Bencomet Plus 5mg/850mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Rapid breathing, muscle pain, extreme tiredness, or stomach pain (possible lactic acidosis)
- Severe hypoglycemia with confusion, seizures, or loss of consciousness
- Yellowing of skin or eyes, dark urine, or pale stools
- Severe abdominal pain radiating to the back (possible pancreatitis)
- Signs of severe allergic reaction such as rash, swelling of face or throat, or difficulty breathing
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is geben m forte 5mg/850mg tablet sr used for?
This medicine is a combination of glibenclamide and metformin used to treat type 2 diabetes. It lowers blood sugar by increasing insulin release and improving insulin sensitivity. It is taken orally with meals.
- Generic Name: Glibenclamide (5mg) + Metformin (850mg)
- Manufacturer: Shinto Organics (P) Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 geben m forte 5mg/850mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा ग्लिबेंक्लामाइड और मेटफॉर्मिन का संयोजन है, जिसका उपयोग टाइप 2 डायबिटीज में ब्लड शुगर को नियंत्रित करने के लिए किया जाता है। यह अग्न्याशय से इंसुलिन निकलने में मदद करती है और शरीर की इंसुलिन के प्रति संवेदनशीलता को बढ़ाती है। इसे भोजन के साथ लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट में असहजता, धातु जैसा स्वाद और हल्की हाइपोग्लाइसीमिया शामिल हैं। गंभीर दुष्प्रभावों में लैक्टिक एसिडोसिस, गंभीर हाइपोग्लाइसीमिया और पैन्क्रियाटाइटिस हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें ताकि पेट की परेशानी और ब्लड शुगर कम होने का खतरा कम हो। नियमित रूप से ब्लड शुगर की जांच करें। शराब से बचें क्योंकि इससे लैक्टिक एसिडोसिस और हाइपोग्लाइसीमिया का खतरा बढ़ सकता है। किडनी या लिवर की समस्या हो तो डॉक्टर को बताएं।
💊 geben m forte 5mg/850mg tablet sr Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"Used as second-line therapy when metformin alone or glibenclamide alone does not achieve adequate glycemic control.","evidence":"Well-established"},{"condition":"Type 2 diabetes with insulin resistance","description":"Combines insulin secretagogue and insulin sensitizer actions to improve both fasting and postprandial glucose.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Polycystic ovary syndrome (PCOS) with insulin resistance","description":"Metformin component may be used off-label, but the combination with glibenclamide is not standard for PCOS.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Obesity, Dyslipidemia, Hypertension
📋 Drug Information
| Generic Name(s) | Glibenclamide (5mg) + Metformin (850mg) |
| Brand Name | geben m forte 5mg/850mg tablet sr |
| Manufacturer | Shinto Organics (P) Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Glibenclamide binds to ATP-sensitive potassium channels on pancreatic beta cells, causing depolarization and insulin release. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and improves peripheral insulin sensitivity.
Mechanism Steps
💡 How to Take geben m forte 5mg/850mg tablet sr
Strength: Tablet: Glibenclamide 5 mg + Metformin 850 mg
Dosage Information
| Adult Dosage | The usual starting dose is one tablet taken once or twice daily with meals. The dose may be adjusted by your doctor based on blood sugar levels, kidney function, and tolerability. The maximum daily dose is generally 4 tablets (20 mg glibenclamide and 3400 mg metformin). Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients should start at the lower end of the dose range and be monitored closely for hypoglycemia and renal function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73 m²). In mild to moderate renal impairment, dose reduction and close monitoring are required. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in mild to moderate liver disease; contraindicated in severe liver disease. Dose adjustment and close monitoring are required. |
| Maximum Daily Dose | Maximum daily dose is 20 mg glibenclamide and 3400 mg metformin (4 tablets of 5 mg/850 mg). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of geben m forte 5mg/850mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Contrast media | Major | |
| Alcohol | Major | |
| Beta-blockers | Major | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| ACE inhibitors | Moderate | |
| NSAIDs | Moderate | |
| Antacids | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Contrast media (iodinated)
- Alcohol
- Beta-blockers
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Diuretics (thiazides, loop)
- Corticosteroids
- ACE inhibitors
- NSAIDs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it increases the risk of lactic acidosis and severe hypoglycemia. It can also worsen liver function and interfere with blood sugar control.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Risk of lactic acidosis with metformin, especially in renal impairment, liver disease, alcohol use, or acute illness.","Risk of hypoglycemia, particularly with skipped meals, alcohol, or strenuous exercise.","Temporary discontinuation may be needed before surgery or contrast imaging.","Elderly patients are at higher risk of hypoglycemia and lactic acidosis.","Regular monitoring of kidney and liver function is essential.","Avoid alcohol during treatment."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose can cause severe hypoglycemia and lactic acidosis. Seek emergency medical attention immediately. Treatment includes glucose administration, monitoring of blood glucose and electrolytes, and supportive care. Hemodialysis may be considered for metformin overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember with food. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine with meals to lower the chance of stomach upset and low blood sugar. Check your blood sugar regularly as advised by your doctor. Carry a fast-acting sugar source like glucose tablets or candy in case of hypoglycemia. Avoid alcohol because it can increase the risk of lactic acidosis and low blood sugar. Tell your doctor if you have kidney or liver problems, or if you are scheduled for surgery or a contrast dye procedure. Do not stop or change the dose without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia and lactic acidosis. Start with a lower dose and monitor kidney function regularly. Avoid alcohol and ensure adequate fluid intake.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine is generally not recommended during pregnancy; insulin is preferred. Your doctor will adjust your treatment plan.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily stopped before surgery due to the risk of lactic acidosis and hypoglycemia. Follow your doctor's instructions regarding fasting and medication adjustments.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. You may need to adjust your dose or meal timing around dental procedures. Monitor blood sugar closely.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Check your blood sugar before and after exercise, and carry a fast-acting sugar source. Avoid strenuous exercise if your blood sugar is very low or very high. Consult your doctor before starting a new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause hypoglycemia, which can affect your ability to drive or operate machinery. Be cautious until you know how it affects you. Take regular breaks and meals during work hours. Inform your employer about your condition if necessary.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well-controlled, your doctor may adjust or change your treatment. Always seek medical advice before stopping.
📅 Long-Term Use Effects
Long-term use requires regular monitoring of blood sugar, kidney function, liver function, and vitamin B12 levels. Prolonged use may increase the risk of hypoglycemia and lactic acidosis, especially in those with kidney or liver disease. Regular follow-up with your doctor is essential to adjust the dose and prevent complications.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are essential for managing type 2 diabetes and can reduce medication needs.
Evidence: Well-establishedDPP-4 inhibitors, SGLT2 inhibitors, or GLP-1 receptor agonists may be alternatives based on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, people with diabetes should stay up to date with recommended vaccinations, including influenza and pneumococcal vaccines. Consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If traveling across time zones, consult your doctor about adjusting the timing of doses. Keep a fast-acting sugar source handy in case of hypoglycemia. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few hours, but full effects on HbA1c may take 2-3 months of consistent use.
A: It depends on the severity of kidney disease. It is contraindicated in severe renal impairment. Consult your doctor for individualized advice.
A: Take 15 grams of fast-acting carbohydrate (e.g., glucose tablets, candy, or juice) and recheck your blood sugar in 15 minutes. If symptoms persist, seek medical help.
🤔 Common Patient Concerns
🔄 Substitutes for geben m forte 5mg/850mg tablet sr
View AllAlternative brands with exact same active ingredient:
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ree mef forte 5mg/850mg tabletSunre Healthcare ₹24.38 77.4% CHEAPER
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dilept 5mg/850mg tabletZenox Pharmaceuticals Pvt Ltd ₹29.90 72.3% CHEAPER
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clamet forte tabletEssweil Pharma ₹31.88 70.4% CHEAPER
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glibamet 5mg/850mg tabletRemedy Life Sciences India Pvt Ltd ₹37.50 65.2% CHEAPER
-
bencomet plus 5mg/850mg tabletSunniva Life Science ₹39.00 63.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps control blood sugar but does not cure diabetes. Lifestyle changes and ongoing medical care are essential. - Myth: You can stop taking this medicine once your sugar levels are normal.
Fact: Stopping suddenly can cause blood sugar to rise again. Always consult your doctor before making changes. - Myth: This medicine is safe for everyone with diabetes.
Fact: It is not suitable for people with type 1 diabetes, severe kidney or liver disease, or certain other conditions.
🔄 Alternative Options
Generic Alternatives
- Glibenclamide + Metformin 5mg/850mg tablet
Brand Alternatives
- Bencomet Plus 5mg/850mg Tablet