h2piles rectal cream - Lidocaine (3% w/w) + Calcium Dobesilate (0.25% w/w) medicine

Hemolit Cream: Complete Medicine Guide

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🏭 Hilbert Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
🤰 Pregnancy Category Not established from the available information. Lidocaine is generally considered safe for topical use during pregnancy when used in small amounts, but calcium dobesilate should be used with caution. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for venous insufficiency; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat.
  • Difficulty breathing or wheezing.
  • Irregular heartbeat or palpitations.
  • Severe dizziness or fainting.
  • Signs of systemic toxicity such as confusion, tremors, or seizures.
  • Severe skin rash, blistering, or peeling.
  • No improvement or worsening of symptoms after 7 days of use.

If experiencing severe symptoms, call emergency services immediately.

What is h2piles rectal cream used for?

This medicine is a topical cream containing lidocaine 3% w/w and calcium dobesilate 0.25% w/w. It is used to relieve pain, swelling, and heaviness associated with superficial venous disorders and localized inflammation. Apply a thin layer to the affected area 2-3 times daily or as directed by a doctor.

  • Generic Name: Lidocaine (3% w/w) + Calcium Dobesilate (0.25% w/w)
  • Manufacturer: Hilbert Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 h2piles rectal cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें लिडोकेन 3% w/w और कैल्शियम डोबेसिलेट 0.25% w/w शामिल हैं। इसका उपयोग नसों की समस्या से होने वाले दर्द, सूजन और भारीपन को कम करने के लिए किया जाता है। यह मामूली चोट, कीड़े के काटने और त्वचा की सूजन में भी राहत देती है। यह दवा प्रभावित क्षेत्र पर पतली परत में लगाई जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर लालिमा, खुजली, जलन या सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी एलर्जी की प्रतिक्रिया हो सकती है जैसे दाने या सूजन। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि सांस लेने में कठिनाई, चक्कर आना या दिल की धड़कन अनियमित हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को केवल त्वचा पर लगाएं। आंखों, मुंह और खुले घावों के संपर्क में न आने दें। लगाने से पहले और बाद में हाथ धोएं। डॉक्टर की सलाह के बिना इसे अधिक मात्रा में या लंबे समय तक न लगाएं। अगर लक्षण 7 दिनों में ठीक न हों तो डॉक्टर से परामर्श करें। गर्भवती और स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 h2piles rectal cream Uses & Benefits

[{"condition":"Superficial venous insufficiency","description":"Relieves pain, heaviness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling in the legs associated with poor venous circulation.","evidence":"Moderate"},{"condition":"Localized pain and inflammation","description":"Provides temporary relief from pain and swelling due to minor injuries, sprains, or insect bites.","evidence":"Moderate"},{"condition":"Hemorrhoids","description":"May be used to reduce pain and swelling of external hemorrhoids, though evidence is limited.","evidence":"Limited"},{"condition":"Diabetic microangiopathy","description":"Calcium dobesilate component may help improve microcirculation, but topical use for this indication is not well established.","evidence":"Limited"}]

Off-label uses: [{"condition":"Post-surgical bruising","description":"Sometimes applied to reduce bruising and swelling after minor surgical procedures.","evidence":"Limited"},{"condition":"Chronic venous ulcers","description":"May be used as an adjunct to standard wound care, but should not be applied directly to open ulcers without medical supervision.","evidence":"Limited"}]

Primary treatment for: Superficial venous insufficiency

Also treats: Localized pain and inflammation, Hemorrhoids, Diabetic microangiopathy

📋 Drug Information

Generic Name(s)Lidocaine (3% w/w) + Calcium Dobesilate (0.25% w/w)
Brand Nameh2piles rectal cream
ManufacturerHilbert Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationTopical
StorageStore at room temperature between 15°C and 30°C. Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine only to intact skin and avoid open wounds.
2
Wash your hands before and after application to prevent accidental contact with eyes.
3
Do not use occlusive dressings unless specifically instructed by your doctor.
4
If you experience persistent irritation, stop use and consult a dermatologist.
5
Limit alcohol intake as it can worsen venous insufficiency.
6
Elevate your legs while resting to enhance the effect of the cream.
7
Use the cream consistently for the best results, but do not exceed the recommended frequency.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Leg pain and swelling
This medicine is commonly prescribed for venous insufficiency.
Likely Use
❌
Minor cuts or scrapes
Do not apply to open wounds; consult a doctor for proper wound care.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLidocaine is absorbed through intact skin, but the rate and extent depend on the application area, skin condition, and duration of contact. Systemic absorption is generally low with normal topical use. Calcium dobesilate absorption through intact skin is minimal; it is primarily effective locally. Not established from the available information for specific absorption percentages.
DistributionAfter absorption, lidocaine is distributed throughout the body, with higher concentrations in well-perfused organs such as the liver, lungs, and heart. It crosses the placenta and blood-brain barrier. Calcium dobesilate distribution is not well characterized for topical application. Not established from the available information.
Protein BindingLidocaine is approximately 60-80% bound to plasma proteins, primarily alpha-1-acid glycoprotein and albumin. Calcium dobesilate protein binding is not established from the available information.
MetabolismLidocaine is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4 and CYP1A2, into active and inactive metabolites. Calcium dobesilate is minimally metabolized; it is largely excreted unchanged. Not established from the available information for topical calcium dobesilate metabolism.
Half-LifeThe elimination half-life of lidocaine is approximately 1.5 to 2 hours. The half-life of calcium dobesilate is not established from the available information for topical use.
ExcretionLidocaine metabolites are excreted primarily in the urine, with less than 10% excreted unchanged. Calcium dobesilate is excreted mainly unchanged in the urine and feces. Not established from the available information for topical application.
BioavailabilityThe systemic bioavailability of lidocaine following topical application is variable and depends on the site and condition of the skin. For calcium dobesilate, systemic bioavailability after topical application is considered negligible. Not established from the available information.
Onset of ActionThe numbing effect of lidocaine typically begins within 5 to 10 minutes after application. The venoactive effects of calcium dobesilate may take longer to manifest, often requiring regular use over several days.
Peak Plasma TimePeak plasma concentration of lidocaine after topical application is not well defined and varies with application site. Not established from the available information for calcium dobesilate.
Duration of ActionThe local anesthetic effect of lidocaine lasts approximately 1 to 2 hours after application. The effects of calcium dobesilate on swelling and microcirculation may persist with continued use.

How It Works

This medicine combines a local anesthetic and a venoactive agent. Lidocaine works by blocking voltage-gated sodium channels in nerve cell membranes, which prevents the generation and conduction of nerve impulses, thereby producing local numbness and pain relief. Calcium dobesilate is a synthetic venoactive compound that reduces capillary permeability, inhibits platelet aggregation, and improves erythrocyte flexibility, leading to better microcirculation and reduced edema. Together, they provide symptomatic relief from pain and swelling when applied topically.

Mechanism Steps

1
Sodium channel blockade by lidocaine: Lidocaine binds to the intracellular side of voltage-gated sodium channels in nerve membranes, blocking sodium influx and preventing depolarization.
2
Inhibition of nerve impulse conduction: This blockade stops the propagation of action potentials, leading to reversible loss of sensation in the applied area.
3
Capillary stabilization by calcium dobesilate: Calcium dobesilate reduces the permeability of capillary walls by affecting endothelial cell function and the basement membrane.
4
Reduction of edema and inflammation: By decreasing capillary leakage and improving lymphatic drainage, calcium dobesilate reduces swelling and associated pain.
5
Improved microcirculation: Calcium dobesilate enhances red blood cell flexibility and reduces blood viscosity, promoting better flow through small vessels.

💡 How to Take h2piles rectal cream

Strength: Cream containing lidocaine 3% w/w and calcium dobesilate 0.25% w/w.

1Wash your hands thoroughly before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin layer of the cream to the affected area.
4Gently massage the cream into the skin until it is absorbed.
5Do not cover the area with a bandage unless instructed by your doctor.
6Avoid contact with eyes, mouth, and other mucous membranes.
7Use the cream only as often as prescribed by your doctor.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area 2 to 3 times daily, or as directed by your doctor. Gently massage until absorbed. The dose and frequency may vary depending on the condition being treated. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of lidocaine. Use with caution and follow the doctor's instructions. No specific dose adjustment is established for topical use, but individualization is recommended.
Renal ImpairmentNo specific dose adjustment is established for topical use. However, in patients with severe renal impairment, systemic absorption of lidocaine metabolites may be prolonged. Use with caution and consult a doctor.
Hepatic ImpairmentNo specific dose adjustment is established for topical use. In patients with severe hepatic impairment, lidocaine clearance may be reduced. Use with caution and consult a doctor.
Maximum Daily DoseThe maximum daily dose for topical application is not established from the available information. Do not exceed the frequency recommended by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing required for topical use.
This medicine is applied externally and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of h2piles rectal cream

✅ Common Side Effects

Application site redness (Common (1-10%))
Usually resolves on its own. If it persists or worsens, consult a doctor.
Application site itching (Common (1-10%))
Avoid scratching. Discontinue use if severe and consult a doctor.
Burning sensation (Common (1-10%))
This is often temporary. If it continues, stop use and seek advice.
Dryness or peeling (Uncommon (0.1-1%))
Apply a moisturizer if needed. Consult a doctor if it persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or widespread rash.
Systemic lidocaine toxicity (Rare (<0.1%))
Symptoms include dizziness, confusion, blurred vision, tremors, or irregular heartbeat. Stop use and get emergency help.
Severe skin reactions (e.g., contact dermatitis) (Rare (<0.1%))
Discontinue use and consult a dermatologist if you develop severe rash, blistering, or skin peeling.

⚠️ Rare Side Effects

Methemoglobinemia
Symptoms include bluish skin, headache, shortness of breath. Seek emergency care.
Cardiac arrhythmias
Report palpitations or irregular heartbeat to a doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Class I antiarrhythmics Major
Cimetidine Major
Beta-blockers Moderate
Other local anesthetics Moderate
Topical corticosteroids Minor

🚨 Major Interactions

  • Class I antiarrhythmics (e.g., tocainide, mexiletine)
  • Cimetidine

⚡ Moderate Interactions

  • Beta-blockers (e.g., propranolol)
  • Other local anesthetics

🍷 Alcohol Interaction

No specific interaction between alcohol and topically applied lidocaine or calcium dobesilate has been established. However, alcohol consumption may worsen underlying conditions such as venous insufficiency. It is advisable to limit alcohol intake while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to lidocaine, calcium dobesilate, or any component of the cream.","Application to large areas of broken or infected skin.","Use in children under 12 years without medical advice.","Ophthalmic, oral, or internal use."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes and mucous membranes.","Do not apply to open wounds or areas of infection.","Do not use with occlusive dressings unless directed by a doctor.","Avoid prolonged use over large areas without medical supervision.","Consult a doctor if symptoms persist or worsen after 7 days of use.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid concurrent use of other topical products on the same area without medical advice."]

🤱 Lactation Safety

It is not known whether lidocaine or calcium dobesilate passes into breast milk after topical application. To minimize infant exposure, avoid applying the cream to the breast area. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose from topical application is unlikely if used as directed. If excessive amounts are applied or ingested, seek immediate medical attention. Symptoms of lidocaine toxicity include dizziness, confusion, seizures, and cardiac arrhythmias. Treatment is supportive and symptomatic. In case of accidental ingestion, contact a poison control center or emergency services immediately.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to intact skin and avoid contact with eyes, mucous membranes, and open wounds. Wash your hands thoroughly before and after application unless the hands are the treated area. Do not cover the treated area with airtight dressings unless instructed by a doctor, as this can increase absorption. Avoid using heating pads or warm compresses over the cream. Do not exceed the recommended frequency or duration of use. If your symptoms worsen or do not improve after a few days, consult a healthcare professional. Keep this medicine away from children and pets. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine if you have a history of allergic reactions to lidocaine or calcium dobesilate. Avoid concurrent use of other topical products on the same area without medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of lidocaine. Use with caution and follow your doctor's instructions. Monitor for any signs of skin irritation or systemic effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical lidocaine is generally considered safe in small amounts, but calcium dobesilate should be used with caution. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

After surgery, do not apply this medicine to surgical wounds unless specifically instructed by your surgeon. It may be used on intact skin around the surgical area for pain relief, but always follow your surgeon's advice.

🦷 Dental Procedures

This medicine is for topical skin use and is not intended for oral or dental procedures. For dental pain, consult a dentist for appropriate treatment.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce pressure on leg veins.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Avoid standing or sitting for long periods; take breaks to move around.
💧
Elevate your legs above heart level when resting.
🧘
Wear compression stockings if advised by your doctor.
🌞
Stay hydrated and eat a balanced diet rich in fiber.

🏋️ Exercise Considerations

Exercise is generally safe while using this medicine. However, if you have venous insufficiency, avoid high-impact activities that may worsen symptoms. Listen to your body and consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include foods rich in vitamin C and bioflavonoids, such as citrus fruits and berries.
Reduce sodium intake to minimize fluid retention.
Eat high-fiber foods to prevent constipation, which can worsen hemorrhoids.
Stay well hydrated to support circulation.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to work or drive. However, if you experience dizziness or drowsiness (rare), avoid driving or operating heavy machinery until you feel alert.

🛑 When to Stop This Medicine

Stop using this medicine and consult a doctor if your symptoms do not improve after 7 days, if they worsen, or if you experience any severe side effects such as allergic reactions or signs of systemic toxicity. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged application over large areas may increase the risk of systemic absorption of lidocaine, leading to potential toxicity. Calcium dobesilate is generally well tolerated, but long-term safety data for topical use are limited. Regular follow-up with your doctor is recommended to assess continued need and monitor for any adverse effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Compression therapy

Wearing compression stockings can help reduce swelling and improve venous return.

Evidence: Well-established
Leg elevation

Elevating legs above heart level several times a day reduces swelling.

Evidence: Well-established
Oral venoactive drugs

Medications like diosmin and hesperidin can be taken orally for venous insufficiency.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions between this medicine and vaccines. Continue with routine vaccinations as per schedule.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and heat. If you are traveling across time zones, continue applying as per your usual schedule; no time adjustment is needed for topical use.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old woman with chronic leg swelling and pain due to venous insufficiency.
She was prescribed this medicine to apply twice daily. After a week, she noticed reduced swelling and less heaviness in her legs. She also started wearing compression stockings and elevating her legs, which further improved her symptoms.
💡 Lesson: Combining this medicine with lifestyle measures like compression and leg elevation can enhance relief from venous symptoms.
👤 A 35-year-old man with a minor sports injury causing localized pain and swelling.
He applied this medicine to the affected area three times a day. The pain subsided within 30 minutes of application, and the swelling decreased over two days. He was careful not to apply it to any broken skin.
💡 Lesson: This medicine provides effective temporary relief for minor injuries when used as directed, but it should not replace medical evaluation for serious injuries.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The numbing effect starts within 5-10 minutes, while the anti-swelling effect may take a few days of regular use.

Q: Can I use this medicine on open wounds?

A: No, it should not be applied to open wounds or infected skin. Consult a doctor for proper wound care.

Q: Is this medicine safe for children?

A: It is not recommended for children under 12 without medical advice. Consult a pediatrician.

Q: What should I do if I miss a dose?

A: Apply it as soon as you remember, but if it's almost time for the next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • Is it safe to use during pregnancy?
  • How long does it take to work?
  • Can I use it with other creams?
  • What if I accidentally swallow it?
  • Does it cause drowsiness?

🔄 Substitutes for h2piles rectal cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used on any skin problem.
    Fact: It is specifically for pain and swelling related to venous issues and minor injuries. It should not be used on open wounds or infections.
  • Myth: More cream means faster relief.
    Fact: Applying more than the recommended amount does not speed up relief and may increase the risk of side effects.
  • Myth: It is safe to use indefinitely.
    Fact: Prolonged use without medical supervision is not recommended. Consult a doctor if symptoms persist beyond 7 days.

🔄 Alternative Options

Generic Alternatives

  • Lidocaine 3% w/w + Calcium Dobesilate 0.25% w/w cream (various manufacturers)

Brand Alternatives

  • Hemolit Cream

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Lidocaine 3% + Calcium Dobesilate 0.25%","route":"Topical","primary_use":"Venous insufficiency, localized pain"},{"medicine":"Lidocaine 2% gel","active_ingredients":"Lidocaine 2%","route":"Topical","primary_use":"Local anesthesia"},{"medicine":"Calcium dobesilate 500 mg capsules","active_ingredients":"Calcium dobesilate 500 mg","route":"Oral","primary_use":"Venous insufficiency"}]

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