Azilta T 40 Tablet: Telmisartan + Azelnidipine for Hypertension
What is emdip t 40mg/8mg tablet used for?
This medicine is a prescription combination tablet containing Telmisartan 40 mg and Azelnidipine 8 mg, used to treat high blood pressure. It works by relaxing blood vessels through two different mechanisms, helping to lower blood pressure effectively when a single medicine is not enough.
- Generic Name: Telmisartan (40mg) + Azelnidipine (8mg)
- Manufacturer: Emcure Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 emdip t 40mg/8mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए उपयोग की जाती है। इसमें टेल्मिसार्टन और एज़ेलनिडिपिन दो सक्रिय तत्व होते हैं जो रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करते हैं।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, पैरों में सूजन और फ्लशिंग शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको बेहोशी, सांस लेने में कठिनाई, या चेहरे पर सूजन हो तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। रक्तचाप, गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट्स की नियमित निगरानी आवश्यक है। गर्भावस्था में इस दवा का उपयोग न करें। शराब का सेवन सीमित करें क्योंकि यह रक्तचाप को और कम कर सकता है।
💊 emdip t 40mg/8mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is indicated for the treatment of essential hypertension in adults.
- It is used when monotherapy with either Telmisartan or Azelnidipine alone does not provide adequate blood pressure control.
- The combination provides additive blood pressure reduction through complementary mechanisms."}]
Off-label uses: []
Primary treatment for: Hypertension
📋 Drug Information
| Generic Name(s) | Telmisartan (40mg) + Azelnidipine (8mg) |
| Brand Name | emdip t 40mg/8mg tablet |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature below 30°C, away from moisture and direct sunlight. Keep out of reach of children. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release, which reduces blood pressure and sodium retention. Azelnidipine inhibits the influx of calcium ions through L-type calcium channels in vascular smooth muscle cells, leading to relaxation of blood vessels and reduced peripheral resistance. The combined effect lowers both cardiac workload and vascular resistance.
Mechanism Steps
💡 How to Take emdip t 40mg/8mg tablet
Strength: 40 mg + 8 mg
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Telmisartan 40 mg + Azelnidipine 8 mg) once daily, preferably at the same time each day. Dose adjustments may be made by the prescribing physician based on blood pressure response and tolerability. This medicine should be taken exactly as prescribed. |
| Pediatric Dosage | Dose must be determined by a qualified clinician based on indication, age, weight, and renal/hepatic function. Safety and efficacy in pediatric patients are not established. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects. Dose should be individualized based on renal function and blood pressure response. Start with lower doses if appropriate. |
| Renal Impairment | No specific dose adjustment is established for mild to moderate renal impairment. In severe renal impairment or patients on dialysis, use with caution and monitor renal function and potassium levels. Dose must be determined by a qualified clinician. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. In severe hepatic impairment, the medicine is contraindicated. Dose must be determined by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Telmisartan 40 mg + Azelnidipine 8 mg) once daily. Higher doses should only be used under medical supervision. |
Dosage Timeline
⚠️ Side Effects of emdip t 40mg/8mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Minor | ||
| Minor | ||
| Minor | ||
| Minor |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone)
- Lithium
- NSAIDs (e.g., ibuprofen)
⚡ Moderate Interactions
- Other antihypertensives
- CYP3A4 inhibitors (e.g., ketoconazole)
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, increasing the risk of dizziness, fainting, and hypotension. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Telmisartan, Azelnidipine, or any component of the formulation.","Pregnancy (especially second and third trimesters).","Severe liver impairment or biliary obstruction.","Concomitant use with aliskiren in patients with diabetes mellitus.","Bilateral renal artery stenosis or unilateral renal artery stenosis in a single kidney."]
⚠️ Warnings & Precautions
[{"warning":"Hypotension in volume-depleted patients","reason":"Patients with volume or salt depletion may experience symptomatic hypotension.","action":"Correct volume depletion before starting treatment or start with lower dose under supervision."},{"warning":"Kidney function deterioration","reason":"Telmisartan can reduce glomerular filtration in patients with renal artery stenosis or chronic kidney disease.","action":"Monitor renal function and adjust dose as needed."},{"warning":"Hyperkalemia","reason":"Telmisartan can increase potassium levels.","action":"Monitor serum potassium, especially in patients with kidney disease or on potassium supplements."},{"warning":"Fetal toxicity","reason":"Angiotensin II receptor blockers can cause fetal harm or death when used in pregnancy.","action":"Discontinue as soon as pregnancy is detected. Use effective contraception."}]
🤱 Lactation Safety
Not established from the available information. It is not known whether Telmisartan or Azelnidipine is excreted in human breast milk. Breastfeeding should be avoided or the medicine should be discontinued, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose may cause severe hypotension, dizziness, and electrolyte disturbances. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs and electrolytes. Hemodialysis may be considered for Telmisartan overdose, but not for Azelnidipine due to high protein binding.
⏰ Missed Dose
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to catch up.
Additional Safety Advice
This medicine should be taken exactly as prescribed by a qualified healthcare professional. Do not change the dose or stop taking this medicine without medical advice. Regular monitoring of blood pressure, kidney function, and electrolytes is important during treatment. Avoid sudden discontinuation, as it may cause rebound hypertension. Patients with kidney artery narrowing, liver disease, or dehydration should inform their doctor before starting this medicine. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. Alcohol may enhance the blood pressure-lowering effect and should be avoided or limited. Pregnant women should not use this medicine, as it may harm the developing fetus.
🔄 Substitutes for emdip t 40mg/8mg tablet
View AllAlternative brands with exact same active ingredient:
-
azilta t 40 tabletRPG Life Sciences Ltd ₹142.00 4.6% COSTLIER
-
azusa t 8/40 tabletAjanta Pharma Ltd ₹142.50 5% COSTLIER
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telmed-az 40 tabletMedley Pharmaceuticals ₹142.50 5% COSTLIER
-
zeblong t 40mg/8mg tabletIpca Laboratories Ltd ₹158.60 16.8% COSTLIER
-
telma az 40mg/8mg tabletGlenmark Pharmaceuticals Ltd ₹174.37 28.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping the medicine can cause a dangerous rise in blood pressure. It should only be stopped under medical supervision. - Myth: This medicine can be taken without a prescription.
Fact: This is a prescription medicine and should only be taken under the guidance of a qualified healthcare professional. - Myth: This medicine causes kidney damage in everyone.
Fact: While this medicine can affect kidney function in some patients, it is often used to protect kidneys in certain conditions. Regular monitoring is important.