eyefen eye drop - Flurbiprofen (0.03% w/v) medicine

Aflur Eye Drop: Complete Guide to Uses, Side Effects, and Safety

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🏭 Solitaire Pharmacia Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 18, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for postoperative ocular inflammation.
Reviewed by
SaathiMed Expert Panel | Oct 18, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or sudden vision loss
  • Signs of allergic reaction such as swelling of face, lips, or throat
  • Severe redness or swelling that worsens
  • Blood in the eye or sudden floaters
  • Eye discharge that is thick or yellow-green
  • Increased sensitivity to light that does not improve

If experiencing severe symptoms, call emergency services immediately.

What is eyefen eye drop used for?

This medicine is an eye drop containing flurbiprofen, an NSAID used to reduce eye inflammation and pain after surgery. It works by blocking prostaglandins. Use as prescribed, usually one drop every 4-6 hours.

  • Generic Name: Flurbiprofen (0.03% w/v)
  • Manufacturer: Solitaire Pharmacia Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 eyefen eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों की सूजन और दर्द को कम करने के लिए इस्तेमाल की जाती है, खासकर आंखों की सर्जरी के बाद। यह प्रोस्टाग्लैंडिन नामक पदार्थ को रोककर काम करती है जो सूजन पैदा करता है। यह आंखों में लालिमा, दर्द और सूजन को कम करने में मदद करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में आंखों में जलन, खुजली, धुंधली दृष्टि और असुविधा शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें आंखों में तेज दर्द, कॉर्निया की समस्या या एलर्जी शामिल हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले और बाद में हाथ धोएं। ड्रॉपर की नोक को किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनने से पहले हटा दें और 15 मिनट बाद ही पहनें। यदि दृष्टि धुंधली हो तो वाहन न चलाएं। डॉक्टर की सलाह के बिना लंबे समय तक उपयोग न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 eyefen eye drop Uses & Benefits

[{"condition":"Postoperative ocular inflammation","description":"Used to reduce inflammation and pain after cataract surgery and other ocular procedures.","evidence":"Well-established"},{"condition":"Cystoid macular edema prophylaxis","description":"Helps prevent fluid accumulation in the macula following cataract surgery.","evidence":"Well-established"},{"condition":"Corneal abrasion pain","description":"Provides relief from pain and inflammation associated with corneal abrasions.","evidence":"Moderate"},{"condition":"Allergic conjunctivitis","description":"Reduces itching, redness, and swelling in allergic eye conditions.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Uveitis","description":"Sometimes used off-label to reduce inflammation in uveitis, though corticosteroids are preferred.","evidence":"Limited"},{"condition":"Scleritis","description":"May be used off-label for mild scleritis, but systemic treatment is usually needed.","evidence":"Limited"}]

Primary treatment for: Postoperative ocular inflammation

Also treats: Cystoid macular edema, Corneal abrasion, Allergic conjunctivitis

📋 Drug Information

Generic Name(s)Flurbiprofen (0.03% w/v)
Brand Nameeyefen eye drop
ManufacturerSolitaire Pharmacia Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)
Route of AdministrationOphthalmic
StorageStore at room temperature (15-30°C). Protect from light and freezing. Keep the bottle tightly closed when not in use.
Shelf LifeRefer to the expiry date on the packaging. Discard the bottle 4 weeks after opening, or as directed by your doctor.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this medicine to prevent infection.
2
Do not touch the dropper tip to your eye or any surface to avoid contamination.
3
If you wear contact lenses, remove them before use and wait at least 15 minutes before reinserting.
4
Use this medicine exactly as prescribed; do not increase the frequency or duration without consulting your doctor.
5
If you are using other eye drops, wait at least 5 minutes between applications to avoid washing out the medicine.
6
Report any persistent eye pain, redness, or vision changes to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Eye pain after surgery
This medicine is commonly prescribed for this.
Likely Use
✅
Eye redness and swelling
This medicine helps reduce inflammation.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption is minimal after topical ocular administration. Some absorption may occur through the nasolacrimal duct, but plasma levels are typically very low.
DistributionFlurbiprofen distributes into ocular tissues, including the cornea, aqueous humor, and iris-ciliary body. Protein binding in plasma is high (over 99%).
Protein BindingGreater than 99% bound to plasma proteins.
MetabolismFlurbiprofen is metabolized in the liver primarily by cytochrome P450 enzymes, mainly CYP2C9.
Half-LifeThe elimination half-life is approximately 3 to 6 hours.
ExcretionMetabolites are excreted mainly in the urine and to a lesser extent in feces.
BioavailabilitySystemic bioavailability after ocular administration is very low, estimated to be less than 5%.
Onset of ActionOnset of anti-inflammatory effect is typically within 30 minutes to 1 hour after instillation.
Peak Plasma TimePeak plasma concentrations are usually reached within 1 to 2 hours after topical ocular administration, but levels are very low.
Duration of ActionThe anti-inflammatory effect lasts for approximately 4 to 6 hours, requiring multiple daily doses.

How It Works

Flurbiprofen is a nonsteroidal anti-inflammatory drug that reversibly inhibits the cyclooxygenase enzymes (COX-1 and COX-2). In the eye, this inhibition reduces the synthesis of prostaglandins, which are key mediators of ocular inflammation, pain, and increased vascular permeability. By blocking prostaglandin production, flurbiprofen decreases signs and symptoms of inflammation such as redness, swelling, and pain.

Mechanism Steps

1
Penetration into ocular tissues: After instillation, flurbiprofen penetrates the cornea and reaches the aqueous humor and other ocular tissues.
2
Inhibition of cyclooxygenase: Flurbiprofen reversibly binds to and inhibits COX-1 and COX-2 enzymes in the eye.
3
Reduced prostaglandin synthesis: This inhibition decreases the production of prostaglandins, which are mediators of inflammation and pain.
4
Decreased inflammatory response: As a result, ocular inflammation, pain, and edema are reduced.

💡 How to Take eyefen eye drop

Strength: Ophthalmic solution containing flurbiprofen 0.03% w/v.

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a small pocket.
4Hold the dropper above your eye and squeeze one drop into the pocket.
5Close your eye gently and press the inner corner of your eye with your finger for 1-2 minutes to prevent the medicine from draining into your throat.
6Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose is one drop in the affected eye(s) every 4 to 6 hours as directed by your eye doctor. For postoperative use, it is typically started 24 hours before surgery and continued for 2 to 4 weeks after surgery. The exact dose and duration must be individualized by a qualified clinician based on the specific condition, severity, and patient response.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatric ophthalmologist.
Elderly DosageNo specific dose adjustment is required for elderly patients, but they should be monitored for increased sensitivity to side effects.
Renal ImpairmentNo dose adjustment is required for renal impairment when used as eye drops due to minimal systemic absorption.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment when used as eye drops due to minimal systemic absorption.
Maximum Daily DoseThe maximum daily dose is typically one drop in the affected eye(s) every 4 hours, not to exceed 6 doses per day. Follow your doctor's instructions.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of eyefen eye drop

✅ Common Side Effects

Transient stinging or burning (Common (5-10%))
Usually resolves within minutes. If persistent, consult your doctor.
Eye irritation (Common (5-10%))
May decrease with continued use. If it worsens, stop and consult your doctor.
Blurred vision (Common (5-10%))
Avoid driving until vision clears. If persistent, consult your doctor.

🚨 Serious Side Effects

Corneal thinning or perforation (Rare (<0.1%))
Seek immediate medical attention if you experience severe eye pain or vision loss.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you develop swelling of face, lips, or throat, or difficulty breathing.
Ocular bleeding (Rare (<0.1%))
Contact your doctor immediately if you notice blood in the eye or sudden vision changes.

⚠️ Rare Side Effects

Delayed wound healing
Inform your doctor if you notice slow healing after eye surgery.
Increased intraocular pressure
Your doctor may monitor eye pressure during treatment.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other topical NSAIDs Major
Corticosteroids (topical ocular) Major
Warfarin Moderate
Aspirin Moderate
Other eye drops Minor

🚨 Major Interactions

  • Other topical NSAIDs
  • Corticosteroids (topical ocular)

⚡ Moderate Interactions

  • Anticoagulants (e.g., warfarin)
  • Antiplatelet agents (e.g., aspirin)

🍷 Alcohol Interaction

No known interaction with alcohol when used as eye drops. However, alcohol may worsen inflammation and should be limited.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to flurbiprofen or other NSAIDs","Active ocular bleeding or bleeding disorders","Active herpes simplex keratitis","Use in patients with known corneal epithelial herpes simplex keratitis"]

⚠️ Warnings & Precautions

["For topical ophthalmic use only; not for injection or oral use.","Prolonged use may increase the risk of corneal adverse effects.","Do not use if the solution is discolored or contains particles.","Remove contact lenses before use and wait 15 minutes before reinserting.","Avoid touching the dropper tip to any surface to prevent contamination.","Use with caution in patients with a history of ocular bleeding.","Inform your doctor if you have diabetes, rheumatoid arthritis, or other conditions that may affect the eye."]

🤱 Lactation Safety

It is not known whether flurbiprofen passes into breast milk after ocular administration. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical nature. If accidental ingestion occurs, seek medical attention. Symptoms of systemic NSAID overdose may include nausea, vomiting, abdominal pain, and drowsiness.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Wash your hands before and after using this medicine. Do not touch the dropper tip to any surface to avoid contamination. Remove contact lenses before instillation and wait at least 15 minutes before reinserting them. Do not use this medicine if the solution changes color or contains particles. Avoid driving or operating machinery if your vision is temporarily blurred after use. Do not use this medicine for longer than prescribed, as prolonged use may increase the risk of corneal problems. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to corneal side effects. Use with caution and monitor for any signs of eye irritation or vision changes.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medicine during pregnancy has not been fully established.

🏥 Post-Surgery Considerations

This medicine is often prescribed after eye surgery to reduce inflammation and prevent complications. Use exactly as directed by your surgeon.

🦷 Dental Procedures

No specific precautions for dental procedures, but inform your dentist if you are using this medicine.

💚 Lifestyle Tips for Better Results

🏃
Avoid rubbing your eyes to prevent irritation.
🥗
Wear sunglasses outdoors to protect your eyes from bright light and wind.
😴
Maintain good hand hygiene to prevent eye infections.
💧
Follow a healthy diet rich in vitamins A, C, and E for eye health.
🧘
Get adequate sleep to support healing.

🏋️ Exercise Considerations

Avoid strenuous activities that may increase eye pressure or risk injury, especially after eye surgery. Consult your doctor before resuming exercise.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids like fish and flaxseed.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated to maintain tear production.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after application. Avoid driving or operating heavy machinery until your vision is clear. Most people can continue their normal activities with caution.

🛑 When to Stop This Medicine

Stop using this medicine when your doctor advises, usually after the prescribed course. Do not stop abruptly if you are using it for a chronic condition without consulting your doctor. If you experience serious side effects, stop and seek medical attention.

📅 Long-Term Use Effects

Prolonged use of this medicine may increase the risk of corneal thinning, delayed wound healing, and secondary infections. It is generally recommended for short-term use only. Regular eye examinations are advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cold compresses

Can help reduce eye swelling and discomfort.

Evidence: Well-established
Artificial tears

May soothe eye irritation, but do not treat inflammation.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, if you are scheduled for eye surgery, inform your doctor about any recent vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep a copy of your prescription with you. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue your regular dosing schedule as closely as possible. For air travel, keep the bottle in your carry-on bag to avoid freezing or losing it. Check customs regulations for carrying prescription eye drops.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man underwent cataract surgery and was prescribed this medicine.
He used the drops as directed, starting a day before surgery and continuing for three weeks. He experienced mild stinging initially but it subsided. His postoperative inflammation was well controlled, and he had no complications.
💡 Lesson: Adhering to the prescribed schedule and not skipping doses helps achieve optimal recovery after eye surgery.
👤 A 40-year-old woman with allergic conjunctivitis used this medicine for relief.
She found that her itching and redness decreased significantly within a few days. She was careful not to exceed the recommended dose and avoided wearing contact lenses during treatment.
💡 Lesson: This medicine can effectively relieve allergic eye symptoms when used appropriately and for short periods.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief within 30 minutes to 1 hour after applying the drops, but the full anti-inflammatory effect may take a few days.

Q: Can I use this medicine for dry eyes?

A: No, this medicine is not indicated for dry eyes. It is used for inflammation and pain after surgery or injury.

Q: Is this medicine a steroid?

A: No, it is a nonsteroidal anti-inflammatory drug (NSAID).

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for eyefen eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Aflur eye drop can be used for any eye infection.
    Fact: It is an anti-inflammatory, not an antibiotic. It does not treat infections.
  • Myth: More drops mean faster healing.
    Fact: Using more than prescribed can increase side effects without added benefit.

🔄 Alternative Options

Generic Alternatives

  • Flurbiprofen ophthalmic solution 0.03%

Brand Alternatives

  • Aflur eye drop

📊 Comparison with Similar Medicines

[{"medicine":"Flurbiprofen eye drops","class":"NSAID","primary_use":"Postoperative inflammation","frequency":"Every 4-6 hours"},{"medicine":"Ketorolac eye drops","class":"NSAID","primary_use":"Postoperative inflammation","frequency":"Four times daily"},{"medicine":"Diclofenac eye drops","class":"NSAID","primary_use":"Postoperative inflammation","frequency":"Four times daily"}]

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