glosmo syrup - Aluminium Hydroxide (250mg) + Magnesium (250mg) medicine

Accid-AMS Oral Suspension Sugar Free: Complete Medicine Guide

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🏭 Riasmo Lifesciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of acid-related disorders.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or stool
  • Severe abdominal pain
  • Difficulty breathing or swelling of face/lips/throat
  • Irregular heartbeat or palpitations
  • Muscle weakness or confusion
  • Decreased urine output
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is glosmo syrup used for?

This medicine is a sugar-free antacid suspension containing aluminium hydroxide and magnesium. It provides fast relief from heartburn, acid indigestion, and GERD symptoms by neutralizing stomach acid. It is taken orally, usually 10-20 mL after meals and at bedtime.

  • Generic Name: Aluminium Hydroxide (250mg) + Magnesium (250mg)
  • Manufacturer: Riasmo Lifesciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 glosmo syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एल्युमिनियम हाइड्रॉक्साइड और मैग्नीशियम का संयोजन है, जो पेट की अम्लता को कम करने में मदद करती है। इसका उपयोग सीने में जलन, एसिडिटी, गैस, और गैस्ट्रोएसोफेगल रिफ्लक्स डिजीज (GERD) के लक्षणों से राहत पाने के लिए किया जाता है। यह शुगर-फ्री है, इसलिए मधुमेह रोगी भी इसका उपयोग कर सकते हैं। यह दवा भोजन के बाद और सोने से पहले लेने की सलाह दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कब्ज, दस्त, और मुँह में चॉकी स्वाद शामिल हैं। कब्ज एल्युमिनियम के कारण हो सकती है, जबकि मैग्नीशियम से दस्त हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन गुर्दे की बीमारी वाले लोगों में मैग्नीशियम का स्तर बढ़ सकता है। यदि आपको गंभीर पेट दर्द, मल में खून, या एलर्जी के लक्षण दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। बोतल को अच्छी तरह हिलाएँ और मापने वाले कप से सही मात्रा लें। दो सप्ताह से अधिक समय तक बिना डॉक्टर की सलाह के न लें। गुर्दे की बीमारी वाले मरीज इसका सेवन न करें। अन्य दवाओं के साथ लेने से पहले डॉक्टर से परामर्श करें और कम से कम 2 घंटे का अंतराल रखें। गर्भवती और स्तनपान कराने वाली महिलाएँ डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 glosmo syrup Uses & Benefits

[{"condition":"Heartburn and acid indigestion","description":"Provides rapid relief by neutralizing excess stomach acid.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Helps reduce symptoms of acid reflux such as burning in the chest and throat.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Used as an adjunct to reduce pain and promote healing by lowering stomach acidity.","evidence":"Well-established"},{"condition":"Gastritis","description":"Soothes inflamed stomach lining by reducing acid irritation.","evidence":"Well-established"},{"condition":"Hyperphosphatemia","description":"Aluminium hydroxide can bind phosphate in the gut, reducing absorption; used in kidney disease under medical supervision.","evidence":"Well-established for aluminium component"}]

Off-label uses: [{"condition":"Prevention of stress ulcers in critically ill patients","description":"Sometimes used off-label in hospital settings to prevent stress-related gastrointestinal bleeding.","evidence":"Limited"},{"condition":"Reduction of urinary phosphate stones","description":"May be used off-label to reduce phosphate absorption in certain stone formers.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Peptic ulcer disease, Gastritis, Heartburn, Acid indigestion

📋 Drug Information

Generic Name(s)Aluminium Hydroxide (250mg) + Magnesium (250mg)
Brand Nameglosmo syrup
ManufacturerRiasmo Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a tightly closed container. Protect from direct sunlight and moisture. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine 20-60 minutes after meals and at bedtime for best effect.
2
Shake the bottle well before each use to ensure proper mixing.
3
Separate this medicine from other medications by at least 2 hours to avoid interactions.
4
Do not use for more than 2 weeks without consulting a doctor.
5
If you have kidney disease, avoid this medicine unless specifically prescribed.
6
Report any signs of severe constipation, diarrhea, or allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heartburn
This medicine is commonly used for this symptom.
Likely Use
Acid indigestion
This medicine helps neutralize excess acid.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
This medicine is not for headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAluminium hydroxide and magnesium are minimally absorbed from the gastrointestinal tract. Small amounts of aluminium and magnesium ions may be absorbed, but systemic absorption is generally low in individuals with normal kidney function.
DistributionAbsorbed aluminium and magnesium are distributed in small amounts to various tissues, but they do not undergo extensive systemic distribution under normal circumstances. In patients with kidney impairment, accumulation can occur.
Protein BindingNot established from the available information.
MetabolismAluminium and magnesium are not metabolized in the liver; they are excreted unchanged.
Half-LifeNot established from the available information.
ExcretionAbsorbed aluminium and magnesium are primarily excreted by the kidneys. Unabsorbed portions are excreted in the feces.
BioavailabilityNot established from the available information.
Onset of ActionRelief typically begins within minutes after oral administration.
Peak Plasma TimeNot applicable; the action is local in the stomach, and systemic absorption is minimal.
Duration of ActionThe effect lasts approximately 30 to 60 minutes when taken on an empty stomach, but may last longer if taken with food.

How It Works

This medicine works by directly neutralizing gastric acid through a chemical reaction. Aluminium hydroxide reacts with hydrochloric acid in the stomach to form aluminium chloride and water, while magnesium reacts with hydrochloric acid to form magnesium chloride and water. This reaction raises the pH of the stomach contents, reducing acidity and relieving symptoms of heartburn and indigestion. Additionally, aluminium hydroxide has a mild astringent effect and can bind to phosphate, while magnesium acts as a laxative to counteract the constipating effect of aluminium. The combination provides a balanced effect on bowel movements.

Mechanism Steps

1
Neutralization of gastric acid: Aluminium hydroxide and magnesium react with hydrochloric acid in the stomach to form salts and water, raising the pH.
2
Reduction of pepsin activity: By increasing gastric pH, this medicine reduces the activity of pepsin, an enzyme that can irritate the stomach lining.
3
Protection of mucosa: The reduction in acidity helps protect the esophageal and gastric mucosa from acid-induced damage.
4
Phosphate binding: Aluminium hydroxide binds dietary phosphate in the gut, reducing its absorption; this is used therapeutically in kidney disease.
5
Balanced bowel effect: Magnesium counteracts the constipating effect of aluminium by promoting bowel movements.

💡 How to Take glosmo syrup

Strength: Each 5 mL of oral suspension contains Aluminium Hydroxide 250 mg and Magnesium 250 mg.

1Shake the bottle well before each use.
2Measure the dose using the provided measuring cup or spoon.
3Take orally, preferably 20-60 minutes after meals and at bedtime.
4Do not take more than the recommended dose.
5If taking other medications, separate by at least 2 hours.

Dosage Information

Adult DosageThe usual adult dose is 10-20 mL of the suspension taken 3-4 times daily, preferably 20-60 minutes after meals and at bedtime, or as directed by a physician. The dose may be adjusted based on the severity of symptoms and individual response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the constipating effects of aluminium and the laxative effects of magnesium. Use with caution and monitor for electrolyte imbalances. Dose adjustment may be necessary based on kidney function.
Renal ImpairmentIn patients with renal impairment, aluminium and magnesium can accumulate. This medicine should be avoided or used with extreme caution under medical supervision. Dose reduction may be required.
Hepatic ImpairmentNo specific dosage adjustment is required for hepatic impairment, as the medicine is not metabolized by the liver.
Maximum Daily DoseThe maximum daily dose is not established from available information. Follow your doctor's prescription and do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take 20-60 minutes after meals
Food helps prolong the antacid effect.
At bedtime
Take before sleep if needed
Helps control nighttime acid reflux.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of glosmo syrup

✅ Common Side Effects

Constipation (Common (5-10%))
Increase fluid and fiber intake. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe.
Chalky taste (Common (5-10%))
Rinse mouth after taking. Usually not bothersome.
Nausea (Uncommon (1-5%))
Take with food to reduce nausea. Consult doctor if persistent.

🚨 Serious Side Effects

Severe constipation or bowel obstruction (Rare (<0.1%))
Seek immediate medical attention if you have severe abdominal pain, vomiting, or inability to pass stool.
Hypermagnesemia (high magnesium levels) (Rare (<0.1%))
More common in kidney disease. Seek medical help if you experience muscle weakness, confusion, or irregular heartbeat.
Aluminium toxicity (Rare (<0.1%))
Risk increases with kidney impairment. Symptoms include confusion, bone pain, and anemia. Seek medical attention.
Hypophosphatemia (low phosphate levels) (Rare (<0.1%))
May occur with prolonged use. Symptoms include weakness, fatigue, and bone pain. Consult doctor.

⚠️ Rare Side Effects

Allergic reactions such as rash, itching, or swelling
Seek immediate medical attention if you experience swelling of face, lips, or throat, or difficulty breathing.
Kidney stones
Report severe flank pain or blood in urine to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Ciprofloxacin Major
Iron supplements Major
Levothyroxine Major
Atenolol Moderate
Prednisolone Moderate
Digoxin Moderate
Aspirin Minor
Pseudoephedrine Minor
Sodium polystyrene sulfonate Moderate

🚨 Major Interactions

  • Tetracycline antibiotics (e.g., doxycycline)
  • Fluoroquinolone antibiotics (e.g., ciprofloxacin)
  • Iron supplements
  • Levothyroxine

⚡ Moderate Interactions

  • Beta-blockers (e.g., atenolol)
  • Corticosteroids (e.g., prednisolone)
  • Digoxin

🍷 Alcohol Interaction

Alcohol can increase stomach acid production and may worsen the condition being treated. It is advisable to avoid or limit alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe kidney disease or kidney failure","Allergy to aluminium hydroxide, magnesium, or any ingredient","Bowel obstruction or severe constipation","Hypophosphatemia (low phosphate levels)","Myasthenia gravis (magnesium may worsen muscle weakness)"]

⚠️ Warnings & Precautions

["Do not use for more than 2 weeks without medical advice.","Avoid in patients with kidney disease unless directed by a doctor.","May interfere with absorption of other medications; separate doses.","Use with caution in elderly patients due to increased risk of constipation and kidney issues.","Not recommended for children under 12 years without medical advice.","Do not take with large amounts of milk or dairy products to avoid milk-alkali syndrome."]

🤱 Lactation Safety

Aluminium and magnesium are minimally absorbed systemically, so amounts in breast milk are expected to be very low. However, consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose can cause severe diarrhea, abdominal pain, and electrolyte imbalances. In case of overdose, seek immediate medical attention. Treatment is supportive and may include rehydration and electrolyte monitoring.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor or as written on the label. Do not take more than the recommended dose or use it for longer than two weeks without consulting a healthcare professional. Shake the bottle well before each use to mix the ingredients evenly. Measure the dose with a proper measuring spoon or cup, not a household spoon. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. People with kidney disease should avoid this medicine unless specifically told otherwise by a doctor. This medicine can interact with other medications, so inform your doctor about all the medicines you are taking. Do not take this medicine at the same time as other drugs; wait at least two hours before or after. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to constipation and electrolyte imbalances. Use with caution and monitor kidney function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before use if you are planning pregnancy. Occasional use is generally considered safe, but medical advice is recommended.

🏥 Post-Surgery Considerations

Consult your surgeon before using this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

No specific precautions. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce pressure on the stomach.
🥗
Avoid lying down immediately after meals.
😴
Eat smaller, more frequent meals.
💧
Limit spicy, fatty, and acidic foods.
🧘
Avoid smoking and alcohol.
🌞
Elevate the head of your bed if you have nighttime reflux.

🏋️ Exercise Considerations

Avoid vigorous exercise immediately after eating, as it can worsen reflux. Light activities like walking after meals are beneficial.

🥗 Diet Recommendations

Include fiber-rich foods to prevent constipation.
Stay well hydrated.
Avoid excessive caffeine and carbonated drinks.
Limit high-fat and spicy foods.

💼 Impact on Daily Work & Life

This medicine does not usually affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid these activities until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if symptoms persist beyond 2 weeks, if you experience severe side effects, or if you have kidney disease. Do not stop prescribed medications without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to electrolyte imbalances, such as low phosphate levels, and accumulation of aluminium or magnesium in patients with kidney disease. It may also cause constipation or diarrhea. Regular monitoring of kidney function and electrolytes is advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can reduce acid reflux symptoms.

Evidence: Well-established
Weight loss

Losing excess weight can decrease abdominal pressure and reflux.

Evidence: Well-established
Elevating head of bed

Helps prevent nighttime acid reflux.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep a copy of your prescription in case of customs checks. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue your usual dosing schedule as closely as possible. For short trips, take enough supply for the duration.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with frequent heartburn
Ravi often experienced burning in his chest after meals. His doctor prescribed this medicine, and he started taking it after dinner and at bedtime. Within a week, his symptoms improved significantly. He also reduced his intake of spicy and oily foods.
💡 Lesson: Taking the antacid at the right time and making dietary changes can greatly improve heartburn symptoms.
👤 A 60-year-old diabetic patient with acid reflux
Mrs. Sharma needed an antacid but was worried about sugar content. Her doctor recommended this sugar-free suspension. She took it as directed and found relief without affecting her blood sugar levels.
💡 Lesson: Sugar-free antacids are a safe option for diabetic patients, but always consult your doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within minutes after taking it.

Q: Can I take it with other medicines?

A: It can interact with many medicines. Separate doses by at least 2 hours and consult your doctor.

Q: Is it safe for daily use?

A: It is safe for short-term use. Do not use for more than 2 weeks without medical advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for glosmo syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure ulcers permanently.
    Fact: This medicine only relieves symptoms by neutralizing acid; it does not cure the underlying cause of ulcers.
  • Myth: It is safe to take indefinitely without supervision.
    Fact: Long-term use can lead to electrolyte imbalances and other complications; it should be used short-term unless advised by a doctor.
  • Myth: It can be taken with all other medicines without any interaction.
    Fact: It can interact with many drugs, reducing their absorption; always separate doses by at least 2 hours.

🔄 Alternative Options

Generic Alternatives

  • Aluminium hydroxide + Magnesium suspension (various manufacturers)

Brand Alternatives

  • Accid-AMS Oral Suspension Sugar Free

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredient":"Aluminium hydroxide + Magnesium","onset":"Fast","duration":"30-60 minutes","sugar_free":"Yes"},{"medicine":"Calcium carbonate antacid","active_ingredient":"Calcium carbonate","onset":"Fast","duration":"30-60 minutes","sugar_free":"Varies"}]

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