Flacid MPS Syrup - Aluminium Hydroxide (250mg) + Simethicone (50mg) medicine

Gastric Gel Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Medcliff Pharmaceuticals Pvt Ltd 📦 bottle of 200 ml Syrup 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of acid indigestion and flatulence.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain or distension
  • Difficulty breathing or swelling of face/throat
  • Persistent vomiting or inability to pass stool
  • Confusion, memory loss, or bone pain (possible aluminium toxicity)
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is Flacid MPS Syrup used for?

This medicine is a combination of Aluminium Hydroxide and Simethicone used to relieve acid indigestion, heartburn, and gas. It works by neutralizing stomach acid and reducing gas bubbles. It is taken orally after meals or as directed by a doctor.

  • Generic Name: Aluminium Hydroxide (250mg) + Simethicone (50mg)
  • Manufacturer: Medcliff Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Flacid MPS Syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एल्युमिनियम हाइड्रॉक्साइड और सिमेथिकोन का संयोजन है, जिसका उपयोग एसिडिटी, सीने में जलन, गैस और पेट फूलने की समस्या से राहत दिलाने के लिए किया जाता है। यह पेट में अतिरिक्त एसिड को बेअसर करती है और गैस के बुलबुले को छोटा करके बाहर निकालने में मदद करती है। इसे भोजन के बाद या डॉक्टर के निर्देशानुसार लिया जा सकता है।

साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित मानी जाती है, लेकिन कुछ लोगों को कब्ज, पेट में असहजता, दस्त या जी मिचलाना हो सकता है। लंबे समय तक अधिक मात्रा में लेने से फॉस्फेट की कमी और एल्युमिनियम विषाक्तता हो सकती है, खासकर गुर्दे की बीमारी वाले लोगों में। गंभीर एलर्जी या आंतों में रुकावट जैसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार या लेबल पर लिखे अनुसार ही लें। अन्य दवाओं के साथ लेने से पहले कम से कम 2 घंटे का अंतराल रखें। पर्याप्त पानी पिएं ताकि कब्ज न हो। गुर्दे की बीमारी, गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बिना सलाह के 2 सप्ताह से अधिक इसका सेवन न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 Flacid MPS Syrup Uses & Benefits

[{"condition":"Acid indigestion and heartburn","description":"Provides rapid neutralization of gastric acid, relieving burning discomfort in the chest and upper abdomen.","evidence":"Well-established"},{"condition":"Flatulence and bloating","description":"Simethicone reduces surface tension of gas bubbles, allowing them to disperse and be expelled more easily.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD) symptom relief","description":"Used as an adjunct for short-term relief of mild reflux symptoms; not a primary treatment for erosive esophagitis.","evidence":"Moderate"},{"condition":"Functional dyspepsia","description":"May help alleviate postprandial fullness, early satiety, and epigastric pain in some patients.","evidence":"Limited"},{"condition":"Peptic ulcer symptom relief","description":"Provides symptomatic relief of pain but does not heal ulcers; used alongside acid-suppressing therapy.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Prevention of stress ulcer bleeding","description":"Sometimes used in critically ill patients as part of stress ulcer prophylaxis, though proton pump inhibitors are preferred.","evidence":"Limited"},{"condition":"Reduction of gas prior to abdominal imaging","description":"Simethicone may be used off-label to reduce bowel gas before ultrasound or radiological procedures.","evidence":"Limited"}]

Primary treatment for: Acid indigestion

Also treats: Gastroesophageal reflux disease, Flatulence, Functional dyspepsia, Peptic ulcer disease

📋 Drug Information

Generic Name(s)Aluminium Hydroxide (250mg) + Simethicone (50mg)
Brand NameFlacid MPS Syrup
ManufacturerMedcliff Pharmaceuticals Pvt Ltd
Packaging / Formbottle of 200 ml Syrup (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine after meals and at bedtime for optimal acid control.
2
Maintain a 2-hour gap between this medicine and other medications to avoid absorption issues.
3
Increase fluid and fiber intake to prevent constipation.
4
Do not use for more than 2 weeks without medical advice.
5
Consult a doctor if you have kidney disease before using this medicine.
6
Report any signs of aluminium toxicity like confusion or bone pain immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn
This medicine is commonly used for this symptom.
Likely Use
✅
Bloating and gas
Simethicone helps relieve gas-related discomfort.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not intended for headache relief.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAluminium Hydroxide is minimally absorbed from the gastrointestinal tract; small amounts of aluminium ions may be absorbed, especially with high doses or renal impairment. Simethicone is not absorbed systemically and acts locally in the gut lumen.
DistributionAbsorbed aluminium is distributed mainly to bone, lungs, and brain, but systemic distribution is negligible in individuals with normal kidney function. Simethicone remains in the gastrointestinal tract and is excreted unchanged in feces.
Protein BindingNot established from the available information.
MetabolismAluminium Hydroxide is not metabolized; it is excreted unchanged. Simethicone is biologically inert and not metabolized.
Half-LifeNot established from the available information.
ExcretionAbsorbed aluminium is excreted primarily in urine. Unabsorbed aluminium and simethicone are excreted in feces.
BioavailabilityAluminium Hydroxide has low systemic bioavailability; Simethicone is not systemically absorbed.
Onset of ActionAntacid effect begins within minutes after oral administration. Simethicone's defoaming effect may take slightly longer but is also relatively rapid.
Peak Plasma TimeNot applicable for locally acting agents; systemic absorption of aluminium is minimal and variable.
Duration of ActionAcid-neutralizing effect lasts approximately 30 to 60 minutes when taken on an empty stomach, and up to 3 hours when taken after a meal. Simethicone's effect lasts until gas is expelled.

How It Works

This medicine combines two agents with complementary actions. Aluminium Hydroxide is a non-systemic antacid that neutralizes gastric acid by chemical reaction, forming aluminium chloride and water, thereby raising gastric pH. Simethicone is a silicone-based surfactant that lowers the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce into larger bubbles that are more easily eliminated. Together, they provide symptomatic relief from acid-related discomfort and trapped gas.

Mechanism Steps

1
Acid neutralization: Aluminium Hydroxide reacts with hydrochloric acid in the stomach to form aluminium chloride and water, raising the pH.
2
Pepsin inhibition: Elevated gastric pH reduces the activity of pepsin, an enzyme that can irritate the stomach lining.
3
Gas bubble coalescence: Simethicone lowers surface tension of gas bubbles, causing them to merge into larger bubbles.
4
Gas expulsion: Larger gas bubbles are more easily propelled through the gastrointestinal tract and expelled via belching or flatulence.

💡 How to Take Flacid MPS Syrup

Strength: Each tablet contains Aluminium Hydroxide 250 mg and Simethicone 50 mg.

1Swallow the tablet whole with a glass of water.
2Take after meals or as directed by your doctor.
3Do not crush or chew the tablet unless instructed.
4Maintain a gap of at least 2 hours from other medications.
5Follow the prescribed schedule consistently.

Dosage Information

Adult DosageThe usual adult dose is one to two tablets taken orally, preferably after meals and at bedtime, or as directed by a physician. The dose may be repeated as needed, but do not exceed the maximum daily dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the constipating effects of aluminium hydroxide. Use with caution and monitor for bowel irregularities. Dose adjustment may be necessary based on renal function.
Renal ImpairmentUse with caution in patients with renal impairment. Aluminium hydroxide may accumulate, leading to toxicity. Consult a nephrologist for dose adjustments. Simethicone is considered safe.
Hepatic ImpairmentNo specific dosage adjustments are required for hepatic impairment, as aluminium hydroxide is not metabolized by the liver.
Maximum Daily DoseThe maximum recommended daily dose is 4 tablets in 24 hours, but this may vary based on clinical judgment. Do not exceed without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take after meals
Food buffers the effect and prolongs acid neutralization.
Dairy products
Consume in moderation
Excessive dairy with aluminium antacids may increase aluminium absorption.
Alcohol
Avoid
Alcohol can worsen acidity and stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Flacid MPS Syrup

✅ Common Side Effects

Constipation (Common (5-10%))
Increase dietary fiber and fluid intake. Consult a doctor if constipation persists beyond a few days.
Abdominal discomfort (Uncommon (1-5%))
Usually transient. Take with food to minimize. Consult a doctor if severe or persistent.
Diarrhea (Uncommon (1-5%))
Stay hydrated. If diarrhea is severe or bloody, seek medical attention.
Nausea (Uncommon (1-5%))
Take with a small snack. If nausea persists, consult a doctor.

🚨 Serious Side Effects

Aluminium toxicity (encephalopathy, osteomalacia) (Rare (<0.1%))
Seek immediate medical attention if you experience confusion, memory loss, bone pain, or muscle weakness, especially if you have kidney disease.
Hypophosphatemia (Rare (<0.1%))
Report muscle weakness, fatigue, or bone pain. Blood tests may be needed.
Fecal impaction or bowel obstruction (Rare (<0.1%))
Seek immediate care if you have severe abdominal pain, vomiting, or inability to pass stool.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you develop rash, swelling of face/throat, or difficulty breathing.

⚠️ Rare Side Effects

Hypercalcemia
Report excessive thirst, frequent urination, or confusion.
Nephrolithiasis
Seek medical attention for severe flank pain or blood in urine.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Tetracycline Major
Levothyroxine Major
Iron salts Moderate
Propranolol Moderate
Digoxin Moderate
Phenytoin Moderate
Aspirin Minor
Benzodiazepines Minor
Corticosteroids Moderate

🚨 Major Interactions

  • Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
  • Tetracycline antibiotics
  • Levothyroxine
  • Iron salts

⚡ Moderate Interactions

  • Beta-blockers (e.g., propranolol, atenolol)
  • Corticosteroids (oral)
  • Digoxin
  • Phenytoin

🍷 Alcohol Interaction

Alcohol can irritate the stomach lining and worsen acid-related symptoms. It is advisable to avoid or limit alcohol while taking this medicine, as it may counteract the therapeutic effect and increase the risk of gastrointestinal irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to aluminium hydroxide, simethicone, or any component of the formulation","Severe renal impairment or chronic kidney disease without medical supervision","Suspected or confirmed gastrointestinal obstruction","Hypophosphatemia","Use in children under 12 years without medical advice"]

⚠️ Warnings & Precautions

["Do not use for more than 2 weeks without consulting a doctor.","Avoid taking other medications within 2 hours of this product.","Use with caution in elderly patients and those with renal impairment.","May cause constipation; ensure adequate fluid and fiber intake.","Not recommended for patients on a low-phosphate diet.","Consult a doctor if symptoms persist or worsen.","Keep out of reach of children."]

🤱 Lactation Safety

Aluminium hydroxide and simethicone are not known to be excreted in breast milk in significant amounts. They are considered compatible with breastfeeding, but nursing mothers should consult a doctor before use.

💊 Overdose Management

Overdose may cause severe constipation, abdominal pain, or electrolyte imbalances. In case of suspected overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal is not effective. Monitor electrolytes and renal function. In severe cases, especially with renal impairment, aluminium toxicity may require chelation therapy.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed or as directed on the label. Do not exceed the recommended dose or duration without consulting a doctor. Shake the suspension well if using a liquid form; swallow tablets whole with water. Take this medicine with or after meals for best effect. Maintain adequate hydration to help prevent constipation. Avoid taking other medicines within 2 hours of this product, as it can reduce their absorption. Inform your doctor if you have kidney disease, are on a low-phosphate diet, or are pregnant or breastfeeding. Do not use for more than 2 weeks unless advised by a clinician. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to constipation and electrolyte imbalances. Use with caution and monitor bowel habits and renal function. Dose adjustment may be needed.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It is generally considered safe, but individual assessment is recommended.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your surgeon. It may interact with other postoperative medications. Inform your surgeon about all medicines you are taking.

🦷 Dental Procedures

No specific precautions are required for dental procedures. However, inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Eat smaller, more frequent meals to reduce acid production.
🥗
Avoid spicy, fatty, and acidic foods that trigger heartburn.
😴
Maintain a healthy weight to reduce abdominal pressure.
💧
Do not lie down immediately after eating; wait at least 2 hours.
🧘
Elevate the head of your bed if you have nighttime reflux.
🌞
Quit smoking and limit alcohol consumption.

🏋️ Exercise Considerations

Moderate exercise is generally safe while taking this medicine. However, avoid vigorous exercise immediately after meals to prevent reflux. Stay hydrated during workouts.

🥗 Diet Recommendations

Include fiber-rich foods like fruits, vegetables, and whole grains.
Avoid caffeine, chocolate, and mint, which can relax the lower esophageal sphincter.
Limit high-fat and fried foods.
Stay well hydrated with water.
Consider smaller, more frequent meals.

💼 Impact on Daily Work & Life

This medicine does not usually affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness (rare), avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult a doctor if symptoms persist beyond 2 weeks, worsen, or if you experience severe side effects. Do not stop prescribed therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to constipation, hypophosphatemia, and aluminium accumulation, especially in patients with renal impairment. Regular monitoring of serum phosphate and aluminium levels is advised for prolonged use. It is not recommended for continuous use beyond 2 weeks without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary and lifestyle modifications

Avoiding trigger foods, eating smaller meals, and losing weight can reduce acid reflux.

Evidence: Well-established
Herbal remedies (e.g., ginger, chamomile)

May soothe the stomach, but evidence is limited and they can interact with medications.

Evidence: Limited
Stress reduction techniques

Yoga, meditation, and deep breathing can help reduce stress-related acidity.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions between this medicine and vaccines. You can receive vaccinations while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription if available. Store at room temperature and protect from moisture. When traveling across time zones, continue your regular dosing schedule as closely as possible. If you are flying, keep it in your carry-on luggage. Check customs regulations for carrying medications into other countries.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old software engineer with frequent acidity after late-night meals.
He started taking this medicine after dinner and at bedtime as prescribed. Within a few days, his heartburn and bloating reduced significantly. He also improved his diet and avoided late-night eating.
💡 Lesson: Taking the medicine as directed along with lifestyle changes provides better symptom control.
👤 A 60-year-old woman with chronic kidney disease and occasional indigestion.
She was advised to use this medicine sparingly due to her kidney condition. Her doctor monitored her aluminium levels and recommended a shorter duration. She experienced relief without complications.
💡 Lesson: Patients with kidney disease must use this medicine under strict medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within minutes after oral administration, providing rapid relief from acid symptoms.

Q: Can I take it with other medicines?

A: It can interact with many drugs. Maintain a gap of at least 2 hours between this medicine and other medications.

Q: Is it safe during pregnancy?

A: It is generally considered safe, but consult your doctor before use.

Q: What are the common side effects?

A: Constipation is the most common side effect. Others include abdominal discomfort and nausea.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Flacid MPS Syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure ulcers.
    Fact: This medicine only relieves symptoms; it does not heal ulcers. Ulcers require specific treatment.
  • Myth: It is safe to take indefinitely.
    Fact: Prolonged use can cause constipation, hypophosphatemia, and aluminium toxicity, especially in kidney disease.
  • Myth: It can be taken with all other medicines.
    Fact: It can interact with many drugs, reducing their absorption. Always separate by 2 hours.

🔄 Alternative Options

Generic Alternatives

  • Aluminium Hydroxide + Simethicone tablets
  • Aluminium Hydroxide + Simethicone suspension

📊 Comparison with Similar Medicines

[{"medicine":"Aluminium Hydroxide + Simethicone","composition":"Aluminium Hydroxide 250mg + Simethicone 50mg","onset":"Rapid","duration":"Short","main_use":"Acid indigestion, flatulence"},{"medicine":"Magnesium Hydroxide + Simethicone","composition":"Magnesium Hydroxide 400mg + Simethicone 40mg","onset":"Rapid","duration":"Short","main_use":"Acid indigestion, flatulence"},{"medicine":"Calcium Carbonate + Simethicone","composition":"Calcium Carbonate 500mg + Simethicone 40mg","onset":"Rapid","duration":"Short","main_use":"Acid indigestion, flatulence"}]

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