gulspas a 100mg/80mg tablet - Drotaverine (100mg) + Aceclofenac (80mg) medicine

Gulspas A 100mg/80mg Tablet: Complete Medicine Guide

No reviews yet
🏭 Salveo Lifecare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. This medicine should be avoided during pregnancy, especially in the third trimester, unless clearly needed and advised by a doctor. Aceclofenac may cause premature closure of the ductus arteriosus and other complications. Drotaverine safety in pregnancy is not well established. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising
  • Severe skin rash or blisters

If experiencing severe symptoms, call emergency services immediately.

What is gulspas a 100mg/80mg tablet used for?

This medicine is a combination of Drotaverine (100 mg) and Aceclofenac (80 mg) used to relieve pain and spasm in conditions like abdominal cramps, biliary colic, renal colic, and dysmenorrhea. It works by relaxing smooth muscles and reducing inflammation. It should be taken with food and only as prescribed by a doctor.

  • Generic Name: Drotaverine (100mg) + Aceclofenac (80mg)
  • Manufacturer: Salveo Lifecare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gulspas a 100mg/80mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ड्रोटावेरिन 100 मिलीग्राम और एसीक्लोफेनाक 80 मिलीग्राम का संयोजन है। इसका उपयोग पेट की ऐंठन, पित्ताशय की ऐंठन, गुर्दे की ऐंठन, मासिक धर्म के दर्द और मांसपेशियों की ऐंठन से जुड़े दर्द के इलाज के लिए किया जाता है। यह दवा मांसपेशियों को आराम देकर और सूजन को कम करके दर्द से राहत देती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, एलर्जी प्रतिक्रिया, गुर्दे की समस्या और लीवर की समस्या शामिल हो सकती है। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब न लें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं या गर्भधारण की योजना बना रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 gulspas a 100mg/80mg tablet Uses & Benefits

[{"condition":"Abdominal cramps and spasms","description":"Relieves smooth muscle spasm in the gastrointestinal tract, reducing cramping and pain.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Helps relax the biliary tract smooth muscle, relieving pain associated with gallstones or biliary spasm.","evidence":"Moderate"},{"condition":"Renal colic","description":"Used to relieve pain from ureteral spasm, often in combination with other analgesics.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"Reduces uterine cramps and associated pain during menstruation.","evidence":"Moderate"},{"condition":"Musculoskeletal pain with spasm","description":"Provides anti-inflammatory and analgesic effects for conditions like low back pain with muscle spasm.","evidence":"Limited"}]

Off-label uses: [{"condition":"Irritable bowel syndrome","description":"Sometimes prescribed to relieve abdominal cramping in IBS, though not a standard first-line treatment.","evidence":"Limited"},{"condition":"Post-operative spasm","description":"Occasionally used to manage smooth muscle spasm after certain surgeries.","evidence":"Limited"}]

Primary treatment for: Painful smooth muscle spasm with inflammation

Also treats: Biliary colic, Renal colic, Dysmenorrhea, Musculoskeletal pain with spasm

📋 Drug Information

Generic Name(s)Drotaverine (100mg) + Aceclofenac (80mg)
Brand Namegulspas a 100mg/80mg tablet
ManufacturerSalveo Lifecare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid alcohol completely while taking this medicine to prevent gastrointestinal bleeding.
3
Do not drive or operate heavy machinery if you experience dizziness or drowsiness.
4
Inform your doctor if you have a history of stomach ulcers, heart disease, kidney or liver problems, or asthma.
5
Do not take other NSAIDs or painkillers concurrently unless specifically advised by your doctor.
6
Use the lowest effective dose for the shortest duration possible.
7
Report any unusual bleeding, bruising, or dark stools immediately.
8
If symptoms persist beyond 7 days, consult your doctor for reassessment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Biliary colic
This medicine may be prescribed for this.
Likely Use
✅
Renal colic
This medicine may be prescribed for this.
Likely Use
✅
Menstrual cramps
This medicine may be prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDrotaverine is rapidly absorbed after oral administration. Aceclofenac is also well absorbed from the gastrointestinal tract. Food may slightly delay absorption but does not significantly affect the extent of absorption.
DistributionBoth Drotaverine and Aceclofenac are widely distributed in body tissues. Aceclofenac is highly protein-bound. Specific volume of distribution data for the combination is not established from the available information.
Protein BindingAceclofenac is approximately 99% bound to plasma proteins. Drotaverine binding is not well characterized but is likely high. Not established from the available information for the combination.
MetabolismDrotaverine is extensively metabolized in the liver. Aceclofenac is metabolized in the liver, primarily by cytochrome P450 enzymes, to inactive metabolites.
Half-LifeThe elimination half-life of Drotaverine is approximately 8 to 12 hours. Aceclofenac has a plasma half-life of approximately 4 hours. Not established from the available information for the combination product.
ExcretionMetabolites of both drugs are excreted primarily in urine and to a lesser extent in feces. Not established from the available information for the combination.
BioavailabilityThe oral bioavailability of Drotaverine is approximately 25% to 90% depending on formulation. Aceclofenac has a bioavailability of approximately 80% to 100%. Not established from the available information for this specific combination.
Onset of ActionDrotaverine typically begins to relieve spasm within 30 to 60 minutes after oral administration. Aceclofenac provides pain relief within 30 to 60 minutes. The combined onset is generally within 1 hour.
Peak Plasma TimePeak plasma concentrations for Drotaverine are reached in about 1 to 2 hours. Aceclofenac peaks in about 1.5 to 3 hours. Not established from the available information for the combination.
Duration of ActionThe antispasmodic effect of Drotaverine lasts approximately 4 to 6 hours. Aceclofenac provides pain relief for about 4 to 6 hours. The combination may require dosing two to three times daily.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Drotaverine is a selective phosphodiesterase-4 inhibitor that increases cyclic adenosine monophosphate (cAMP) levels in smooth muscle cells, leading to relaxation and relief of spasm. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby decreasing inflammation and pain.

Mechanism Steps

1
Drotaverine inhibits phosphodiesterase-4: Drotaverine selectively inhibits phosphodiesterase-4 in smooth muscle cells, preventing the breakdown of cyclic adenosine monophosphate (cAMP).
2
Increased cAMP causes smooth muscle relaxation: Elevated cAMP levels reduce intracellular calcium and inhibit myosin light chain kinase, leading to relaxation of smooth muscle and relief of spasm.
3
Aceclofenac inhibits cyclooxygenase enzymes: Aceclofenac blocks cyclooxygenase-1 and cyclooxygenase-2 enzymes, reducing the conversion of arachidonic acid to prostaglandins.
4
Reduced prostaglandins decrease inflammation and pain: Lower prostaglandin levels reduce inflammation, swelling, and sensitization of pain receptors, providing analgesic and anti-inflammatory effects.

💡 How to Take gulspas a 100mg/80mg tablet

Strength: Tablet containing Drotaverine 100 mg and Aceclofenac 80 mg.

1Take this medicine orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew.
4Take at the same times each day as prescribed.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.
7Do not stop suddenly without consulting your doctor if you have been on long-term therapy.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally two to three times daily, preferably after meals. The exact dose and duration depend on the condition being treated, its severity, and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is intended for short-term use unless otherwise directed by your doctor.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Avoid in severe kidney impairment (eGFR <30 mL/min). Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Avoid in severe liver impairment. Dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily DoseThe maximum recommended daily dose is not established from the available information. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver toxicity.
Grapefruit juice
Avoid
May increase drug levels and risk of side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gulspas a 100mg/80mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Rest and hydrate. Consult if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Dry mouth (Uncommon (1-5%))
Sip water frequently. Chew sugar-free gum if needed.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical advice if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Cardiovascular events (heart attack, stroke) (Rare (<0.1%))
Seek emergency care for chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek immediate medical attention for rash, blisters, or peeling skin.
Aplastic anemia
Report unusual tiredness, infections, or bleeding to your doctor.
Pancreatitis
Seek medical care for severe upper abdominal pain radiating to back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
SSRIs Moderate
Digoxin Moderate
Antacids Minor
Aspirin Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics)
  • SSRIs
  • Digoxin
  • Oral hypoglycemics

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity. It may also worsen dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to Drotaverine, Aceclofenac, or any other NSAID","Active peptic ulcer or history of recurrent peptic ulcer","Gastrointestinal bleeding or perforation","Severe heart failure","Severe kidney impairment (eGFR

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not drive or operate machinery if you feel dizzy or drowsy.","Inform your doctor if you have a history of stomach ulcers, heart disease, kidney or liver problems, or asthma.","Do not take other NSAIDs concurrently unless advised.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of bleeding, especially if taking anticoagulants.","Do not exceed the recommended dose or duration."]

🤱 Lactation Safety

Not established from the available information. It is not known whether Drotaverine and Aceclofenac pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, abdominal pain, dizziness, and drowsiness. In severe cases, gastrointestinal bleeding, kidney failure, or liver damage may occur. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of gastrointestinal bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, heart disease, kidney or liver problems, or asthma. Do not take this medicine with other NSAIDs unless advised. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution at the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy, especially in the third trimester. Discuss alternative treatment options with your doctor.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain and spasm, but only under medical supervision. It may increase bleeding risk, so inform your surgeon if you are taking it before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise you to stop it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and muscles.
🥗
Stay well hydrated throughout the day.
😴
Include anti-inflammatory foods like fruits, vegetables, and omega-3 rich fish in your diet.
💧
Practice relaxation techniques to reduce muscle tension.
🧘
Get adequate sleep to aid recovery.
🌞
Avoid heavy lifting or strenuous activities that may trigger spasms.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while experiencing acute pain or spasm. Gentle stretching and low-impact activities like walking or swimming may help. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Stay well hydrated with water and clear fluids.
Avoid alcohol and caffeine if they worsen symptoms.
Eat small, frequent meals if you have abdominal cramps.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Most people can continue their daily activities with caution.

🛑 When to Stop This Medicine

Stop taking this medicine if your doctor advises you to, or if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop suddenly if you have been on long-term therapy without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of liver and kidney function is recommended. Use the lowest effective dose for the shortest duration. Do not continue beyond the prescribed period without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and muscle spasm.

Evidence: Well-established
Heat therapy

Applying heat to the affected area can help relax muscles and relieve spasm.

Evidence: Moderate
Relaxation techniques

Deep breathing, meditation, and yoga may help reduce muscle tension.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established from the available information. However, inform your doctor about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip and carry a list of your medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with severe menstrual cramps
She was prescribed this medicine for dysmenorrhea. She took it with food as advised and noticed significant relief within an hour. She avoided alcohol and did not experience any stomach upset. She was advised to use it only during her periods and not continuously.
💡 Lesson: Taking this medicine with food and only as needed for short periods improves tolerability and reduces risk of side effects.
👤 A 50-year-old man with biliary colic
He experienced severe upper abdominal pain due to gallstones. This medicine was prescribed to relieve the spasm and pain. He was monitored for liver function and advised to avoid fatty foods. The pain subsided within a few hours, and he was later advised surgery for gallstones.
💡 Lesson: This medicine provides symptomatic relief but does not treat the underlying cause. Definitive treatment may be needed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving spasm and pain within 1 hour after taking it.

Q: Can I take this medicine on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Can I take this medicine with alcohol?

A: No, avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding and liver toxicity.

Q: Is this medicine safe during pregnancy?

A: This medicine should be avoided during pregnancy, especially in the third trimester, unless clearly needed and advised by your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with other painkillers?

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any type of pain.
    Fact: This medicine is specifically for pain associated with smooth muscle spasm and inflammation. It is not a general painkiller for all types of pain.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: This is a prescription medicine. It should only be taken under medical supervision due to potential serious side effects.
  • Myth: Taking this medicine with alcohol is safe.
    Fact: Alcohol increases the risk of gastrointestinal bleeding and liver toxicity. Avoid alcohol while taking this medicine.
  • Myth: This medicine can be taken long-term without any monitoring.
    Fact: Long-term use requires monitoring of liver and kidney function, and increases the risk of cardiovascular events.

🔄 Alternative Options

Generic Alternatives

  • Drotaverine 100 mg + Aceclofenac 80 mg tablet (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Drotaverine 100 mg + Aceclofenac 80 mg)","composition":"Drotaverine 100 mg + Aceclofenac 80 mg","uses":"Spasm and inflammation pain","onset":"1 hour","duration":"4-6 hours"},{"medicine":"Drotaverine 40 mg tablet","composition":"Drotaverine 40 mg","uses":"Smooth muscle spasm","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Aceclofenac 100 mg tablet","composition":"Aceclofenac 100 mg","uses":"Inflammation and pain","onset":"30-60 minutes","duration":"4-6 hours"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory