hakof-br expectorant - Bromhexine (4mg/5ml) + Guaifenesin (100mg/5ml) medicine

Axom-BR Oral Suspension: Complete Medicine Guide

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🏭 Morstella Biotech 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for symptomatic relief of productive cough.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Swelling of the face, lips, tongue, or throat
  • Severe rash or blistering of the skin
  • Blood in vomit or black, tarry stools
  • Severe abdominal pain
  • Persistent fever or cough lasting more than a week
  • Yellowing of the skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is hakof-br expectorant used for?

This medicine is a combination of bromhexine and guaifenesin used to treat productive cough by thinning mucus and making it easier to cough out. It is available as an oral suspension and should be taken as directed by a doctor.

  • Generic Name: Bromhexine (4mg/5ml) + Guaifenesin (100mg/5ml)
  • Manufacturer: Morstella Biotech
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 hakof-br expectorant के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और गुआइफेनेसिन का संयोजन है, जिसका उपयोग कफ और छाती में जमे बलगम को पतला करके बाहर निकालने में मदद करने के लिए किया जाता है। यह मुख्य रूप से उत्पादक खांसी (जिसमें बलगम आता है) के इलाज में उपयोग की जाती है। यह दवा बलगम को पतला करती है और उसे खांसकर बाहर निकालना आसान बनाती है। यह तीव्र या दीर्घकालिक ब्रोंकाइटिस जैसी स्थितियों में राहत देने के लिए दी जाती है। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हो सकते हैं। कुछ लोगों को एलर्जी जैसे दाने, खुजली या चेहरे, होंठ या जीभ में सूजन भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, गंभीर दाने या त्वचा संबंधी समस्या हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को गर्भावस्था, स्तनपान, यकृत या गुर्दे की बीमारी, पेट के अल्सर या अस्थमा के बारे में बताएं। यह दवा चक्कर या नींद ला सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। बिना डॉक्टर की सलाह के इस दवा को लंबे समय तक न लें। यदि खांसी 7 दिनों से अधिक रहती है, बुखार, दाने या लगातार सिरदर्द हो तो डॉक्टर से मिलें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 hakof-br expectorant Uses & Benefits

[{"condition":"Productive cough (acute bronchitis)","description":"Helps loosen and thin mucus in the airways, making it easier to cough out and providing symptomatic relief.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used as an adjunct to help manage thick secretions in chronic bronchitis, though it does not treat the underlying disease.","evidence":"Moderate"},{"condition":"Respiratory conditions with thick mucus","description":"May be used in other conditions where thick mucus is a problem, such as COPD, but only under medical supervision.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Productive cough

Also treats: Acute bronchitis, Chronic bronchitis, COPD

📋 Drug Information

Generic Name(s)Bromhexine (4mg/5ml) + Guaifenesin (100mg/5ml)
Brand Namehakof-br expectorant
ManufacturerMorstella Biotech
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. Keep the bottle tightly closed.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Shake the bottle well before each dose to ensure proper mixing of the suspension.
2
Use a proper measuring device to avoid inaccurate dosing.
3
Take this medicine with food if it causes stomach upset.
4
Stay well hydrated to help thin mucus and soothe the throat.
5
Do not use this medicine for more than 7 days without consulting a doctor.
6
Avoid taking other cough suppressants unless advised by your doctor.
7
If you have a history of ulcers, inform your doctor before taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismBromhexine is metabolized in the liver to active metabolites, including ambroxol. Guaifenesin is also metabolized in the liver. The exact metabolic pathways are not fully established from the available information.
Half-LifeNot established from the available information.
ExcretionBoth bromhexine and its metabolites, as well as guaifenesin metabolites, are primarily excreted in the urine. The exact proportions are not established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine combines two agents with complementary actions. Bromhexine is a mucolytic that reduces the viscosity of mucus by breaking down acidic mucopolysaccharide fibers, thereby thinning secretions. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of bronchial secretions by increasing hydration, which helps cilia to move mucus more effectively. Together, they enhance the clearance of mucus from the respiratory tract, providing symptomatic relief from productive cough.

Mechanism Steps

1
Bromhexine breaks down mucus structure: Bromhexine disrupts the network of acidic mucopolysaccharide fibers in mucus, reducing its thickness and stickiness.
2
Guaifenesin increases mucus hydration: Guaifenesin draws water into the mucus, further thinning it and increasing its volume, which makes it easier to expel.
3
Enhanced mucociliary clearance: The combined effect allows the cilia in the airways to move the thinned mucus more effectively towards the throat, where it can be coughed out.

💡 How to Take hakof-br expectorant

Strength: Each 5 ml of oral suspension contains Bromhexine 4 mg and Guaifenesin 100 mg.

1Shake the bottle well before each use to ensure the medicine is evenly mixed.
2Use a measuring cup or spoon provided with the medicine to measure the correct dose.
3Take the medicine orally, with or without food. Taking it with food may reduce stomach upset.
4Swallow the suspension; do not chew or crush.
5Wash the measuring cup after each use and close the bottle tightly.
6Follow the dosage schedule prescribed by your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 ml (providing 4-8 mg bromhexine and 100-200 mg guaifenesin) taken three to four times daily, depending on the severity of the condition. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Follow your doctor's instructions carefully.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor for appropriate dosing.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor for appropriate dosing.
Maximum Daily DoseNot established from the available information. Do not exceed the dose prescribed by your doctor.

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Water
Drink plenty of fluids
Helps thin mucus and soothe the throat.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of hakof-br expectorant

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce stomach upset. If nausea persists, consult your doctor.
Vomiting (Common (1-10%))
Stay hydrated with small sips of water. If vomiting is severe or persistent, seek medical advice.
Diarrhea (Common (1-10%))
Drink plenty of fluids to prevent dehydration. Consult a doctor if diarrhea lasts more than 2 days.
Stomach pain (Common (1-10%))
Take with food. If pain is severe or persistent, contact your doctor.
Headache (Common (1-10%))
Rest and stay hydrated. If headache is severe or unusual, consult a doctor.
Dizziness (Uncommon (0.1-1%))
Avoid driving or operating machinery until you feel normal. If dizziness persists, consult your doctor.
Drowsiness (Uncommon (0.1-1%))
Avoid activities requiring alertness. If drowsiness is excessive, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.
Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools, vomit blood, or have severe abdominal pain.

⚠️ Rare Side Effects

Hypersensitivity reactions
Discontinue and seek medical advice if you experience rash, itching, or swelling.
Bronchospasm
Seek immediate medical attention if you experience wheezing or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Codeine Major
Warfarin Moderate
Amoxicillin Moderate
Erythromycin Moderate
Diuretics Minor

🚨 Major Interactions

  • Antitussives (e.g., codeine)

⚡ Moderate Interactions

  • Antibiotics (e.g., amoxicillin, erythromycin)
  • Warfarin

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and gastrointestinal upset. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to bromhexine, guaifenesin, or any component of the formulation.","Children under the age of 2 years (unless directed by a physician).","Active peptic ulcer disease."]

⚠️ Warnings & Precautions

["Do not use for a chronic cough or a cough with excessive secretions without medical advice.","Use with caution in patients with a history of gastric ulcers.","Use with caution in patients with severe liver or kidney impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","If symptoms persist for more than 7 days, worsen, or are accompanied by fever, rash, or persistent headache, consult a doctor.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal pain. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also, disclose any medical conditions you have, especially liver or kidney disease, stomach ulcers, or asthma. This medicine may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Do not take this medicine for longer than the recommended duration without consulting a doctor. If your cough persists for more than a week, recurs, or is accompanied by fever, rash, or persistent headache, stop use and seek medical advice. Keep this medicine out of reach of children. Do not use it to treat a chronic cough or a cough with excessive secretions without medical supervision. Always follow the dosage instructions provided by your healthcare provider.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects such as dizziness, drowsiness, and gastrointestinal upset. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety profile during pregnancy is not well established.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, consult your doctor before taking this medicine, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It is generally safe, but your dentist should be aware of all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of fluids.
🥗
Use a humidifier to add moisture to the air, which can help loosen mucus.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body recover.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid irritants like strong perfumes or pollutants.

🏋️ Exercise Considerations

This medicine may cause dizziness or drowsiness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light activity like walking is generally safe.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup to soothe the throat.
Include foods rich in vitamin C to support immune function.
Avoid dairy products if they seem to thicken mucus.
Eat a balanced diet to support overall health.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Otherwise, it should not significantly impact your daily work life.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to gastrointestinal disturbances or other side effects. It is intended for short-term symptomatic relief. If your symptoms persist, consult a doctor to determine the underlying cause.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal irrigation

Rinsing nasal passages with saline can help clear mucus.

Evidence: Moderate
Honey

A spoonful of honey can soothe the throat and reduce cough.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccination, inform your healthcare provider that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from direct sunlight. If you are crossing time zones, continue taking the medicine at the intervals prescribed by your doctor, but adjust the timing gradually to the new local time. Keep it in your carry-on luggage to avoid extreme temperatures in checked baggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough with thick mucus. After taking it as directed for 5 days, he noticed that his cough became more productive and his chest felt less congested. He experienced mild nausea initially, which subsided when he took the medicine with food.
💡 Lesson: Taking this medicine with food can reduce stomach upset, and it effectively helps clear mucus in acute bronchitis.
👤 A 60-year-old woman with chronic bronchitis
She used this medicine as part of her management for chronic bronchitis. She found that it helped loosen her chest congestion, making it easier to breathe. However, she was advised not to use it for extended periods without medical supervision.
💡 Lesson: This medicine can provide symptomatic relief in chronic bronchitis, but it should be used under medical supervision and not as a long-term solution.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts to provide relief within a few hours, but the full effect may take a day or two. It works by thinning mucus, making it easier to cough out.

Q: Can I take this medicine with antibiotics?

A: Yes, but inform your doctor. Bromhexine may increase the concentration of certain antibiotics in the lungs, which can be beneficial, but it should be under medical supervision.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing and safety.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Can I take this medicine during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy. The safety profile is not well established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for hakof-br expectorant

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for productive cough with thick mucus. It is not effective for dry cough or cough due to other causes.
  • Myth: It is safe to take this medicine for a long time.
    Fact: This medicine is for short-term use. Prolonged use should only be under medical supervision.
  • Myth: You can take this medicine without a prescription.
    Fact: This medicine should be taken only when prescribed by a doctor.

📊 Comparison with Similar Medicines

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