glykad 500mg tablet sr - Metformin (500mg) medicine

Almetfor 500mg Tablet: Complete Medicine Guide

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🏭 Salveo Lifecare 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Muscle pain or cramps with difficulty breathing
  • Severe stomach pain with nausea and vomiting
  • Extreme tiredness or weakness
  • Dizziness or lightheadedness
  • Sudden weight loss or loss of appetite
  • Yellowing of skin or eyes
  • Decreased urine output
  • Persistent numbness or tingling in hands or feet

If experiencing severe symptoms, call emergency services immediately.

What is glykad 500mg tablet sr used for?

This medicine contains Metformin 500mg, an oral antidiabetic medicine used to treat type 2 diabetes. It lowers blood sugar by reducing liver glucose production and improving insulin sensitivity. It is taken with meals, usually once or twice daily, as prescribed by a doctor.

  • Generic Name: Metformin (500mg)
  • Manufacturer: Salveo Lifecare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 glykad 500mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा मेटफॉर्मिन 500mg युक्त एक ओरल एंटीडायबिटिक दवा है, जिसका उपयोग टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए किया जाता है। यह शरीर में ब्लड शुगर को कम करने में मदद करती है और इंसुलिन के प्रति शरीर की संवेदनशीलता को बढ़ाती है। यह दवा आमतौर पर खाने के साथ ली जाती है और डॉक्टर के निर्देशानुसार दिन में एक या दो बार ली जा सकती है। यह दवा उन लोगों के लिए नहीं है जिन्हें गंभीर किडनी या लिवर की बीमारी है, या जो बहुत अधिक शराब पीते हैं।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, दस्त, पेट में असहजता, और मुँह में धातु जैसा स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ हफ्तों में ठीक हो जाते हैं। दुर्लभ मामलों में लैक्टिक एसिडोसिस हो सकता है, जिसके लक्षण हैं मांसपेशियों में दर्द, सांस लेने में कठिनाई, पेट दर्द, चक्कर आना और अत्यधिक थकान। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें। लंबे समय तक उपयोग से विटामिन बी12 की कमी हो सकती है।

सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें और बिना सलाह के बंद न करें। इसे खाने के साथ लें ताकि पेट की परेशानी कम हो। दिनभर पर्याप्त पानी पिएं। शराब का सेवन न करें या बहुत कम करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अगर आपको किडनी या लिवर की समस्या है, या आपको कोई सर्जरी या कंट्रास्ट टेस्ट कराना है, तो डॉक्टर को बताएं। नियमित रूप से ब्लड शुगर की जांच कराएं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 glykad 500mg tablet sr Uses & Benefits

[{"condition":"Type 2 diabetes mellitus","description":"First-line oral medicine to lower blood sugar levels in adults and children aged 10 years and older, especially when diet and exercise alone are not enough.","evidence":"Well-established"},{"condition":"Prediabetes","description":"Sometimes prescribed to delay progression to type 2 diabetes in people with high risk, along with lifestyle changes.","evidence":"Moderate"},{"condition":"Polycystic ovary syndrome (PCOS)","description":"Used off-label to improve insulin resistance, restore menstrual cycles, and support ovulation in women with PCOS.","evidence":"Moderate"},{"condition":"Gestational diabetes","description":"May be used in some cases under close medical supervision when insulin is not suitable or available.","evidence":"Limited"}]

Off-label uses: [{"condition":"Weight management in obesity","description":"May help with modest weight loss in people with insulin resistance, but not approved for weight loss alone.","evidence":"Limited"},{"condition":"Non-alcoholic fatty liver disease (NAFLD)","description":"Some studies suggest benefit in improving liver enzymes and insulin resistance, but evidence is not conclusive.","evidence":"Limited"},{"condition":"HIV-associated lipodystrophy","description":"Sometimes used to improve insulin resistance in patients on antiretroviral therapy.","evidence":"Limited"}]

Primary treatment for: Type 2 diabetes mellitus

Also treats: Prediabetes, Polycystic ovary syndrome (PCOS), Gestational diabetes

📋 Drug Information

Generic Name(s)Metformin (500mg)
Brand Nameglykad 500mg tablet sr
ManufacturerSalveo Lifecare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassBiguanides
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Keep away from moisture and direct sunlight. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization recommends metformin as a first-line oral medicine for type 2 diabetes in adults, along with lifestyle modifications.
ICMR GuidelineThe Indian Council of Medical Research recommends metformin as the preferred initial oral antidiabetic agent for type 2 diabetes in India, unless contraindicated.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset and improve tolerability.
2
Stay well hydrated throughout the day, especially during hot weather or exercise.
3
Avoid excessive alcohol consumption as it increases the risk of lactic acidosis.
4
Monitor your blood sugar regularly and keep a record to share with your doctor.
5
Report any unusual muscle pain, difficulty breathing, or extreme tiredness immediately.
6
Do not stop this medicine without consulting your doctor, even if you feel better.
7
Inform your doctor if you are scheduled for surgery or imaging with contrast dye.
8
Get your kidney function and vitamin B12 levels checked periodically as advised.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood sugar levels
This medicine is commonly prescribed for type 2 diabetes.
Likely Use
Frequent urination and excessive thirst
These are symptoms of high blood sugar that this medicine helps control.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Irregular periods in PCOS
This medicine may be prescribed off-label for PCOS.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed mainly from the small intestine. Food reduces the rate but not the extent of absorption. Bioavailability is approximately 50-60% under fasting conditions.
DistributionThis medicine distributes rapidly into body tissues and fluids. It is not significantly bound to plasma proteins.
Protein BindingNegligible protein binding.
MetabolismThis medicine is not metabolized by the liver to any significant extent. It is excreted unchanged in the urine.
Half-LifeApproximately 6.2 hours in plasma and about 17.6 hours in whole blood.
ExcretionThis medicine is excreted unchanged in the urine by active tubular secretion. Renal clearance is about 3.5 times that of creatinine clearance.
Bioavailability50-60% under fasting conditions.
Onset of ActionBlood sugar lowering effect may begin within a few days, but full effect may take 1-2 weeks.
Peak Plasma Time2-3 hours after oral administration.
Duration of ActionApproximately 24 hours for immediate-release formulation when taken as prescribed.

How It Works

This medicine works mainly by reducing glucose production in the liver and improving the body's response to insulin. It also decreases glucose absorption from the intestines and increases glucose uptake by muscles. Unlike some other diabetes medicines, it does not stimulate the pancreas to release more insulin, so it rarely causes low blood sugar when used alone.

Mechanism Steps

1
Inhibition of hepatic gluconeogenesis: This medicine reduces the production of glucose in the liver by inhibiting key enzymes involved in gluconeogenesis.
2
Improved insulin sensitivity: It enhances the sensitivity of muscle and fat cells to insulin, allowing more glucose to enter cells from the bloodstream.
3
Reduced intestinal glucose absorption: This medicine decreases the absorption of glucose from the intestines after meals.
4
Increased peripheral glucose uptake: It promotes glucose uptake and utilization in skeletal muscles and adipose tissue.

💡 How to Take glykad 500mg tablet sr

Strength: Immediate-release tablet, 500 mg.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it with meals to reduce stomach upset.
4Do not crush, chew, or break the tablet unless advised.
5Take it at the same times each day to maintain consistent blood levels.
6If you miss a dose, follow the missed dose instructions.
7Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual starting dose for adults is 500 mg once or twice daily with meals. The dose may be increased gradually based on blood sugar levels and tolerability, up to a maximum of 2550 mg per day in divided doses. The exact dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and blood sugar control.
Pediatric DosageFor children aged 10 years and older, the starting dose is usually 500 mg twice daily with meals. The dose may be increased gradually as advised by the pediatrician. Pediatric dosing is not established for children under 10 years. Consult a pediatrician.
Elderly DosageOlder adults may be more sensitive to the effects of this medicine. Kidney function should be assessed before starting and monitored regularly. The dose should be individualized by a clinician based on renal function and overall health.
Renal ImpairmentDose adjustment is required in kidney impairment. In patients with eGFR 30-45 mL/min/1.73 m², this medicine should be used with caution and at reduced doses. It is contraindicated in patients with eGFR <30 mL/min/1.73 m². Consult your doctor for individualized dosing.
Hepatic ImpairmentThis medicine should be used with caution in patients with liver disease. Dose adjustment may be needed. It is contraindicated in severe liver disease. Consult your doctor for individualized dosing.
Maximum Daily Dose2550 mg per day in divided doses.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with food
Reduces stomach upset and improves tolerability.
Alcohol
Avoid excessive use
Increases risk of lactic acidosis and low blood sugar.
High-fiber foods
May reduce absorption
Take at consistent times to maintain steady levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of glykad 500mg tablet sr

✅ Common Side Effects

Nausea (Common (up to 30%))
Take with food. Usually resolves after a few weeks. Consult doctor if persistent.
Diarrhea (Common (up to 20%))
Stay hydrated. If severe or persistent, consult doctor.
Abdominal discomfort (Common (10-20%))
Take with meals. If it continues, talk to your doctor.
Metallic taste (Uncommon (1-5%))
Usually temporary. Chewing sugar-free gum may help.
Flatulence (Common (10-15%))
Avoid gas-producing foods. Consult doctor if bothersome.

🚨 Serious Side Effects

Lactic acidosis (Rare (<0.1%))
Seek emergency medical attention if you experience muscle pain, trouble breathing, stomach pain, dizziness, or extreme tiredness.
Vitamin B12 deficiency (Uncommon (5-10% with long-term use))
Report symptoms like numbness, tingling, or anemia. Periodic blood tests may be needed.
Severe hypoglycemia (Rare when used alone)
If taken with other diabetes medicines, monitor blood sugar. Seek help if symptoms occur.

⚠️ Rare Side Effects

Megaloblastic anemia
Report fatigue, pale skin, or shortness of breath. Vitamin B12 levels may be checked.
Pancreatitis
Seek immediate care for severe abdominal pain radiating to the back.
Hepatitis
Report yellowing of skin or eyes, dark urine, or right upper abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Iodinated contrast media Major
Alcohol Major
Diuretics Moderate
Cimetidine Moderate
NSAIDs Moderate
Corticosteroids Moderate
Beta-blockers Moderate
ACE inhibitors Moderate
Antacids Minor
Vitamin B12 Minor

🚨 Major Interactions

  • Iodinated contrast media
  • Alcohol
  • Diuretics (e.g., furosemide)
  • Cationic drugs (e.g., cimetidine, amiloride)

⚡ Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Beta-blockers
  • ACE inhibitors

🍷 Alcohol Interaction

Avoid excessive alcohol consumption while taking this medicine. Alcohol increases the risk of lactic acidosis and can cause dangerous drops in blood sugar. If you drink alcohol, do so in moderation and only after consulting your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe kidney impairment (eGFR

⚠️ Warnings & Precautions

["Lactic acidosis is a rare but serious complication. Seek immediate medical help if you experience muscle pain, trouble breathing, stomach pain, dizziness, or extreme tiredness.","Kidney function should be assessed before starting and regularly during treatment.","Avoid excessive alcohol consumption.","Temporarily stop this medicine before surgery or imaging with contrast dye, as advised by your doctor.","Vitamin B12 deficiency may occur with long-term use. Periodic monitoring is recommended.","This medicine may cause low blood sugar when used with other diabetes medicines. Monitor blood sugar regularly.","Do not use this medicine for type 1 diabetes or diabetic ketoacidosis."]

🤱 Lactation Safety

This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but monitor the infant for signs of low blood sugar. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause lactic acidosis. Symptoms include severe nausea, vomiting, diarrhea, abdominal pain, muscle pain, difficulty breathing, and extreme tiredness. Seek emergency medical attention immediately. Treatment may include supportive care, hemodialysis to remove the drug, and correction of acidosis.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your clinician. Take the tablet with meals to reduce stomach upset. Drink plenty of water throughout the day. Avoid excessive alcohol consumption while taking this medicine because it increases the risk of lactic acidosis. Inform your doctor if you have kidney or liver problems, heart failure, or if you are scheduled for any surgery or imaging test with contrast dye. Your doctor may ask you to temporarily stop this medicine before such procedures. Check your blood sugar regularly as advised. Report any unusual symptoms such as muscle pain, difficulty breathing, or extreme tiredness immediately. Keep all follow-up appointments and lab tests. Do not share this medicine with anyone else, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults may have reduced kidney function, which increases the risk of lactic acidosis. Kidney function should be assessed before starting and monitored regularly. The dose should be individualized based on renal function. Elderly patients should be monitored for vitamin B12 deficiency and low blood sugar.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. This medicine is generally considered safe during pregnancy, but insulin is often preferred. Your doctor may adjust your treatment plan to ensure optimal blood sugar control before and during pregnancy.

🏥 Post-Surgery Considerations

This medicine may need to be temporarily stopped before surgery and restarted only after kidney function is confirmed normal. Follow your doctor's instructions carefully. Monitor blood sugar closely during the postoperative period.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. No specific precautions are usually needed for routine dental work. However, if you are having surgery or procedures with sedation, your doctor may advise temporary discontinuation.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through balanced diet and regular exercise.
🥗
Eat a diet rich in fiber, whole grains, and lean proteins.
😴
Limit intake of sugary drinks and processed foods.
💧
Engage in at least 30 minutes of moderate exercise most days of the week.
🧘
Monitor your blood sugar regularly as advised by your doctor.
🌞
Get adequate sleep and manage stress effectively.
🚭
Avoid smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Exercise is beneficial for blood sugar control, but intense exercise may cause blood sugar to drop too low, especially if you take other diabetes medicines. Monitor your blood sugar before and after exercise. Stay hydrated and carry a source of fast-acting sugar in case of hypoglycemia.

🥗 Diet Recommendations

Include plenty of non-starchy vegetables.
Choose whole grains over refined grains.
Limit sugary beverages and sweets.
Eat lean proteins like fish, chicken, and legumes.
Include healthy fats from nuts, seeds, and olive oil.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine generally does not affect your ability to work or drive. However, if you experience dizziness or low blood sugar (especially when combined with other diabetes medicines), avoid driving or operating heavy machinery until you feel better. Take your medicine with meals to minimize stomach upset during work hours.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like lactic acidosis, severe allergic reaction, or kidney problems, your doctor may advise stopping it. Always follow your doctor's guidance.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing type 2 diabetes. However, it may lead to vitamin B12 deficiency, which can cause anemia and nerve problems. Regular monitoring of vitamin B12 levels, kidney function, and blood sugar is recommended. Some people may experience gradual decline in kidney function, so periodic assessment is important. This medicine may also reduce the risk of cardiovascular events in people with diabetes.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are essential for managing type 2 diabetes and can complement medicine.

Evidence: Well-established
Other oral antidiabetic medicines

Sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, or insulin may be used if metformin is not suitable.

Evidence: Well-established
Bariatric surgery

May be considered for people with severe obesity and type 2 diabetes.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, people with diabetes should stay up to date with recommended vaccines, including influenza, pneumococcal, and hepatitis B vaccines, as advised by their doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the timing of doses. Carry enough supply for the entire trip plus extra in case of delays. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with newly diagnosed type 2 diabetes
He was prescribed this medicine 500mg twice daily with meals. Initially, he experienced mild nausea and diarrhea, but these improved after two weeks. His blood sugar levels gradually came under control, and he lost 3 kg over three months. He emphasized taking the tablet with food and staying hydrated.
💡 Lesson: Starting with a lower dose and taking it with meals helps minimize stomach side effects. Consistency and lifestyle changes improve outcomes.
👤 A 38-year-old woman with polycystic ovary syndrome (PCOS)
She was prescribed this medicine off-label to help with insulin resistance and irregular periods. After three months, her menstrual cycles became more regular, and her energy levels improved. She also adopted a low-carb diet and regular exercise.
💡 Lesson: This medicine can be beneficial for PCOS under medical supervision, but lifestyle modifications are equally important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within a few days, but full effect may take 1-2 weeks. It may take several weeks to see optimal results.

Q: Can I take this medicine with other diabetes medicines?

A: Yes, but only under medical supervision. Combining with other diabetes medicines may increase the risk of low blood sugar. Your doctor will adjust doses accordingly.

Q: What should I do if I experience side effects?

A: Mild side effects like nausea or diarrhea often improve with time. Taking the medicine with food can help. If side effects are severe or persistent, contact your doctor.

Q: Can I stop taking this medicine if my blood sugar is normal?

A: No, do not stop without consulting your doctor. This medicine controls blood sugar but does not cure diabetes. Stopping it can cause blood sugar to rise again.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Will it cause weight gain?
  • Is it safe during pregnancy?

🔄 Substitutes for glykad 500mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Metformin causes kidney damage.
    Fact: Metformin does not damage the kidneys, but it is excreted by the kidneys. Dose adjustment is needed in kidney disease, and it is contraindicated in severe kidney impairment.
  • Myth: Metformin causes weight gain.
    Fact: Metformin does not usually cause weight gain; it may even help with modest weight loss.
  • Myth: Metformin can be stopped once blood sugar is normal.
    Fact: Metformin controls blood sugar but does not cure diabetes. Stopping it without medical advice can cause blood sugar to rise again.
  • Myth: Metformin is safe for everyone with diabetes.
    Fact: Metformin is not suitable for people with severe kidney or liver disease, diabetic ketoacidosis, or those who drink excessive alcohol.

🔄 Alternative Options

Generic Alternatives

  • Metformin 500mg tablet

Brand Alternatives

  • Almetfor 500mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Almetfor 500mg tablet","active_ingredient":"Metformin 500mg","class":"Biguanide","primary_use":"Type 2 diabetes","route":"Oral"},{"medicine":"Metformin 850mg tablet","active_ingredient":"Metformin 850mg","class":"Biguanide","primary_use":"Type 2 diabetes","route":"Oral"},{"medicine":"Glimepiride 1mg tablet","active_ingredient":"Glimepiride 1mg","class":"Sulfonylurea","primary_use":"Type 2 diabetes","route":"Oral"}]

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