Febutaz 80 Tablet: Complete Medicine Guide for Gout and High Uric Acid
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes (jaundice)
- Dark urine or pale stools
- Severe abdominal pain
- Chest pain or shortness of breath
- Sudden weakness or numbness on one side of the body
- Swelling of face, lips, or throat
- Severe skin rash with blisters or peeling
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is febutax 80 tablet used for?
This medicine is a prescription tablet containing Febuxostat 80 mg. It is used to lower high uric acid levels in adults with gout. It works by blocking an enzyme called xanthine oxidase, which reduces uric acid production. It is not a painkiller and should not be used for acute gout attacks. Take it exactly as prescribed by your doctor.
- Generic Name: Febuxostat (80mg)
- Manufacturer: Leeford Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 febutax 80 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फेबुक्सोस्टेट 80 मिलीग्राम की एक प्रिस्क्रिप्शन टैबलेट है। इसका उपयोग गाउट (गठिया) वाले वयस्कों में यूरिक एसिड के उच्च स्तर को कम करने के लिए किया जाता है। यह ज़ैंथिन ऑक्सीडेज़ एंजाइम को रोककर काम करती है, जिससे शरीर में यूरिक एसिड का उत्पादन कम होता है। यह दर्द निवारक दवा नहीं है और तीव्र गाउट हमले के इलाज के लिए नहीं है। यह भविष्य में गाउट के दौरों को रोकने और जोड़ों में यूरिक एसिड के जमाव को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, दस्त और हल्के दाने शामिल हैं। कुछ लोगों को जोड़ों में दर्द या सूजन हो सकती है। गंभीर लेकिन दुर्लभ दुष्प्रभावों में गंभीर यकृत की क्षति, दिल का दौरा या स्ट्रोक, और गंभीर एलर्जी प्रतिक्रियाएं शामिल हैं। यदि आपको आंखों या त्वचा का पीलापन, गहरे रंग का मूत्र, गंभीर पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, या चेहरे, होंठ या गले में सूजन दिखे, तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। खुराक बदलें या दवा बंद करने से पहले डॉक्टर से सलाह लें। टैबलेट को पानी के साथ पूरा निगलें। इसे भोजन के साथ या बिना भी लिया जा सकता है, लेकिन भोजन के बाद लेने से पेट की परेशानी कम हो सकती है। इस दवा के साथ शराब का सेवन न करें। दिन भर पर्याप्त पानी पिएं। नियमित रूप से यूरिक एसिड, यकृत और हृदय की जांच कराएं। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो डॉक्टर से सलाह लें। यह दवा बच्चों के लिए नहीं है।
💊 febutax 80 tablet Uses & Benefits
[{"condition":"Chronic hyperuricemia in gout","description":"This medicine is used to lower high blood uric acid levels in adults with gout, helping to prevent future gout attacks and reduce uric acid deposits in joints and tissues.","evidence":"Well-established"},{"condition":"Prevention of gout flares","description":"When used regularly, this medicine reduces the frequency of acute gout attacks by keeping uric acid levels below the saturation point.","evidence":"Well-established"},{"condition":"Tumor lysis syndrome (prevention)","description":"In some patients receiving chemotherapy, this medicine may be used off-label to prevent high uric acid levels caused by rapid breakdown of cancer cells.","evidence":"Limited"}]
Off-label uses: [{"condition":"Tumor lysis syndrome","description":"Sometimes prescribed off-label to prevent or treat hyperuricemia associated with tumor lysis syndrome in patients with certain cancers.","evidence":"Limited"},{"condition":"Uric acid nephrolithiasis","description":"May be used off-label to reduce uric acid stone formation in patients with recurrent uric acid kidney stones.","evidence":"Limited"}]
Primary treatment for: Gout
Also treats: Hyperuricemia, Tumor lysis syndrome (prevention)
📋 Drug Information
| Generic Name(s) | Febuxostat (80mg) |
| Brand Name | febutax 80 tablet |
| Manufacturer | Leeford Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Xanthine oxidase Inhibitors-gout |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Store in the original container. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the enzyme xanthine oxidase. Xanthine oxidase is responsible for converting hypoxanthine to xanthine and then to uric acid. By blocking this enzyme, this medicine reduces the production of uric acid in the body. This leads to lower blood uric acid levels, which helps prevent the formation and deposition of uric acid crystals in joints and other tissues. Unlike some other uric-acid-lowering medicines, this medicine is a non-purine selective inhibitor, which means it does not interfere with other purine pathways as much.
Mechanism Steps
💡 How to Take febutax 80 tablet
Strength: Febuxostat 80 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 80 mg taken orally once daily, with or without food. For patients with mild to moderate renal impairment, no dose adjustment is needed. For patients with severe renal impairment, the dose may be reduced to 40 mg once daily. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No dose adjustment is required based on age alone. However, elderly patients may be more sensitive to the effects of this medicine, especially regarding cardiovascular and liver function. Regular monitoring is advised. The dose must be individualized by a qualified clinician. |
| Renal Impairment | For patients with mild to moderate renal impairment (creatinine clearance 30-89 mL/min), no dose adjustment is required. For patients with severe renal impairment (creatinine clearance less than 30 mL/min), the recommended dose is 40 mg once daily. Use with caution and monitor renal function regularly. |
| Hepatic Impairment | No dose adjustment is required for patients with mild to moderate hepatic impairment. This medicine is contraindicated in patients with severe hepatic impairment. Monitor liver function tests regularly. |
| Maximum Daily Dose | 80 mg per day. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of febutax 80 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Azathioprine | Major | |
| Mercaptopurine | Major | |
| Theophylline | Major | |
| Warfarin | Moderate | |
| NSAIDs | Moderate | |
| Thiazide diuretics | Moderate | |
| Antacids (Al/Mg) | Minor |
🚨 Major Interactions
- Azathioprine
- Mercaptopurine
- Theophylline
⚡ Moderate Interactions
- Warfarin
- NSAIDs
- Thiazide diuretics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol, especially beer, can increase uric acid levels and may trigger gout attacks. It also puts extra strain on the liver, which is already processing this medicine. If you drink alcohol, talk to your doctor about safe limits.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to febuxostat or any component of the formulation","Concomitant use with azathioprine","Concomitant use with mercaptopurine","Severe hepatic impairment","Pregnancy (unless clearly necessary)","Breastfeeding"]
⚠️ Warnings & Precautions
["Cardiovascular risk: This medicine may increase the risk of heart attack and stroke. Monitor patients with cardiovascular disease.","Liver injury: May cause severe liver damage. Monitor liver function tests.","Gout flares: May trigger gout attacks when starting treatment. Prophylactic treatment with NSAIDs or colchicine may be prescribed.","Hypersensitivity reactions: Severe allergic reactions have been reported. Discontinue if suspected.","Renal impairment: Use with caution in patients with severe renal impairment.","Secondary hyperuricemia: Not recommended for asymptomatic hyperuricemia.","Not for acute gout: This medicine is not effective for treating an acute gout attack."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in breastfed infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
There is limited information on overdose with this medicine. In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor vital signs and provide appropriate care. Dialysis is not expected to be effective in removing this medicine from the body.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Swallow the tablet whole with a glass of water. You may take it with or without food, but taking it after a meal may reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase uric acid levels and put extra strain on your liver. Drink plenty of water throughout the day to help flush out uric acid. Keep all follow-up appointments and get regular blood tests to check your uric acid levels, liver function, and heart health. Inform your doctor if you have a history of heart disease, stroke, or liver problems. Do not take this medicine if you are pregnant or planning to become pregnant without consulting your doctor. This medicine is not for children. Store it at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially regarding cardiovascular and liver function. Regular monitoring of liver and heart health is recommended. No dose adjustment is required based on age alone, but the dose should be individualized by a clinician.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy unless clearly necessary. If you are planning to become pregnant, consult your doctor before starting or continuing this medicine. Effective contraception should be used while taking this medicine. Discuss alternative treatments for gout if you are planning pregnancy.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to potential interactions with other medicines. Your doctor will advise you on when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific precautions, but it is important for your dentist to know your complete medication list. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine does not usually limit exercise, but if you are having a gout attack, rest the affected joint. Avoid high-impact activities that stress painful joints. Stay hydrated during exercise. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Do not drive or operate heavy machinery until you know how it affects you. It should not affect your ability to work, but if you have a physically demanding job, discuss with your doctor. Take it at the same time each day to fit your routine.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe liver problems, allergic reactions, or heart symptoms, seek immediate medical attention and your doctor may advise stopping the medicine. Otherwise, continue as prescribed to keep uric acid levels controlled.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing gout. However, it requires regular monitoring of uric acid levels, liver function, and cardiovascular health. Some patients may experience an increased risk of heart problems. It is important to keep all follow-up appointments and report any new symptoms to your doctor. Do not stop taking this medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another xanthine oxidase inhibitor that is often used first-line for gout. It may be an alternative if this medicine is not suitable.
Evidence: Well-establishedLimiting purine-rich foods, alcohol, and sugary drinks can help lower uric acid levels.
Evidence: Well-establishedLosing excess weight can reduce uric acid levels and gout attacks.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, continue taking your dose at the same time each day as much as possible. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering uric acid levels within 24 to 48 hours, but it may take 2 to 4 weeks to reach the full effect. Your doctor will monitor your uric acid levels to see if the dose is right for you.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, gout is a chronic condition. Stopping this medicine may cause uric acid levels to rise again and trigger gout attacks. Continue taking it as prescribed by your doctor.
A: This medicine has a boxed warning about an increased risk of cardiovascular death compared to another uric-acid-lowering medicine. If you have heart disease, your doctor will monitor you closely. Discuss any concerns with your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for febutax 80 tablet
View AllAlternative brands with exact same active ingredient:
-
febuxot 80 tabletZeelab Pharmacy Pvt Ltd ₹37.50 73.3% CHEAPER
-
StayHappi Febuxostat 80mg TabletSarvagunaushdhi Pvt Ltd ₹51.56 63.3% CHEAPER
-
febric 80mg tabletDomagk Smith Labs Pvt Ltd ₹79.69 43.3% CHEAPER
-
furitas 80mg tabletTas Med India Pvt Ltd ₹89.06 36.7% CHEAPER
-
urifix 80 mg tabletZuventus Healthcare Ltd ₹89.06 36.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to treat an acute gout attack.
Fact: This medicine is not a painkiller and does not relieve acute gout pain. It is used for long-term prevention of gout attacks by lowering uric acid levels. - Myth: You can stop taking this medicine once your uric acid level is normal.
Fact: Gout is a chronic condition. Stopping this medicine may cause uric acid levels to rise again and trigger gout attacks. Continue as prescribed by your doctor. - Myth: This medicine is safe for everyone.
Fact: This medicine is not for everyone. It is contraindicated in certain conditions such as severe liver disease and in people taking azathioprine or mercaptopurine. Always consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Febuxostat 80 mg tablet (generic)
Brand Alternatives
- Febutaz 80 Tablet