Arblos-H 25mg/12.5mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Decreased urine output or swelling in the legs
- Irregular heartbeat or palpitations
- Severe muscle weakness or cramps
- Yellowing of the skin or eyes
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is etotan-h 25mg/12.5mg tablet used for?
This medicine is a combination of losartan and hydrochlorothiazide used to treat high blood pressure. It works by relaxing blood vessels and removing excess fluid from the body. It is taken once daily by mouth, usually with or without food, and must be prescribed by a doctor.
- Generic Name: Losartan (25mg) + Hydrochlorothiazide (12.5mg)
- Manufacturer: Solitaire Pharmacia Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 etotan-h 25mg/12.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। इसमें लोसार्टन और हाइड्रोक्लोरोथियाजाइड दो सक्रिय तत्व हैं, जो मिलकर रक्त वाहिकाओं को आराम देते हैं और शरीर से अतिरिक्त नमक और पानी को बाहर निकालते हैं। यह दवा आमतौर पर दिन में एक बार मुँह से ली जाती है। यह डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, और पेशाब में वृद्धि शामिल हैं। कुछ लोगों को मांसपेशियों में ऐंठन या जी मिचलाना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, या गंभीर त्वचा पर लाल चकत्ते दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे रक्तचाप फिर से बढ़ सकता है। पर्याप्त पानी पिएं और शराब से बचें। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट स्तर की जाँच कराते रहें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं।
💊 etotan-h 25mg/12.5mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults when a single medicine is not enough.
- It helps reduce the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Heart failure","description":"In some patients with heart failure, this combination may be used to reduce fluid overload and lower blood pressure, but it is not a first-line treatment for all heart failure patients.","evidence":"Moderate"},{"condition":"Diabetic nephropathy","description":"Losartan, one of the ingredients, can help protect the kidneys in people with diabetes and high blood pressure, especially when there is protein in the urine.","evidence":"Well-established for losartan component"}]
Off-label uses: [{"condition":"Left ventricular hypertrophy","description":"Sometimes used off-label to help reduce heart muscle thickening caused by high blood pressure, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Losartan has been studied off-label for preventing migraines, but this combination product is not typically used for that purpose.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Heart failure, Diabetic nephropathy
📋 Drug Information
| Generic Name(s) | Losartan (25mg) + Hydrochlorothiazide (12.5mg) |
| Brand Name | etotan-h 25mg/12.5mg tablet |
| Manufacturer | Solitaire Pharmacia Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from moisture and direct sunlight. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | The World Health Organization recommends thiazide diuretics and angiotensin receptor blockers as first-line options for treating high blood pressure in adults, but the exact combination and dose should be individualized. |
| ICMR Guideline | The Indian Council of Medical Research recommends a combination of antihypertensive medicines for patients whose blood pressure is not controlled with a single agent, with consideration of comorbidities and patient profile. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different but complementary ways of lowering blood pressure. Losartan blocks angiotensin II receptors, which prevents a powerful blood vessel-narrowing hormone from doing its work, so blood vessels relax and blood pressure falls. Hydrochlorothiazide increases the removal of sodium and water through the kidneys, which reduces blood volume and also helps blood vessels relax over time. The result is a more effective blood pressure reduction than either ingredient alone.
Mechanism Steps
💡 How to Take etotan-h 25mg/12.5mg tablet
Strength: Tablet containing losartan 25 mg and hydrochlorothiazide 12.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, with or without food. The dose may be adjusted by your doctor based on your blood pressure response and kidney function. Do not change the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure lowering effects of this medicine. Start with a lower dose and monitor closely for dizziness and falls. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with kidney problems, the dose may need to be reduced or the medicine may not be suitable. Regular monitoring of kidney function is required. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with liver disease, this medicine should be used with caution and may require dose adjustment. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of this strength, but your doctor may prescribe a different strength or frequency based on your condition. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of etotan-h 25mg/12.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Potassium supplements | Major | |
| Lithium | Major | |
| NSAIDs | Major | |
| Corticosteroids | Moderate | |
| Diabetes medicines | Moderate | |
| Cholestyramine | Moderate | |
| Antacids | Minor | |
| Digoxin | Minor |
🚨 Major Interactions
- Potassium supplements or potassium-sparing diuretics
- Lithium
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
⚡ Moderate Interactions
- Corticosteroids
- Diabetes medicines
- Cholestyramine and colestipol
🍷 Alcohol Interaction
Alcohol can increase the blood pressure lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is best to avoid alcohol or limit it strictly while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Severe kidney disease with no urine output","Severe liver disease","Allergy to losartan, hydrochlorothiazide, or sulfonamide-derived medicines","Concurrent use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["This medicine can cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.","Tell your doctor if you have a history of kidney or liver disease, diabetes, or gout.","This medicine may increase blood sugar levels; monitor if you have diabetes.","Avoid becoming dehydrated; drink enough fluids, especially during hot weather or exercise.","Inform your doctor if you are scheduled for surgery or dental work, as this medicine may need to be paused.","This medicine is not for use in children unless specifically prescribed by a pediatrician."]
🤱 Lactation Safety
It is not known whether losartan passes into breast milk in significant amounts. Hydrochlorothiazide passes into breast milk and may reduce milk production. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe low blood pressure, dizziness, fainting, and electrolyte imbalances. If you suspect an overdose, seek emergency medical help immediately. Treatment is supportive and may include intravenous fluids and monitoring of vital signs and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily, with or without food. Do not stop taking it suddenly without medical advice, because blood pressure may rise again. Keep well hydrated, especially in hot weather or during exercise, to reduce the risk of dizziness and low blood pressure. Avoid alcohol, as it can worsen dizziness and lower your blood pressure further. Have your blood pressure, kidney function, and electrolyte levels checked regularly as advised by your clinician. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding, because this medicine may not be safe in these situations. Do not take potassium supplements or salt substitutes containing potassium without asking your doctor first. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to dizziness, falls, and electrolyte imbalances. Start with a lower dose and monitor blood pressure and kidney function closely. Ensure adequate hydration.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine should be stopped and replaced with a safer alternative, as it can harm the developing baby.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be paused before surgery to prevent low blood pressure during the procedure. Follow your doctor's instructions.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine, as it may cause dry mouth or dizziness during dental procedures. Your dentist may recommend taking a break or adjusting the timing of your dose.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe and beneficial while taking this medicine, but start slowly and stay hydrated. Avoid sudden intense workouts, especially in hot weather, as they can cause dehydration and low blood pressure. If you feel dizzy or faint during exercise, stop and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work routine with regular monitoring.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects like allergic reactions, kidney problems, or severe dizziness, contact your doctor immediately. Your doctor may adjust the dose or switch to a different medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of kidney function, electrolyte levels, and blood pressure. It can increase blood sugar and uric acid levels, so diabetic and gout patients need careful monitoring. Most people tolerate it well for years with appropriate follow-up.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and may reduce the need for medicines.
Evidence: Well-establishedIf blood pressure is mildly elevated, a single medicine may be sufficient instead of a combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, inform your doctor about all medicines you take before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 2-4 weeks of regular use.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping can cause it to rise again.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.
A: No, this medicine is not recommended during pregnancy as it can harm the baby. Consult your doctor for safer alternatives.
🤔 Common Patient Concerns
🔄 Substitutes for etotan-h 25mg/12.5mg tablet
View AllAlternative brands with exact same active ingredient:
-
arblos-h 25mg/12.5mg tabletAqualife Pharmaceuticals ₹26.72 25% CHEAPER
-
nexlosar h 25mg/12.5mg tabletNexus Biotech ₹35.53 0.3% CHEAPER
-
losanorm 25-h tabletIpca Laboratories Ltd ₹64.73 81.7% COSTLIER
-
repace h 25 mg/12.5 mg tabletSun Pharmaceutical Industries Ltd ₹87.50 145.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping the medicine can cause it to rise again. Always consult your doctor before stopping. - Myth: This medicine damages the kidneys.
Fact: When used appropriately and monitored, this medicine can actually protect the kidneys, especially in people with diabetes. Regular monitoring is important. - Myth: You can take extra doses if you feel your blood pressure is high.
Fact: Taking extra doses can cause dangerously low blood pressure. Always follow your prescribed dose.
🔄 Alternative Options
Generic Alternatives
- Losartan + Hydrochlorothiazide generic tablets
Brand Alternatives
- Arblos-H 25mg/12.5mg Tablet