Atsure 1gm Injection: Comprehensive Medicine Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fever above 38°C or chills
- Easy bruising or bleeding
- Shortness of breath or difficulty breathing
- Severe abdominal pain
- Yellowing of skin or eyes
- Decreased urine output
- Severe headache with vision changes
If experiencing severe symptoms, call emergency services immediately.
What is gemtero 1gm injection used for?
This medicine is a chemotherapy injection containing gemcitabine 1 gram, used to treat various cancers by inhibiting DNA synthesis in cancer cells. It is given intravenously by a healthcare professional.
- Generic Name: Gemcitabine (1gm)
- Manufacturer: Hetero Drugs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 gemtero 1gm injection के बारे में (Hindi Summary)
उपयोग: यह दवा जेमसिटाबिन 1 ग्राम इंजेक्शन है, जिसका उपयोग विभिन्न प्रकार के कैंसर जैसे फेफड़ों का कैंसर, अग्नाशय का कैंसर, मूत्राशय का कैंसर, स्तन कैंसर और डिम्बग्रंथि के कैंसर के इलाज के लिए किया जाता है। यह दवा कैंसर कोशिकाओं के विकास को रोकती है और उन्हें नष्ट करती है। यह दवा केवल एक योग्य चिकित्सक द्वारा अस्पताल या क्लिनिक में इंजेक्शन के माध्यम से दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, थकान, बुखार, दाने और फ्लू जैसे लक्षण शामिल हैं। गंभीर दुष्प्रभावों में अस्थि मज्जा का दमन, यकृत विषाक्तता, गुर्दे की विषाक्तता, फेफड़ों की विषाक्तता और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। किसी भी असामान्य लक्षण को तुरंत अपने डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल एक योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। इसे स्वयं न लें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। संक्रमण से बचने के लिए सावधानी बरतें। उपचार के दौरान और अंतिम खुराक के कम से कम 6 महीने बाद तक प्रभावी गर्भनिरोधक का उपयोग करें। जीवित टीके न लगवाएं। संक्रमण, रक्तस्राव या असामान्य थकान के किसी भी लक्षण की तुरंत रिपोर्ट करें।
💊 gemtero 1gm injection Uses & Benefits
[{"condition":"Non-small cell lung cancer","description":"Used in combination with other chemotherapy agents for first-line treatment of advanced non-small cell lung cancer.","evidence":"Well-established"},{"condition":"Pancreatic cancer","description":"Used as first-line treatment for locally advanced or metastatic pancreatic cancer, often in combination with other agents.","evidence":"Well-established"},{"condition":"Bladder cancer","description":"Used in combination with cisplatin for advanced or metastatic bladder cancer.","evidence":"Well-established"},{"condition":"Breast cancer","description":"Used in combination with paclitaxel for metastatic breast cancer after failure of prior chemotherapy.","evidence":"Well-established"},{"condition":"Ovarian cancer","description":"Used in combination with carboplatin for recurrent platinum-sensitive ovarian cancer.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Biliary tract cancer","description":"Sometimes used off-label in combination with cisplatin for advanced biliary tract cancer.","evidence":"Limited"},{"condition":"Soft tissue sarcoma","description":"Occasionally used off-label as a single agent or in combination for advanced soft tissue sarcoma.","evidence":"Limited"}]
Primary treatment for: Various cancers including non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer, and ovarian cancer.
Also treats: Biliary tract cancer, Soft tissue sarcoma
📋 Drug Information
| Generic Name(s) | Gemcitabine (1gm) |
| Brand Name | gemtero 1gm injection |
| Manufacturer | Hetero Drugs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store vials at 2°C to 8°C (refrigerate). Do not freeze. Protect from light. Once reconstituted, use immediately or store as directed by the pharmacist. |
| Shelf Life | Refer to the expiry date on the vial. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a nucleoside analogue that inhibits DNA synthesis. After entering cells, it is phosphorylated to active diphosphate and triphosphate forms. The diphosphate inhibits ribonucleotide reductase, reducing deoxynucleotide production for DNA synthesis. The triphosphate competes with deoxycytidine triphosphate for incorporation into DNA, leading to chain termination and cell death. This medicine is cell cycle specific, primarily affecting cells in the S phase.
Mechanism Steps
💡 How to Take gemtero 1gm injection
Strength: 1 gram per vial, powder for solution for injection
Dosage Information
| Adult Dosage | The dose of this medicine is individualized based on the type of cancer, stage, combination with other drugs, and patient factors such as body surface area, renal and hepatic function. Common regimens include 1000 mg/m² intravenously over 30 minutes once weekly for 3 weeks followed by 1 week rest, or other schedules. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects. Dose adjustments may be necessary based on renal and hepatic function. Individualize by a qualified clinician. |
| Renal Impairment | Dose adjustments may be needed in patients with renal impairment. Monitor kidney function closely. Individualize by a qualified clinician. |
| Hepatic Impairment | Dose adjustments may be needed in patients with hepatic impairment. Monitor liver function closely. Individualize by a qualified clinician. |
| Maximum Daily Dose | Not established from the available information. Dosing is individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of gemtero 1gm injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Cisplatin | Moderate | |
| Paclitaxel | Moderate | |
| Live vaccines | Major |
🚨 Major Interactions
- Warfarin
- Live vaccines
⚡ Moderate Interactions
- Cisplatin
- Paclitaxel
🍷 Alcohol Interaction
Avoid alcohol consumption while receiving this medicine, as it may increase the risk of liver toxicity and worsen side effects such as nausea and fatigue.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to gemcitabine or any component of the formulation","Severe liver impairment","Severe kidney impairment","Pregnancy","Breastfeeding"]
⚠️ Warnings & Precautions
["This medicine should be administered only by a qualified healthcare professional.","Bone marrow suppression may occur, leading to increased risk of infection and bleeding.","Liver and kidney function should be monitored regularly.","Avoid live vaccines during treatment.","Use effective contraception during treatment and for at least 6 months after the last dose.","Report any signs of infection, bleeding, or unusual fatigue immediately."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding should be discontinued during treatment and for at least 1 week after the last dose.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of overdose, discontinue treatment and provide supportive care. Monitor blood counts, liver and kidney function closely.
⏰ Missed Dose
This medicine is administered by a healthcare professional. If you miss an appointment for your dose, contact your doctor as soon as possible to reschedule. Do not attempt to self-administer.
Additional Safety Advice
This medicine must be administered only by a qualified healthcare professional in a clinical setting. Do not attempt to self-administer. Inform your doctor about all medications you are taking, including over-the-counter drugs and herbal supplements. Avoid close contact with people who have infections. Use effective contraception during treatment and for at least 6 months after the last dose. Do not receive live vaccines while on this medicine. Report any signs of infection, bleeding, or unusual fatigue promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as bone marrow suppression and fatigue. Dose adjustments may be necessary based on renal and hepatic function. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
This medicine can cause fetal harm. Women of childbearing potential should use effective contraception during treatment and for at least 6 months after the last dose. Men should also use contraception during treatment and for at least 3 months after the last dose. Consult your doctor if you are planning pregnancy.
🏥 Post-Surgery Considerations
This medicine may affect wound healing and increase the risk of bleeding. Inform your surgeon about your treatment. Your doctor will decide the timing of surgery in relation to your chemotherapy schedule.
🦷 Dental Procedures
Inform your dentist about your treatment with this medicine. You may be at increased risk of bleeding and infection. Your dentist may recommend postponing elective dental procedures until your blood counts recover.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise may be beneficial but should be tailored to your energy levels. Avoid strenuous activities if you feel fatigued or have low blood counts. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause fatigue, nausea, and other side effects that can affect your ability to work and perform daily activities. You may need to take time off during treatment. Avoid driving or operating machinery if you feel tired or dizzy.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your oncologist. Treatment duration is determined by your doctor based on your response and side effects. If you experience severe side effects, contact your doctor immediately; they will decide whether to adjust or stop treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to cumulative bone marrow suppression, increased risk of infections, and organ toxicity. Regular monitoring of blood counts, liver and kidney function is essential. Some patients may experience persistent fatigue. Discuss any long-term concerns with your oncologist.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Enroll in clinical trials for new cancer therapies.
Evidence: VariesFocus on symptom relief and quality of life.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Avoid live vaccines during treatment with this medicine. Inactivated vaccines may be given, but their effectiveness may be reduced. Consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store vials in refrigerator (2°C to 8°C)
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if the solution is discolored or contains particles
✅ DO
Keep out of reach of children
❌ DON'T
Do not store at room temperature for prolonged periods
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a refrigerated condition (2°C to 8°C) during travel. Use a cooler bag with ice packs. Inform airport security about your medication. Check customs regulations for carrying chemotherapy drugs across borders. Plan your travel around your treatment schedule to avoid missing doses.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects of this medicine are not immediate. It may take several weeks to months to see a response, depending on the type and stage of cancer.
A: No, this medicine must be administered by a healthcare professional in a clinical setting.
A: Avoid alcohol, grapefruit, and live vaccines. Also avoid close contact with people who have infections.
🤔 Common Patient Concerns
🔄 Substitutes for gemtero 1gm injection
View AllAlternative brands with exact same active ingredient:
-
gembin 1gm injectionBiochem Pharmaceutical Industries ₹2,660.12 41.3% CHEAPER
-
chemobine 1gm injectionCytogen Pharmaceuticals India Pvt Ltd ₹4,781.25 5.5% COSTLIER
-
gemwel 1gm injectionGetwell Pharmaceutical Pvt Ltd ₹5,160.00 13.9% COSTLIER
-
winogem 1gm injectionWockhardt Ltd ₹5,227.46 15.3% COSTLIER
-
gemcite 1gm injectionEli Lilly and Company India Pvt Ltd ₹5,235.00 15.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: This medicine must be administered by a healthcare professional in a clinical setting. - Myth: This medicine has no side effects.
Fact: This medicine can cause serious side effects and requires regular monitoring.
🔄 Alternative Options
Generic Alternatives
- Gemcitabine
Brand Alternatives
- Gemzar