It acts by binding to specific G protein-coupled receptors on the surface of target cells in the gonads. In women, FSH binds to FSH receptors on ovarian granulosa cells, stimulating follicular growth and maturation, while LH binds to LH receptors on theca cells and triggers androgen production, which is then aromatized to estrogen. In men, FSH acts on Sertoli cells to promote spermatogenesis, and LH acts on Leydig cells to stimulate testosterone production. The overall effect is to mimic the natural pituitary gonadotropins, thereby driving gonadal function when endogenous production is insufficient.
Mechanism Steps
💡 How to Take humog 150 hp injection
Strength: Lyophilized powder for injection, 150 IU per vial, with solvent for reconstitution.
Dosage Information
| Adult Dosage | The dose of this medicine is highly individualized and depends on the indication, the patient's response, and the treatment protocol. For ovulation induction, a typical starting dose is 75-150 IU daily, but it may be adjusted based on ultrasound and estradiol levels. For controlled ovarian hyperstimulation in ART, the dose may range from 150-300 IU daily. For male hypogonadotropic hypogonadism, doses of 75-150 IU three times a week may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not intended for use in elderly patients. Safety and efficacy have not been established. |
| Renal Impairment | No specific dose adjustments are established for renal impairment. Use with caution and monitor closely. |
| Hepatic Impairment | No specific dose adjustments are established for hepatic impairment. Use with caution and monitor closely. |
| Maximum Daily Dose | The maximum daily dose is determined by the treating physician based on the patient's response and should not be exceeded. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of humog 150 hp injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| GnRH antagonists | Major | |
| Clomiphene citrate | Moderate |
🚨 Major Interactions
- Gonadotropin-releasing hormone (GnRH) antagonists
⚡ Moderate Interactions
- Clomiphene citrate
🍷 Alcohol Interaction
Alcohol may impair fertility and should be avoided during treatment with this medicine. It can also increase the risk of liver problems and may worsen side effects such as mood swings and fatigue.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to menotrophin or any component of the formulation","Pregnancy","Primary ovarian failure","Uncontrolled thyroid or adrenal dysfunction","Intracranial lesions such as pituitary tumors","Abnormal uterine bleeding of unknown cause","Ovarian cysts or enlargement not due to polycystic ovary syndrome","Hormone-sensitive cancers of the reproductive system"]
⚠️ Warnings & Precautions
["This medicine should only be used by or under the supervision of a physician experienced in fertility treatment.","Ovarian hyperstimulation syndrome (OHSS) is a serious risk. Monitor closely with ultrasound and blood tests.","Multiple pregnancies are a common risk. Discuss with your doctor.","There is an increased risk of thromboembolic events. Use with caution in patients with risk factors.","In men, this medicine may cause fluid retention. Use with caution in patients with heart or kidney disease.","Do not use if the solution is cloudy or contains particles.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether menotrophin is excreted in human breast milk. This medicine is not intended for use during breastfeeding. Consult your doctor before using this medicine if you are breastfeeding.
💊 Overdose Management
Overdose of menotrophin may lead to ovarian hyperstimulation syndrome (OHSS). If you suspect an overdose, contact your doctor immediately. Treatment is symptomatic and supportive, and may include hospitalization for monitoring and management of complications.
⏰ Missed Dose
If you miss a dose, contact your doctor or fertility clinic for advice. Do not double the dose to make up for a missed one. The timing of doses is critical for the success of treatment, so it is important to follow the prescribed schedule closely.
Additional Safety Advice
This medicine must only be administered under the supervision of a qualified fertility specialist. Do not self-administer unless you have been properly trained by a healthcare professional. Follow the exact dosage and timing prescribed by your doctor. Regular monitoring with blood tests and ultrasound is essential to assess your response and to adjust the dose. Report any signs of ovarian hyperstimulation syndrome (OHSS) such as severe pelvic pain, rapid weight gain, or difficulty breathing immediately. Use effective barrier contraception during treatment unless you are trying to conceive, as this medicine increases the chance of multiple pregnancies. Avoid alcohol and smoking while undergoing fertility treatment. Inform your doctor about all other medications, supplements, and herbal products you are taking. Store the powder and solvent as directed on the packaging. Do not use if the solution is cloudy or contains particles. Keep out of reach of children. If you miss a dose, contact your doctor for advice; do not double the dose. Never share this medicine with others.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly patients. Safety and efficacy have not been established.
🤰 Pregnancy Planning (TTC)
This medicine is used to help achieve pregnancy. If you are planning pregnancy, consult your doctor for appropriate evaluation and treatment. Once pregnancy is confirmed, discontinue this medicine.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your doctor before starting this medicine. It may not be suitable immediately after certain surgeries.
🦷 Dental Procedures
No specific precautions are required for dental procedures. However, inform your dentist about all medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid intense or high-impact activities that could cause ovarian torsion, especially if you have enlarged ovaries. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause fatigue, mood swings, or dizziness, which could affect your ability to work or drive. Avoid driving or operating machinery if you feel unwell. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Treatment duration is determined by your response and the treatment protocol. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of menotrophin may increase the risk of ovarian hyperstimulation syndrome (OHSS) and multiple pregnancies. There is no evidence to suggest an increased risk of ovarian cancer, but long-term follow-up is recommended. Regular monitoring with ultrasound and blood tests is essential to assess response and adjust treatment. In men, long-term use may lead to fluid retention or acne. Treatment should be reviewed periodically by a specialist.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Weight loss, diet, and exercise can improve fertility in some cases.
Evidence: Well-establishedAn oral medication for ovulation induction, often used as first-line treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label. Keep a copy of your prescription and a letter from your doctor explaining the medical need. Store the powder at room temperature and protect it from light. If reconstituted, use immediately or store as directed. For air travel, keep it in your carry-on luggage to avoid temperature extremes. Check customs regulations for importing medications. Adjust injection timing if crossing time zones, but consult your doctor first.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It typically takes 5 to 7 days to see an effect, but the full response may take up to 2 weeks or more. Your doctor will monitor your progress with ultrasound and blood tests.
A: Contact your doctor or fertility clinic for advice. Do not double the dose.
A: No, this medicine is not intended for use during pregnancy. If you become pregnant, stop the medicine and inform your doctor immediately.
🤔 Common Patient Concerns
🔄 Substitutes for humog 150 hp injection
View AllAlternative brands with exact same active ingredient:
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eventin 150iu injectionManeesh Pharmaceuticals Ltd ₹500.00 80.3% CHEAPER
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ghm 150iu injectionSun Pharmaceutical Industries Ltd ₹790.00 68.9% CHEAPER
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menovul 150iu injectionWalter Bushnell ₹874.28 65.6% CHEAPER
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ovulate-m 150iu injectionVhb Life Sciences Inc ₹875.00 65.5% CHEAPER
-
grafova 150iu injectionGlenmark Pharmaceuticals Ltd ₹984.38 61.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Menotrophin guarantees pregnancy.
Fact: Menotrophin increases the chance of pregnancy but does not guarantee it. Success rates vary based on individual factors. - Myth: Menotrophin can be used without monitoring.
Fact: Menotrophin requires close monitoring with ultrasound and blood tests to ensure safety and effectiveness.
🔄 Alternative Options
Generic Alternatives
- Menotrophin 150 IU injection
Brand Alternatives
- Eema HMG 150IU Injection