azusa t 8/40 tablet - Telmisartan (40mg) + Azelnidipine (8mg) medicine

Azovas T 40 Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

No reviews yet
🏭 Ajanta Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. This medicine can cause harm to the unborn baby, especially in the second and third trimesters. Use effective contraception and consult your doctor if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe dizziness or fainting
  • Irregular heartbeat or palpitations
  • Decreased urine output or swelling in legs
  • Yellowing of skin or eyes
  • Severe abdominal pain or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is azusa t 8/40 tablet used for?

This medicine is a combination of Telmisartan and Azelnidipine used to treat high blood pressure. It works by relaxing blood vessels and reducing peripheral resistance, thereby lowering blood pressure.

  • Generic Name: Telmisartan + Azelnidipine
  • Manufacturer: Ajanta Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 azusa t 8/40 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह टेल्मिसार्टन और एज़ेल्निडिपिन का संयोजन है, जो रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। यह उन रोगियों के लिए है जिनका रक्तचाप अकेले एक दवा से नियंत्रित नहीं होता। इस दवा को डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव जैसे बहुत कम रक्तचाप, पोटैशियम का बढ़ना, और गुर्दे की समस्या दुर्लभ हैं। यदि आपको चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई, या बेहोशी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही बंद करें। नियमित रूप से अपना रक्तचाप जांचते रहें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। पोटैशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो डॉक्टर को बताएं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से मिलें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 azusa t 8/40 tablet Uses & Benefits

[{"condition":"Essential Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Diabetic Nephropathy","description":"Sometimes prescribed off-label to slow kidney damage in diabetic patients with hypertension and proteinuria.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Cardiovascular risk reduction, Diabetic nephropathy

📋 Drug Information

Generic Name(s)Telmisartan + Azelnidipine
Brand NameAzovas T 40 Tablet
ManufacturerAjanta Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin II Receptor Blocker + Calcium Channel Blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly and keep a log to share with your doctor.
3
Avoid alcohol while taking this medicine as it can increase dizziness and low blood pressure.
4
Do not take potassium supplements or salt substitutes without consulting your doctor.
5
Inform your doctor if you experience swelling of ankles or feet, as the dose may need adjustment.
6
Use effective contraception while taking this medicine, as it can harm the unborn baby.
7
Do not stop this medicine abruptly; consult your doctor first.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood pressure
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTelmisartan is rapidly absorbed after oral administration, with peak plasma concentrations reached within 0.5 to 1.5 hours. Azelnidipine is also well absorbed orally, with peak levels at about 2 to 3 hours. Food does not significantly affect the absorption of either component.
DistributionBoth Telmisartan and Azelnidipine are highly bound to plasma proteins and distribute widely into tissues. Telmisartan has a large volume of distribution. Azelnidipine is highly lipophilic and accumulates in vascular smooth muscle.
Protein BindingTelmisartan is >99.5% bound to plasma proteins. Azelnidipine is approximately 90-95% bound to plasma proteins.
MetabolismTelmisartan undergoes minimal metabolism, primarily by glucuronidation. Azelnidipine is extensively metabolized in the liver, mainly by CYP3A4 enzymes.
Half-LifeTelmisartan has a terminal elimination half-life of approximately 24 hours. Azelnidipine has a half-life of about 10-15 hours.
ExcretionTelmisartan is excreted mainly in feces via bile, with less than 1% excreted unchanged in urine. Azelnidipine is excreted primarily in urine as metabolites.
BioavailabilityTelmisartan has an absolute bioavailability of about 42-58%. Azelnidipine has a bioavailability of approximately 30-40%.
Onset of ActionThe antihypertensive effect begins within 1-2 hours after oral administration, with maximum effect achieved within 2-4 weeks of continuous therapy.
Peak Plasma TimeTelmisartan: 0.5-1.5 hours; Azelnidipine: 2-3 hours.
Duration of ActionThe blood pressure-lowering effect lasts for approximately 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Azelnidipine inhibits the influx of calcium ions into vascular smooth muscle cells and cardiac myocytes, leading to relaxation of blood vessels and reduced peripheral vascular resistance. The combined effect results in effective blood pressure reduction with minimal reflex tachycardia.

Mechanism Steps

1
Telmisartan blocks AT1 receptors: Telmisartan binds to and blocks angiotensin II type 1 receptors in vascular smooth muscle and adrenal cortex, preventing angiotensin II from causing vasoconstriction and aldosterone release.
2
Azelnidipine inhibits calcium channels: Azelnidipine blocks L-type calcium channels in vascular smooth muscle cells, reducing calcium influx and causing relaxation of blood vessels.
3
Combined vasodilation: The two mechanisms work together to dilate blood vessels, reduce peripheral resistance, and lower blood pressure effectively.

💡 How to Take azusa t 8/40 tablet

Strength: Tablet containing Telmisartan 40 mg and Azelnidipine 8 mg.

1Take the tablet orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it at the same time each day, with or without food.
4If you have a sensitive stomach, take it with a meal.
5Do not take an extra dose if you miss one; follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dose adjustment is required for mild to moderate renal impairment. In severe renal impairment or dialysis patients, use with caution and monitor potassium and creatinine levels. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe hepatic impairment. Dose must be individualized by a qualified clinician.
Maximum Daily DoseOne tablet (Telmisartan 40 mg + Azelnidipine 8 mg) once daily. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of azusa t 8/40 tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid driving if dizzy. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe or persistent.
Peripheral edema (Common (5-10%))
Elevate legs when sitting. Reduce salt intake. Consult doctor if swelling worsens.
Fatigue (Common (5-10%))
Get adequate rest. Avoid strenuous activity until you know how this medicine affects you.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or blurred vision.
Hyperkalemia (Rare (<0.1%))
Report muscle weakness, irregular heartbeat, or numbness. Regular blood tests may be needed.
Acute kidney injury (Rare (<0.1%))
Seek medical help if you notice decreased urine output, swelling, or confusion.
Angioedema (Very rare (<0.01%))
Stop the medicine and seek emergency care immediately if you experience swelling of face, lips, tongue, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Allergic reactions
Seek medical attention if you develop rash, itching, or hives.
Liver enzyme elevation
Report yellowing of skin or eyes, dark urine, or abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Spironolactone Major
Ibuprofen Major
Lithium Major
Ketoconazole Moderate
Rifampin Moderate

🚨 Major Interactions

  • Potassium-sparing diuretics (e.g., spironolactone)
  • NSAIDs (e.g., ibuprofen)
  • Lithium

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., rifampin)

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Severe hepatic impairment","Biliary obstructive disorders","History of angioedema with ARBs","Concomitant use with aliskiren in patients with diabetes","Severe renal artery stenosis"]

⚠️ Warnings & Precautions

["Avoid use in pregnancy; can cause fetal harm.","Monitor potassium levels; risk of hyperkalemia.","May cause symptomatic hypotension, especially in volume-depleted patients.","Use with caution in patients with aortic or mitral stenosis.","May impair kidney function; monitor renal status.","Avoid abrupt withdrawal; taper if needed.","Not recommended in children."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.

💊 Overdose Management

Overdose may cause severe hypotension, dizziness, and electrolyte imbalances. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic. Gastric lavage may be considered if taken recently. Monitor vital signs and electrolytes closely.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Monitor your blood pressure regularly and keep a record to share with your doctor. Avoid alcohol while taking this medicine, as it can enhance the blood pressure-lowering effect and cause dizziness. Do not take potassium supplements or salt substitutes containing potassium without consulting your doctor, as this medicine can increase potassium levels. Inform your doctor if you have kidney or liver disease, diabetes, or are planning to become pregnant. Use effective contraception while taking this medicine, as it can harm the unborn baby. If you experience symptoms like severe dizziness, fainting, or swelling of the face or throat, seek emergency medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Start with a lower dose and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid blood pressure fluctuations during the procedure.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking or swimming.
😴
Reduce salt intake to less than 5 grams per day.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep and follow a regular sleep schedule.

🏋️ Exercise Considerations

This medicine may cause dizziness, especially when starting treatment or changing doses. Avoid strenuous exercise or heavy lifting until you know how it affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Follow a DASH diet rich in fruits, vegetables, and whole grains.
Limit sodium intake to less than 5 grams per day.
Include potassium-rich foods like bananas and spinach, but monitor if you have kidney issues.
Avoid processed and high-fat foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue your daily activities, but take precautions.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like angioedema or severe hypotension, seek immediate medical attention and follow your doctor's advice on discontinuation.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing hypertension. Regular monitoring of blood pressure, kidney function, and electrolytes is recommended. It may reduce the risk of cardiovascular events. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help lower blood pressure and complement medication.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, beta-blockers, or diuretics may be alternatives based on individual patient profile.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust the timing of your dose gradually under medical guidance. Keep enough supply for the entire trip and carry it in your hand luggage. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension not controlled on monotherapy
He was prescribed this medicine once daily. After 4 weeks, his blood pressure stabilized, and he reported feeling more energetic. He experienced mild ankle swelling initially, which resolved after elevating his legs and reducing salt intake.
💡 Lesson: Combination therapy can effectively control blood pressure when monotherapy fails. Mild side effects often improve with simple measures.
👤 A 62-year-old woman with diabetes and hypertension
She started this medicine and noticed improvement in her blood pressure readings. She was advised to monitor her kidney function and potassium levels regularly. She remained compliant with her diet and medication.
💡 Lesson: Regular monitoring of kidney function and electrolytes is crucial for patients on this medicine, especially those with diabetes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but maximum effect may take 2-4 weeks of regular use.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for azusa t 8/40 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure high blood pressure permanently.
    Fact: This medicine controls blood pressure but does not cure hypertension. Lifestyle changes and long-term medication are often needed.
  • Myth: You can stop taking this medicine once your blood pressure is normal.
    Fact: Stopping suddenly can cause a rebound increase in blood pressure. Always consult your doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Telmisartan 40 mg + Azelnidipine 8 mg tablet

Brand Alternatives

  • Azovas T 40 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Telmisartan + Azelnidipine","composition":"Telmisartan 40 mg + Azelnidipine 8 mg","class":"ARB + CCB","usual_dose":"Once daily"},{"medicine":"Telmisartan + Amlodipine","composition":"Telmisartan 40 mg + Amlodipine 5 mg","class":"ARB + CCB","usual_dose":"Once daily"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory