Agexa MS Oral Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Numbness or tingling in hands or feet
- Sudden joint pain or swelling
If experiencing severe symptoms, call emergency services immediately.
What is esnoflox ms oral suspension used for?
This medicine is a combination antibiotic containing Ofloxacin and Metronidazole, used to treat mixed bacterial and protozoal infections. It works by killing bacteria and parasites. It should only be taken as prescribed by a doctor.
- Generic Name: Ofloxacin (50mg) + Metronidazole (120mg)
- Manufacturer: Eveson Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 esnoflox ms oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन और मेट्रोनिडाजोल का संयोजन है, जिसका उपयोग विभिन्न जीवाणु और परजीवी संक्रमणों के इलाज के लिए किया जाता है। यह पेट, श्रोणि और आंतों के संक्रमण, बैक्टीरियल वेजिनोसिस, गियार्डिया और अमीबियासिस में प्रभावी है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में असहजता, सिरदर्द, चक्कर आना और मुँह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, दौरे और एलर्जी प्रतिक्रियाएँ हो सकती हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। उपयोग से पहले बोतल को अच्छी तरह हिलाएँ। सही मापने वाले कप या सिरिंज का उपयोग करें। दवा लेते समय और बाद में 48 घंटे तक शराब न लें। एंटासिड के साथ इस दवा को न लें, कम से कम 2 घंटे का अंतर रखें। यदि आपको चक्कर आते हैं तो वाहन न चलाएँ। गुर्दे या यकृत की समस्या हो तो डॉक्टर को बताएं।
💊 esnoflox ms oral suspension Uses & Benefits
[{"condition":"Intra-abdominal infections","description":"Used to treat mixed aerobic and anaerobic bacterial infections in the abdomen, such as peritonitis or abscesses.","evidence":"Well-established"},{"condition":"Pelvic inflammatory disease","description":"Effective against polymicrobial infections of the female reproductive tract when used as part of combination therapy.","evidence":"Well-established"},{"condition":"Bacterial vaginosis","description":"Metronidazole component targets anaerobic bacteria associated with bacterial vaginosis.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Metronidazole is effective against Giardia lamblia, though Ofloxacin is not typically used for this indication alone.","evidence":"Well-established"},{"condition":"Amebiasis","description":"Metronidazole is the primary agent for treating Entamoeba histolytica infections.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prophylaxis in colorectal surgery","description":"Sometimes used to prevent postoperative infections in colorectal surgery, though not FDA-approved for this specific use.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Intra-abdominal infections, Pelvic inflammatory disease, Bacterial vaginosis, Giardiasis, Amebiasis
📋 Drug Information
| Generic Name(s) | Ofloxacin (50mg) + Metronidazole (120mg) |
| Brand Name | esnoflox ms oral suspension |
| Manufacturer | Eveson Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. Keep the bottle tightly closed. Shake well before each use. |
| Shelf Life | Not established from the available information. Refer to the product packaging for the expiry date. |
| WHO Guideline | Not established from the available information. Consult current WHO guidelines for specific infections. |
| ICMR Guideline | Not established from the available information. Consult current ICMR guidelines for specific infections. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with distinct mechanisms. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Metronidazole enters anaerobic bacteria and protozoa, where its nitro group is reduced to reactive intermediates that damage DNA, causing strand breakage and inhibition of nucleic acid synthesis. The combination provides synergistic or additive coverage against mixed aerobic and anaerobic infections.
Mechanism Steps
💡 How to Take esnoflox ms oral suspension
Strength: Oral suspension containing Ofloxacin 50mg and Metronidazole 120mg per 5mL (or as specified by the manufacturer).
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on the specific infection, its severity, patient's age, weight, renal and hepatic function, and other factors. Typically, it is taken orally every 12 hours. Do not self-medicate. Follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Fluoroquinolones are generally not recommended for children under 18 years due to potential adverse effects on cartilage development. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects such as tendon rupture, CNS effects, and renal impairment. Dose adjustment may be needed based on renal function. Use with caution. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. Ofloxacin is primarily excreted by the kidneys. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with severe hepatic impairment. Metronidazole is metabolized in the liver. Consult your doctor. |
| Maximum Daily Dose | Not established from the available information. The maximum daily dose should be determined by a qualified clinician based on the indication and patient factors. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of esnoflox ms oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Antacids | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Caffeine | Moderate | |
| Cimetidine | Moderate | |
| Phenytoin | Moderate | |
| Sucralfate | Minor | |
| Iron supplements | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Antacids containing aluminum or magnesium
- Theophylline
- NSAIDs
⚡ Moderate Interactions
- Caffeine
- Cimetidine
- Phenytoin
🍷 Alcohol Interaction
Avoid alcohol completely while taking this medicine and for at least 48 hours after the last dose. Metronidazole can cause a disulfiram-like reaction with alcohol, leading to severe nausea, vomiting, flushing, headache, and rapid heartbeat. Alcohol may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Ofloxacin, Metronidazole, or any component of the formulation","Children under 18 years (for systemic fluoroquinolone use)","Pregnancy (unless clearly needed)","Breastfeeding (unless clearly needed)","History of tendon disorders with fluoroquinolones","Myasthenia gravis"]
⚠️ Warnings & Precautions
["Fluoroquinolones, including Ofloxacin, can cause disabling and potentially irreversible serious adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects. Reserve for infections with no alternative treatment options.","Metronidazole may cause a disulfiram-like reaction with alcohol. Avoid alcohol during and for 48 hours after therapy.","May cause dizziness and confusion. Avoid driving or operating machinery until you know how this medicine affects you.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. Monitor for superinfection.","Use with caution in patients with epilepsy or CNS disorders.","May enhance the effects of warfarin and other anticoagulants. Monitor INR closely.","Avoid concomitant use with antacids containing aluminum or magnesium, as they reduce Ofloxacin absorption."]
🤱 Lactation Safety
Not established from the available information. Both Ofloxacin and Metronidazole are excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, dizziness, and confusion. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis may be considered for Ofloxacin removal in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to incomplete treatment and antibiotic resistance. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring device to get the correct dose. Avoid alcohol completely while taking this medicine and for at least 48 hours after finishing, as it can cause a disulfiram-like reaction with Metronidazole. Inform your doctor about all other medications you are taking, especially blood thinners, antacids, and other antibiotics. Do not take antacids containing aluminum or magnesium within 2 hours of this medicine, as they can reduce absorption of Ofloxacin. If you have kidney or liver problems, your doctor may need to adjust the dose. Avoid driving or operating heavy machinery if you experience dizziness or confusion. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Keep this medicine out of reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment may be needed based on renal function. Monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
This medicine should be avoided during pregnancy and while trying to conceive unless clearly needed. Consult your doctor for alternative treatments if you are planning pregnancy.
🏥 Post-Surgery Considerations
This medicine may be used to treat or prevent postoperative infections. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures. No specific precautions are established.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as fluoroquinolones can increase the risk of tendon rupture. If you experience joint pain, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, confusion, or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to incomplete treatment and resistance. If you experience serious side effects, contact your doctor immediately; they may advise you to stop.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, superinfection, and rare but serious effects such as peripheral neuropathy, tendon rupture, and hepatotoxicity. Regular monitoring of renal and hepatic function may be required. Use only for the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea, but should be taken at least 2 hours apart from the antibiotic.
Evidence: LimitedSupports recovery from infection.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing while on antibiotics.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Always carry enough for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with food to reduce stomach upset. However, avoid taking it with dairy products or antacids as they can reduce absorption.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for esnoflox ms oral suspension
View AllAlternative brands with exact same active ingredient:
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macgyl o syrupTorque Pharmaceuticals Pvt Ltd ₹14.06 78.7% CHEAPER
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ofpil m suspensionPsychotropics India Ltd ₹15.58 76.4% CHEAPER
-
owin m 50mg/120mg syrupAlembic Pharmaceuticals Ltd ₹24.61 62.7% CHEAPER
-
otex m syrupBiocare Remedies ₹27.66 58.1% CHEAPER
-
urofin-m oral suspensionPositif Life sciences ₹30.00 54.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: This medicine is effective only against specific susceptible bacteria and protozoa. It is not effective against viral infections like the common cold or flu. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent recurrence and antibiotic resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol must be avoided completely during and for 48 hours after taking this medicine due to the risk of a disulfiram-like reaction.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin and Metronidazole oral suspension (generic)
Brand Alternatives
- Ofloxacin + Metronidazole suspension (various brands)