candizole 2% vaginal cream - Clotrimazole (2% w/w) medicine

candizole 2% vaginal cream

4.4 (17 reviews)
๐Ÿญ Bal Pharma Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is candizole 2% vaginal cream used for?

Candid-V Gel (Clotrimazole) is used to treat ANTI INFECTIVES. It contains Clotrimazole (2% w/w), which Inhibits fungal cytochrome P450 14ฮฑ-demethylase, disrupting ergosterol synthesi. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clotrimazole
  • Manufacturer: Bal Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š candizole 2% vaginal cream Uses & Benefits

Vulvovaginal candidiasis (yeast infections).

Off-label uses: Oral thrush (topical application), Diaper rash (topical)

๐Ÿ“‹ Drug Information

Generic Name(s)Clotrimazole
Brand NameCandid-V Gel
ManufacturerBal Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical (intravaginal).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption following topical application; approximately 0.5% absorbed through intact skin.
DistributionDistributed locally in vaginal tissues; negligible systemic distribution.
Protein BindingNot applicable due to minimal systemic absorption.
MetabolismHepatic metabolism to inactive metabolites if absorbed.
Half-LifeNot applicable for topical use; systemic half-life is 3.5-6 hours if absorbed.
ExcretionPrimarily fecal (biliary) and renal excretion of metabolites.
BioavailabilityNegligible systemic bioavailability (<1%).
Onset of ActionRelief of symptoms within 24-72 hours.
Peak Plasma TimeNot applicable due to minimal absorption.
Duration of ActionTherapeutic effect persists for several days after application.

How It Works

Inhibits fungal cytochrome P450 14ฮฑ-demethylase, disrupting ergosterol synthesis and increasing membrane permeability.

Mechanism Steps

1Clotrimazole binds to fungal cytochrome P450 14ฮฑ-demethylase.
2Inhibits conversion of lanosterol to ergosterol.
3Depletes ergosterol in fungal cell membrane.

๐Ÿ’ก How to Take candizole 2% vaginal cream

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of candizole 2% vaginal cream

โœ… Common Side Effects

  • Vaginal burning
  • Itching
  • Irritation

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction (rare)
  • Angioedema

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Urticaria

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tacrolimus Major Increased tacrolimus levels and nephrotoxicity risk
Sirolimus Major Increased sirolimus levels
Warfarin Moderate Enhanced anticoagulant effect
Corticosteroids Moderate Increased corticosteroid levels
Oral contraceptives Minor Reduced contraceptive efficacy (theoretical)

๐Ÿšจ Major Interactions

  • Tacrolimus
  • Sirolimus

โšก Moderate Interactions

  • Warfarin
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to clotrimazole or any component.

๐Ÿ“Š Monitoring Parameters

Clinical response; resolution of symptoms.

๐Ÿคฑ Lactation Safety

Safe; minimal systemic absorption unlikely to affect infant.

๐Ÿ’Š Overdose Management

Unlikely due to topical use; if ingested, symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for candizole 2% vaginal cream

View All

Alternative brands with exact same active ingredient (Clotrimazole (2% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

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