gynostatum 2% vaginal cream - Clotrimazole (2% w/w) medicine

Azcool 2% Dusting Powder: Complete Guide to Uses, Dosage, and Safety

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🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Not established from the available information. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat, or difficulty breathing.
  • Signs of secondary bacterial infection such as increased pain, pus, or fever.
  • No improvement after 2 weeks of consistent use.
  • Infection spreads to other parts of the body.
  • Severe blistering or peeling of the skin.
  • Symptoms worsen after starting the medicine.

If experiencing severe symptoms, call emergency services immediately.

What is gynostatum 2% vaginal cream used for?

This medicine is a topical antifungal powder containing clotrimazole 2% w/w. It is used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm. Apply a thin layer to the affected area once or twice daily for 2 to 4 weeks.

  • Generic Name: Clotrimazole (2% w/w)
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gynostatum 2% vaginal cream के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोट्रिमाजोल 2% w/w युक्त एक एंटीफंगल पाउडर है। इसका उपयोग त्वचा के फंगल संक्रमण जैसे पैरों में फंगस (एथलीट फुट), जांघों में खुजली (जॉक इच), दाद और कैंडिडा संक्रमण के इलाज के लिए किया जाता है। यह पाउडर नमी को सोखता है और फंगस को बढ़ने से रोकता है। इसे प्रभावित क्षेत्र पर दिन में एक या दो बार लगाएं।

साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित है। कुछ लोगों को लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूखापन हो सकता है। ये लक्षण आमतौर पर अपने आप ठीक हो जाते हैं। यदि गंभीर एलर्जी जैसे सूजन, चकत्ते या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के निर्देशानुसार करें। लगाने से पहले प्रभावित क्षेत्र को साफ और सूखा करें। आंखों, मुंह और नाक के संपर्क में न आने दें। बच्चों की पहुंच से दूर रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। यदि 2 सप्ताह में सुधार न हो तो डॉक्टर से मिलें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 gynostatum 2% vaginal cream Uses & Benefits

[{"condition":"Athlete's foot (tinea pedis)","description":"Treats fungal infection of the feet, especially between the toes, reducing itching, burning, and scaling.","evidence":"Well-established"},{"condition":"Jock itch (tinea cruris)","description":"Effective against fungal infection in the groin area, helping to relieve itching and rash.","evidence":"Well-established"},{"condition":"Ringworm (tinea corporis)","description":"Used to treat circular, red, scaly patches on the body caused by dermatophytes.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis","description":"Treats skin infections caused by Candida yeast, often in moist skin folds.","evidence":"Well-established"},{"condition":"Pityriasis versicolor","description":"May help in treating this fungal infection that causes light or dark patches on the skin.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Fungal diaper rash","description":"Sometimes recommended by pediatricians for diaper rash with a confirmed fungal component.","evidence":"Limited"},{"condition":"Prevention of fungal infections in high-risk individuals","description":"May be used prophylactically in people prone to recurrent fungal infections, such as athletes or those with diabetes.","evidence":"Limited"}]

Primary treatment for: Fungal skin infections

Also treats: Athlete's foot, Jock itch, Ringworm, Cutaneous candidiasis

📋 Drug Information

Generic Name(s)Clotrimazole (2% w/w)
Brand Namegynostatum 2% vaginal cream
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Clean and dry the affected area thoroughly before applying the powder to enhance its effectiveness.
2
Apply the powder twice daily for best results, or as directed by your doctor.
3
Continue using the powder for the full prescribed duration, even if symptoms improve, to prevent recurrence.
4
Avoid sharing towels, clothing, or footwear with others to prevent spreading the infection.
5
Wear loose-fitting, breathable clothing and cotton socks to keep the skin dry.
6
If the infection does not improve within 2 weeks, consult a doctor for further evaluation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Itchy, scaly rash in skin folds
This medicine is commonly used for fungal infections in skin folds.
Likely Use
❌
Fever
This medicine is not used to treat fever.
Not Primary
✅
Ring-shaped rash
This medicine is effective for ringworm.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption of clotrimazole after topical application to intact skin is minimal. Only a small fraction of the applied dose is absorbed into the systemic circulation. Absorption may increase if the skin is broken or if the medicine is applied to large surface areas or under occlusive dressings.
DistributionDue to minimal systemic absorption, distribution of clotrimazole into body tissues after topical application is limited. It primarily remains at the site of application in the skin layers.
Protein BindingNot established from the available information.
MetabolismAny clotrimazole that is absorbed systemically is metabolized in the liver, primarily by cytochrome P450 enzymes, to inactive metabolites.
Half-LifeNot established from the available information.
ExcretionAbsorbed clotrimazole and its metabolites are excreted mainly in the bile and feces, with a small amount excreted in urine.
BioavailabilityNot established from the available information.
Onset of ActionSymptomatic relief, such as reduction in itching and irritation, may begin within a few days of starting treatment. However, complete resolution of the infection may take several weeks.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action depends on the frequency of application and the severity of the infection. Typically, the medicine needs to be applied once or twice daily for 2 to 4 weeks to ensure complete eradication.

How It Works

Clotrimazole works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. It binds to and inhibits the enzyme lanosterol 14-alpha-demethylase, which is a cytochrome P450-dependent enzyme. This inhibition leads to the accumulation of 14-methylated sterols, which disrupts the structure and function of the fungal cell membrane. The altered membrane becomes permeable, causing leakage of essential intracellular components such as potassium, amino acids, and proteins. This ultimately results in fungal cell death or inhibition of growth. Clotrimazole is primarily fungistatic at lower concentrations but can be fungicidal at higher concentrations. It is effective against a wide range of dermatophytes, yeasts, and some gram-positive bacteria.

Mechanism Steps

1
Binding to fungal enzyme: Clotrimazole binds to the fungal cytochrome P450 enzyme lanosterol 14-alpha-demethylase.
2
Inhibition of ergosterol synthesis: This binding inhibits the conversion of lanosterol to ergosterol, a key component of the fungal cell membrane.
3
Accumulation of toxic sterols: The inhibition leads to the accumulation of 14-methylated sterols, which are toxic to the fungus.
4
Membrane disruption: The fungal cell membrane becomes structurally compromised and more permeable.
5
Leakage of cellular contents: Essential ions and molecules leak out of the fungal cell, leading to impaired function.
6
Fungal growth inhibition or death: The fungus is either inhibited from growing (fungistatic) or killed (fungicidal), depending on the concentration.

💡 How to Take gynostatum 2% vaginal cream

Strength: Dusting powder containing clotrimazole 2% w/w.

1Wash your hands thoroughly before and after applying the powder.
2Clean and dry the affected area gently.
3Sprinkle a thin layer of powder over the affected area.
4If desired, rub it in gently with clean fingers.
5Avoid inhaling the powder.
6Do not cover the area with tight bandages unless directed by a doctor.
7Use regularly for the full duration prescribed.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area and surrounding skin once or twice daily, or as directed by your doctor. Clean and dry the area before application. The duration of treatment depends on the type and severity of the infection, but typically ranges from 2 to 4 weeks. For athlete's foot, continue treatment for at least 2 weeks after symptoms disappear to prevent recurrence. Dose must be individualized by a qualified clinician based on indication, age, and clinical response.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, they should use it with caution and under medical supervision.
Renal ImpairmentNo dosage adjustment is required for patients with renal impairment due to minimal systemic absorption.
Hepatic ImpairmentNo dosage adjustment is required for patients with hepatic impairment due to minimal systemic absorption.
Maximum Daily DoseNot established from the available information. Use as directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of gynostatum 2% vaginal cream

✅ Common Side Effects

Mild burning or stinging at application site (Common (1-10%))
Usually resolves on its own. If it persists or worsens, consult your doctor.
Itching or redness (Common (1-10%))
May indicate irritation. Discontinue if severe and consult a doctor.
Skin dryness or peeling (Uncommon (0.1-1%))
Apply a moisturizer if needed. Consult a doctor if it continues.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, hives, swelling of face, lips, or throat, or difficulty breathing.
Severe contact dermatitis (Rare (<0.1%))
Stop using the medicine and consult a doctor if you develop severe redness, blistering, or swelling.

⚠️ Rare Side Effects

Secondary bacterial infection
Consult a doctor if you notice increased pain, pus, or fever.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity or allergy to clotrimazole or any other ingredient in this medicine.","Do not use on the eyes, mouth, or vagina unless specifically directed by a doctor.","Not for internal use."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.","Do not use on large areas of broken skin or for prolonged periods without medical advice.","If symptoms persist after 2 weeks of treatment, consult a doctor.","Discontinue use if irritation or allergic reaction occurs.","Keep out of reach of children.","Pregnant or breastfeeding women should consult a doctor before use.","Do not use if the packaging is damaged or the expiry date has passed."]

🤱 Lactation Safety

It is not known whether clotrimazole passes into breast milk after topical application. However, systemic absorption is minimal. Consult your doctor before using this medicine while breastfeeding. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

This medicine is for topical use. Accidental ingestion may cause gastrointestinal upset. If swallowed, seek medical attention immediately. Overdose from topical application is unlikely due to minimal systemic absorption. In case of excessive application, wipe off the excess powder and rinse the area with water.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Use this medicine exactly as directed by your doctor or as described on the label. Clean and dry the affected area thoroughly before applying the powder. Apply a thin layer and rub it in gently if needed. Wash your hands before and after application to avoid spreading the infection. Avoid contact with eyes, nose, mouth, and other mucous membranes. Do not use this medicine on large areas of broken skin or for prolonged periods without medical supervision. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Do not share this medicine with others, even if they have similar symptoms. If your condition does not improve after two weeks of regular use, or if it worsens, stop using it and consult a doctor. Do not use this medicine after the expiry date. Store it in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients can use this medicine safely, but they should be monitored for skin irritation. They may have thinner skin, so gentle application is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Topical clotrimazole is generally considered safe, but medical advice is recommended.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before applying this powder to surgical wounds. It is not meant for use on open wounds.

🦷 Dental Procedures

No specific considerations for dental procedures. This medicine is for topical skin use only.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Wear loose-fitting, breathable clothing.
😴
Avoid sharing personal items like towels and shoes.
💧
Use antifungal powder in shoes to prevent reinfection.
🧘
Maintain good hygiene, especially in warm, humid weather.

🏋️ Exercise Considerations

You can continue exercising, but keep the affected area dry. If you have athlete's foot, wear clean socks and change them after exercise. Avoid using communal showers or locker rooms until the infection clears.

🥗 Diet Recommendations

Include probiotics like yogurt to support overall health.
Reduce sugar intake as it may promote fungal growth.
Stay hydrated to maintain healthy skin.

💼 Impact on Daily Work & Life

This medicine does not affect your ability to drive or operate machinery. You can continue your daily activities as usual.

🛑 When to Stop This Medicine

Stop using this medicine if you experience a severe allergic reaction or if your symptoms worsen. Do not stop prematurely if symptoms improve; complete the full course to prevent recurrence. Consult your doctor before stopping if you have been using it for a long time.

📅 Long-Term Use Effects

Long-term use of this medicine is generally not recommended unless advised by a doctor. Prolonged use may lead to skin irritation or secondary infections. If you need to use it for more than 4 weeks, consult your doctor for evaluation.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Keeping the skin dry and clean

Essential for preventing and managing fungal infections.

Evidence: Well-established
Using absorbent powders

Helps keep skin folds dry.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging to avoid confusion. Keep a copy of your prescription if you are traveling internationally. Store it in a cool, dry place, and avoid leaving it in hot cars or direct sunlight. If you are crossing time zones, continue applying as per your usual schedule; no adjustment is needed for topical medications. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itchy, scaly feet
He had been suffering from athlete's foot for months. His doctor prescribed this medicine. He applied it twice daily after washing and drying his feet. Within a week, the itching reduced significantly, and after 3 weeks, the infection cleared. He continued for another week as advised.
💡 Lesson: Consistent use and keeping the feet dry are key to treating athlete's foot.
👤 A 28-year-old woman with jock itch
She developed an itchy rash in her groin area after starting a new workout routine. Her doctor recommended this medicine. She applied it twice daily and wore loose cotton underwear. The rash improved in 10 days, and she completed the full 2-week course.
💡 Lesson: Proper hygiene and completing the full course prevent recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief from itching within a few days, but complete healing may take 2 to 4 weeks.

Q: Can I use it on broken skin?

A: It is best to avoid using on broken skin unless advised by a doctor.

Q: Is it safe to use with other skin products?

A: Generally yes, but consult your doctor or pharmacist to avoid any interactions.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this powder on my face?
  • How long should I use this powder?
  • Is it safe for children?
  • Can I use it during pregnancy?
  • What if I miss a dose?
  • Does it interact with other medicines?

🔄 Substitutes for gynostatum 2% vaginal cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Clotrimazole powder can cure all skin rashes.
    Fact: It only treats fungal infections. Other rashes may require different treatments.
  • Myth: You can stop using the powder as soon as symptoms disappear.
    Fact: You should complete the full course to prevent recurrence.
  • Myth: Clotrimazole powder works instantly.
    Fact: It may take several days to weeks for full effect.

🔄 Alternative Options

Generic Alternatives

  • Clotrimazole 2% w/w dusting powder

Brand Alternatives

  • Candid Dusting Powder
  • Canesten Dusting Powder
  • Clotrimazole Dusting Powder

📊 Comparison with Similar Medicines

[{"medicine":"Clotrimazole","class":"Imidazole antifungal","spectrum":"Broad","frequency":"Once or twice daily"},{"medicine":"Miconazole","class":"Imidazole antifungal","spectrum":"Broad","frequency":"Twice daily"},{"medicine":"Terbinafine","class":"Allylamine antifungal","spectrum":"Dermatophytes","frequency":"Once or twice daily"}]

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