hepacure 100mg/150mg tablet - Pancreatin (100mg) + Ornithine (150mg) medicine

Livogard Tablet: Complete Medicine Guide

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🏭 Mission Research Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for pancreatin in pancreatic insufficiency; limited for ornithine in liver support.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe abdominal pain that does not go away
  • Blood in stool or vomit
  • Persistent vomiting
  • Yellowing of the skin or eyes
  • Decreased urine output
  • Severe allergic rash or hives

If experiencing severe symptoms, call emergency services immediately.

What is hepacure 100mg/150mg tablet used for?

This medicine is a combination of Pancreatin 100 mg and Ornithine 150 mg used to support digestion and liver function. It is taken orally with meals, usually two to three times a day, as prescribed by a doctor.

  • Generic Name: Pancreatin (100mg) + Ornithine (150mg)
  • Manufacturer: Mission Research Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 hepacure 100mg/150mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैंक्रियाटिन और ऑर्निथिन का संयोजन है। यह पाचन में मदद करती है और लिवर को अमोनिया से छुटकारा दिलाने में सहायक हो सकती है। इसका उपयोग अग्नाशय की कमजोरी, पाचन संबंधी विकार और कुछ लिवर की समस्याओं में किया जाता है। इसे डॉक्टर की सलाह से ही लें।

साइड इफेक्ट्स: आमतौर पर यह दवा सहन की जाती है, लेकिन कुछ लोगों को मतली, पेट में हल्की तकलीफ, गैस, दस्त या कब्ज हो सकती है। कभी-कभी एलर्जी, त्वचा पर चकत्ते या सूजन भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं। अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या तेज पेट दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार भोजन के साथ लें। गोली को पानी के साथ निगलें, चबाएं नहीं। शराब न लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को ठंडी, सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें। बिना डॉक्टर की सलाह के दवा बंद न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 hepacure 100mg/150mg tablet Uses & Benefits

[{"condition":"Exocrine pancreatic insufficiency","description":"This medicine provides pancreatic enzymes to help digest food when the pancreas does not produce enough enzymes, as in chronic pancreatitis or after pancreatic surgery.","evidence":"Well-established for pancreatin component"},{"condition":"Malabsorption syndromes","description":"Used as an adjunct to improve absorption of fats, proteins, and carbohydrates in people with poor digestion.","evidence":"Well-established for pancreatin component"},{"condition":"Chronic liver disease support","description":"Ornithine may help lower blood ammonia levels and support liver function in some chronic liver conditions.","evidence":"Limited to moderate"},{"condition":"Post-pancreatic surgery recovery","description":"Enzyme replacement may be prescribed after pancreatic resection to aid digestion.","evidence":"Well-established for pancreatin component"}]

Off-label uses: [{"condition":"General digestive discomfort","description":"Sometimes used off-label for bloating and indigestion, but evidence is limited.","evidence":"Limited"},{"condition":"Hepatic encephalopathy adjunct","description":"Ornithine has been studied off-label to help manage ammonia levels in liver disease, but it is not a first-line treatment.","evidence":"Limited"}]

Primary treatment for: Exocrine pancreatic insufficiency

Also treats: Chronic pancreatitis, Malabsorption syndrome, Chronic liver disease

📋 Drug Information

Generic Name(s)Pancreatin (100mg) + Ornithine (150mg)
Brand Namehepacure 100mg/150mg tablet
ManufacturerMission Research Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture, or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to help the enzymes mix with food and improve digestion.
2
Swallow the tablet whole with water; do not crush or chew it unless your doctor advises otherwise.
3
Avoid alcohol completely, as it can worsen pancreatitis and liver disease.
4
Keep all follow-up appointments so your doctor can monitor your response and adjust the dose if needed.
5
Tell your doctor about all other medicines, especially antacids, acarbose, and iron supplements.
6
If you experience severe abdominal pain, vomiting, or signs of allergy, stop the medicine and seek medical help immediately.
7
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Bloating and indigestion after meals
This medicine is commonly prescribed for digestive enzyme support.
Likely Use
✅
Fatty stools
Pancreatin helps digest fats and may reduce steatorrhea.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPancreatic enzymes are proteins and are not absorbed intact; they act locally in the gut. Ornithine is absorbed from the small intestine by active transport.
DistributionOrnithine distributes into body fluids and tissues, including the liver. Pancreatin enzymes remain in the gastrointestinal tract and are not distributed systemically.
Protein BindingNot established from the available information for pancreatin. Ornithine binding to plasma proteins is not well characterized.
MetabolismPancreatin enzymes are broken down by digestive processes and intestinal proteases. Ornithine is metabolized in the liver through the urea cycle and other pathways.
Half-LifeNot established from the available information.
ExcretionPancreatin enzymes are excreted in feces as inactive fragments. Ornithine metabolites, including urea, are excreted mainly in urine.
BioavailabilityNot established from the available information for pancreatin because it acts locally. Ornithine bioavailability from oral doses is not well defined.
Onset of ActionDigestive enzyme effects begin within 30 to 60 minutes after taking the tablet with food. Ornithine effects on ammonia may take longer and depend on the dose and liver function.
Peak Plasma TimeNot established from the available information.
Duration of ActionEnzyme activity lasts as long as food remains in the small intestine, typically 1 to 2 hours. Ornithine's effect on ammonia may last several hours.

How It Works

Pancreatin delivers amylase, lipase, and protease enzymes into the small intestine, where they break down starches into sugars, fats into fatty acids and glycerol, and proteins into peptides and amino acids. This improves digestion and absorption of nutrients. Ornithine is an amino acid that enters the urea cycle and helps convert toxic ammonia into urea, which the kidneys can excrete. By supporting both digestion and ammonia detoxification, this combination may help people with pancreatic and liver-related digestive problems.

Mechanism Steps

1
Enzyme release in the intestine: After swallowing, the tablet disintegrates in the stomach and releases pancreatin enzymes into the small intestine.
2
Breakdown of nutrients: Lipase breaks down fats, amylase breaks down carbohydrates, and protease breaks down proteins into smaller absorbable units.
3
Improved absorption: The smaller nutrient molecules are absorbed through the intestinal wall into the bloodstream.
4
Ornithine enters urea cycle: Ornithine is absorbed and transported to the liver, where it participates in the urea cycle to convert ammonia into urea.
5
Ammonia detoxification: The urea produced is excreted by the kidneys, helping to lower blood ammonia levels.

💡 How to Take hepacure 100mg/150mg tablet

Strength: Tablet containing Pancreatin 100 mg and Ornithine 150 mg.

1Take the tablet with a meal and a full glass of water.
2Swallow the tablet whole; do not crush or chew unless advised.
3If you have trouble swallowing, ask your doctor for alternative forms.
4Follow the prescribed schedule consistently.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken two to three times a day with meals, or as directed by your doctor. The exact dose depends on the condition being treated, your age, weight, kidney and liver function, and how well you respond. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageOlder adults may be more sensitive to side effects. The dose should be individualized by a clinician, taking into account kidney and liver function and other medicines.
Renal ImpairmentUse with caution in kidney disease. Dose adjustment may be needed based on kidney function. Consult your doctor.
Hepatic ImpairmentUse with caution in liver disease. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with food
Helps enzymes mix with food for better digestion.
Alcohol
Avoid
Can worsen pancreatitis and liver disease.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of hepacure 100mg/150mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food and water. If nausea persists, consult your doctor.
Abdominal discomfort or bloating (Common (5-10%))
Try taking the tablet with a smaller meal. If it continues, talk to your doctor.
Diarrhea or constipation (Uncommon (1-5%))
Stay hydrated. If it lasts more than a few days, consult your doctor.
Change in stool odor (Uncommon (1-5%))
This is usually harmless and related to enzyme activity. No action needed unless bothersome.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you have difficulty breathing, swelling of face or throat, or widespread rash.
Severe abdominal pain or vomiting (Rare (<0.1%))
Stop the medicine and contact your doctor right away.
Blood in stool or vomit (Rare (<0.1%))
Seek immediate medical attention.

⚠️ Rare Side Effects

Hyperuricemia (high uric acid)
Report to your doctor if you have joint pain or swelling.
Mouth irritation or soreness
Rinse mouth after taking the tablet. Consult doctor if it persists.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Acarbose Major
Antacids Major
Omeprazole Moderate
Iron supplements Moderate
Folic acid Minor

🚨 Major Interactions

  • Acarbose
  • Antacids containing calcium carbonate or magnesium hydroxide

⚡ Moderate Interactions

  • Proton pump inhibitors (e.g., omeprazole)
  • Iron supplements

🍷 Alcohol Interaction

Alcohol can worsen the underlying pancreatic or liver condition and may reduce the benefit of this medicine. It is best to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to pancreatin or porcine-derived products","Acute pancreatitis","Acute exacerbation of chronic pancreatitis","Bowel obstruction","Severe acute liver disease without medical supervision"]

⚠️ Warnings & Precautions

["Do not use without a doctor's advice if you have a history of pancreatitis.","Use with caution in kidney disease.","Use with caution in liver disease; dose adjustment may be needed.","Avoid alcohol while taking this medicine.","Do not exceed the prescribed dose.","Keep out of reach of children.","Inform your doctor if you are pregnant or breastfeeding.","Tell your doctor about all other medicines you take."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely to cause serious harm, but it may cause stomach upset, nausea, or diarrhea. If you suspect a large overdose, contact your doctor or a poison control center immediately. Do not try to vomit unless instructed by a medical professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember if it is still close to the scheduled time. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, usually with meals to help the enzymes mix with food. Swallow the tablet whole with a glass of water unless your doctor advises otherwise. Do not crush or chew the tablet unless specifically instructed. Keep all follow-up appointments so your doctor can check how well the medicine is working and adjust the dose if needed. Tell your doctor about all other medicines, supplements, and herbal products you take, because some can interfere with digestive enzymes or ornithine. Avoid alcohol, as it can worsen pancreatitis and liver problems. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Store the tablets in a cool, dry place away from direct sunlight and out of reach of children. Never share this medicine with anyone else, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults may be more sensitive to side effects. Dose should be individualized based on kidney and liver function and other medicines.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy or if you become pregnant while taking this medicine.

🏥 Post-Surgery Considerations

If you have had pancreatic or liver surgery, this medicine may be prescribed as part of your recovery. Follow your surgeon's instructions.

🦷 Dental Procedures

No specific precautions are established. Inform your dentist about all medicines you take.

💚 Lifestyle Tips for Better Results

🏃
Eat small, frequent meals to reduce digestive burden.
🥗
Avoid alcohol and smoking.
😴
Stay hydrated throughout the day.
💧
Follow a low-fat diet if you have pancreatitis.
🧘
Maintain a healthy weight.
🌞
Get regular exercise as advised by your doctor.

🏋️ Exercise Considerations

Moderate exercise is usually safe. If you have pancreatitis or liver disease, avoid strenuous activity during flare-ups and follow your doctor's advice.

🥗 Diet Recommendations

Include easily digestible foods.
Reduce fried and fatty foods.
Eat plenty of fruits and vegetables.
Stay well hydrated.
Avoid alcohol.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you feel dizzy or unwell, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or allergic reactions, stop immediately and seek medical help.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well tolerated when taken as prescribed. Regular monitoring of digestive symptoms, nutritional status, and liver function may be needed. Do not stop or continue long-term use without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

A low-fat diet and small frequent meals can help manage digestive symptoms.

Evidence: Well-established
Enzyme replacement therapy alone

Pancreatin alone may be sufficient for some people.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Follow your doctor's advice for routine vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are traveling across time zones, continue taking it with meals as usual. Check customs regulations for carrying prescription medicines. Keep enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with chronic pancreatitis
He was prescribed this medicine to help with digestion and fatty stools. After taking it regularly with meals for a month, he noticed less bloating and better stool consistency. He also avoided alcohol and followed a low-fat diet.
💡 Lesson: Taking the medicine with meals and making lifestyle changes improves digestive symptoms.
👤 A 60-year-old woman with liver cirrhosis
She was given this medicine as part of her liver support. Her doctor monitored her ammonia levels and adjusted the dose. She reported feeling less fatigued and had fewer episodes of confusion.
💡 Lesson: Regular monitoring and doctor follow-up are important when using this medicine for liver support.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Digestive enzyme effects begin within 30 to 60 minutes after taking with food. Ornithine's effect on ammonia may take longer.

Q: Can I take it without food?

A: It is best taken with meals to help the enzymes mix with food. Follow your doctor's instructions.

Q: Is it safe during pregnancy?

A: Consult your doctor before use during pregnancy or breastfeeding.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for hepacure 100mg/150mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure pancreatitis.
    Fact: This medicine helps manage symptoms but does not cure pancreatitis. Lifestyle changes and medical treatment are essential.
  • Myth: It is safe to take without a prescription.
    Fact: This medicine should be taken only under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Pancreatin + Ornithine combination tablets from other manufacturers

Brand Alternatives

  • Livogard Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Pancreatin alone","difference":"Does not contain ornithine; used only for enzyme replacement."},{"medicine":"Ornithine alone","difference":"Does not contain pancreatin; used mainly for ammonia detoxification."}]

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