Glutamune DT 1000 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Difficulty breathing or swelling of face, lips, or throat
- Seizures
- Yellowing of skin or eyes
- Decreased urine output
- Confusion or unusual drowsiness
If experiencing severe symptoms, call emergency services immediately.
What is glutamune dt 1000 tablet used for?
This medicine contains L-Glutamine 1000 mg, an amino acid that supports gut health and immune function. It is used for short bowel syndrome, chemotherapy-induced mucositis, and sickle cell disease. Take it orally as prescribed, usually once or twice daily.
- Generic Name: L-Glutamine (1000mg)
- Manufacturer: Astaris lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 glutamune dt 1000 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एल-ग्लूटामाइन 1000 मिलीग्राम युक्त एक टैबलेट है, जो एक अमीनो एसिड है। यह आंतों के स्वास्थ्य और प्रतिरक्षा प्रणाली का समर्थन करती है। इसका उपयोग शॉर्ट बोवेल सिंड्रोम, कीमोथेरेपी से होने वाले म्यूकोसाइटिस, और सिकल सेल रोग में किया जाता है। यह आंतों की कोशिकाओं को ऊर्जा प्रदान करती है और ऊतकों की मरम्मत में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सूजन और दस्त शामिल हो सकते हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी प्रतिक्रिया, दौरे, या यकृत एंजाइम में वृद्धि हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित खुराक से अधिक न लें। यदि आपको यकृत रोग, गुर्दा रोग, या दौरे की समस्या है तो डॉक्टर को बताएं। इस दवा के साथ शराब का सेवन न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।
💊 glutamune dt 1000 tablet Uses & Benefits
[{"condition":"Short bowel syndrome","description":"This medicine helps improve nutrient absorption and intestinal adaptation in patients with short bowel syndrome by providing fuel to the remaining intestinal cells.","evidence":"Well-established"},{"condition":"Chemotherapy-induced mucositis","description":"This medicine may reduce the severity and duration of oral and gastrointestinal mucositis caused by chemotherapy or radiation therapy.","evidence":"Moderate"},{"condition":"Inflammatory bowel disease (IBD)","description":"This medicine may support gut barrier function and reduce inflammation in conditions like Crohn's disease and ulcerative colitis, though evidence is mixed.","evidence":"Limited"},{"condition":"Sickle cell disease","description":"This medicine may reduce the frequency of painful vaso-occlusive crises by improving hydration of red blood cells and reducing oxidative stress.","evidence":"Moderate"},{"condition":"Immune support","description":"This medicine provides fuel for immune cells and may enhance immune function in critically ill patients or those with compromised immunity.","evidence":"Limited"}]
Off-label uses: [{"condition":"Muscle recovery and athletic performance","description":"Some athletes use this medicine to support muscle recovery and reduce muscle soreness after intense exercise.","evidence":"Limited"},{"condition":"Irritable bowel syndrome (IBS)","description":"This medicine may help alleviate symptoms of IBS by supporting gut barrier function, but evidence is not robust.","evidence":"Limited"},{"condition":"Chemotherapy-induced peripheral neuropathy","description":"Preliminary studies suggest this medicine might reduce nerve pain caused by certain chemotherapy drugs.","evidence":"Limited"}]
Primary treatment for: Short bowel syndrome
Also treats: Chemotherapy-induced mucositis, Inflammatory bowel disease, Sickle cell disease
📋 Drug Information
| Generic Name(s) | L-Glutamine (1000mg) |
| Brand Name | glutamune dt 1000 tablet |
| Manufacturer | Astaris lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
L-Glutamine is a conditionally essential amino acid that serves as a primary energy source for enterocytes and lymphocytes. It is converted to glutamate, alpha-ketoglutarate, and other intermediates that fuel the citric acid cycle and support nucleotide synthesis. By providing these substrates, this medicine helps maintain the integrity of the intestinal mucosa, promotes cell proliferation and repair, and enhances immune cell function. It also acts as a precursor for glutathione, a major antioxidant, thereby reducing oxidative stress.
Mechanism Steps
💡 How to Take glutamune dt 1000 tablet
Strength: Immediate-release tablet, 1000 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1000 mg taken orally, often once or twice daily, depending on the condition being treated. For short bowel syndrome, doses up to 30 grams per day may be used under medical supervision. For chemotherapy-induced mucositis, 10-15 grams per day may be divided into 2-3 doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal and hepatic function. Consult a doctor for individualized dosing. |
| Renal Impairment | In patients with renal impairment, dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Doses up to 30 grams per day have been used in clinical settings under medical supervision. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of glutamune dt 1000 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Lactulose | Moderate | |
| Methotrexate | Major | |
| Phenytoin | Moderate | |
| Valproate | Moderate | |
| Furosemide | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Lactulose
- Chemotherapy agents (e.g., methotrexate)
⚡ Moderate Interactions
- Anticonvulsants (e.g., phenytoin, valproate)
- Diuretics
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage and may worsen side effects such as nausea and abdominal pain. It may also reduce the effectiveness of L-Glutamine in supporting gut health.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to L-Glutamine or any component of the formulation","Severe liver disease with hepatic encephalopathy","Severe kidney disease with ammonia accumulation","History of seizures (unless under close medical supervision)"]
⚠️ Warnings & Precautions
["Use with caution in patients with liver disease, kidney disease, or a history of seizures.","Do not exceed the recommended dose.","Avoid alcohol while taking this medicine.","Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children.","If you experience any allergic reaction, stop the medicine and seek medical help immediately."]
🤱 Lactation Safety
It is not known whether L-Glutamine is excreted in human breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it may lead to ammonia accumulation and neurological symptoms. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Inform your doctor if you have a history of liver disease, kidney disease, or seizures. Avoid alcohol while taking this medicine as it may increase the risk of side effects. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for longer than recommended without medical advice. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney or liver function and may require dose adjustments. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. The safety of L-Glutamine during pregnancy is not well established.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to support gut healing and nutrient absorption. Follow your surgeon's instructions regarding dosing and timing.
🦷 Dental Procedures
No specific precautions are needed for dental procedures. However, inform your dentist about all medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness, fatigue, or muscle weakness, avoid strenuous activities and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid these activities until you know how the medicine affects you.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or allergic reactions, stop immediately and seek medical attention. Your doctor will advise on whether to discontinue or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine is generally considered safe when taken as prescribed. However, prolonged high-dose use may lead to elevated liver enzymes or ammonia levels. Regular monitoring of liver and kidney function is recommended for patients on long-term therapy. Discontinue use if any adverse effects occur and consult your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing intake of glutamine-rich foods may support gut health, but may not be sufficient for therapeutic effects.
Evidence: LimitedProbiotics can complement glutamine in supporting gut health.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid exposure to extreme heat or moisture. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action varies depending on the condition. For gastrointestinal effects, it may take a few days to weeks. For sickle cell disease, it may take several weeks to months to notice a reduction in pain crises.
A: Inform your doctor about all medications you are taking, as L-Glutamine may interact with certain drugs like lactulose and chemotherapy agents.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor before use.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is a steroid.
Fact: This medicine contains L-Glutamine, an amino acid, not a steroid. - Myth: It can be taken without a prescription.
Fact: This medicine should be taken under medical supervision, especially for specific conditions. - Myth: It is a performance-enhancing drug.
Fact: This medicine is not a performance-enhancing drug; it is used for medical conditions.
🔄 Alternative Options
Generic Alternatives
- L-Glutamine 1000 mg tablet
Brand Alternatives
- Glutamune DT 1000 Tablet