Folisurge 75 Injection: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain (more than 1 kg per day)
- Difficulty breathing or shortness of breath
- Decreased urine output
- Sudden severe pelvic pain
- Swelling, pain, or redness in one leg
- Chest pain or palpitations
- Severe allergic reaction (rash, itching, swelling of face or throat)
If experiencing severe symptoms, call emergency services immediately.
What is gynonys 75iu injection used for?
This medicine is a recombinant follicle stimulating hormone injection used to treat infertility by stimulating egg production in women and sperm production in men. It is given under the supervision of a fertility specialist.
- Generic Name: Recombinant follicle stimulating hormone (75IU)
- Manufacturer: Sanzyme Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 gynonys 75iu injection के बारे में (Hindi Summary)
उपयोग: यह दवा रीकॉम्बिनेंट फॉलिकल स्टिमुलेटिंग हार्मोन (75 आईयू) का इंजेक्शन है, जिसका उपयोग महिलाओं में ओव्यूलेशन को प्रेरित करने और पुरुषों में शुक्राणु उत्पादन को बढ़ाने के लिए किया जाता है। यह आमतौर पर पीसीओएस, आईवीएफ और अन्य प्रजनन उपचारों में उपयोग की जाती है। इसका उपयोग केवल प्रजनन विशेषज्ञ की देखरेख में ही किया जाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, सूजन, सिरदर्द, पेट दर्द, मतली और ओवरी में हल्की सूजन शामिल हैं। गंभीर दुष्प्रभावों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम (ओएचएसएस), ओवेरियन टॉर्शन, कई गर्भधारण और एलर्जी प्रतिक्रियाएं शामिल हैं। यदि आपको गंभीर पेट दर्द, तेजी से वजन बढ़ना, सांस लेने में कठिनाई या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग केवल प्रजनन विशेषज्ञ की देखरेख में ही करें। बिना प्रशिक्षण के स्वयं इंजेक्शन न लगाएं। उपचार के दौरान अल्ट्रासाउंड और रक्त परीक्षण से नियमित निगरानी आवश्यक है। गंभीर पेट दर्द, सूजन, तेजी से वजन बढ़ना या सांस लेने में कठिनाई होने पर तुरंत डॉक्टर को बताएं। यदि आप गर्भधारण नहीं करना चाहतीं तो प्रभावी गर्भनिरोधक उपाय अपनाएं। धूम्रपान और शराब से बचें।
💊 gynonys 75iu injection Uses & Benefits
[{"condition":"Ovulation induction in polycystic ovary syndrome (PCOS)","description":"Used to stimulate the development and release of a mature egg in women who do not ovulate regularly due to PCOS.","evidence":"Well-established"},{"condition":"Controlled ovarian hyperstimulation for assisted reproductive technology (ART)","description":"Used to induce multiple follicle development in women undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).","evidence":"Well-established"},{"condition":"Hypogonadotropic hypogonadism in men","description":"Used to stimulate spermatogenesis in men with low gonadotropin levels, often in combination with human chorionic gonadotropin (hCG).","evidence":"Well-established"}]
Off-label uses: [{"condition":"Luteal phase support","description":"Occasionally used off-label to support the luteal phase in some fertility protocols, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Infertility due to ovulatory disorders
Also treats: Polycystic ovary syndrome (PCOS), Hypogonadotropic hypogonadism in men
📋 Drug Information
| Generic Name(s) | Recombinant follicle stimulating hormone (75IU) |
| Brand Name | gynonys 75iu injection |
| Manufacturer | Sanzyme Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Gonadotropins |
| Route of Administration | Parenteral (subcutaneous or intramuscular injection) |
| Storage | Store in a refrigerator at 2°C to 8°C. Do not freeze. Keep the container in the outer carton to protect from light. Once reconstituted, use immediately or as directed by the manufacturer. |
| Shelf Life | Refer to the packaging for the expiry date. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains recombinant follicle stimulating hormone, which binds to specific follicle stimulating hormone receptors on the surface of granulosa cells in the ovaries and Sertoli cells in the testes. This binding activates intracellular signalling pathways that promote follicular growth, oestrogen production, and spermatogenesis. In women, it stimulates the recruitment and maturation of ovarian follicles, leading to increased oestradiol levels and preparation for ovulation. In men, it supports the development of spermatozoa by acting on Sertoli cells.
Mechanism Steps
💡 How to Take gynonys 75iu injection
Strength: Injection: 75 IU per vial or as specified by the manufacturer.
Dosage Information
| Adult Dosage | The dose of this medicine is highly individualised and depends on the indication, the patient's response, and the specific treatment protocol. For ovulation induction, a typical starting dose might be 75 IU daily, but it can be adjusted based on ovarian response. For assisted reproductive technology, doses may range from 150 to 300 IU daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your fertility specialist's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not intended for use in elderly patients. Safety and efficacy have not been established in this population. |
| Renal Impairment | No specific dose adjustments are recommended for renal impairment, but use with caution and monitor closely. |
| Hepatic Impairment | No specific dose adjustments are recommended for hepatic impairment, but use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum daily dose should not exceed that prescribed by your fertility specialist. Doses above 450 IU per day are not usually recommended. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of gynonys 75iu injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| GnRH antagonists | Major | |
| GnRH agonists | Major | |
| Clomiphene citrate | Moderate | |
| NSAIDs | Minor |
🚨 Major Interactions
- Gonadotropin-releasing hormone (GnRH) antagonists
- Gonadotropin-releasing hormone (GnRH) agonists
⚡ Moderate Interactions
- Clomiphene citrate
🍷 Alcohol Interaction
It is advisable to avoid alcohol while using this medicine, as alcohol can reduce fertility and may increase the risk of liver problems. Consult your doctor for personalised advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to follicle stimulating hormone or any excipient","Primary ovarian failure","Uncontrolled thyroid or adrenal dysfunction","Tumours of the ovary, breast, uterus, testis, pituitary or hypothalamus","Pregnancy and breastfeeding","Abnormal uterine bleeding of unknown cause","Ovarian cysts or enlargement not due to polycystic ovary syndrome"]
⚠️ Warnings & Precautions
["This medicine should only be prescribed by a fertility specialist experienced in the management of reproductive disorders.","Ovarian hyperstimulation syndrome (OHSS) is a serious risk; monitor closely with ultrasound and clinical assessment.","Multiple pregnancies are a common complication; discuss the risks with your doctor.","There is an increased risk of thromboembolic events; assess individual risk factors before treatment.","In men, monitor testosterone levels and semen parameters during therapy.","Do not use if the solution is discoloured or contains particulate matter.","Inform your doctor if you have a history of allergies, liver disease, kidney disease, or blood clotting disorders."]
🤱 Lactation Safety
It is not known whether recombinant follicle stimulating hormone is excreted in human breast milk. This medicine is not intended for use during breastfeeding. Consult your doctor for guidance.
💊 Overdose Management
Overdose may lead to ovarian hyperstimulation syndrome (OHSS). If you suspect an overdose, contact your doctor immediately. Treatment is supportive and may include hospitalisation, intravenous fluids, and monitoring of electrolytes and ovarian size. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, contact your fertility specialist for advice. Do not double the dose to make up for a missed one. The dosing schedule is critical for treatment success, so follow your doctor's instructions carefully.
Additional Safety Advice
This medicine must only be used under the supervision of a fertility specialist. Do not self-administer unless you have been properly trained. Regular monitoring with ultrasound and blood tests is essential to assess ovarian response and adjust the dose. Report any severe abdominal pain, bloating, rapid weight gain, or difficulty breathing immediately, as these may be signs of ovarian hyperstimulation syndrome. Use effective contraception if you are not trying to conceive, as this medicine can increase the chance of multiple pregnancies. Avoid alcohol and smoking during treatment. Inform your doctor if you have a history of thyroid, adrenal, or liver problems, or if you have had previous ovarian surgery. Store the injection as advised by the manufacturer, and never use it if the solution is discoloured or contains particles.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly patients. Safety and efficacy have not been established in this population.
🤰 Pregnancy Planning (TTC)
This medicine is used to induce ovulation and is part of fertility treatment. If you are planning pregnancy, consult your fertility specialist for a comprehensive evaluation and personalised treatment plan. It is not recommended to use this medicine without medical supervision.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your fertility specialist before starting this medicine. The risk of thromboembolic events may be increased post-surgery, and appropriate precautions should be taken.
🦷 Dental Procedures
There are no specific dental procedure considerations with this medicine. However, inform your dentist about all medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid intense or high-impact activities during ovarian stimulation to reduce the risk of ovarian torsion. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mild side effects like headache or abdominal discomfort, which could affect your ability to drive or operate machinery. It is advisable to avoid driving if you feel unwell. Treatment requires frequent clinic visits for monitoring, which may impact your work schedule. Discuss with your employer for flexibility.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your fertility specialist. Treatment duration is determined by your response and the specific protocol. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is generally limited to the duration of fertility treatment cycles. There is no evidence of long-term adverse effects when used as prescribed. However, repeated cycles may increase the risk of ovarian hyperstimulation syndrome and multiple pregnancies. Regular monitoring is essential to minimise risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral medication used for ovulation induction in some women with PCOS.
Evidence: Well-establishedAn oral aromatase inhibitor used for ovulation induction, often with fewer side effects than clomiphene.
Evidence: Well-establishedWeight loss, diet, and exercise can improve ovulation in women with PCOS.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, it is advisable to be up to date with routine vaccinations before starting fertility treatment. Consult your doctor for personalised advice.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in the original carton to protect from light
❌ DON'T
Do not expose to direct sunlight
✅ DO
Use immediately after reconstitution
❌ DON'T
Do not store reconstituted solution for later use
✈️ Traveling with This Medicine
When travelling with this medicine, carry it in its original packaging with the prescription label. Keep it in a cool bag with ice packs to maintain the cold chain (2°C to 8°C). Carry a copy of your prescription and a letter from your doctor explaining the medical need. Check airline regulations for carrying injections and sharps. If crossing time zones, consult your doctor about adjusting the timing of doses. Always declare the medication at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Follicular growth can be observed within 7 to 14 days of starting treatment, but the exact time varies depending on individual response.
A: No, this medicine must only be used under the supervision of a fertility specialist due to the risk of serious complications.
A: Contact your fertility specialist for advice. Do not double the dose.
A: This medicine is not intended for use during pregnancy. It should be discontinued if pregnancy occurs.
🤔 Common Patient Concerns
🔄 Substitutes for gynonys 75iu injection
View AllAlternative brands with exact same active ingredient:
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inducent 75iu injectionAlkem Laboratories Ltd ₹453.52 24.1% CHEAPER
-
humegon 75iu injectionOrganon (India) Ltd ₹595.00 0.5% CHEAPER
-
nugon 75iu injectionAbbott ₹650.00 8.7% COSTLIER
-
stimufol p 75iu injectionIntas Pharmaceuticals Ltd ₹700.00 17.1% COSTLIER
-
Follitec 75IU InjectionUnited Biotech Pvt Ltd ₹750.00 25.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: This medicine increases the chance of ovulation and pregnancy, but success depends on many factors including age, cause of infertility, and overall health. - Myth: This medicine can be used without medical supervision.
Fact: This medicine must only be used under the supervision of a fertility specialist due to the risk of serious complications like ovarian hyperstimulation syndrome.
🔄 Alternative Options
Generic Alternatives
- Recombinant follicle stimulating hormone
Brand Alternatives
- Folisurge 75 IU Injection